The clinical and pathological aspects of the 20 cases of GSS reported in the recent literature are reviewed and compared with those of the present case. [ncbi.nlm.nih.gov]

• Inguinal Lesions

  The inguinal lesions progressively enlarged to become bulky pendulous tumors Pathology Skin biopsy reveals a patchy lichenoid and nodular infiltrate of lymphocytes extending from the superficial dermis to the subcutaneous fat and even to the skeletal [plasticsurgerykey.com]

• Persistent Cough

  The patient also developed a persistent cough and worsening exertional dyspnea five years after her diagnosis. [omicsonline.org]

• Abdominal Mass

  Histologic examination of a specimen from the abdominal mass revealed an extensive lymphoid infiltrate with scattered multinucleated giant cells extending from the papillary dermis to the subcutis. [ncbi.nlm.nih.gov]

• Cardiomegaly

  Repeat CT of the chest showed progression of ground-glass opacities in the right lung apex, chronic multilobar bronchiectasis with cicatrization atelectasis, cardiomegaly and dilated pulmonary artery compatible with pulmonary hypertension. [omicsonline.org]

Further invasive workup such as additional lung biopsies or bronchoscopic studies was not pursued because the previous studies were unremarkable. [omicsonline.org]

• Atelectasis

  Repeat CT of the chest showed progression of ground-glass opacities in the right lung apex, chronic multilobar bronchiectasis with cicatrization atelectasis, cardiomegaly and dilated pulmonary artery compatible with pulmonary hypertension. [omicsonline.org]

• Foam Cell

  It was composed mainly of numerous histiocytes and many multinucleate cells and foam cells. The case has the clinical and microscopic features of granulomatous slack skin (GSS), which may be considered to be a peculiar form of localized elastolysis. [ncbi.nlm.nih.gov]

Stable or progressive disease was observed in most patients despite various treatment modalities. [ncbi.nlm.nih.gov]

prognosis is usually excellent with appropriate therapy. [dovemed.com]

The prognosis of GMF appears worse than that of classic nongranulomatous mycosis fungoides. [ncbi.nlm.nih.gov]

This article reviews its literature on the etiology, clinical findings, and treatment of Granulomatous Slack Skin Disease. [ncbi.nlm.nih.gov]

McKee's Pathology of the Skin is the most complete, in-depth resource on dermatopathology, covering etiology, pathogenesis, disease mechanisms, and recent genetic, molecular, and basic science data. Drs. J. [books.google.com]

Other possible etiologies that may contribute to the patient’s pulmonary findings include radiation induced lung disease given her multiple radiation treatments, reactive granulomatous conditions, cryptogenic infection, and sarcoid-lymphoma-syndrome. [omicsonline.org]

The exact etiology of this condition is presently unknown. A chromosomal translocation involving t (3;9) (q12; p24) has been described. The rearrangement of T-beta cell receptor gene is seen in molecular analysis. [ijdvl.com]

[…] a good term since nonspecific as to histological type) Epidemiology Most common type of cutaneous T cell lymphoma, almost 50% of all primary cutaneous lymphomas Adults / elderly but also children and adolescents M:F ratio 2:1, black:white ratio 1.7 Etiology [pathologyoutlines.com]

Data from cancer registries of the Surveillance, Epidemiology, and End Results (SEER) Program found the incidence of MF to be 0.64 per 100,000 person years, with a median age at diagnosis of 55 to 60 years. 1-3 The incidence of MF/Sezary syndrome (SS) [jddonline.com]

(effective October 01, 2015) Signs and Symptoms Itchy, painful, peeling and reddened skin Ulcerated skin lesion s, which may become infected Diagnostic Exams Flow cytometry Immunophenotyping Peripheral blood smear Progression and Transformation None Epidemiology [seer.cancer.gov]

1814), because it resembles yaws (caused by Treponema), which is also called pian Later renamed as mycosis fungoides, due to its resemblence to mushrooms Also called cutaneous T cell lymphoma (not a good term since nonspecific as to histological type) Epidemiology [pathologyoutlines.com]

Epidemiology [ 3 ] CTCLs typically affect adults with a median age of 55-60 years; the annual incidence is about 0.5 per 100,000. [patient.info]

Despite the indolent behavior of granulomatous slack skin, its early recognition and continuous monitoring by a dermatologist becomes essential for its management and prevention of an unfavorable outcome. [ncbi.nlm.nih.gov]

The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer. [gulfdoctor.net]

How can Granulomatous Slack Skin be Prevented? The cause of Granulomatous Slack Skin is unknown, and hence, there are no known methods to prevent its occurrence. However, the following factors may be considered to reduce risk of GSS. [dovemed.com]

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]