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Glue Sniffing
Glue Sniffing (inhalant Abuse)

Images

WIKIDATA, CC BY-SA 2.0

Presentation

The habit of glue sniffing is now widespread amongst Australian adolescents and this factor should be considered when any young person presents with a peripheral neuropathy. [ncbi.nlm.nih.gov]

Phillip also went on to reveal, as he got stuck in to making the pin-cushions, that he ‘turned down’ the chance to present Blue Peter many years ago. [metro.co.uk]

Sensations resembling acute alcoholic intoxication are induced by self-exposure to the volatile organic solvents variously present in model airplane glues. [jamanetwork.com]

Entire Body System

  • Rapidly Progressive Glomerulonephritis

    A 16-year-old girl developed rapidly progressive glomerulonephritis and renal failure. [ncbi.nlm.nih.gov]

Gastrointestinal

  • Overeating

    […] shrieked Holly as she mortified over Phillip’s gift. [express.co.uk]

    At autopsy, conjunctival and visceral congestion were found with pulmonary edema and petechiae over visceral pericardium. The viscera were analyzed, and the presence of toluene in his liver and blood was reported. [ncbi.nlm.nih.gov]

    Solvent abuse accounts for a death rate of over 70 people a year, the vast majority being under 20 years old. [urban75.com]

    Sadly, street children the world over abuse solvents – and the inhalant most commonly used is the glue for mending shoes. [streetchildunited.org]

  • Nausea

    Background From the Division of Alcohol and Drug Abuse I learned the following: Initial effects [of various inhalants] include nausea [...], and a loss of appetite. [biology.stackexchange.com]

    Here are other signs the AAP says to look for: A chemical smell, paint, or stains on clothing or the child's body Spots or sores around the mouth A drunk, dazed, or glassy-eyed look Nausea, loss of appetite Anxiety, excitability, irritability Watch Out [familyeducation.com]

    Some of the side effects of glue sniffing include: Damage to the nasal passages Damage to lungs and trachea Persistent cough or wheezing, even coughing up of blood Nausea and vomiting Brain Damage Kidney Failure Depression Lack of school and social participation [selectown.com]

Skin

  • Petechiae

    At autopsy, conjunctival and visceral congestion were found with pulmonary edema and petechiae over visceral pericardium. The viscera were analyzed, and the presence of toluene in his liver and blood was reported. [ncbi.nlm.nih.gov]

Psychiatrical

  • Euphoria

    […] glue-snif·fing | \ ˈglü-ˌsnif-iŋ \ Medical Definition of glue-sniffing : the deliberate inhalation of volatile organic solvents from plastic glues that may result in symptoms ranging from mild euphoria to disorientation and coma [merriam-webster.com]

    Symptoms vary from mild euphoria and exhilaration to gross disorientation and coma after prolonged inhalation. Physiological addiction evidently does not occur, but psychological dependency is common. [jamanetwork.com]

    Solvent abuse Substance abuse A potentially fatal form of substance abuse, more often practiced by young ♂ adolescents, in which model glue is placed in a paper or plastic bag and deeply sniffed to obtain the maximum desired effect–a combination of euphoria [medical-dictionary.thefreedictionary.com]

    Glue sniffing became popular with young adolescents who experimented with model aeroplane glue and found that by sniffing the vapours a feeling of euphoria and exhilaration was achieved. [medicalonline.com.au]

    It involves voluntarily inhalation of glue or a rag soaked in glue to induce a sense of euphoria. Glue sniffing is a form of addiction largely due to the effects of the substance toluene within these preparations. [healthhype.com]

  • Impulsivity

    By affecting the transmission of nerve impulses and neurotransmitters (brain hormones), it has a host of central nervous system effects. However, toluene also affects a host of other systems. [healthhype.com]

  • Psychiatric Symptoms

    We retrospectively reviewed the psychiatric symptoms and the results of cognitive tests for six long-term glue sniffers admitted to a psychiatric ward. [ncbi.nlm.nih.gov]

