Presentation
These pediatric cases underscore the limitations of relying solely on clinical presentation and neuroimaging and call to attention the essential role of neurosurgical intervention. [ncbi.nlm.nih.gov]
Entire Body System
- Weakness
A 45-year-old female presented with gliomatosis cerebri manifesting as hemiballismus-like involuntary movement in the arm, motor weakness in the leg, and hypesthesia in her left side. [ncbi.nlm.nih.gov]
Allie’s Symptoms Voracious appetite/weight gain (hypothalamus obesity) Partial facial paralysis Seizures Headache Short-term memory loss Weakness and numbness in the limbs Trouble sleeping GC Registry The Children’s Brain Tumor Project launched the International [teamlittleowl.org]
Symptoms of gliomatosis cerebri depend on what parts of the brain are affected and include: Signs of raised pressure in the brain (seizures, nausea, vomiting, drowsiness, headaches) Personality and behavioral changes Localized symptoms (like weakness [nicklauschildrens.org]
The patient originally was right-handed active softball player, but grasping power was weak with 21 kg on the right and 29 kg on the left at the time. [jcmtjournal.com]
- Progressive Dementia
The following is a case report of a 14-year-old female who had a subtotal cortical resection of tumor and several years later developed a progressive dementia. At postmortem examination the diagnosis of gliomatosis cerebri was made. [ncbi.nlm.nih.gov]
A case of gliomatosis cerebri presenting as rapidly progressive dementia and Parkinson's disease like symptoms has been described in an 82-year-old woman. Before the advent of MRI, diagnosis was generally not established until autopsy. [en.wikipedia.org]
Discussion The association of parkinsonism, falls and dementia is suggestive of a dementia with Lewy bodies [ 4 ]. Indeed, very rapidly progressing dementias with Lewy bodies have been described [ 5, 6 ]. [jmedicalcasereports.biomedcentral.com]
Session Information Session Time: 1:45pm-3:15pm Location: Exhibit Hall C Objective : Report a case of rapidly progressive dementia and parkinsonism related to gliomatosis cerebri. [mdsabstracts.org]
Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman: a case report. J Med Case Reports 2008;20;2:53. 10. Maramattom BV, Giannini C, Manno EM, Wijdicks EF, Campeau NG. [neurologyindia.com]
- Whipple Disease
Syphilis, HIV infection, Lyme neuroborreliosis, herpes virus, toxoplasmosis, cryptococcus, cytomegalovirus, or more rarely, Whipple diseases are few of the infectious causes of behavioral changes including dementia. [6] Besides few isolated reports of [jnsbm.org]
- Gaucher Disease
These include familial Alzheimer's disease, spinocerebellar ataxia 17 (dominant inheritance), adrenoleukodystrophy (X-linked), Gaucher's disease type 3, metachromatic leukodystrophy, Niemann-Pick disease type C, pantothenate kinase-associated neurodegeneration [jnsbm.org]
Gastrointestinal
- Nausea
Symptoms of gliomatosis cerebri depend on what parts of the brain are affected and include: Signs of raised pressure in the brain (seizures, nausea, vomiting, drowsiness, headaches) Personality and behavioral changes Localized symptoms (like weakness [nicklauschildrens.org]
You know, “chemo brain,” issues with steroids, fatigue, nausea, etc. Could be MUCH worse. Now, coming to the fact that I might lose my hair…It doesn’t bother me. [braintumor.org]
So side effects, he has a shaved head and massive issues with nausea from the chemo. Otherwise - his problems have been with the continued detoriation of his right side where the largest tumor is pressing against the motor strip. [cancercompass.com]
Psychiatrical
- Auditory Hallucination
The current patient had obsessive images, anxiety, auditory hallucinations and seizures following (possible) gliomatosis cerebri, with onset around 69 years of age. [ncbi.nlm.nih.gov]
- Compulsive Disorder
Onset of obsessive-compulsive disorder (OCD) after the age of 50 years is rare, and should alert the physician to possible "organic" causes of OCD. [ncbi.nlm.nih.gov]
Urogenital
- Nocturnal Enuresis
SB was also reported to have new onset nocturnal enuresis and headaches. She had been observed to have reduced concentration and dropping school performance in the previous term. [austinpublishinggroup.com]
Neurologic
- Headache
The very few cases reported in children have presented with intractable epilepsy, corticospinal tract deficits, unilateral tremor, headaches, and developmental delay. [ncbi.nlm.nih.gov]
Clinical manifestations are indefinite, and include headache, seizures, visual disturbances, corticospinal tract deficits, lethargy, and dementia. [en.wikipedia.org]
