Presentation
A 32-year-old woman presented with weight gain, galactorrhea and blurred vision. The MRI showed a cystic, nodular lesion in the intermediate lobe of the pituitary gland and the initial diagnosis was adenoma. [pubmed.ncbi.nlm.nih.gov]
Rosai-Dorfman disease presenting as a pituitary tumor. Clin Endocrinol 1999; 50: 133-137. Kerrison JB, Lee AG. Acute loss of vision during pregnancy due to a suprasellar mass. Survey of Ophtalmology 1997; 41: 402-408. [orbi.uliege.be]
Hypophysitis presented as inflammatory pseudotumor in immunoglobulin G4-related systemic disease Hum Pathol 2007 ; 38 : 1720-1723 [cross-ref] Leporati P., Landek-Salgado M.A., Lupi I., Chiovato L., Caturegli P. [em-select.com]
Neurologic
- Headache
Similar articles Idiopathic granulomatous hypophysitis presenting with galactorrhea, headache, and nausea in a woman: a case report and review of the literature. Sharifi G, Mohajeri-Tehrani MR, Navabakhsh B, Larijani B, Valeh T. Sharifi G, et al. [pubmed.ncbi.nlm.nih.gov]
Workup
Serum
- Hyperprolactinemia
Clinically, lymphocytic hypophysitis can manifest with compression symptoms, hypopituitarism, diabetes insipidus or hyperprolactinemia. The imaging technique of choice is magnetic resonance imaging, which helps to characterize the sellar lesion. [pesquisa.bvsalud.org]
Treatment
Treatment includes replacement of the functional pituitary deficiency and the use of corticosteroids, generally at high doses. Surgical treatment is reserved for patients unresponsive to conservative therapy. [pesquisa.bvsalud.org]
After two months of corticoid treatment, dyplopia disappeared. [revistaneurocirugia.com]
In this chapter, we shall consider these different pathologies as well as the specific treatment of lymphocytic hypophysitis. [orbi.uliege.be]
Etiology
Granulomatous hypophysitis can be of known etiology, whether infectious (currently highly infrequent) or non-infectious (ruptured Rathke's cyst, etc.). [pesquisa.bvsalud.org]