Presentation
Individuals with habitual abortion presented with an abnormal expression of IL-1beta and IL-6 mRNA in endometrium, during the mid-secretory phase. [ncbi.nlm.nih.gov]
If you are looking for ASRM Scientific Congress Presenter Guidelines, please go to the Congress Website Presenter Resources [asrm.org]
Occasionally, the woman may present with severe shock. [clinicalgate.com]
Entire Body System
- Infertility
The study supports the hypothesis that infertility, recurrent miscarriage and pre-eclampsia share elements of the same aetiological factors. [ncbi.nlm.nih.gov]
N97.0 Female infertility associated with anovulation N97.1 Female infertility of tubal origin N97.2 Female infertility of uterine origin N97.8 Female infertility of other origin N97.9 Female infertility, unspecified N98 Complications associated with [icd10data.com]
- Pathologist
The pathologist then accurately dated the biopsy samples using LH assays to pinpoint the time of ovulation. LPD was believed to be the cause in 17% of these recurrent miscarriages. [emedicine.medscape.com]
Professor Sokrat Meksi, with 35 years experience as a forensic pathologist, suggested that domestic violence had increased since the end of the communist period. [refworld.org]
Gastrointestinal
- Diarrhea
A “new episode of diarrhea” was defined as the occurrence of diarrhea separated from a previous diarrhea episode by ⩾1 week. [academic.oup.com]
diarrhea: HR, 0.64 [95% CI, 0.41–1.00]; P = .051). [pediatrics.aappublications.org]
Astrovirus infections are marked by symptoms such as diarrhea, vomiting, abdominal cramping, headache, fever, and mild dehydration. [contagionlive.com]
Polyhydramnios 109 Lower Limb Cramping Pain During Pregnancy 115 Lower Limb Varicose Veins During Pregnancy 117 Pruritic Urticarial Papules Plaques of Pregnancy 121 Colds Plus During Pregnancy 125 Cough During Pregnancy 129 Hoarseness During Pregnancy 137 Diarrhea [books.google.de]
In addition, a highly divergent member of this family, astrovirus MLB1, was recently identified in patients with diarrhea (5, 6). [jvi.asm.org]
- Blood in Stool
Fecal occult blood test, which checks your stool for blood that’s not visible to the naked eye Endoscopy Biopsy, when a doctor takes a small piece of tissue from your stomach to look for signs of cancer. Your doctor may do this during an endoscopy. [webmd.com]
Workup
The authors also conclude, "that hysteroscopy should be a part of the diagnostic workup of infertile women complaining of unexplained recurrent miscarriage." [en.wikipedia.org]
It is of utmost importance that the laboratory has its interest invested in infertility workups. [fertilitysolution.com]
Most patients with a history of recurrent miscarriage do not benefit from an extensive infection workup. For related information, see the following Medscape Reference articles. [emedicine.medscape.com]
Treatment
Antibiotic treatment seems to be associated with an improved reproductive outcome. [ncbi.nlm.nih.gov]
Like treatment timing and duration, there was great heterogeneity in the mode of treatment administration. The majority of trials administered intervention intravenously, although some also administered treatment intramuscularly and subcutaneously. [doi.org]
One study found that in many women with chronic endometritis, "fertility was restored after appropriate antibiotic treatment."There are currently no treatments for women with unexplained recurrent pregnancy loss. [en.wikipedia.org]
Prognosis
Management – Unexplained RM Good prognosis for future pregnancy outcome 75% chance of a eventual live birth in subsequent pregnancy However, prognosis worsens with: Increasing maternal age Number of previous miscarriages Maternal age and number [slideshare.net]
In all patients, genetic variants associated with low plasma mannose binding lectin or thrombophilia affect the prognosis negatively. [forskning.ku.dk]
What is the prognosis for H. pylori infections? What if it is not treated? Many infections are mild and produce few, if any, symptoms. The prognosis of these infections is excellent. [medicinenet.com]
