Presentation
All contained SLCT or Sertoli cell tumour components. aGCT and jGCT components were identified in seven and 10 cases, respectively, with one presenting both components. [ncbi.nlm.nih.gov]
Children with PPB may present with shortness of breath and pneumothorax due to cyst rupture. In cases of advanced disease, they may additionally present with weight loss and fever. PMID: 8636815, 25209242, 19556464. [dicer1syndrome.ca]
Entire Body System
- Infertility
We found that the increased level of serum testosterone in the patient was the reason for amenorrhea and infertility. The diagnosis and treatment for patients with gynandroblastoma is also discussed. [ncbi.nlm.nih.gov]
October 01, 2010 [Phenomenological study of infertile women with obesity]. October 01, 2010 [Lactic acid and lactoserum in vulvovaginal infections]. October 01, 2010 [Birth defects associated with increased nuchal translucency]. [medscape.com]
Clinical and molecular genetics of growth and development Clinical and molecular mechanism of mole infertility [researchmap.jp]
[…] literature review. ( 23552209 ) 2013 9 The C134W (402 C>G) FOXL2 mutation is absent in ovarian gynandroblastoma: insights into the genesis of an unusual tumour. ( 22296244 ) Oparka R....Herrington C.S. 2012 10 Gynandroblastoma with the symptoms of infertility [malacards.org]
- Weakness
They continually emit weak electric discharges, which they use in object location and communication. A most popular species of research interest is the electric eel, ELECTROPHORUS electricus. [healthdictionary.info]
diffuse + weak, diffuse strong, diffuse – Complete Mole – strong, diffuse weak, focal weak, focal strong, diffuse – Choriocarcinoma – strong, diffuse weak, focal weak, focal strong, diffuse – Placental Site Tumor strong, focal strong, diffuse strong [diagomics.com]
A recent study found 20 of 78 adenocarcinomas from various sites to be positive for α inhibin. 61 However, in these cases positive staining is generally weak, contrasting with the usual strong positivity in ovarian sex cord stromal tumours (fig 4). [jcp.bmj.com]
Inhibin expression may be present but is usually weak. Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors. [emedicine.medscape.com]
- Fishing
Gymnotids An order of neotropical electric fish found chiefly in the waters of South America. They continually emit weak electric discharges, which they use in object location and communication. [healthdictionary.info]
In a study, FISH using DNA-specific probes for chromosome 12, 17, 22 and X on granulosa cell tumours revealed monosomy 22 in 6/20; trisomy 12 in 5/20; monosomy X in 2/20 and monosomy 17 in 1/20. [atlasgeneticsoncology.org]
- Surgical Procedure
PREVIOUS AND NEXT TERMS -------------------------------------- Gynecologic Surgical Procedures Surgery performed on the female genitalia. Gynecologic Surgical Procedure Surgery performed on the female genitalia. [healthdictionary.info]
- Inflammation
One of the four signs of inflammation (t., calor, dolor, rubor) enunciated by Celsus. [medicine.academic.ru]
Sclerous changes in tissue of an ovary as result hron. it is difficult to distinguish inflammations from the sclerosis (see) which is a consequence of atrophic process. [bigmed.info]
Gastrointestinal
- Acute Abdomen
The differential diagnosis of torsion of a leg of a cyst with other morbid conditions and diseases causing a symptom complex of an acute abdomen (see. Acute abdomen, table). [bigmed.info]
Skin
- Hirsutism
A 66-year-old woman without metrorrhagia or hirsutism presented with abdominal pain and slightly elevated serum estradiol levels. [ncbi.nlm.nih.gov]
Case Report A 32-year-old gravida 0 woman presented with hirsutism, oligomenorrhea, and morbid obesity with a body mass index of 37 kg/m2. Family history was negative for known genetic syndromes, including Von Hippel–Lindau and Lynch syndromes. [docksci.com]
SLCT frequently presents with signs of virilisation (hirsutism, voice changes), along with typical features of an ovarian neoplasm, including abdominal distension and pain. PMID: 21205968, 21501861, 25844550, 27858560. [dicer1syndrome.ca]
It typically secretes androgens, and as a result women with this tumour often present with new onset of hirsutism or virilisation. Leydig cell tumour. [dictionnaire.sensagent.leparisien.fr]
At most of patients the hirsutism of various degree is observed (see the Hirsutism). Complaints to abdominal pains are absent, a uterus almost always infantile. [bigmed.info]
- Acne Vulgaris
Overview A type of ovarian tumor that causes feminizing and masculinizing effects of estrogen and androge Symptoms - Gynandroblastoma * Abnormal menstrual bleeding * Hirsuitism * Poor libido * Masculine voice * Acne vulgaris * Beard-like facial hair * [checkorphan.org]
Psychiatrical
- Suggestibility
Computed tomography scan showed a left adnexal mixed density pelvic mass suggesting malignant ovarian tumour. [ncbi.nlm.nih.gov]
