Presentation
This mini review presents a personal view about the past, the present and the future of the relationship between growth retardation and the IGF system. [ncbi.nlm.nih.gov]
Entire Body System
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Atrial Septal Defect
The patient also presents with ventricular and atrial septal defects, hypoplastic mitral valve, persistent left superior vena cava, accessory spleen, and club foot. [ncbi.nlm.nih.gov]
Eyes
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Aniridia
We report on two siblings with an unusual constellation of congenital anomalies comprising 46,XY disorder of sex development (DSD), congenital adrenal hypoplasia, aniridia, dysmorphic facial features, intrauterine growth retardation, and minor skeletal [ncbi.nlm.nih.gov]
Musculoskeletal
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Anterior Knee Pain
Osteochondrosis of the primary ossification centre of the patella (Köhler's disease) has been reported as a rare cause of anterior knee pain in children between 5 and 9 years of age. The aetiology remains unclear. [ncbi.nlm.nih.gov]
Face, Head & Neck
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Bulbous Nose
A 1-year-old boy, presenting with hypotonia, blepharophimosis, ptosis, a bulbous nose, mild psychomotor retardation, and epilepsy, was found to have mosaicism of chromosome ring 14 and monosomy 14. [ncbi.nlm.nih.gov]
Workup
Other Pathologies
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White Matter Lesions
We report on a patient with congenital distal limb contractures, characteristic face, prominent metopic sutures, narrow forehead, severe psychomotor and growth retardation, white matter lesions and failure to thrive. [ncbi.nlm.nih.gov]
Treatment
The test was positive, and the patient was started empirically on treatment to which he responded and ultimately recovered fully. Gastrectomy was not performed, and following treatment, the ulcer, anemia, and poor growth resolved. [ncbi.nlm.nih.gov]
If despite these measures, growth suppression still occurs then treatment with medicines other than corticosteroids should be considered. [medsafe.govt.nz]
Prognosis
Intracranial germinoma is a rare malignant tumour in childhood with an excellent prognosis under adequate therapy. [ncbi.nlm.nih.gov]
In such cases, the prognosis is good Additional and Relevant Useful Information for Intrauterine Growth Retardation: There are about 200,000 cases of Intrauterine Growth Retardation in the United States annually. [dovemed.com]
IUGR Prognosis AAFP suggests that most infants with IUGR have a positive prognosis, with many catching up in growth within the first three months after birth. [birthinjuryguide.org]
Because IUGR has so many causes, the long-term prognosis for affected infants varies tremendously. [latimes.com]
Etiology
We propose etiology and the term pyloric achalasia for this late-onset functional gastric outlet obstruction. [ncbi.nlm.nih.gov]
The etiology and perinatal behaviour in the two groups were also different. A single head: abdominal circumference ratio may be useful in differentiating between symmetrical and asymmetrical IUGR after 36 weeks. [link.springer.com]
A more specific threshold would be one oriented on the 5th percentile - however, a number of endangered infants would eventually be overlooked then. 3 Etiology Causes can be genetic or due to environmental factors. [flexikon.doccheck.com]
Etiology Many different factors cause IUGR, but they may be divided into two large categories, based on etiology. These categories include fetoplacental factors and maternal factors. [aafp.org]
Epidemiology
The aim of this review is to study the epidemiology, physiopathology and possible causes of IUGR. Also, it intends to study the possible role of the placenta as an IGF-1 target organ. [ncbi.nlm.nih.gov]
Clin Chem 1966 ; 12 : 47 – 57. 20 Rapid evaluation of malaria parasite density and standardization of thick smear examination for epidemiological investigations. [ajcn.nutrition.org]
infarction and abruption) Epidemiology risk factors asymmetric IUGR chronic hypertension pre-eclampsia chronic renal failure diabetes smoking symmetric intrauterine infections chromosomal abnormalities congenital anomalies Pathophysiology asymmetric [step2.medbullets.com]
Malin Hult, Niklas Darin, Ulrika Döbeln and Jan‐Eric Månsson, Epidemiology of lysosomal storage diseases in Sweden, Acta Paediatrica, 103, 12, (1258-1263), (2014). Bryan G. [dx.doi.org]
Epidemiology Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Pathophysiology
infarction and abruption) Epidemiology risk factors asymmetric IUGR chronic hypertension pre-eclampsia chronic renal failure diabetes smoking symmetric intrauterine infections chromosomal abnormalities congenital anomalies Pathophysiology asymmetric [step2.medbullets.com]
[…] abnormalities chemical exposure constitutional small size However, there is an increasing sentiment that this classification may not be ideal, and that comparison of blood flow via ultrasound dopplers ( see below ) may provide more helpful return to top Pathophysiology [sharinginhealth.ca]
References:[3][1][4] Pathophysiology Caused by extrinsic factors, which affect the fetus in the later stages of gestation (i.e., third trimester). [amboss.com]
It has helped physicians understand the pathophysiology of IUGR with regard to diminished blood flow. [aafp.org]
Prevention
Severe nutritional Cbl deficiency is an important nutritional disease where complications can be prevented with early treatment. [ncbi.nlm.nih.gov]
IUGR Prevention Unfortunately, there is currently no known way that will prevent IUGR, but there are certain steps that you can to help reduce the risk, including: Eating healthy and taking appropriate prenatal vitamins Not smoking or partaking in drug [birthinjuryguide.org]
Therefore, a preventive management approach needs to be instituted in developing countries and this should begin with the first antenatal clinic visit. [ijponline.biomedcentral.com]