* Disease is ‘‘any deviation from or interruption of the normal structure or function of any part, organ, or system of the body as manifested by characteristic symptoms and signs; the etiology, pathology, and prognosis may be known or unknown.’’ [web.archive.org]
Prognosis The prognosis is usually excellent, even in patients with complications, such as gastric MALToma. However, the prognosis becomes poor for patients who develop squamous cell esophageal cancer or gastric carcinoma. [emedicine.medscape.com]
Etiology
If patients are evaluated with an etiology in mind, a comprehensive study and management can be planned that will save time and expense. [ncbi.nlm.nih.gov]
Astroviruses were second only to rotaviruses as etiologic agents of nosocomial diarrhea, accounting for ∼12% of cases and nearly half as many cases as rotavirus. [academic.oup.com]
Epidemiology
Epidemiological, immunogenetic and immunological studies support the hypothesis that aberrant maternal H-Y immune responses have a pathogenic role in SRM. [ncbi.nlm.nih.gov]
Werler, Induced Abortions and the Risk of Preeclampsia Among Nulliparous Women, American Journal of Epidemiology, 182, 8, (663), (2015). [doi.org]
Regarding epidemiology it should be noted that the incidence of clinical abortion in the general population is 12-15%. [creafampuebla.com]
What This Study Adds: We present the most comprehensive description of astrovirus epidemiology in young children to date. [pediatrics.aappublications.org]
Epidemiology varies depending on the age of the mother. A mother under age 30, has only 25% chances to have another abortion. On the other hand, being older than 40 increases the rate up to 50-60%. [invitra.com]
Pathophysiology
H. (2011) Obstetric antiphospholipid syndrome: an update on pathophysiology and management. Semin Reprod Med, 29, 522–539. doi: 10.1055/s-0031-1293206. Schist, D. J., & Hill, J. A. (2002) Recurrent Pregnancy Loss. [zmj.zsmu.edu.ua]
If the vascular hypothesis for the pathophysiology of miscarriage is accepted ( Hustin and Jauniaux 1997 ), bed rest may improve pressure variation and flow changes, and therefore improve the outcome. [clinicalgate.com]
Implications for research Effective treatment of an alleged alloimmune cause of recurrent miscarriage awaits more complete knowledge of the underlying pathophysiology. [doi.org]
Pathophysiology The most common route of H pylori infection is either oral-to-oral (stomach contents are transmitted from mouth to mouth) or fecal-to-oral (from stool to mouth) contact. [2] Parents and siblings seem to play a primary role in transmission [emedicine.medscape.com]
01) A randomized study of thromboprophylaxis in women with unexplained consecutive recurrent abortions. (2006-02) Anticoagulants for the treatment of recurrent pregnancy loss in women without antiphospholipid syndrome. (2005-01) Recurrent abortion: pathophysiology [2womenshealth.com]
Prevention
How else can a woman try to prevent recurrent pregnancy loss? Q. What is a miscarriage? A. A miscarriage is a pregnancy loss before five months gestation. Back to Top Q. How common is miscarriage? A. [web.archive.org]
With this information about the likely cause of repeat miscarriage, researchers hope to develop new preventative treatments for pregnancy loss. [medicaldaily.com]
Abstract In order to investigate the possible role of suppressor cells in paternal leukocyte immunization to prevent recurrent miscarriages, peripheral blood lymphocytes from habitually aborting women before and after immunization were assessed. [ncbi.nlm.nih.gov]
& control, therapy) Abortion, Spontaneous (classification, diagnosis, pathology, prevention & control, therapy) Adult Chromosome Aberrations Female Luteinizing Hormone (metabolism) Pregnancy Complications, Infectious (immunology, prevention & control [medvik.cz]
However, there is currently no drug that has evidence of preventing recurrent pregnancy loss by boosting maternal immune tolerance; aspirin has no effect in this case. [diki.pl]