We present a case of hepatic bartonellosis in an immunocompetent woman who presented with right upper quadrant pain and a five cm right hepatic lobe mass on CT scan. The patient underwent a right hepatic lobectomy. [ncbi.nlm.nih.gov]

We present a patient with documented granulomatous hepatitis which resolved on liver biopsy 6 weeks after discontinuation of the drug. [jhu.pure.elsevier.com]

• Pain

  and back pain. [medicine.academic.ru]

  This is called referred pain. [huiskopenfrankrijk.eu]

  We present a case of hepatic bartonellosis in an immunocompetent woman who presented with right upper quadrant pain and a five cm right hepatic lobe mass on CT scan. The patient underwent a right hepatic lobectomy. [ncbi.nlm.nih.gov]

  Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis are mild, and others can be serious. [icdlist.com]

  […] title=Idiopathic_granulomatous_hepatitis&oldid=887783048 " Categories : Ailments of unknown cause Abdominal pain Rare diseases Monocyte- and macrophage-related cutaneous conditions Autoimmune diseases Disease stubs Hidden categories: Articles needing [en.wikipedia.org]

• Hodgkin Lymphoma

  […] disease and non Hodgkin's lymphoma Jejunoileal bypass Wegener's granulomatosis Polymyalgia rheumatica Hypogammaglobulinemia Carcinoma [medcosmos.com]

  E.g. in hodgkin lymphoma- diffuse, hypoechoic, small or large nodular lesions in the liver. This will also show the hepatomegaly[6]. [explainmedicine.com]

  Chan, FRCPA: Fibrin ring granuloma Classical Hodgkin lymphoma Trifluoperazine induced liver injury Primary biliary cirrhosis In sarcoidosis Lipogranuloma in nonalcoholic fatty liver disease Back to top [pathologyoutlines.com]

  ’s disease Non-Hodgkin’s lymphoma Renal cell carcinoma Drugs Allopurinol Sulphur drugs Quinidine Other drugs Idiopathic [mja.com.au]

• Malaise

  It also… … Medical dictionary Fever, undulant — An infectious disease due to the bacteria Brucella that characteristically causes rising and falling fevers, sweats, malaise, weakness, anorexia, headache, myalgia (muscle pain) and back pain. [medicine.academic.ru]

  ^len^aWe report a 52 years old male admitted for fever lasting one month, dry cough, headache and malaise. Initial laboratory work up showed an AST of 172 U/l, and ALT of 252 U/l, a GGT of 353 U/l and alkaline phosphatases of 952 U/l. [scielo.conicyt.cl]

  Several adverse events such as generalized symptoms, fever, malaise and fatigue are observed in a significant proportion of patients. [omicsonline.org]

  Fever, malaise, and other systemic symptoms are the usual presenting manifestations of an infective etiology; prolonged FUO is especially common in TB and fungal infections. The history is critical in establishing a drug etiology. [hepatitiscentral.com]

  Symptoms include enlarged liver and spleen, fever fatigue, malaise and an overall crappy feeling all the time. Did the Prednisone thing which only worked on high doses which gave me so many other problems it wasn't worth taking. [forums.prohealth.com]

• Vomiting

  A 58-year-old man experienced episodes of fever, vomiting, and diarrhea over a 2-year period. The laboratory evaluation during these attacks consistently disclosed thrombocytopenia, leukopenia, and elevated liver enzymes. [ncbi.nlm.nih.gov]

  Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis are mild, and others can be serious. [icdlist.com]

  Conclusion Our findings strengthen be oversized so you it was convulsions, weakness i inscrided all the legs, paresthesia, vomiting, facial. [cosl.com.sg]

  Patients usually present with symptoms such as fever, arthralgia, nausea, and vomiting in the month following drug initiation, although the symptoms may be delayed. Physical examination shows the presence of jaundice and hepatomegaly. [jmedicalcasereports.biomedcentral.com]

  || doi: 10.5694/j.1326-5377.2008.tb01564.x Published online: 4 February 2008 Clinical record A 26-year-old recently married Filipino-born woman was referred to our hospital with left upper quadrant pain, vomiting and abnormal liver function test (LFT [mja.com.au]

• Nausea

  Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis are mild, and others can be serious. [icdlist.com]

  Patients usually present with symptoms such as fever, arthralgia, nausea, and vomiting in the month following drug initiation, although the symptoms may be delayed. Physical examination shows the presence of jaundice and hepatomegaly. [jmedicalcasereports.biomedcentral.com]

• Arthritis

  The Best Arthritis Knee Exercise Program. Natural Arthritis Medicine For Joint and Muscle Pain Relief. [huiskopenfrankrijk.eu]

  We describe a patient with rheumatoid arthritis who developed granulomatous hepatitis after taking etanercept. Infectious and metabolic causes of liver disease had been excluded and the liver biopsy was not typical of sarcoidosis. [ncbi.nlm.nih.gov]

  The whole has to anticancer effect by removing to treat lupus, for T cell activation arthritis or pleurisy, which side up. EBP? LIP translation improves. Harvest: Rhizomes are lifted subject to virus diseases, and tingly. Lioydia 41, 166 168. [cosl.com.sg]

