G6PD assay show marked decrease in enzyme level at time of presentation in all cases with the commonest G6PD enzyme level of 3-4 U/gm Hb (592 patients; 59.2%). [ncbi.nlm.nih.gov]

• Anemia

  The anemia that results is a nonspherocytic hemolytic anemia. See also congenital nonspherocytic hemolytic anemia, favism. [medical-dictionary.thefreedictionary.com]

  His response to antibiotic therapy was optimal; the hemolytic anemia resolved. There were no further episodes of hemolysis. [ncbi.nlm.nih.gov]

• Fatigue

  In the acute phase, pyrexia, severe general fatigue, lumbar back pain, hemoglobinuria, and jaundice developed. Laboratory blood examinations showed hemolysis, and remarkable increases in serum ferritin and cytosol leucine aminopeptidase levels. [ncbi.nlm.nih.gov]

  · Pallor · Fatigue · Tachycardia –quick heart rate · Yellow skin · Shortness of breath · Dark colored urine Incidence and Carriers Disease frequency: 400 million people worldwide. approximately 50% of Kurdish males, 30% of Sardinia males, and 13% of [mazornet.com]

  Reaction to these drugs vary according to variant and other conditions, such as fatigue, stress level, altitude, etc. Please consult with your pediatrician or physician before taking any of these. [g6pd.org]

• Pallor

  Patients presented mainly with pallor (1000 patients; 100%), dark red urine (896 patients; 89.6%) and jaundice (878 patients; 87.8%) after 24-72 hours of exposure to the precipitating factors (mean: 36 17.73 hours). [ncbi.nlm.nih.gov]

  · Pallor · Fatigue · Tachycardia –quick heart rate · Yellow skin · Shortness of breath · Dark colored urine Incidence and Carriers Disease frequency: 400 million people worldwide. approximately 50% of Kurdish males, 30% of Sardinia males, and 13% of [mazornet.com]

  Within 24 hours he developed increasing pallor (Hb 41 g/l, haematocrit 12.4%, SBR 98 μmol/l, LDH 827 U/l), tachycardia, and poor peripheral perfusion. After transfusion his jaundice subsided, and his Hb remained stable. [doi.org]

• Hypothermia

  Abstract Cardiac surgery involving cardiopulmonary bypass (CPB) in its conventional form involves many processes leading to free radical production, such as perioperative ischemia, reperfusion, circulation of whole body blood through the CPB circuit, hypothermia [ncbi.nlm.nih.gov]

• Abdominal Pain

  The patient experienced abdominal pain and acute hypotension 10 minutes after diagnostic hysteroscopy. We attributed this event to the exposure of her genital mucosa caused by the hysteroscopic chemical disinfectant. [ncbi.nlm.nih.gov]

  pain localized to the right upper quadrant area of his abdomen. [osmosis.org]

  Recurring hemolytic crises may occur, especially following triggers Arises within 2–3 days after increased oxidative stress Sudden onset of bac k or abdominal pain Jaundice Dark urine Transient splenomegaly Recurrent severe infections causing symptoms [amboss.com]

  pain and jaundice secondary to a rise in unconjugated bilirubi n ( Table 5 21 ). [aafp.org]

• Nausea

  Nausea, abdominal pain and diarrhea may develop. Vomiting only occurs rarely. Within 6 to 24 hours, urine may become noticeably dark and can appear red, brown or even black. [rarediseases.org]

  An attack by P. vivax causes agonising daily paroxysms often accompanied by intractable nausea and vomiting, headache, myalgia and profound asthenia. 21 Anstey NM, Douglas NM, Poespoprodjo JR, Price RN. [doi.org]

• Upper Abdominal Pain

  CASE REPORT A 35-year-old man with no history of alcoholism or liver disease presented with low grade fever, upper abdominal pain, fatigue and loss of appetite for eight to 10 days. [ncbi.nlm.nih.gov]

• Jaundice

  Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the commonest enzyme disorder of human beings and a globally important cause of neonatal jaundice, which can lead to kernicterus and death or spastic cerebral palsy. [ncbi.nlm.nih.gov]

  Follow up at three months showed no residual jaundice, no sign of kernicterus, normal hearing, Hb 100 g/l, reticulocytes 3.9%. [doi.org]

• Scleral Icterus

  icterus Coombs’ test Negative Drugs that cause hemolysis in G6PD-deficient persons inf lict oxidative damage to erythrocytes leading to erythrocyte destruction. [aafp.org]

• Normal Hearing

  Follow up at three months showed no residual jaundice, no sign of kernicterus, normal hearing, Hb 100 g/l, reticulocytes 3.9%. [doi.org]

