Presentation
Other pharmacologic interventions, based on the physiology of erections, are presented. [ncbi.nlm.nih.gov]
Methods of the present invention for orally administering glycopyrrolate compositions may also include the coadministration of adjuvants with the compositions of the present invention. [patents.google.com]
Entire Body System
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Intravenous Administration
OBJECTIVES: In this proof-of-principle study, the effectiveness and safety of transdermal administration of neostigmine/glycopyrrolate to elicit a bowel movement was compared to intravenous administration in patients with spinal cord injury. [ncbi.nlm.nih.gov]
Although the disposition of GLY after intravenous administration to Standardbred horses was similar to that in Thoroughbred horses, differences in some pharmacokinetic parameter estimates were evident. [doi.org]
Objectives In this proof-of-principle study, the effectiveness and safety of transdermal administration of neostigmine/glycopyrrolate to elicit a bowel movement was compared to intravenous administration in patients with spinal cord injury. [nature.com]
For intravenous administration, especially where there is a need for protection against bradycardia, the adult dose is 0.2 mg, or on a weight related basis, 4-5 μg/kg, and 5-10 μg/kg in children. [patents.google.com]
Gastrointestinal
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Delayed Gastric Emptying
gastric emptying, and prolong GI transit time. d Specific Drugs Drug Interaction Comments Amantadine Possible additive anticholinergic effects d Use concomitantly with caution d Antacids Possible decreased absorption of antimuscarinic d Administer oral [drugs.com]
Skin
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Localized Hyperhidrosis
METHODS: Review of case notes in a series of 24 patients, nine with generalized and 15 with localized hyperhidrosis. RESULTS: Fifteen of 19 evaluable patients (79%) responded to oral glycopyrrolate. [ncbi.nlm.nih.gov]
Methods Review of case notes in a series of 24 patients, nine with generalized and 15 with localized hyperhidrosis. Results Fifteen of 19 evaluable patients (79%) responded to oral glycopyrrolate. [doi.org]
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Bromhidrosis
Stamatis Gregoriou, Dimitrios Rigopoulos, Zoe Chiolou, Dafni Papafragkaki, Michalis Makris and George Kontochristopoulos, Treatment of bromhidrosis with a glycine‐soja sterocomplex topical product, Journal of Cosmetic Dermatology, 10, 1, (74-77), (2011 [doi.org]
Neurologic
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Paresthesia
Not only were subjective complaints of tremor, palpitations, and paresthesias increased for metaproterenol, but the heart rate response was significantly elevated (p less than 0.05) compared with glycopyrrolate. [ncbi.nlm.nih.gov]
Treatment
OBJECTIVES: To report a retrospective analysis describing the treatment responses, doses and side-effects of oral glycopyrrolate in the treatment of idiopathic hyperhidrosis. [ncbi.nlm.nih.gov]
Etiology
A concept of the etiology of gastric and duodenal ulcer. Caldwell Lecture, 1955. Am. J. Roentgenol. 75 :219, 1956. Google Scholar 6. Code, C. F. The peptic ulcer problem. Am. J. Digest. Dis. 5 :288, 1960. CrossRef PubMed Google Scholar 7. [link.springer.com]
Chambers et al. presented two case reports and reviewed the etiology, diagnosis, course, and treatment of pregnant patients with myasthenia gravis and who were receiving either neostigmine or pyridostigmine. [5] Plauche presented three case reports and [anesthesiology.pubs.asahq.org]
The usual attempts should be made to determine the etiology of the arrhythmia, and the surgical or anesthetic manipulations necessary to correct parasympathetic imbalance should be performed. [globalrph.com]
Epidemiology
Merello M: Sialorrhoea and drooling in patients with Parkinson's disease: epidemiology and management. Drugs Aging 2008;25:1007-1019 [medicine.uiowa.edu]
Eun Jung Park, Kyung Ream Han, Ho Choi, Do Wan Kim and Chan Kim, An Epidemiological Study of Hyperhidrosis Patients Visiting the Ajou University Hospital Hyperhidrosis Center in Korea, Journal of Korean Medical Science, 10.3346/jkms.2010.25.5.772, 25, [doi.org]
A prospective epidemiologic registry of acyclovir use during pregnancy was established in 1984 and completed in April 1999. Western society has marketed sex via shallow superficiality. [althurayafoundation.org]
Pathophysiology
Author information 1 a Health Sciences Department, Pulmonary Rehabilitation Unit, Fondazione Salvatore Maugeri, Scientific Institute of Milan-IRCCS, Università degli Studi di Milano, Milan, Italy. 2 b Department of Pathophysiology and Transplantation, [ncbi.nlm.nih.gov]
Others have found that clozapine has α 1 - and α 2 -antagonist effects that contribute to sialorrhea. 7, – 9 The pathophysiologic mechanism could be multifactorial, which would explain why CIS is difficult to target and treat. [ajhp.org]
Prevention
The authors recommend glycopyrrolate use to prevent CAS-induced bradycardia and hypotension. [ncbi.nlm.nih.gov]
Anticholinergic drugs do not prevent the liberation of acetylcholine, nor do they react wih acetylcholine. Pharmacokinetics IV Administration: onset of action 2-3 minutes; duration of action 30-60 minutes. [theapms.com]
[…] acetylcholine – Potentially prevent bronchoconstriction. 25. [slideshare.net]