A left ovarian gynandroblastoma in a 24-year-old woman was clinically manifest by prolonged (7 years) amenorrheas interrupted by metrorrhagies, with moderate hypertrichosis is presented. [ncbi.nlm.nih.gov]

• Virilization

  The hormonal data obtained do not account for the marked virilization observed. [ncbi.nlm.nih.gov]

  Gynandroblastoma usually presents clinically as an abdominal mass, often associated with either virilizing or feminizing manifestations. [journals.lww.com]

• Swelling

  Any swelling or tumefaction. 2. SYN: neoplasm. 3. One of the four signs of inflammation (t., calor, dolor, rubor) enunciated by Celsus. [medicine.academic.ru]

  Besides swelling and enlargement of the clitoris, other symptoms include vomiting, hypertension, and early pubic hair in childhood. 2. Gynandroblastoma Gynandroblastoma is a type of hormonal cancer that affects the ovaries. [en.amerikanki.com]

  Occasionally, swelling, tenderness, and discharge from the breasts are prominent. Vaginal cytology typically shows increased maturation of squamous epithelial cells. [clinicalgate.com]

  When JGCT occurs after puberty, patients usually present with abdominal pain, swelling, menstrual irregularities, or amenorrhea. [emedicine.medscape.com]

• Abdominal Mass

  Gynandroblastoma usually presents clinically as an abdominal mass, often associated with either virilizing or feminizing manifestations. [ncbi.nlm.nih.gov]

• Pelvic Mass

  Physical examination disclosed a painless pelvic mass measuring 20 cm across with normal secondary sex characteristics, and no signs of virilisation. [ncbi.nlm.nih.gov]

  mass * Enlarged abdomen * Male-pattern hair growth in females * Small breast Causes - Gynandroblastoma Not supplied. [checkorphan.org]

  An 61-year-old woman, menopausic, consulted for an abdominal pelvic mass. a latero-uterine mass measuring 27.8 cm in diameter showed a predominantly cystic pattern with a partial solid component. A unilateral adnexectomy was performed. [ijrcog.org]

  Although AGCTs are mostly estrogenic, very rare cases, usually large thin-walled cystic tumors, are associated with androgenic manifestations. 13 In addition to endocrine symptoms, patients with AGCTs have signs and symptoms related to a pelvic mass such [clinicalgate.com]

• Hirsutism

  A 66-year-old woman without metrorrhagia or hirsutism presented with abdominal pain and slightly elevated serum estradiol levels. [ncbi.nlm.nih.gov]

  Case Report A 32-year-old gravida 0 woman presented with hirsutism, oligomenorrhea, and morbid obesity with a body mass index of 37 kg/m2. Family history was negative for known genetic syndromes, including Von Hippel–Lindau and Lynch syndromes. [docksci.com]

  It typically secretes androgens, and as a result women with this tumour often present with new onset of hirsutism or virilisation. Leydig cell tumour. [dictionnaire.sensagent.leparisien.fr]

  SLCT frequently presents with signs of virilisation (hirsutism, voice changes), along with typical features of an ovarian neoplasm, including abdominal distension and pain. PMID: 21205968, 21501861, 25844550, 27858560. [dicer1syndrome.ca]

  At most of patients the hirsutism of various degree is observed (see the Hirsutism). Complaints to abdominal pains are absent, a uterus almost always infantile. [bigmed.info]

• Oligomenorrhea

  neither estrogenic nor androgenic changes, such as endometrial hyperplasia, abnormal endometrial bleeding, oligomenorrhea, infertility, or virilization. [jpatholtm.org]

  Case Report A 32-year-old gravida 0 woman presented with hirsutism, oligomenorrhea, and morbid obesity with a body mass index of 37 kg/m2. Family history was negative for known genetic syndromes, including Von Hippel–Lindau and Lynch syndromes. [docksci.com]

  Only at one patient the signs indicating androgenic activity (a hirsutism and an oligomenorrhea) are noted. [bigmed.info]

  Fewer than 5% of the patients are younger than the age of normal puberty, and approximately three quarters of these children exhibit isosexual pseudoprecocity. 4 In adult patients, menstrual disturbances such as menometrorrhagia, oligomenorrhea, and amenorrhea [glowm.com]

  […] studies. [72] The well-differentiated tumors occur at an average age of 35 years and retiform tumors at an average age of 15 years. [44] Clinical features About one third of patients with Sertoli-Leydig cell tumor have androgenic manifestations including: oligomenorrhea [emedicine.medscape.com]

• Primary Amenorrhea

  amenorrhea. ( 4744425 ) 1973 31 Plasma steroids in two subjects with ovarian androgen-producing tumors arrhenoblastoma and gynandroblastoma. ( 4334770 ) Laatikainen T....Vihko R. 1972 32 Spontaneous rupture of gynandroblastoma during labor. [malacards.org]

  Also primary amenorrhea is observed. Mammary glands are usually developed poorly, the tendency to infantility of external genitals and a hypertrophy of a clitoris is noted. [bigmed.info]

The diagnosis and treatment for patients with gynandroblastoma is also discussed. [ncbi.nlm.nih.gov]

A histopathological examination showed gynandroblastoma composed of juvenile granulosa and Sertoli-Leydig cells, chirurgical treatment was completed by total hysterectomy with right adnexectomy, omentectomy with no proof of malignant cells. [ijrcog.org]

Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. [books.google.com]

The prognosis is favorable and similar to that of the individual tumor components, but clinical follow-up in the small number of cases has been limited. [ncbi.nlm.nih.gov]

The prognosis is favorable and similar to that of the individual tumor components, but clinical follow-up in the small number of cases has been limited. 1997International Society of Gynecological Pathologists [journals.lww.com]

Diagnosis - Gynandroblastoma * Colon & Rectal Cancer: Home Testing - Home Colorectal Cancer Tests - Home Fecal Occult Bleeding Tests Prognosis - Gynandroblastoma Not supplied. Treatment - Gynandroblastoma Not supplied. [checkorphan.org]

[…] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]

The neoplasm occurs mainly during the first 3 decades of life. [1] Etiology The etiology of JGCT is unknown. [emedicine.medscape.com]

Etiology There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder [atlasgeneticsoncology.org]

Because the etiology of a disease is not clear yet, there is no standard scheme of treatment. A number of gynecologists recommend to carry out hormonal treatment in the cyclic mode or treatment by gonadotrophins according to the standard scheme. [bigmed.info]

English : BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

FOLLOW UP RECOMMENDATIONS Physical exam every 3 months for the first 2 years after diagnosis, every 6 months until 5 years, and then annually thereafter If CA-125 elevated... 1 Beral V, Doll R, Hermon C, et al; and Collaborative Group on Epidemiological [5minuteconsult.com]

Cancer standardized incidence ratios were determined relative to the Surveillance, Epidemiology, and End Results (SEER) program (which does not capture all DICER1 -associated neoplasms). [ascopost.com]

Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors. [emedicine.medscape.com]

Prevention - Gynandroblastoma Not supplied. Diagnosis - Gynandroblastoma * Colon & Rectal Cancer: Home Testing - Home Colorectal Cancer Tests - Home Fecal Occult Bleeding Tests Prognosis - Gynandroblastoma Not supplied. [checkorphan.org]

[…] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention [decs.bvs.br]

Clinical prevention of tumors of ovaries is based hl. obr. on early detection and treatment of pretumor diseases. The large role in it is played by annual routine maintenances. [bigmed.info]