  Arthritis Rheumatism 1981; 24 (11): 1414–8. PubMed Neville E, Piyasena KHG, Geraint JD. Granulomas of the liver. Postgrad Med J 1975; 51 : 361–5. PubMed Simon HB, Wolff SM. [gastrohep.com]

• Pruritus

  Ursodeoxycholic acid may help in symptom resolution of pruritus in sarcoidosis and PBC caused by cholestatic jaundice. Ursodeoxycholic acid therapy has been shown to reduce the progression of PBC and results in histologic improvement. [ncbi.nlm.nih.gov]

Assessment of these patients and a comprehensive workup for infectious agents or other causes revealed idiopathic GH confined to the liver in 50%, sarcoidosis with confirmed extrahepatic disease in 22%, drug-related GH in 6%, tuberculosis in 3%, and other [ncbi.nlm.nih.gov]

Owing to the diverse prognostic and therapeutic implications, a detailed workup of all liver biopsies with granulomatous lesions is mandatory. [atmph.org]

Litvinov, bip3{at}georgetown.edu Summary We describe a case of a 23-year-old woman with a history of Crohn's disease (CD), who initially presented with sepsis-like symptoms, subsequently developed severe cholestasis and following extensive inpatient workup [casereports.bmj.com]

• Hepatocellular Carcinoma

  carcinoma, cholangiocarcinoma Systemic disease, e.g. chronic granulomatous disease, Crohn's disease, sarcoidosis, systemic lupus erythematosus, IgG4 disease and other connective tissue disorders Idiopathic: 10 - 15% of all hepatic granulomas; a diagnosis [pathologyoutlines.com]

Intravesical administration of Bacillus Calmette-Guérin is used as a treatment method in superficial bladder cancer. While it is generally well tolerated, serious side effects may develop. [ncbi.nlm.nih.gov]

We conclude that patients with fever of unknown origin who are diagnosed as having idiopathic granulomatous hepatitis have an excellent prognosis, even the minority who require long-term corticosteroids. [ncbi.nlm.nih.gov]

Systemic disease, e.g. chronic granulomatous disease, Crohn's disease, sarcoidosis, systemic lupus erythematosus, IgG4 disease and other connective tissue disorders Idiopathic: 10 - 15% of all hepatic granulomas; a diagnosis of exclusion; excellent prognosis [pathologyoutlines.com]

Prognosis and Treatment Hepatic granulomas of infective or drug etiology regress completely after appropriate therapy. [hepatitiscentral.com]

The benign prognosis of patients with idiopathic hepatic granulomas has been noted previously [ 4,8 ]. [gastrohep.com]

Prognosis Hepatic granulomas caused by drugs or infection regress completely after treatment. Sarcoid granulomas may disappear spontaneously or persist for years, usually without causing clinically important liver disease. [merckmanuals.com]

Hepatic Granulomas Etiology The causes of liver granulomas are legion. [hepatitiscentral.com]

Attempts to define an exact etiology of the granulomatous hepatitis frequently does not yield a precise diagnosis, so that the physician must consider empiric treatment. [ncbi.nlm.nih.gov]

From these tuberculosis & sarcoidosis are the commonest(50%- 65%). 20%- 26% unknown etiology. [explainmedicine.com]

Further epidemiological studies will be necessary to confirm this finding. [ncbi.nlm.nih.gov]

Tuberculosis was considered the most probable cause as per clinico-epidemiological data and antitubercular therapy (ATT) was started but there was poor response. [atmph.org]

Global epidemiology of tuberculosis: morbidity and mortality of a worldwide epidemic. JAMA 1995; 273: 220-6. Sheer TA, Coyle WJ. Gastrointestinal tuberculosis. Curr Gastroenterol Rep 2003; 5: 273-278. [latunisiemedicale.com]

Pathophysiology Granuloma formation is incompletely understood. The lesions are regarded as a host attempt to protect against poorly soluble exogenous or endogenous irritants. [hepatitiscentral.com]

Pathophysiology A granuloma is a localized collection of chronic inflammatory cells with epithelioid cells and giant multinucleated cells. Caseation necrosis or foreign body tissue (eg, schistosome eggs) may be present. [merckmanuals.com]

Objectives: Identify the pathophysiology of granulomatous hepatitis. Describe the appropriate evaluation process for granulomatous hepatitis. Outline the management options for granulomatous hepatitis. [ncbi.nlm.nih.gov]

The pathophysiological mechanism of hemophagocytic syndrome remains poorly understood, but uncontrolled T-lymphocyte activation causes increased Th-1 cytokine secretion promoting macrophage activation. [em-consulte.com]

The pathophysiological mechanism of the liver dysfunction in PMR remains unknown. Although giant cell arteritis is strongly associated with PMR, arteritis has never been reported in the liver biopsy of such a patient. [gastrohep.com]

Prompt diagnosis and appropriate treatment could prevent further complications in the affected patients. [ncbi.nlm.nih.gov]

Vaccines can help prevent some viral forms. [icdlist.com]

Sometimes corticosteroids are used to treat sarcoidosis, but whether they prevent the disorder from progressing is uncertain. NOTE: This is the Consumer Version. [msdmanuals.com]

Patients with progressive hepatic sarcoidosis may benefit from corticosteroid therapy, though it remains unclear whether this prevents hepatic fibrosis; corticosteroids are not indicated for most patients with sarcoidosis and should be given only if TB [hepatitiscentral.com]