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Gnathostoma Spinigerum


Presentation

  • We report a case of gnathostomiasis involving a male Thai residing in Kuwait who presented with acute pain in the right iliac fossa. A resection of the terminal ileum and cecum was performed.[ncbi.nlm.nih.gov]
Pharyngitis
  • Setae detect motion (mechanoreceptors), while amphids detect chemicals (chemoreceptors). ( Barnes, 1987 ; Roberts and Janovy, 2000 ) tactile chemical pheromones tactile chemical Food Habits Pharyngeal glands and intestinal epithelium produce digestive[animaldiversity.ummz.umich.edu]
Palpitations
  • The significant symptoms of her illness were migratory joint pain, chest pain, palpitation, and itchy throat, progressively. She has never had swellings.[ncbi.nlm.nih.gov]
Pruritus
  • As human being is not a suitable host for the parasite, ingestion of infected food causes migration of the infective form of the nematode from stomach via intestine to skin, subcutaneous tissue and it is often associated with localized pain, pruritus[ajmhs.org]
  • As human is not a suitable host for the parasite, ingestion of infected fish causes migration of the infective form from stomach via intestine to dermal, subcutaneous tissue and often associated with localized pain, pruritus and erythema.[ncbi.nlm.nih.gov]
Lacrimation
  • A live intraocular nematode was identified from a 37 year-old man presented with iritis, pain, redness, lacrimation, swelling, vision loss and intermittent blindness during many hours per day of the left eye.[ncbi.nlm.nih.gov]
  • A 28 year old female presented with swelling, redness, lacrimation, pain & diminished vision of left eye since 2 1/2 years. Slit lamp examination revealed a worm piercing iris muscle.[casesjournal.biomedcentral.com]
Anterior Uveitis
  • ResultsThe first patient had anterior uveitis, multiple iris holes, and dense vitreous haze with fibrous proliferation over the optic disc. On resolution of the vitreous haze, a live worm was seen in the vitreous cavity.[journals.lww.com]
Suggestibility
  • The results suggest that substances secreted from the esophagus and intestine constitute antigens in excretory-secretory products of the larva.[ncbi.nlm.nih.gov]
Paresis
  • In angiostronglyus infections the clinical syndrome of meningitis was predominant, but one patient, whose angiostrongyliasis was proved serologically, also showed bilateral paresis of abducens nerve.[ncbi.nlm.nih.gov]

Workup

Gnathostoma Spinigerum
  • To describe a patient with isolated monocular optic neuritis caused by an identified Gnathostoma spinigerum infestation.[ncbi.nlm.nih.gov]
  • Gnathostoma spinigerum Owen, 1836 IRMNG_ID 11667348 (urn:lsid:irmng.org:taxname:11667348) Classification Status Rank Parent Fossil range Original description Taxonomic citation IRMNG (2018). Gnathostoma spinigerum Owen, 1836.[irmng.org]
Brugia Malayi
  • The predicted molecular mass of the putative protein was 18.6kDa, and the deduced amino acid sequence had 86, 84.8, 81.3 and 77.2% identity with the CyP of Dirofilaria immitis, Brugia malayi, Onchocerca volvulus and Caenorhabditis elegans, respectively[ncbi.nlm.nih.gov]
Dirofilaria Immitis
  • The predicted molecular mass of the putative protein was 18.6kDa, and the deduced amino acid sequence had 86, 84.8, 81.3 and 77.2% identity with the CyP of Dirofilaria immitis, Brugia malayi, Onchocerca volvulus and Caenorhabditis elegans, respectively[ncbi.nlm.nih.gov]
Tissue Nematode
  • We present a case of eosinophilic meningitis due to the tissue nematode Gnathostoma spinigerum in a patient with remote travel to Korea.[ncbi.nlm.nih.gov]

Treatment

  • His clinical signs and symptoms ameliorated with symptomatic treatment within six months.[ncbi.nlm.nih.gov]

Etiology

  • The etiology of isolated optic neuritis in this patient was Gnathostoma spinigerum which was confirmed by the histopathology of the obtained parasite and the positive serologic test.[ncbi.nlm.nih.gov]
  • Study of the etiological agent of gnathostomosis in Nayarit, Mexico. Parasitol Int. 2002; 51:201–204. PMID: 12113759. [ CrossRef ] [ Google Scholar ] 4. Katchanov J, Sawanyawisuth K, Chotmongkoi V, Nawa Y.[e-sciencecentral.org]
  • Thus, we carried out to know the infection status of Gnathostoma larvae Nematodes of the genus Gnathostoma are clinically important as etiologic agents of foodborne parasitic zoonoses in humans [1].[docksci.com]

Epidemiology

  • The dot-ELISA appears to be a suitable rapid test for diagnostic purpose as well as epidemiological studies.[ncbi.nlm.nih.gov]
  • For the last 20 years, he has focused mostly on the diagnosis, molecular epidemiology, comparative genomics, and ecology of foodborne, waterborne, and zoonotic parasites and is mostly noted for his work on the genus Cryptosporidium .[books.google.es]
  • Main Clinical Presentation in Humans Transmission Morphology Diagnostic Tests and Therapy Epidemiology Public Health and Prevention Strategies Useful Web Links References[web.stanford.edu]
Sex distribution
Age distribution

Pathophysiology

  • In addition, background information on epidemiology, pathogenesis and pathophysiology encourages a fuller understanding of conditions, and over 250 full colour images help with diagnosis when treating patients.[books.google.es]

Prevention

  • To date, albendazole is claimed to be the effective drug in preventing the reoccurrence of migratory swelling in patients.[ncbi.nlm.nih.gov]
  • This up-to-date and essential reference tool, supports all medical professionals in the treatment and prevention of infectious diseases.[books.google.es]

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