METHODS: A 22-day old baby presented with excessive crying, refusal of feed, progressive abdominal distension, fever and vomiting. Besides clinical assessment, body fluids were cultured. [ncbi.nlm.nih.gov]

Hib, for example may present as epiglottitis (severe swelling in the throat) or pneumonia. [immune.org.nz]

• Chronic Infection

  infection Auten et al. [ 11 ] 74 M Spine, epidural Dental None Tissue Laminectomy Negative TMP/SMX 8 and tobramycin 7 weeks Cure Pravda and Habermann [ 12 ] 78 F Knee Yes Dental None Synovial fluid Arthrotomy Negative Ampicillin and amoxicillin 12 weeks [ncbi.nlm.nih.gov]

  Studies into the nature of this biofilm structure and proteins will help develop strategies to fight chronic infections. [emedicine.medscape.com]

• Purulent Sputum

  Exacerbations of chronic bronchitis (treat if there is increased sputum production, purulent sputum or dyspnoea): treat for five days (longer in severely ill patients) with amoxicillin, tetracycline or clarithromycin; some H. influenzae strains are tetracycline-resistant [patient.info]

  Case report A 41 year old woman presented to her GP with a 10 day history of pyrexia, cough with purulent sputum, and general malaise. [thorax.bmj.com]

  Symptoms of acute bronchitis include increased shortness of breath, cough, and production of purulent sputum; in more severe cases, fever and an increased white blood cell count may also be present. [ncbi.nlm.nih.gov]

• Abdominal Distension

  METHODS: A 22-day old baby presented with excessive crying, refusal of feed, progressive abdominal distension, fever and vomiting. Besides clinical assessment, body fluids were cultured. [ncbi.nlm.nih.gov]

• Chancre

  H. ducreyi causes a venereal disease in humans known as chancroid, or soft chancre. [britannica.com]

  Chancres due to H ducreyi are tender, somewhat irregular, and slightly indurated; they may be confused with primary syphilitic chancres, traumatic lesions of the penis (especially with bacterial superinfection), fixed drug eruptions, or ulcerated herpetic [ncbi.nlm.nih.gov]

  […] chronic bronchitis, sinusitis, conjunctivitis, and otitis media, and occur frequently in lower respiratory tract of patients with cystic fibrosis during acute exacerbations. (2) H. ducreyi appears to be the causative agent of the venereal disease soft chancre [catalog.hardydiagnostics.com]

• Eruptions

  Presentations include meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis and vesicular eruption. Investigations[5] Gram stain: small, Gram-negative, pleomorphic coccobacilli with polymorphonuclear cells. [patient.info]

  Chancres due to H ducreyi are tender, somewhat irregular, and slightly indurated; they may be confused with primary syphilitic chancres, traumatic lesions of the penis (especially with bacterial superinfection), fixed drug eruptions, or ulcerated herpetic [ncbi.nlm.nih.gov]

  HIV infection), alcoholism, pregnancy, and malignancy Neonatal infections: May have nonspecific manifestations; may include signs/symptoms of bacteremia, sepsis, meningitis, pneumonia, respiratory distress, scalp abscess, conjunctivitis, and vesicular eruption [emedicine.medscape.com]

• Purpura

  Subsequently, the patient develops petechiae, purpura, shock and may face death. The pathogenesis of this infection is poorly understood. The growth conditions for this organism are the same as those for H. influenzae. [microbiologybook.org]

• Syphilitic Chancre

  Lesions that resemble a syphilitic chancre result from sexual contact with an infected individual; they are usually found on the genitals. [ncbi.nlm.nih.gov]

All strains of H. influenzae genogroup b were isolated during routine urine culture workups at the VA Puget Sound Health Care System Clinical Microbiology Laboratory or the Houston VA Medical Center. [jcm.asm.org]

[…] presence of cellulitis Joint, lung, and sinus aspiration Transtracheal aspiration Tympanocentesis Pericardiocentesis Laparoscopy and tubal cultures in women: For suspected NTHi Culdocentesis and peritoneal fluid cultures in women: For suspected NTHi See Workup [emedicine.medscape.com]

• Cerebrospinal Fluid Abnormality

  Diagnosis Haemophilus influenzae meningitis cannot be distinguished on the basis of clinical presentation, physical examination, or cerebrospinal fluid abnormalities from meningitis due to other common bacterial pathogens. [ncbi.nlm.nih.gov]

• Pulmonary Infiltrate

  Pneumonia may result, with patchy or segmental pulmonary infiltrates detectable by radiography. Gram stain of sputum reveals a profusion of Gram-negative coccobacilli ( Fig. 30-3 ), but no other pathogenic bacteria. [ncbi.nlm.nih.gov]