  • Self-Mutilation

    Our results suggest that long-term abuse of these adhesive products is often associated with violent behavior and/or self-mutilation. [ncbi.nlm.nih.gov]

Urogenital

  • Oliguria

    The high urinary spot sodium during the oliguric phase and the total renal functional recovery after a period of oliguria followed by polyuria favoured a diagnosis of acute toxic tubular necrosis causing acute renal failure. [ncbi.nlm.nih.gov]

Neurologic

  • Headache

    Acute Exposure With acute unintentional exposure from toluene-containing household products, symptoms may include dizziness, rapid breathing, shortness of breath, headaches, hallucinations, seizures and even unconsciousness. [healthhype.com]

    Side effects include depression, hallucinations, headaches and muscle weakness. Long term glue sniffing causes serious heart, lung, liver and kidney damage, and often causes heart failure or brain damage which leads to death. [rehab-recovery.co.uk]

    A bit dizzy, but no headache. I sat down in a chair and waited patiently. It only went down hill from there. I began to notice a very strange feeling, one that is about impossible to describe. It was as if I had no brain, or my head was empty. [erowid.org]

  • Confusion

    an organic solvent Epidemiology ♂:♀ ratio is 5:1–UK, peak abuse 13–15; solvents implicated include toluene, trichloroethylene, trichloroethane, tetrachloroethylene; toluene vapors causes irritation of mucosae, lacrimation, arrhythmias, N&V, mental confusion [medical-dictionary.thefreedictionary.com]

    Inhalants can affect the mind, causing: • Intoxication, over excitement • Confusion, dizziness, disorientation, drowsiness • Slurred speech, impaired judgement, • Changed perception, of time, space, colour, shape, size, feelings of being “spaced out” [crime.co.nz]

    All three looked angry and confused. An older woman sitting near them began, in a strict motherly voice, reprimanding the adults for allowing a child to sniff glue. [strausscenter.org]

    So a sniffer may become drowsy, confused, aggressive, may take more risks than they would when sober, and so on. Accidents are, therefore, quite common and sometimes fatal. Gas fuels continue to be associated with the majority of deaths. [thesite.org]

    […] noticeable to others include : Low blood pressure Sweetish body odor Rapid breathing Rapid heart rate Paleness (pallor) or even a bluish tinge of the skin (cyanosis) More organ and system specific signs of toluene exposure includes : Headaches Dizziness Confusion [healthhype.com]

  • Slurred Speech

    Side effects: Solvent abuse can result in a dazed appearance, unsteadiness, slurred speech and unpredictable behaviour. There is a real risk of vomiting, choking and possibly unconsciousness. [urban75.com]

    Abnormal Glue Aroma Difficulty Concentrating Slurred Speech Lightheadedness Hallucinations Delusions Inhibitions Are Impeded Inability to Control Actions Short Term Negative Effects of Glue Sniffing Inability to Coordinate Hostility, Irritability Compromised [harborvillageflorida.com]

    Drug Education: The symptoms of volatile solvent abuse In the short term, inhalers may experience slurred speech, headaches, vomiting, wheezing, loss of motor co-ordination and hallucinations. [drug-aware.com]

    Other, nonspecific complaints include the following: memory loss, especially loss of short-term memory; delusions or hallucinations; slurred or changed speech; staggering, stumbling, or wide-based ataxic gait; visual and optical changes, such as nystagmus [aafp.org]

  • Ataxia

    Chronic CNS sequelae, termed chronic solvent-induced encephalopathy (CSE), include neuropsychosis and cerebral and cerebellar degeneration with the following [3] : Ataxia Seizures Choreoathetosis Optic and peripheral neuropathies Decreased cognitive ability [emedicine.medscape.com]

    "The signs and symptoms include incoordination, restlessness, excitement, confusion, disorientation, ataxia, delirium, and, finally, coma that may last for a few hours to several days." [druglibrary.org]