CONCLUSIONS: This suggests that, despite their similar morphological appearances, the GCT-like component of gynandroblastoma has a different molecular basis from conventional adult-type GCT. [research.ed.ac.uk]
Conclusions: This suggests that, despite their similar morphological appearances, the GCT- like component of gynandroblastoma has a different molecular basis from conventional adult- type GCT. [discovery.dundee.ac.uk]
Urogenital
- Amenorrhea
A left ovarian gynandroblastoma in a 24-year-old woman was clinically manifest by prolonged (7 years) amenorrheas interrupted by metrorrhagies, with moderate hypertrichosis is presented. [ncbi.nlm.nih.gov]
23552209 ) 2013 9 The C134W (402 C>G) FOXL2 mutation is absent in ovarian gynandroblastoma: insights into the genesis of an unusual tumour. ( 22296244 ) Oparka R....Herrington C.S. 2012 10 Gynandroblastoma with the symptoms of infertility and secondary amenorrhea [malacards.org]
Treatment
The present findings can help clinicians make an accurate preoperative imaging diagnosis of gynandroblastoma with a juvenile granulosa cell component and plan an adequate treatment strategy for this rare, potentially malignant neoplasm. [ijrcog.org]
There are two main types of clinical studies: Clinical trials determine if a new test or treatment for a disease is effective and safe by comparing groups receiving different tests/treatments. [rarediseases.info.nih.gov]
Because of the importance of multimodality treatment, the site-specific chapters are co-authored by a surgical oncologist, a medical oncologist, a radiation oncologist, and a pathologist. [books.google.com]
Prognosis
The prognosis is favorable and similar to that of the individual tumor components, but clinical follow-up in the small number of cases has been limited. [ncbi.nlm.nih.gov]
Diagnosis - Gynandroblastoma * Colon & Rectal Cancer: Home Testing - Home Colorectal Cancer Tests - Home Fecal Occult Bleeding Tests Prognosis - Gynandroblastoma Not supplied. Treatment - Gynandroblastoma Not supplied. [checkorphan.org]
The prognosis is favorable and similar to that of the individual tumor components, but clinical follow-up in the small number of cases has been limited. ©1997International Society of Gynecological Pathologists [journals.lww.com]
Hinney Medicine Der Gynäkologe 2005 The majority of hormone producing ovarian tumors (90%) belongs to the group of sex cord-stromal tumors, many of these tumors are benign or have a low malignant potential and a good prognosis (thekoma, fibroma, gynandroblastoma [semanticscholar.org]
Etiology
[…] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]
The neoplasm occurs mainly during the first 3 decades of life. [1] Etiology The etiology of JGCT is unknown. [emedicine.medscape.com]
Etiology There appear to be several established clinical syndromes associated with several subtypes of sex cord-stromal tumours. 30% of patients with sex cord tumours with annular tubules have Peutz-Jeghers syndrome (PJS), an autosomal dominant disorder [atlasgeneticsoncology.org]
Because the etiology of a disease is not clear yet, there is no standard scheme of treatment. A number of gynecologists recommend to carry out hormonal treatment in the cyclic mode or treatment by gonadotrophins according to the standard scheme. [bigmed.info]
Epidemiology
English : BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]
FOLLOW UP RECOMMENDATIONS Physical exam every 3 months for the first 2 years after diagnosis, every 6 months until 5 years, and then annually thereafter If CA-125 elevated... 1 Beral V, Doll R, Hermon C, et al; and Collaborative Group on Epidemiological [5minuteconsult.com]
Cancer standardized incidence ratios were determined relative to the Surveillance, Epidemiology, and End Results (SEER) program (which does not capture all DICER1 -associated neoplasms). [ascopost.com]
Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors. [emedicine.medscape.com]
Epidemiology Sex cord-stromal ovarian neoplasms are rare, and the incidence is estimated around 0.2 per 100,000 women [ 1 ]. [radiologykey.com]
Prevention
Prevention - Gynandroblastoma Not supplied. Diagnosis - Gynandroblastoma * Colon & Rectal Cancer: Home Testing - Home Colorectal Cancer Tests - Home Fecal Occult Bleeding Tests Prognosis - Gynandroblastoma Not supplied. [checkorphan.org]
[…] diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology GE genetics HI history IM immunology ME metabolism MI microbiology MO mortality NU nursing PS parasitology PA pathology PP physiopathology PC prevention [decs.bvs.br]
Participating in research helps researchers ultimately uncover better ways to treat, prevent, diagnose, and understand human diseases. What Are Clinical Studies? Clinical studies are medical research involving people as participants. [rarediseases.info.nih.gov]
Clinical prevention of tumors of ovaries is based hl. obr. on early detection and treatment of pretumor diseases. The large role in it is played by annual routine maintenances. [bigmed.info]