We present a rare case of probable DRESS secondary to griseofulvin. 2016 Wiley Periodicals, Inc. [ncbi.nlm.nih.gov]

• Cervical Lymphadenopathy

  Abstract A 9-year-old boy presented with fever, rash, anterior cervical lymphadenopathy, high liver enzymes, atypical lymphocytosis, and eosinophilia (drug reaction with eosinophilia and systemic symptoms [DRESS]). [ncbi.nlm.nih.gov]

• Fatigue

  There have also been reports of dizziness and fatigue. Women can experience problems with their monthly menstrual cycle if they have a reaction to this medication. [brighthub.com]

  Nervous system disturbance: Blurred vision, dizziness, depression, nightmares, fatigue. Menstrual disturbance. Liver disturbance. Griseofulvin should not be taken in pregnancy as there is a slight risk of malformation of the fetus. [dermnetnz.org]

  Side Effects of Griseofulvin Common side effects include: oral thrush nausea vomiting diarrhea headache fatigue dizziness insomnia mental confusion impairment of performance of routine activities This is not a complete list of griseofulvin side effects [rxwiki.com]

  Other adverse reactions include headache, dizziness, fatigue, insomnia, photosensitivity, nausea, vomiting, confusion, leukopenia, proteinuria, oral candidiasis, nephrosis, gastrointestinal bleeding and diarrhea. [aocd.org]

• Acute Intermittent Porphyria

  intermittent porphyria Proper Use of This Medicine Griseofulvin is best taken with or after meals, especially fatty ones (for example, whole milk or ice cream). [mold-survivor.com]

  This may precipitate an attack of acute intermittent porphyria in susceptible patients. Pregnancy Due to possible teratogenic and abortifacient effects, use of griseofulvin during pregnancy is contraindicated. [pdr.net]

• Intravenous Administration

  Furthermore, this analogue proved compatible with formulations suitable for both oral and intravenous administration. Finally, 2'-benzylamine analogue 10 was confirmed to induce G2/M cell cycle arrest in vitro. Copyright 2017 Elsevier Masson SAS. [ncbi.nlm.nih.gov]

• Nausea

  Griseofulvin interacts with alcohol rather like disulfiram (Antabuse) and can cause severe nausea and vomiting. [dermnetnz.org]

  Common side effects may include: nausea, vomiting, upset stomach, diarrhea; headache, tired feeling; sleep problems (insomnia); or itching, rash. This is not a complete list of side effects and others may occur. [rxlist.com]

  Common side effects include flushing, nausea, vomiting, and diarrhea. Griseofulvin may cause dizziness. Do not drive or operate heavy machinery until you know how it affects you. [rxwiki.com]

• Abdominal Pain

  New chapters cover common exanthems of childhood, acne, cardiac murmur evaluation, gastrointestinal parasites, gastroesophageal reflux disease, acute abdominal pain, diabetes, and vision and hearing abnormalities. [books.google.de]

  Tell your doctor right away if any of these rare but very serious side effects occur: yellowing eyes / skin, stomach / abdominal pain, persistent nausea / vomiting, dark urine, signs of kidney problems (such as change in the amount of urine, frothy urine [webmd.com]

  pains and mental disorder) have systemic lupus erythematosus (a disorder which causes the immune system to attack the body). [drugs.com]

• Leg Pain

  A previously healthy 5-year-old boy presented with tactile fever, rash on his legs and back, swelling of his toes and fingers, and leg pain. He was being treated at the time with griseofulvin for tinea capitis. [ncbi.nlm.nih.gov]

• Skin Rash

  Skin rashes disappeared after discontinuation of griseofulvin and recurred on challenge with the drug. [ncbi.nlm.nih.gov]

  Side effects that you should report to your doctor or health care professional as soon as possible: allergic reactions like skin rash or hives, swelling of the face, lips, or tongue confusion dark urine fever or infection loss of appetite mouth sores, [carefirst.staywellsolutionsonline.com]

  Read the entire detailed patient monograph for Grifulvin V (Griseofulvin Microsize) Grifulvin V Professional Information SIDE EFFECTS When adverse reactions occur, they are most commonly of the hypersensitivity type such as skin rashes, urticaria and [rxlist.com]

• Eczema

  Rosacea, Acne, Shingles: Common Adult Skin Diseases Learn to spot and treat skin conditions commonly found in adults such as acne, eczema, shingles, psoriasis, rosacea, hives, cold... [medicinenet.com]

  For example, tinea corporis can be confused with eczema, tinea capitis can be confused with alopecia areata, and onychomycosis can be confused with dystrophic toe-nails from repeated low-level trauma. [aafp.org]

  CUTANEOUS T-CELL LYMPHOMA Cutaneous T-cell lymphoma is a rare type of non-Hodgkin's lymphoma in which certain white blood cells called T-lymphocytes become cancerous and affect the skin. 1 Because CTCL can look like common skin diseases such as psoriasis, eczema [stockwatch.com]

• Hematuria

  We describe a patient with hematuria, pyuria, eosinophiluria, decreased renal function, and severe anemia that developed while she was receiving chronic therapy with griseofulvin for onychomycosis. [ncbi.nlm.nih.gov]

• Headache

  All patients did, however, report mild, transient gastrointestinal discomfort during the first 2 days of therapy, and one patient mentioned a mild headache. These remitted after approximately 2 to 4 days. [ncbi.nlm.nih.gov]

  Common side effects may include: nausea, vomiting, upset stomach, diarrhea; headache, tired feeling; sleep problems (insomnia); or itching, rash. This is not a complete list of side effects and others may occur. [rxlist.com]

However, on laboratory workup, complement levels are normal. Management of serum sickness-like reaction includes replacing the offending agent and providing symptomatic relief. [ncbi.nlm.nih.gov]

• Pyuria

  We describe a patient with hematuria, pyuria, eosinophiluria, decreased renal function, and severe anemia that developed while she was receiving chronic therapy with griseofulvin for onychomycosis. [ncbi.nlm.nih.gov]

However, the optimal treatment duration for its use in the treatment of tinea capitis caused by Microsporum species has not yet been determined. [ncbi.nlm.nih.gov]

We studied 153 consecutive patients of tinea capitis for clinical patterns, causative dermatophytic species, clinico-etiological correlation, and response to griseofulvin. Culture and sensitivity were done on all patients. [ncbi.nlm.nih.gov]

However, varying dosage schedules, changes in epidemiology, and rising drug resistance are factors that hamper treatment in some cases. [ncbi.nlm.nih.gov]

Epidemiology and treatment of tinea capitis: ketoconazole vs. griseofulvin. Pediatr Infect Dis J. 1987; 6(1):46–49. 11. Ginsburg CM, Gan VN, Petruska M. [aafp.org]

Over the past 30 years, the reported incidence of tinea capitis has increased significantly, as travel and migration have been associated with changes in epidemiology and in distribution of the species of fungi that are likely to cause tinea capitis [doi.org]

In conclusion, we postulate that DXA acid would be more effective to prevent liver damage induced by Gris. [ncbi.nlm.nih.gov]

(via antibiotic antifungal agent ) Application (s): antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. [ebi.ac.uk]

Give with food to prevent GI distress. Store in closed containers away from light. Prevent further reinfection by cleaning disinfecting cage and cage articles. Clip nails to prevent secondary infections. [ratguide.com]

It doesn't kill fungal infections that are established in these areas, but instead prevents fungal cells from infecting new keratin that grows. It does this by preventing fungal cells from growing and multiplying. [netdoctor.co.uk]