infection Auten et al. [ 11 ] 74 M Spine, epidural Dental None Tissue Laminectomy Negative TMP/SMX 8 and tobramycin 7 weeks Cure Pravda and Habermann [ 12 ] 78 F Knee Yes Dental None Synovial fluid Arthrotomy Negative Ampicillin and amoxicillin 12 weeks [ncbi.nlm.nih.gov]

Studies into the nature of this biofilm structure and proteins will help develop strategies to fight chronic infections. [emedicine.medscape.com]

Exacerbations of chronic bronchitis (treat if there is increased sputum production, purulent sputum or dyspnoea): treat for five days (longer in severely ill patients) with amoxicillin, tetracycline or clarithromycin; some H. influenzae strains are tetracycline-resistant [patient.info]

Case report A 41 year old woman presented to her GP with a 10 day history of pyrexia, cough with purulent sputum, and general malaise. [thorax.bmj.com]

Symptoms of acute bronchitis include increased shortness of breath, cough, and production of purulent sputum; in more severe cases, fever and an increased white blood cell count may also be present. [ncbi.nlm.nih.gov]

METHODS: A 22-day old baby presented with excessive crying, refusal of feed, progressive abdominal distension, fever and vomiting. Besides clinical assessment, body fluids were cultured. [ncbi.nlm.nih.gov]

H. ducreyi causes a venereal disease in humans known as chancroid, or soft chancre. [britannica.com]

Chancres due to H ducreyi are tender, somewhat irregular, and slightly indurated; they may be confused with primary syphilitic chancres, traumatic lesions of the penis (especially with bacterial superinfection), fixed drug eruptions, or ulcerated herpetic [ncbi.nlm.nih.gov]

[…] chronic bronchitis, sinusitis, conjunctivitis, and otitis media, and occur frequently in lower respiratory tract of patients with cystic fibrosis during acute exacerbations. (2) H. ducreyi appears to be the causative agent of the venereal disease soft chancre [catalog.hardydiagnostics.com]

Presentations include meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis and vesicular eruption. Investigations[5] Gram stain: small, Gram-negative, pleomorphic coccobacilli with polymorphonuclear cells. [patient.info]

Chancres due to H ducreyi are tender, somewhat irregular, and slightly indurated; they may be confused with primary syphilitic chancres, traumatic lesions of the penis (especially with bacterial superinfection), fixed drug eruptions, or ulcerated herpetic [ncbi.nlm.nih.gov]

HIV infection), alcoholism, pregnancy, and malignancy Neonatal infections: May have nonspecific manifestations; may include signs/symptoms of bacteremia, sepsis, meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis, and vesicular eruption [emedicine.medscape.com]

Subsequently, the patient develops petechiae, purpura, shock and may face death. The pathogenesis of this infection is poorly understood. The growth conditions for this organism are the same as those for H. influenzae. [microbiologybook.org]

Lesions that resemble a syphilitic chancre result from sexual contact with an infected individual; they are usually found on the genitals. [ncbi.nlm.nih.gov]

Diagnosis Haemophilus influenzae meningitis cannot be distinguished on the basis of clinical presentation, physical examination, or cerebrospinal fluid abnormalities from meningitis due to other common bacterial pathogens. [ncbi.nlm.nih.gov]

Pneumonia may result, with patchy or segmental pulmonary infiltrates detectable by radiography. Gram stain of sputum reveals a profusion of Gram-negative coccobacilli ( Fig. 30-3 ), but no other pathogenic bacteria. [ncbi.nlm.nih.gov]

H. parainfluenzae (most common) H. parahaemolyticus Taxonomy changes: reclassification from Haemophilus spp.[21] H. aphrophilus is now Aggregatibacter aphrophilus (see module) H. paraphrophilus is now Aggregatibacter paraphrophilus (see module) H. segnis [hopkinsguides.com]

Aggregatibacter aphrophilus comb. nov., and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates. Int J Syst Evol Microbiol 56 : 2135 – 2146. 4. [asmscience.org]