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Haemophilus Influenzae Pneumonia

Pneumonia Hemophilus Influenza


Presentation

  • Its clinical presentation has been described as being similar to that seen in non-immunosuppressed hosts but clearly different to that of opportunistic pneumonias. An atypical presentation has rarely been seen.[ncbi.nlm.nih.gov]
  • She was commenced on immunoglobulin replacement following treatment of sepsis and remains well 18 months after the initial presentation.[ncbi.nlm.nih.gov]
  • A 2-year-old boy with symptoms of a minor upper respiratory tract infection developed Haemophilus influenzae pneumonia that presented as hypoxaemia under anaesthesia for minor emergency surgery.[ncbi.nlm.nih.gov]
  • We report 2 deaths in children presenting with fulminant pneumonia, complicated by sepsis and adult respiratory distress syndrome despite vigorous antibiotic therapy and full resuscitative measures.[ncbi.nlm.nih.gov]
  • Lobar consolidation was the most common radiological pattern, being present in 10 of the 15 cases. Type b was the commonest serotype isolated, but three cases were due to non-typable (non-capsulate) strains.[ncbi.nlm.nih.gov]
Cough
  • The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia.[ncbi.nlm.nih.gov]
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
  • In our study, cases basically involved a typical form of presentation, with cough, purulent expectoration, and dyspnea.[academic.oup.com]
Dyspnea
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • In our study, cases basically involved a typical form of presentation, with cough, purulent expectoration, and dyspnea.[academic.oup.com]
  • Infection of lung by Haemophilus influenzae produces fever, cough, purulent sputum, dyspnea, and either bronchopneumonia or lobar Pneumonia .[histopathology-india.net]
  • The onset is often sudden with sore throat, fever, dyspnea progressing to dysphagia, pooling of oral secretions, and drooling.[infectiousdiseaseadvisor.com]
Sputum Production
  • Exacerbations of chronic bronchitis (treat if there is increased sputum production, purulent sputum or dyspnoea): treat for five days (longer in severely ill patients) with amoxicillin, tetracycline or clarithromycin; some H. influenzae strains are tetracycline-resistant[patient.info]
  • production Hib pericarditis: Fever, respiratory distress, and tachycardia Septic arthritis: Joint pain, swelling, and decreased mobility Occult bacteremia: Fever, anorexia, and lethargy Underlying medical conditions (especially with invasive Hib disease[emedicine.medscape.com]
Productive Cough
  • The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia.[ncbi.nlm.nih.gov]
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
Fever
  • 517 CommunityAcquired Pneumonia Due to Nonfermenting GramNegative Bacilli 531 Miscellaneous Bacterial Causes of CommunityAcquired Pneumonia 541 Listeria 555 Q Fever 571 Acute Q Fever Treatment 585 Parainfluenza Viruses 602 Respiratory Syncytial Virus[books.google.com]
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
Chills
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • Symptoms of pneumonia usually include: Fever Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness 4. Bacteremia: An infection of the blood.[thevaccinemom.com]
  • Fever and chills. Headache. Tiredness - excessive. Cough. Difficulty breathing or shortness of breath. Anxiety. Nausea. Symptoms can appear quickly and worsen quickly in children, so urgent medical attention is necessary.[mydr.com.au]
  • If you have a baby who is sick with sudden fever, shaking/chills, cough, shortness of breath, chest pain, stiff neck, disorientation and sensitivity to light take action immediately.[healthnavigator.org.nz]
  • Symptoms of pneumonia usually include: [14] Fever (but older people may have lower than normal body temperature) Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness Nails may[en.wikipedia.org]
Intravenous Drugs
  • Ten of the patients were intravenous drug users and were in different stages of HIV disease.[ncbi.nlm.nih.gov]
  • Thirty-four cases occurred in young adults (mean age 33.9 years) with AIDS risk factors, including 23 (67 percent) intravenous drug abusers, six (18 percent) homosexual men, and five (15 percent) with both risks.[ncbi.nlm.nih.gov]
Chest Pain
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • The main symptoms were fever (100%), cough (96.2%), purulent sputum (57.7%), dyspnea (53.8%), and chest pain (38.5%). Hemoptysis was present in 7.7% of patients. Median duration of symptoms before admission was 6 days (range, 1–30 days).[academic.oup.com]
  • Symptoms of pneumonia usually include: Fever Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness 4. Bacteremia: An infection of the blood.[thevaccinemom.com]
Neglect
  • Recurrent, protracted and persistent lower respiratory tract infection: a neglected clinical entity. J Inf Secur. 2015;71:S106–11. . Google Scholar Knoll MD, Moïsi JC, Muhib FB, Wonodi CB, Lee EH, Grant L, et al.[pneumonia.biomedcentral.com]

