All contained SLCT or Sertoli cell tumour components. aGCT and jGCT components were identified in seven and 10 cases, respectively, with one presenting both components. [ncbi.nlm.nih.gov]

• Hunting

  Chivukula, M, Hunt, J, Carter, G, Kelley, J, Patel, M, Kanbour-Shakir, A. Recurrent gynandroblastoma of ovary—a case report: a molecular and immunohistochemical analysis. Int J Gynecol Pathol. 2007 ;26: 30 - 33. [journals.sagepub.com]

  ^ Chivukula M, Hunt J, Carter G, Kelley J, Patel M, Kanbour-Shakir A (January 2007). "Recurrent gynandroblastoma of ovary-A case report: a molecular and immunohistochemical analysis". Int. J. Gynecol. [dictionnaire.sensagent.leparisien.fr]

  ^ Chivukula, Mamatha; Hunt, Jennifer; Carter, Gloria; Kelley, Joseph; Patel, Minita; Kanbour-Shakir, Amal (2007). "Recurrent Gynandroblastoma of Ovary-A Case Report". [en.wikipedia.org]

• Abdominal Mass

  Gynandroblastoma usually presents clinically as an abdominal mass, often associated with either virilizing or feminizing manifestations. [ncbi.nlm.nih.gov]

• Hirsutism

  A 66-year-old woman without metrorrhagia or hirsutism presented with abdominal pain and slightly elevated serum estradiol levels. [ncbi.nlm.nih.gov]

  Case Report A 32-year-old gravida 0 woman presented with hirsutism, oligomenorrhea, and morbid obesity with a body mass index of 37 kg/m2. Family history was negative for known genetic syndromes, including Von Hippel–Lindau and Lynch syndromes. [docksci.com]

  It typically secretes androgens, and as a result women with this tumour often present with new onset of hirsutism or virilisation. Leydig cell tumour. [dictionnaire.sensagent.leparisien.fr]

  SLCT frequently presents with signs of virilisation (hirsutism, voice changes), along with typical features of an ovarian neoplasm, including abdominal distension and pain. PMID: 21205968, 21501861, 25844550, 27858560. [dicer1syndrome.ca]

  At most of patients the hirsutism of various degree is observed (see the Hirsutism). Complaints to abdominal pains are absent, a uterus almost always infantile. [bigmed.info]

• Vaginal Bleeding

  An 18-year-old adolescent experienced intermittent vaginal bleeding. A year later, a right adnexal mass with a heterogeneous imaging appearance was identified. Laparoendoscopic single-site ovarian tumorectomy was performed. [ncbi.nlm.nih.gov]

  CASE An 18-year-old adolescent experienced intermittent vaginal bleeding. A year later, a right adnexal mass with a heterogeneous imaging appearance was identified. Laparoendoscopic single-site ovarian tumorectomy was performed. [semanticscholar.org]

  In both groups, the vaginal bleeding is due to oestrogen secreted by the tumour. In older women, treatment is total abdominal hysterectomy and removal of both ovaries. [dictionnaire.sensagent.leparisien.fr]

• Oligomenorrhea

  She had no history of symptoms associated with endocrine manifestations, i.e., neither estrogenic nor androgenic changes, such as endometrial hyperplasia, abnormal endometrial bleeding, oligomenorrhea, infertility, or virilization. [jpatholtm.org]

  Case Report A 32-year-old gravida 0 woman presented with hirsutism, oligomenorrhea, and morbid obesity with a body mass index of 37 kg/m2. Family history was negative for known genetic syndromes, including Von Hippel–Lindau and Lynch syndromes. [docksci.com]

  Only at one patient the signs indicating androgenic activity (a hirsutism and an oligomenorrhea) are noted. [bigmed.info]

  Fewer than 5% of the patients are younger than the age of normal puberty, and approximately three quarters of these children exhibit isosexual pseudoprecocity. 4 In adult patients, menstrual disturbances such as menometrorrhagia, oligomenorrhea, and amenorrhea [glowm.com]

  […] studies. [72] The well-differentiated tumors occur at an average age of 35 years and retiform tumors at an average age of 15 years. [44] Clinical features About one third of patients with Sertoli-Leydig cell tumor have androgenic manifestations including: oligomenorrhea [emedicine.medscape.com]

• Primary Amenorrhea

  […] ultrastructure. ( 6284338 ) 1982 27 Hormone studies in a gynandroblastoma. ( 658481 ) 1978 28 Gynandroblastoma of the ovary. ( 1169960 ) 1975 29 Gynandroblastoma of the ovary. ( 4846779 ) Devi N.N....Nair M.B. 1974 30 Ovarian gynandroblastoma presenting with primary [malacards.org]

  At persons 15 years, as a rule, are more senior primary amenorrhea is noted; only at a part of patients the secondary amenorrhea or an oligomenorrhea are observed; Shereshevsky's syndrome — Turner (see Turner a syndrome) is found seldom. [bigmed.info]

The present findings can help clinicians make an accurate preoperative imaging diagnosis of gynandroblastoma with a juvenile granulosa cell component and plan an adequate treatment strategy for this rare, potentially malignant neoplasm. [ijrcog.org]

Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. [books.google.com]

The diagnosis and treatment for patients with gynandroblastoma is also discussed. [ncbi.nlm.nih.gov]

The prognosis is favorable and similar to that of the individual tumor components, but clinical follow-up in the small number of cases has been limited. [ncbi.nlm.nih.gov]

The prognosis is favorable and similar to that of the individual tumor components, but clinical follow-up in the small number of cases has been limited. ©1997International Society of Gynecological Pathologists [journals.lww.com]

Diagnosis - Gynandroblastoma * Colon & Rectal Cancer: Home Testing - Home Colorectal Cancer Tests - Home Fecal Occult Bleeding Tests Prognosis - Gynandroblastoma Not supplied. Treatment - Gynandroblastoma Not supplied. [checkorphan.org]

[…] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]

The neoplasm occurs mainly during the first 3 decades of life. [1] Etiology The etiology of JGCT is unknown. [emedicine.medscape.com]

Etiology There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder [atlasgeneticsoncology.org]

Because the etiology of a disease is not clear yet, there is no standard scheme of treatment. A number of gynecologists recommend to carry out hormonal treatment in the cyclic mode or treatment by gonadotrophins according to the standard scheme. [bigmed.info]

English : BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

FOLLOW UP RECOMMENDATIONS Physical exam every 3 months for the first 2 years after diagnosis, every 6 months until 5 years, and then annually thereafter If CA-125 elevated... 1 Beral V, Doll R, Hermon C, et al; and Collaborative Group on Epidemiological [5minuteconsult.com]

Cancer standardized incidence ratios were determined relative to the Surveillance, Epidemiology, and End Results (SEER) program (which does not capture all DICER1 -associated neoplasms). [ascopost.com]

Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors. [emedicine.medscape.com]

Prevention - Gynandroblastoma Not supplied. Diagnosis - Gynandroblastoma * Colon & Rectal Cancer: Home Testing - Home Colorectal Cancer Tests - Home Fecal Occult Bleeding Tests Prognosis - Gynandroblastoma Not supplied. [checkorphan.org]

[…] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention [decs.bvs.br]

Clinical prevention of tumors of ovaries is based hl. obr. on early detection and treatment of pretumor diseases. The large role in it is played by annual routine maintenances. [bigmed.info]