OBJECTIVES: In this proof-of-principle study, the effectiveness and safety of transdermal administration of neostigmine/glycopyrrolate to elicit a bowel movement was compared to intravenous administration in patients with spinal cord injury. [ncbi.nlm.nih.gov]

Although the disposition of GLY after intravenous administration to Standardbred horses was similar to that in Thoroughbred horses, differences in some pharmacokinetic parameter estimates were evident. [doi.org]

Objectives In this proof-of-principle study, the effectiveness and safety of transdermal administration of neostigmine/glycopyrrolate to elicit a bowel movement was compared to intravenous administration in patients with spinal cord injury. [nature.com]

For intravenous administration, especially where there is a need for protection against bradycardia, the adult dose is 0.2 mg, or on a weight related basis, 4-5 μg/kg, and 5-10 μg/kg in children. [patents.google.com]

gastric emptying, and prolong GI transit time. d Specific Drugs Drug Interaction Comments Amantadine Possible additive anticholinergic effects d Use concomitantly with caution d Antacids Possible decreased absorption of antimuscarinic d Administer oral [drugs.com]

Thirty-four children had cerebral palsy; 1 each had Smith-Lemli-Opitz syndrome, closed head injury, partial trisomy 22, congenital toxoplasmosis, and spinal muscular atrophy. [doi.org]

METHODS: Review of case notes in a series of 24 patients, nine with generalized and 15 with localized hyperhidrosis. RESULTS: Fifteen of 19 evaluable patients (79%) responded to oral glycopyrrolate. [ncbi.nlm.nih.gov]

Methods Review of case notes in a series of 24 patients, nine with generalized and 15 with localized hyperhidrosis. Results Fifteen of 19 evaluable patients (79%) responded to oral glycopyrrolate. [doi.org]

Stamatis Gregoriou, Dimitrios Rigopoulos, Zoe Chiolou, Dafni Papafragkaki, Michalis Makris and George Kontochristopoulos, Treatment of bromhidrosis with a glycine‐soja sterocomplex topical product, Journal of Cosmetic Dermatology, 10, 1, (74-77), (2011 [doi.org]

Third, adverse effects, most commonly behavioral problems, constipation, excessive oral dryness, and urinary retention, cause 20% of developmentally delayed children to stop taking glycopyrrolate. [doi.org]

Not only were subjective complaints of tremor, palpitations, and paresthesias increased for metaproterenol, but the heart rate response was significantly elevated (p less than 0.05) compared with glycopyrrolate. [ncbi.nlm.nih.gov]