Presentation
Presents important “take home concepts within each chapter to help you recall clinical pearls. Includes the most need-to-know basic science, focusing on providing clear implications for patient care. [books.google.de]
The case involves a 37-year-old man with underlying illnesses, who has presented with fever, productive cough, runny nose and shortness of breath since August 2. [info.gov.hk]
Two cases presented with bacteraemia, and one case presented with meningitis. [hps.scot.nhs.uk]
This diagnosis should still be considered when a person presents with fever and signs of upper respiratory obstruction resembling croup. [www2.health.vic.gov.au]
Hib, for example may present as epiglottitis (severe swelling in the throat) or pneumonia. [immune.org.nz]
Entire Body System
- Sepsis
Massive lobular pneumonia and sepsis due to nontypable H. influenzae was found, in spite of H. influenzae type b vaccine being available. [dovepress.com]
Key words Haemophilus influenzae Chorioamnionitis Amniotic infection Sepsis in pregnancy This is a preview of subscription content, log in to check access. [link.springer.com]
Bacteremia can lead to any of the above illnesses or to sepsis, a dangerous whole-body response to infection. Sepsis can damage many organs or even cause death if not treated right away. Despite its name, Hib doesn't cause influenza (the flu). [kidshealth.org]
A cluster of early neonatal sepsis and pneumonia caused by nontypeable Haemophilus influenzae. Pediatr Infect Dis J 23, 1061 –1062. [jmm.microbiologyresearch.org]
Neonatal and maternal sepsis. Neonatal sepsis caused by nontypeable H. influenzae is being recognized with increasing frequency. [infectiousdiseaseadvisor.com]
- Splenectomy
Before and after splenectomy Hib is an uncommon cause of post-splenectomy sepsis in adults and children. Children older than 2 years who have received all scheduled doses of Hib vaccine do not require a booster dose after splenectomy. [www2.health.vic.gov.au]
However, the frequency of Hib infections is increased in patients with asplenia, splenectomy, sickle cell disease, malignancies and congenital or acquired immunodeficiencies. [patient.info]
Some experts suggest administering a dose prior to elective splenectomy regardless of prior vaccination history ( Source : American Academy of Pediatrics. Haemophilus influenzaeinfections. In: Pickering L, Baker C, Kimberlin D, Long S, eds. [hopkinsguides.com]
The frequency of Hib infections in patients with asplenia, splenectomy, sickle cell disease, malignancies, and congenital or acquired immunodeficiencies is higher than in individuals without these conditions. [emedicine.medscape.com]
Neurologic
- Encephalopathy
Only 8 (7.3%), including 5 born prematurely, had comorbidities: congenital diaphragmatic hernia (n = 2), severe hypoxic-ischemic encephalopathy (n = 2), autosomal polycystic kidney disease (n = 1), congenital heart disease (n = 1), hypothyroidism (n = [cid.oxfordjournals.org]
Workup
[…] presence of cellulitis Joint, lung, and sinus aspiration Transtracheal aspiration Tympanocentesis Pericardiocentesis Laparoscopy and tubal cultures in women: For suspected NTHi Culdocentesis and peritoneal fluid cultures in women: For suspected NTHi See Workup [emedicine.medscape.com]
Treatment
Antibiotics and supportive care These are the mainstays of treatment. [emedicine.medscape.com]
Some of these opinions may contain information about treatment or uses of drug products that have not been approved by the U.S. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. [webmd.com]
Blood tests What is the treatment for H. influenzae infections? Treatment for H. influenzae greatly depends on which area of the body is infected. [stanfordchildrens.org]
Uses extensive color-coded algorithms to facilitate quick diagnosis, management, and treatment decisions. Organizes material to parallel your clinical decision making process. [books.google.de]
Prognosis
Treatment and prognosis Mortality rates in patients with H. influenzae pneumonia have been reported as ranging around 10-42% Promoted articles (advertising) [radiopaedia.org]
