While glycyrrhizin, a sweet-tasting triterpene saponin, is the principal bioactive compound, several bioactive flavonoids and isoflavonoids are also present in the roots of this plant. [ncbi.nlm.nih.gov]

In their presentation to the conference, Indian researchers confirmed that natural compounds in the plant were strong inhibitors of both elevated gastric acid secretion and H. pylori infection. [woman.thenest.com]

The present paper is an effort to highlight the role of a few major constituents of this plant, which have multifaceted pharmacological actions and could be used as templates for designing new pharmacophores using modern chemical and bioanalytical tools [nopr.niscair.res.in]

• Hypertension

  Thus, the relationship of coltsfoot to hypertension is not that it is a hypertensive agent but that in rare cases where liver damage occurs from its excessive use, the damage provokes hypertension (in the one case reported, it was reversible damage). [itmonline.org]

  The most important side effects of licorice and glycyrrhizin are hypertension and hypokalemic-induced secondary disorders. [ncbi.nlm.nih.gov]

  Patients who are diagnosed with hypertension are cautioned by their physicians to keep their blood pressure within acceptable limits. [klemow.wilkes.edu]

  Side-effects are pseudoaldosteronism (which presents as hypernatremia, hypokalemia, hypertension, headache, edema, lethargy, and can lead to congestive heart failure). Deglycyrrhizinated licorice (DGL) is not associated with adverse side effects. [ndhealthfacts.org]

  […] number of dosage forms that include powdered forms, capsules, tablets and liquid extracts.1 Unfortunately, licorice ingestion can lead to excess mineralocorticoid activity that is manifested by suppressed renin levels, sodium retention, hypokalemia, hypertension [ebmconsult.com]

• Enlargement of the Prostate

  Hence this herb is quite good to reduce the size of the prostate gland and also helps to manage the symptoms associated with benign enlargement of the prostate. This herb is packed with anti-microbial activities. [planetayurveda.com]

  It may, therefore, be useful in reducing the growth of the gland and help to prevent some of the symptoms associated with benign enlargement of the prostate. [herbal-supplement-resource.com]

Lymphocytes were treated with 25, 50, and 100 µg/ml G. glabra methanolic root extract alone as well as in combination with MMC (0.1 µg/ml) for 24 and 48 h treatment periods. [ncbi.nlm.nih.gov]

Vamanopaga - herbs that are used in Vamana (emesis) Panchakarma treatment Asthapanopaga - herbs that are used in Basti Panchakarma treatment (rectal enema with decoctions) Kakolyadi, Sarivadi and Anjanadi group of herbs. [planetayurveda.com]

Many preparations were used for treatment of melasma, but none of them was ideal [ 3 ]. [intechopen.com]

Acid Reflux Treatment An herbal formula called Iberogast, containing licorice and numerous other herbs, may help relieve heartburn or symptoms of gastroesophageal reflux disease. [livestrong.com]

This group also had a good prognosis and full recovery was the rule in the majority of cases after cessation of licorice and potassium replacement. [doi.org]

Kaur A, Singh R, Sharma R, Kumar S (2012) Peptic ulcer review on etiology and pathogenesis. International Research journal of pharmacy 3: 34-38. Bethesda (2004) Digestive Diseases Statistics for the United States. U.S. [omicsonline.org]

Description of 3 cases of different etiologies. Minerva Med 79: 55 – 60. Google Scholar | Medline Mattarello, M., Benedini, S., Fiore, C., Camozzi, V., Sartorato, P., Luisetto, G.. ( 2006 ) Effect of licorice on PTH levels in healthy women. [doi.org]

Description of 3 cases of different etiologies. Minerva Med 79 : 55–60 [ PubMed ] [ Google Scholar ] Mattarello M., Benedini S., Fiore C., Camozzi V., Sartorato P., Luisetto G., et al. (2006) Effect of licorice on PTH levels in healthy women. [ncbi.nlm.nih.gov]

However, more epidemiological studies and clinical trials are required for the practical implementation of the plant pharmacotherapy of jaundice. [ncbi.nlm.nih.gov]

The results of the study are published in the American Journal of Epidemiology. [eurekalert.org]

American Journal of Epidemiology. 2009;170(9):1137-1146. This publication is not copyrighted and is in the public domain. Duplication is encouraged. NCCIH has provided this material for your information. [nccih.nih.gov]

Potential health benefits of dietary phytoestrogens: a review of the clinical, epidemiological and mechanistic evidence. J Clin Endocrinol Metab. 1998; 83 2223-2235 64 Theophrastus. [doi.org]

Some of the most important active ingredients were silybin (also recommended by German commission), phyllanthin and andrographolide, whose action leads to bilirubin reduction and normalization of the levels of relevant serum enzymes indicative for the pathophysiological [ncbi.nlm.nih.gov]

Pathophysiology of modulation of local glucocorticoid levels by 11beta-hydroxysteroid dehydrogenases. Trends Endocrinol Metab 2001;12:446-53. Garty H. Mechanisms of aldosterone action in tight epithelia. J Membr Biol 1986;90:193-205. [ebmconsult.com]

Prevent heart disease Recent studies have found that by limiting the damage from LDL ("bad") cholesterol, licorice may discourage artery-clogging plaque formation and contribute to the healthy functioning of the heart. [herbwisdom.com]

American Journal of Preventive Medicine. DOI: 10.1016/j.amepre.2017.01.026 [fda.gov]

Nitrofurantoin and Related Nitrofuram Antibiotics - Prevention or reduction of drug adverse effect; Reduction of gastroirritant side effects of drug (clinically less relevant due to replacement of nitrofurans with ciprofloxacin etc. [ndhealthfacts.org]

This product is not intended to diagnose, treat, cure or prevent any disease. The actual color of liquid extract might be different from the color indicated on the image. [amazon.com]