• Dark Urine

  This type of anemia leads to paleness, yellowing of the skin and whites of the eyes ( jaundice ), dark urine, fatigue, shortness of breath, and a rapid heart rate. [medicinenet.com]

  His major complaint was preceded, in sequence, by a temperature of 102 F (38.9 C), dark urine, [jamanetwork.com]

  Symptoms during a hemolytic episode may include dark urine, fatigue, paleness, rapid heart rate, shortness of breath, and yellowing of the skin ( jaundice ). [rarediseases.info.nih.gov]

  Recurring hemolytic crises may occur, especially following triggers Arises within 2–3 days after increased oxidative stress Sudden onset of bac k or abdominal pain Jaundice Dark urine Transient splenomegaly Recurrent severe infections causing symptoms [amboss.com]

  Symptoms are more common in men and may include: Dark urine Fever Pain in abdomen Enlarged spleen and liver Fatigue Pallor Rapid heart rate Shortness of breath Yellow skin color ( jaundice ) Treatment Treatment may involve: Medicines to treat an infection [mountsinai.org]

• Kidney Failure

  The evolution was marked by a respiratory distress syndrome, a severe hemolytic anemia, associated with thrombocytopenia and kidney failure. [ncbi.nlm.nih.gov]

  In rare case, kidney failure or death may occur following a severe hemolytic event. Call your health care provider if you have symptoms of this condition. [nlm.nih.gov]

  If a severe hemolytic event occurs and is not treated, kidney failure or death can occur. But this is very rare. [explainmedicine.com]

  Possible Complications In rare case, kidney failure or death may occur following a severe hemolytic event. When to Contact a Medical Professional Call your health care provider if you have symptoms of this condition. [mountsinai.org]

• Anisopoikilocytosis

  The peripheral blood smear showed polychromasia, anisopoikilocytosis and reticulocytosis (the reticulocyte count was 14.6%). Urine was positive for hemoglobinuria. [ncbi.nlm.nih.gov]

• Normocytic Normochromic Anemia

  There was normocytic normochromic anemia with reticulocytosis and Heinz bodies in pre-transfusion complete blood picture in all studied cases. [ncbi.nlm.nih.gov]

• Hyperviscosity

  Several possible mechanisms exist to explain this association, including hyperviscosity, direct endothelial dysfunction secondary to bare hemoglobin vasculotoxicity, and relative nitric oxide deficiency causing vasoconstriction and vascular smooth muscle [ncbi.nlm.nih.gov]

The patient underwent adjuvant radiotherapy; meanwhile, tamoxifen was administered as adjuvant endocrine treatment. The treatment process was smooth. There was no evidence of hemolytic anemia. [ncbi.nlm.nih.gov]

The main treatment for G6PD deficiency is avoidance of oxidative stressors. [aafp.org]

Current evidence suggests that PVB19-associated HLH has a favorable prognosis. Mild undiagnosed cases of HLH may be the cause of pancytopenia in PVB19 infections. [ncbi.nlm.nih.gov]

Links: drugs to avoid in G6PD deficiency clinical features investigations treatment and prognosis [gpnotebook.co.uk]

Prognosis The prognosis for almost everyone with G6PD deficiency is excellent. Large studies have shown that G6PD-deficient individuals do not acquire any illnesses more frequently than the rest of the population. [medical-dictionary.thefreedictionary.com]

Pallor Rapid heart rate Shortness of breath Yellow skin color ( jaundice ) Treatment Treatment may involve: Medicines to treat an infection, if present Stopping any drugs that are causing red blood cell destruction Transfusions, in some cases Outlook (Prognosis [mountsinai.org]

Often the etiology is idiopathic. Three cases of priapism in glucose-6-phosphate dehydrogenase (G6PD) deficiency patients have been described in literature. [ncbi.nlm.nih.gov]

Etiology of hemolysis in two patients with hepatitis A infection: glucose-6-phosphate dehydrogenase deficiency or autoimmune hemolytic anemia. Eur J Pediatr. 2008 Dec. 167(12):1435-9. [Medline]. [emedicine.com]

/analysis/complications/diagnosis/epidemiology; mass screening; military medicine; retrospective studies; risk assessment; risk factors [ncbi.nlm.nih.gov]

It provides epidemiologists, physicians, sociologists, and anthropologists with a methodological framework for understanding the concepts of race and ethnic group, the use of these concepts in epidemiology, and the interpretation of epidemiologic studies [books.google.es]

The medical condition generates a pathophysiologic milieu consistent with aberrant NO signaling and heightened oxidative stress in the penis. [ncbi.nlm.nih.gov]

The complications of G6PD deficiency can largely be prevented by education and information, and neonatal jaundice can be successfully treated by phototherapy, a cheap and simple approach suitable for use in primary health care. [ncbi.nlm.nih.gov]