Presentation
Her history included a diarrhoea syndrome 2 months before the present admission, during the summer holidays, for which she was treated with metronidazole. [ncbi.nlm.nih.gov]
Immune System
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Axillary Lymphadenopathy
Physical examination revealed slight hepatomegaly and splenomegaly, as well as cervical and axillary lymphadenopathy. [ncbi.nlm.nih.gov]
Entire Body System
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Lymphadenopathy
Physical examination revealed slight hepatomegaly and splenomegaly, as well as cervical and axillary lymphadenopathy. [ncbi.nlm.nih.gov]
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Intermittent Fever
Abstract A 16-year-old Caucasian girl of Albanian origin was admitted to the hospital complaining of intermittent fever (38 degrees C) for a week, nausea, vomiting, and abnormal laboratory findings (elevated serum aminotransferases levels AST/ALT 77/40 [ncbi.nlm.nih.gov]
Gastrointestinal
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Nausea
Both assemblages caused similar illness, but assemblage AII was significantly more frequently associated with abdominal pain, nausea and vomiting. [ncbi.nlm.nih.gov]
Symptoms include diarrhea, abdominal pain, anorexia, bloating, nausea, and vomiting. [sharinginhealth.ca]
Diarrhea is the major symptom of the disease but the clinical manifestations vary; from non-symptomatic infections to severe diarrhea, abdominal cramps, bloating and flatulence often accompanied by nausea and weight loss. [certest.es]
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Abdominal Pain
Both assemblages caused similar illness, but assemblage AII was significantly more frequently associated with abdominal pain, nausea and vomiting. [ncbi.nlm.nih.gov]
Symptoms include diarrhea, abdominal pain, anorexia, bloating, nausea, and vomiting. [sharinginhealth.ca]
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Failure to Thrive
In chronic giardiasis, symptoms are recurrent and can lead to failure to thrive, malabsorption and debilitation. return to top Diagnosis Giardiasis is diagnosed by the identification of cysts or trophozoites in the feces, using direct mounts as well as [sharinginhealth.ca]
It can also be misdiagnosed as celiac disease or failure to thrive syndrome. Symptoms can last for two to three weeks, with gradual improvement. [innvista.com]
Symptoms are usually chronic and intermittent, characterized by diarrhea without blood or mucus, flatulence, abdominal pain, belching, malabsorption, and failure to thrive or lack of weight gain. [aafp.org]
In children there may be failure to thrive as a result of the prolonged infection. The epidemiology of Giardiasis has been strongly associated with overseas travelers and wilderness hikers. [dlslab.com]
Possible complications Failure to thrive (children) or malabsorption. [patient.info]
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Odynophagia
We describe the case of a 51-year-old woman presenting with dysphagia, odynophagia, long-lasting low-grade fever, and malabsorption syndrome who underwent an upper gastrointestinal endoscopy showing esophageal candidiasis. [ncbi.nlm.nih.gov]
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Melena
He reported foamy stools but no blood or melena and had crampy epigastric pain. He denied usage of antibiotics. [ncbi.nlm.nih.gov]
Neurologic
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Responsiveness Decreasing
The IgG/M response decreased more gradually but remained significantly higher than presumed unexposed controls at all time points, except for anti-VSP3 at 12 months. [ncbi.nlm.nih.gov]
Workup
Relying on disease-specific surveillance systems for detection of outbreaks is not sufficient when the pathogen is difficult to diagnose, or when it is non-endemic in the area and therefore not part of the routine diagnostic workup. [doi.org]
Microbiology
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Tropheryma Whipplei
Abstract Whipple's disease is a rare systemic condition resulting from a chronic infection by Tropheryma whipplei. Clinical presentation can be widely heterogeneous, often leading to delayed diagnosis and treatment. [ncbi.nlm.nih.gov]
Treatment
Approximately 1 week after treatment all samples tested negative, indicating rapid clearance of parasitic DNA after successful treatment. 2014 The Authors Clinical Microbiology and Infection 2014 European Society of Clinical Microbiology and Infectious [ncbi.nlm.nih.gov]
Prognosis
[ 17 ] Prognosis The prognosis is usually good. [patient.info]
What Is the Prognosis for Giardiasis? Cure rates are high with appropriate medication in an otherwise healthy person. [emedicinehealth.com]
Etiology
Abstract Giardia lamblia is the etiologic agent of giardiasis, a water-borne infection that is prevalent throughout the world. The need for new therapeutics for the treatment of giardiasis is of paramount importance. [ncbi.nlm.nih.gov]
The English and the French, especially, believed it to be the etiologic agent in many cases of "trench diarrhea." [jamanetwork.com]
Etiology Pathogen : Giardia lamblia ; (also known as Giardia intestinalis or duodenalis ), a protozoan Transmission Waterborne: from drinking of recreational water (e.g., lakes, rivers, ponds, swimming pools) Fecal-oral (e.g., through food handlers, people [amboss.com]
Diarrhea in returning Austrian tourists: epidemiology, etiology, and cost analyses. J Travel Med. 1998;5(2):65-72. PMID: 9772320; doi: 10.1111/j.1708-8305.1998.tb00466.x. [ Links ] 23. Choy SH, Al-Mekhlafi HM, Mahdy MA, et al. [scielo.br]
Epidemiology
INTRODUCTION: Though giardiasis is an important public health problem in Ghana, several aspects of its epidemiology, particularly the molecular epidemiology has not been investigated adequately. [ncbi.nlm.nih.gov]
Pathophysiology
The pathophysiology may arise from enzyme or active transport deficiencies, synergy with intestinal bacteria or an immunopathological process. Diagnosis is made by microscopic identification of cysts or trophozoites in small bowel samples or faeces. [karger.com]
Pathophysiological aspects of enteric infections with the lumen-dwelling protozoan pathogenGiardia lamblia, American Journal of Physiology-Gastrointestinal and Liver Physiology, 280, 1, (G1), (2001). [doi.org]
References: [2] Pathophysiology Clinical features Infection with Giardia lamblia must be considered as a differential diagnosis for persistent diarrhea. 3–25 days after ingestion of cysts diarrhea consisting of soft, voluminous, frothy, and greasy stools [amboss.com]
The following algorithms are available in Special Instructions: -Parasitic Investigation of Stool Specimens Algorithm -Laboratory Testing for Infectious Causes of Diarrhea Clinical Information Discusses physiology, pathophysiology, and general clinical [mayomedicallaboratories.com]
Prevention
Prevention and Control Key Laboratory, College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China. [email protected] [ncbi.nlm.nih.gov]