We describe a 53-year-old male thymoma patient who presented with respiratory symptoms caused by granulomatous lung disease and an opportunistic infection. [ncbi.nlm.nih.gov]

[…] diarrhea, and anal fissures before presenting to a physician. [journals.lww.com]

• Mediastinal Lymphadenopathy

  Biopsy of the nodular chest lesions or mediastinal lymphadenopathies were performed in 8 patients, and revealed typical rheumatoid nodules in 4 cases and noncaseating granulomatous lesions in 4 cases. [ncbi.nlm.nih.gov]

  A CT scan with contrast was performed to evaluate for mediastinal lymphadenopathy. [journals.lww.com]

• Malaise

  […] and main bronchi resulting from fibrosis -Steroids and immunosuppression -Common spontaneous remission -Overall good prognosis -Relapses occur Hypersensitivity pneumonitis (HP) -Acute: responds to steroids -Sx include cough, fever, chest tightness, malaise [brainscape.com]

  […] of presumed Crohn’s disease at age 16 years, on the basis of peri-anal fistula with compatible histopathological features and spontaneous healing without medical intervention, presented to our facility with a 10-day history of fever (39 C to 40 C), malaise [jmedicalcasereports.biomedcentral.com]

• Pulmonary Disorder

  Chronic airflow limitation has the highest morbidity rate of any significant chronic pulmonary disorder in the United States and is the second most common cause of hospital admissions. [medical-dictionary.thefreedictionary.com]

  View Article Google Scholar Fairfax AJ, Haslam PL, Pavia D, Sheahan NF, Bateman JR, Agnew JE, Clarke SW, Turner-Warwick M: Pulmonary disorders associated with Sjögren’s syndrome. Q J Med. 1981, 50: 279-295. [jmedicalcasereports.biomedcentral.com]

At that point, the patient was admitted to the hospital for further workup. [journals.lww.com]

• Mediastinal Mass

  It is classified as a primary immunodeficiency 1), and patients usually present with recurrent infections or a mediastinal mass 2). [kjim.org]

• Microcytic Anemia

  However, the patient did have a hypochromic microcytic anemia with a hemoglobin concentration of 7.3 g/dL, a hematocrit of 27.5% with a low mean corpuscular volume of 63.5 mm 3, a low mean corpuscular hemoglobin concentration of 26.7 g/dL, and a red blood [journals.lww.com]

• Ejection Fraction Decreased

  Between 2013 and 2015, echocardiograms and chest magnetic resonance imaging showed severe cardiomyopathy with the ejection fraction decreasing from 70% to 35% and evidence of non-ischemic type fibrosis of the lower and posterior ventricular wall, as well [synapse.koreamed.org]

Outcome was favorable for all the patients, with either discontinuation or maintenance of anti-TNF-alpha treatment. [ncbi.nlm.nih.gov]

The disease is known to affect people of all age groups and while around 40% patients respond well to treatment, over 40% develop anatomical problems and long-term pulmonary complications. [buzzle.com]

[…] adenopathy most common finding -Upper and mid lung shows coarse reticular and cystic changes and volume loss, upward displacement of the hila and main bronchi resulting from fibrosis -Steroids and immunosuppression -Common spontaneous remission -Overall good prognosis [brainscape.com]

Featured 6,735 Community 48 Act Your Age When It Comes to Skin Care Act Your Age When It Comes to Skin Care Cancer Connect 7 hrs Cyramza Improves Survival in Poor-Prognosis Liver Cancer Cyramza Improves Survival in Poor-Prognosis Liver Cancer Cancer Connect [news.cancerconnect.com]

Prognosis The prognosis has greatly improved with the use of antibacterial and antifungal prophylaxis therapy, with most patients living well into adulthood. The documents contained in this web site are presented for information purposes only. [orpha.net]

Patients with absent NADPH oxidase activity and poor prognosis have been recommended for early HSCT. [emedicine.medscape.com]

Determining the specific type of interstitial lung disease is essential in order to predict prognosis and outline appropriate therapies. [utswmedicine.org]

Abstract Granulomatous lung diseases, such as sarcoidosis, hypersensitivity pneumonitis, Wegener's granulomatosis, and chronic beryllium disease, along with granulomatous diseases of known infectious etiologies, such as tuberculosis, are major causes [ncbi.nlm.nih.gov]

other autoimmune Hx for granulomatous lung disease -Travel: bakersfield associated w/ coccidiomycosis -Occupation: farms usually associated w/ fungi and/or hypersensitivity -Pigeons: hypersensitivity -Multisystem granulomatous disease w/ no known etiology [brainscape.com]

Unlike most pathology textbooks, diseases are grouped on the basis of pathologic findings rather than etiology, mirroring the actual practice of surgical pathology. [books.google.com]

Etiology Infection Atypical Mycobacteria Brucellosis (see Brucellosis, [[Brucellosis]]) Coccidioidomycosis (see Coccidioidomycosis, [[Coccidioidomycosis]]) Histoplasmosis (see Histoplasmosis, [[Histoplasmosis]]) Leishmaniasis (see Leishmaniasis, [[Leishmaniasis [mdnxs.com]

This project will also characterize the potential etiologic roles of reproducibly associated sarcoidosis risk variants by examining important smoking exposure and disease severity subgroups to determine whether disease risk depends on smoking history [grantome.com]

This article reviews the epidemiologic, clinical, pathologic, and radiologic features of sarcoidosis, hypersensitivity pneumonitis, berylliosis, and the five entities traditionally classified as pulmonary angiitis and granulomatosis. [ncbi.nlm.nih.gov]

[…] largest cause of a death from a single pathogen TB kills twice as many adults as AIDS, malaria and other parasitic diseases combined 80% of TB toll in developing countries is in the economically most productive age-group (15-60 years) TUBERCULOSIS - Epidemiology [slideplayer.com]

Summary Epidemiology The average worldwide birth prevalence is estimated at 1/ 217,000. Clinical description CGD can present at any age but is most commonly diagnosed before the age of 5 years. [orpha.net]

Primary prevention of this disease relies on ventilation and good use practices. Secondary prevention of this disease requires education of both the general public and clinicians to allow for the early diagnosis of this disease. [ncbi.nlm.nih.gov]

الصفحة 158 - Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary. ‏ [books.google.com]

The results of this study should provide important genes or regions for follow-up fine-mapping and functional studies that should ultimately provide better prevention and treatment targets for development. [grantome.com]

Cancer Connect 3 days Overview of Melanoma Melanoma: Signs & Symptoms, Diagnosis, Screening, Prevention & Early Detection Cancer Connect 3 days Sunscreen May Reduce Risk of Melanoma Regular use of sunscreen may help prevent melanoma. [news.cancerconnect.com]

Prevention Since CGD is a hereditary disorder, it cannot currently be prevented. Patients and their families may benefit from genetic counseling. [medical-dictionary.thefreedictionary.com]