Outlook / Prognosis What can I expect if my child has a Haemophilus influenzae disease? The outlook (prognosis) for H. influenzae infections depends on the type and severity of your child’s condition. [my.clevelandclinic.org]
Prognosis The sequelae following Hib meningitis may include deafness, convulsions and intellectual impairment. [patient.info]
Moreover, there seemed to be a better prognosis than that previously described for C. jejuni-related Guillain–Barré syndrome patients (Rees et al., 1995a; Visser et al., 1995; Jacobs et al., 1996). [academic.oup.com]
The prognosis of uncomplicated Hib pneumonia and nonencapsulated H influenzae infections is usually good. [emedicine.medscape.com]
Etiology
S. pneumoniae and H. influenzae are the most frequent pathogens responsible for respiratory tract infections etiology. [ibn.idsi.md]
A consistent chapter format enables you to rapidly and effortlessly locate the most current protocols on manifestations, etiologies, triggers, approaches to treatment, complications, and preventative strategies. [books.google.de]
The gold standard for an etiologic diagnosis, culture of middle ear fluid, requires tympanocentesis, which is an invasive procedure and is thus not routinely performed. [jcm.asm.org]
Etiologic Agent H. influenzae is a pleomorphic gram-negative coccobacillus. H. influenzae may be either encapsulated (typeable) or unencapsulated (nontypeable). [cdc.gov]
Vishniakova LA, Putov NV (1990) The etiology of acute pneumonia. Ter Arkh 62: 15-18. Sinopalnikov A, Romanov AG (2006) An infectious exacerbation of chronic obstructive pulmonary disease. Pulmonology 1. [omicsonline.org]
Epidemiology
Please refer any child care exposures as soon as possible to Epidemiology & Assessment at 714-834-8180 for follow-up. [cms.ocgov.com]
Date: 1998 University: Göteborgs universitet/University of Gothenburg Institution: Department of Otolaryngology Avdelningen för öron-, näs- och halssjukdomar Date of Defence: 1998-04-17 Publication type: Doctoral thesis Keywords: Haemophilus influenzae epidemiology [gupea.ub.gu.se]
Additionally, these studies demonstrated similar epidemiologic distributions as historically documented with Hib, with 22 of 23 reported Hia cases occurring in patients less than 5 years old. [journals.lww.com]
An epidemiologic study with special reference to day-care centers. JAMA 1984; 252(18):2581-2584. Shapiro ED, Ward JI. The epidemiology and prevention of disease caused by Haemophilus influenzae type b. Epidemiol Rev 1991; 13:113-142.Tsang R. [ecdc.europa.eu]
INTRODUCTION The epidemiology and clinical manifestations of Haemophilus influenzae infections have undergone dramatic changes in the last 2 decades. [jcm.asm.org]
Pathophysiology
The similarities between Guillain–Barré syndrome subsequent to H. influenzae and C. jejuni infections may reflect the same pathophysiology. [academic.oup.com]
Pathophysiology The nomenclature ( Haemophilus is Greek for "blood loving") acknowledges the fact that H influenzae requires 2 erythrocyte factors for growth: X (hemin) and V (nicotinamide-adenine-dinucleotide). [emedicine.medscape.com]
We filtered for pathogenic and likely pathogenic variation with no conflicting evidence and criteria provided by at least one submitter and checked our alignment for known variations that could potentially relate to Y. pestis and H. influenzae pathophysiology [genomebiology.biomedcentral.com]
Prevention
Corticosteroids may help prevent brain damage. Epiglottitis must also be treated as soon as possible. People may need help breathing. [merckmanuals.com]
[…] by Hib vaccine very rare in children and infants life-threatening infection of the area of the throat that covers and protects the windpipe Meningitis prevented by Hib vaccine very rare in children and infants infection of the membranes that surround [childrenshospital.org]
How can haemophilus influenzae be prevented? The Hib vaccine can prevent most serious cases of H flu disease. Those in close contact with people with serious H flu disease should receive preventive antibiotics. [drgreene.com]