A 49-year-old man with a 1-month history of episodic, severe abdominal pain sought medical attention. The patient's history was remarkable for type II diabetes, for which glipizide therapy had been initiated 2 months earlier. [ncbi.nlm.nih.gov]

Adverse Reactions: Lactic acidosis (rare, ½ the cases are fatal), GI upset, abdominal pain, upper respiratory infection, headache, dizziness, hypertension, musculoskeletal pain, hypoglycemia. Note: Formerly known under the brand name Metaglip. [empr.com]

pain, headache, abdominal pain, and urinary tract infection. 153 Potential pharmacokinetic interaction with other protein-bound drugs. 1 2 47 72 80 Absorption is essentially complete; 1 30 31 32 33 34 35 36 37 38 80–100% of an oral dose may be absorbed [drugs.com]

After simple protein precipitation with methanol including 4'-OH-tolbutamide and gliclazide (both are internal standards), the analytes were chromatographed on a reversed-phased column with a mobile phase of 0.1% formic acid in acetonitrile and 0.1% formic [ncbi.nlm.nih.gov]

Fasting blood glucose decreased in the repaglinide group by 2.4 mmol/l and increased in the glipizide group by 1.0 mmol/l (P 0.05 between groups). [ncbi.nlm.nih.gov]