    […] fibrosis Sudden sniffing death syndrome Dermatologic effects Burns Contact dermatitis Perioral eczema Gastrointestinal effects Hepatotoxicity Nausea or vomiting Hematologic effects Aplastic anemia Bone marrow suppression Leukemia Neurologic effects Ataxia [aafp.org]

  • Nystagmus

    View/Print Table TABLE 3 Signs and Symptoms of Inhalant Abuse Physical appearance Behavior Paint or oil stains on clothing or body Chemical odor on breath Spots or sores in or around mouth Rhinorrhea Injected sclera Nystagmus Diplopia Stained fingernails [aafp.org]

Treatment

Many cases of huffing result in sniffing gasoline addiction treatment and acetone and solvents addiction treatment. [harborvillageflorida.com]

Our glue sniffing addiction treatment assistance gives you: A free help and evaluation service to help you choose Guidance on the best treatment options for your circumstances Assistance in picking out the most cost-effective options Information on quality [rehab-recovery.co.uk]

After treatment by repeated plasmapheresis and drug immunosuppression autoantibodies disappeared from serum but renal function was not influenced. Renal damage is a potential hazard for glue sniffing adolescents. [ncbi.nlm.nih.gov]

Prognosis

Prognosis Patients with toluene toxicity have a good prognosis if they receive appropriate counseling and follow-up and are compliant with recommendations. The prognosis is poor in patients who continue to abuse toluene. [emedicine.medscape.com]

Etiology

In women with occupational exposure to toluene in the year of or the year before giving birth to a boy, the odds ratio for the child developing a testicular germ cell tumor was 1.67 (95% confidence index, 1.02-2.73). [7] Etiology Inhalation of airborne [emedicine.medscape.com]

Epidemiology

Knowledge of the epidemiology, toxicology, and medical complications associated with glue sniffing is essential in obtaining an accurate history of substance abuse and in clinically managing these patients. [ncbi.nlm.nih.gov]

[…] substance abuse, more often practiced by young ♂ adolescents, in which model glue is placed in a paper or plastic bag and deeply sniffed to obtain the maximum desired effect–a combination of euphoria and CNS depression caused by toluene, an organic solvent Epidemiology [medical-dictionary.thefreedictionary.com]

There are epidemiological reports indicating that chronic exposure to abuse solvents can produce loss of appetite [ 5 ]; however, the mechanisms involved in these effects are not well understood. It’s sad that kids would come to that. [esciencecentral.org]

Although typically thought of as an activity of young males (most deaths occur in young males), epidemiologic studies more than 20 years ago showed more than 50% of chronic solvent abusers were females in their prime childbearing years. [14] A 2006 study [emedicine.medscape.com]

Pathophysiology

Pathophysiology Toluene is highly lipophilic, so it readily crosses the blood-brain barrier, which accounts for its primary effects on the central nervous system (CNS). [emedicine.medscape.com]

^ a b "Inhalants: Background, Pathophysiology, Epidemiology". 5 May 2017. Retrieved 19 July 2017 – via eMedicine. ^ a b c d Schaffer, Amanda (8 September 2004). "Vaporize Me". Slate. [en.wikipedia.org]

Prevention

ASCF’s Craig Burrows wants glue to be treated like raw alcohol: the law requires menthol to be added to it to prevent abuse of a cheap, neat alcoholic drink. [streetchildunited.org]

Once an individual is identified as having Glue Sniffing Addiction then prompt treatment is necessary to prevent any long term complications. [epainassist.com]

According to the VSA Prevention Organisation, Solve It, the youngest person to die from VSA was just seven years old, and the oldest was 80 years old. [drug-aware.com]

Further info: Re-Solv, UK national charity dedicated to the prevention of solvent and volatile substance abuse. [urban75.com]

It was clear that a confrontation would occur if nothing preventative was done. When the train stopped at the next station, one woman went to the door and yelled for security. [strausscenter.org]

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