The pathogenesis of this disorder is unclear and is known to occur in patients with hypertension, hypercholesterolemia, history of chronic smoking, chronic obstructive pulmonary disease with chronic hypoxemia, obesity, etc.[ 7, 8 ] Despite the growing [ncbi.nlm.nih.gov]

Although she had no symptoms of either myopathy or encephalopathy, no history of stroke-like episodes or difficulty in hearing, her serum concentrations of lactate and pyruvate were both elevated. [ncbi.nlm.nih.gov]

Untreated, it can lead to kidney failure. In some cases, kidney failure can occur despite treatment. FSGS most frequently occurs without a cause. In such cases it is called idiopathic or primary FSGS. [webmd.com]

If kidney failure does occur, treatment options are available. [davita.com]

The goal of treatment is to control the symptoms of nephrotic syndrome and prevent chronic kidney failure. [mountsinai.org]

Kidney failure is a common outcome. glomerulosclerosis progressive hyalinization such that glomeruli become shrunken, eosinophilic and hypocellular masses. intercapillary glomerulosclerosis [medical-dictionary.thefreedictionary.com]

In one cat, an islet showed a dense lymphocytic infiltration. — No lesions identical to human diabetic glomerulosclerosis were found in any of the dogs or cats. [glosbe.com]

Vessels and tubulointerstitium were unremarkable except for focal lymphocytic infiltrates. Immunofluorescence was negative for IgM, IgA, IgG, C3C, C1q, k, and λ. [ncbi.nlm.nih.gov]