- Involuntary Movements
A 45-year-old female presented with gliomatosis cerebri manifesting as hemiballismus-like involuntary movement in the arm, motor weakness in the leg, and hypesthesia in her left side. [ncbi.nlm.nih.gov]
- Hand Tremor
Case Report A 69-year-old woman was admitted to our hospital with a 5-month history of progressive memory loss, personality change, right hand tremor, right-sided weakness, and fatigue. The patient also had experienced an episode of gait imbalance. [ajnr.org]
Workup
Here, we report the diagnostic workup of 2 patients with gliomatosis cerebri, discussing the clinical, radiologic, and pathologic findings. [ncbi.nlm.nih.gov]
She had an extensive workup for autoimmune (Anti-Ro/La, ANA, anti-dsDNA, anti-cardiolipin antibodies, RNP, RF), granulomatous (ANCA, ACE), infectious (encephalitis panel, VZV, HIV, Borrelia, Brucella, HTLV, Syphilis, Coccidiomycosis, Entamoeba, Mycobacterium [n.neurology.org]
Other Pathologies
- White Matter Lesions
Patients with hematological malignancies may develop white matter lesions, which are usually associated with chemotherapy. [ncbi.nlm.nih.gov]
Treatment
Relief of intracranial hypertension allowed further treatment and a survival of 23 months. Relevant literature on the subject has been reviewed. [ncbi.nlm.nih.gov]
Prognosis
Real-time expression values relative to these 23 gene features were used to build a prediction method able to distinguish patients with a good prognosis (those more likely to be responsive to therapy) from patients with a poor prognosis (those less likely [ncbi.nlm.nih.gov]
Etiology
Dementia in younger people usually has some demonstrable secondary etiology (psychiatric illness, alcohol or drugs or metabolic disturbance, familial Alzheimer's disease, Wilson's disease, etc). [jnsbm.org]
Conclusions: It is important to consider neoplastic etiologies in the differential of granulomatous processes, even when preliminary neoplastic evaluation is unremarkable. Disclosure: Dr. LaBuzetta has nothing to disclose. Dr. [n.neurology.org]
The histogenesis of GC is greatly debated, and because its origin remains unknown, it was withdrawn from the category of embryonic tumor and is currently classified as neuroepithelial neoplasia of unknown etiology with grade III or IV of malignancy. [scielo.br]
Epidemiology
Histology of Gliomatosis cerebri often low malignancy of cells because of the special growth pattern it is classified as WHO grade III Epidemiology of Gliomatosis cerebri usually in median and high adult age can also occur in children Symptoms of Gliomatosis [hirntumorhilfe.org]
OBJECTIVE: We used the SEER (Surveillance Epidemiology and End Results) database (1999-2010) to analyze the clinical practice patterns and overall survival in patients with gliomatosis cerebri (GC), or glioma involving 3 or more lobes of the cerebrum. [ncbi.nlm.nih.gov]
Epidemiology Peak incidence is between 40 and 50 years. Both genders are equally affected. Localization The primary nosological characteristic of gliomatosis cerebri is its diffuse growth pattern. [prod.wiki.cns.org]
Heart, 97(9): 766-73 [ CR ] [ PM ] [ EČ ][ 1 ][ GS ] Shamseddin, K.M., Parfrey, P.S. (2011) Sudden cardiac death in chronic kidney disease: epidemiology and prevention. [scindeks.ceon.rs]
Pathophysiology
Semin Dial, 12(2): 77 [ CR ] [ PM ] [ EČ ][ GS ] London, G.M. (2003) Cardiovascular disease in chronic renal failure: pathophysiologic aspects. [scindeks.ceon.rs]
Understanding the tumor pathophysiology and specifically the biology behind the extreme invasiveness of tumor cells is a first step toward developing novel therapeutics for GC. [journal.frontiersin.org]
Prevention
Analysis of preventability of malignancy-related maternal death from the nationwide registration system of maternal deaths in Japan. [dx.doi.org]
Am J Crit Care, 13(6): 453-66; quiz 467-8 [ CR ] [ PM ] [ EČ ][ 1 ][ GS ] Herzog, C.A. (2007) Can we prevent sudden cardiac death in dialysis patients?. [scindeks.ceon.rs]
One question I thought to ask: in all of your messages and postings about different treatments, you have never mentioned the so-called cytostatic drugs like Bevacizumab, which is an angiogenesis inhibitor i.e. it prevents the creation of blood supply [cancerforums.net]
Progression-free survival is greatly improved with complete rather Surgery via ‘open door maxillotomy’ is the mainstay of treatment, but the location and invasive nature often prevents complete resection necessitating adjuvant radiotherapy. [aibolita.com]