• Aggregatibacter Aphrophilus

  H. parainfluenzae (most common) H. parahaemolyticus Taxonomy changes: reclassification from Haemophilus spp.[21] H. aphrophilus is now Aggregatibacter aphrophilus (see module) H. paraphrophilus is now Aggregatibacter paraphrophilus (see module) H. segnis [hopkinsguides.com]

  Aggregatibacter aphrophilus comb. nov., and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates. Int J Syst Evol Microbiol 56 : 2135 – 2146. 4. [asmscience.org]

Back in the Netherlands, a painful ulcer developed at the same body location, and despite treatment with flucloxacillin, his complaints worsened. [ncbi.nlm.nih.gov]

Some people with certain medical conditions have an increased risk of infection, for example, those without a functioning spleen, and those who are immune compromised from a disease or treatment of a disease. [immune.org.nz]

There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances. [healthychildren.org]

Treatment and prognosis Mortality rates in patients with H. influenzae pneumonia have been reported as ranging around 10-42% Promoted articles (advertising) [radiopaedia.org]

Prognosis The sequelae following Hib meningitis may include deafness, convulsions and intellectual impairment. [patient.info]

The prognosis of uncomplicated Hib pneumonia and nonencapsulated H influenzae infections is usually good. [emedicine.medscape.com]

An acute infectious disease, clinically manifested by hoarseness and stenosis of the respiratory tract (up to asphyxiation), is epiglottitis, the etiological factor of which in most cases is Haemophilus influenzae, type B. [mlst.net]

The Pneumonia Etiology Research for Child Health Project: a 21st century childhood pneumonia etiology study. Clin Infect Dis 2012;54 Suppl 2:S93–101. . PMID:22403238 110. Claesson BA, Lagergård T, Trollfors B. [pneumonia.biomedcentral.com]

The oral cavity is usually a likely source of the etiologic agents in infections caused by these organisms. Such infections include endocarditis, brain abscesses, jaw infections and infections following human bites or finger sucking. [catalog.hardydiagnostics.com]

Vishniakova LA, Putov NV (1990) The etiology of acute pneumonia. Ter Arkh 62: 15-18. Sinopalnikov A, Romanov AG (2006) An infectious exacerbation of chronic obstructive pulmonary disease. Pulmonology 1. [omicsonline.org]

Key words: Haemophilus influenzae - storage - culture media Haemophilus influenzae is an etiological agent of a wide variety of infectious diseases in human beings, from non-complicated ones such as conjunctivitis and otitis media, to invasive, potentially [scielo.br]

Epidemiology of Haemophilus influenzae type b infections. Pediatrics. 1990 ; 85 : 631 – 5. PubMed Peltola H. [wwwnc.cdc.gov]

An important epidemiologic aspect of Hib disease is the risk that it poses to contacts of the affected person. [emedicine.medscape.com]

An epidemiologic study with special reference to day-care centers. JAMA 1984; 252(18):2581-2584. Shapiro ED, Ward JI. The epidemiology and prevention of disease caused by Haemophilus influenzae type b. Epidemiol Rev 1991; 13:113-142.Tsang R. [ecdc.europa.eu]

We therefore studied the effect of the nasopharyngeal microbiome on viral load and mucosal cytokine responses, two important factors influencing the pathophysiology of RSV disease. [ncbi.nlm.nih.gov]

[…] settings where the test may be helpful Assessing a patient's immunological (IgG) response to Haemophilus influenzae type B (HIB) vaccine Assessing immunity against HIB Aiding in the evaluation of immunodeficiency Clinical Information Discusses physiology, pathophysiology [mayomedicallaboratories.com]

Pathophysiology The nomenclature (Haemophilus is Greek for "blood loving") acknowledges the fact that H influenzae requires 2 erythrocyte factors for growth: X (hemin) and V (nicotinamide-adenine-dinucleotide). [emedicine.medscape.com]

Risk in Hawaii Prevention There is a vaccine that can prevent Haemophilus influenzae type b (Hib) disease. This vaccine does not prevent disease caused by other types of H. influenzae. [health.hawaii.gov]

How can Hib disease be prevented? The best way to prevent Hib disease is to ensure all children are vaccinated according to the National Immunisation Program Schedule (see below). [healthywa.wa.gov.au]

Prevention: Immunization of all infants prevents H. influenzae type b infection. Respiratory and hand hygiene prevent transmission. Recent Washington trends: 4 to 13 cases (due to all serotypes) are reported annually. [doh.wa.gov]

CONCLUSION: There is the need to provide serological and molecular facilities for typing Nigerian Haemophilus infulenzae strain(s) to enhance the development of appropriate vaccine that will be most suitable for prevention of infection due to this organism [ncbi.nlm.nih.gov]

There is a vaccine to prevent Hib disease. All children younger than 5 years of age should be vaccinated with the Hib vaccine. Centers for Disease Control and Prevention Epiglottitis (Mayo Foundation for Medical Education and Research) [medlineplus.gov]