Workup

  • […] presence of cellulitis Joint, lung, and sinus aspiration Transtracheal aspiration Tympanocentesis Pericardiocentesis Laparoscopy and tubal cultures in women: For suspected NTHi Culdocentesis and peritoneal fluid cultures in women: For suspected NTHi See Workup[emedicine.medscape.com]
Pulmonary Infiltrate
  • When the patient had previously experienced ALI/ARDS, an improvement of pulmonary gas exchanges (Pao 2 /Fio 2 300) and a resolution of pulmonary infiltration on chest radiograph or computed tomography scan during at least 48 h were mandated before the[anesthesiology.pubs.asahq.org]
  • The patients were considered to have definite bacterial pneumonia if they met all of the following 3 criteria: (1) fever (temperature 38 C), cough, and/or expectoration; (2) new pulmonary infiltrate evident on a chest radiograph, for which other, noninfectious[academic.oup.com]
Penicillium
  • Respiratory Syncytial Virus Pneumonia 617 Measles and Varicella Pneumonia 629 Hantavirus Pulmonary Syndrome 643 Case 2 656 Herpes Simplex Pneumonia 671 CommunityAcquired Fungal Diseases 679 Blastomycosis 689 Coccidioidomycosis 695 Cryptococcal Pneumonia 702 Penicillium[books.google.com]
Blood Culture Positive
  • culture Positive upper respiratory culture does not necessarily establish organism as pathogen due to colonization Cellulitis Wound culture Consider CBC, depending on clinical severity Meningitis CBC Spinal tap with cerebrospinal fluid (CSF) culture[arupconsult.com]

Treatment

  • The patient was cured when chloramphenicol treatment was substituted for ampicillin.[ncbi.nlm.nih.gov]
  • Two patients had beta-lactamase producing isolates, one of whom developed an empyema, following treatment with ampicillin, which required surgical drainage.[ncbi.nlm.nih.gov]
  • She was commenced on immunoglobulin replacement following treatment of sepsis and remains well 18 months after the initial presentation.[ncbi.nlm.nih.gov]

Prognosis

  • With appropriate therapy, the prognosis for patients with H influenzae pneumonia appears to be good.[ncbi.nlm.nih.gov]
  • The objective of this study was to determine the epidemiological, clinical, and radiological characteristics of and the prognosis for H. influenzae pneumonia in adults infected with HIV.[academic.oup.com]
  • Treatment and prognosis Mortality rates in patients with H. influenzae pneumonia have been reported as ranging around 10-42% Promoted articles (advertising)[radiopaedia.org]
  • Prognosis The sequelae following Hib meningitis may include deafness, convulsions and intellectual impairment.[patient.info]

Etiology

  • Although Haemophilus influenzae is a common etiologic agent of pneumonia in patients infected with human immunodeficiency virus (HIV), the characteristics of this pneumonia have not been adequately assessed.[ncbi.nlm.nih.gov]
  • With a reference standard of sputum culture and/or serology against the patient's own nasopharyngeal isolate, H. influenzae etiology was detected in 20 patients.[ncbi.nlm.nih.gov]
  • Applicable To Bronchopneumonia due to H. influenzae Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10data.com]

Epidemiology

  • 164 Chapter 11 179 Intensive Care Unit Management of Pneumonia 193 Providing Palliative Care 213 Influenza and Pneumococcal Vaccines 221 Chapter 15 234 Treatment 249 Clinical Manifestations 263 Followup Chest Radiographs 277 Epidemiology of Pneumonia[books.google.com]
  • The epidemiologic and clinical findings indicate that patients without a prior antimicrobial treatment have increased susceptibility to infections of the airway by H influenzae.[ncbi.nlm.nih.gov]
  • Epidemiology and etiology of childhood pneumonia . Bulletin of the World Health Organization . 2008 ; 86 ( 5 ): 408 - 416 . 6. O’Brien , KL , Wolfson , LJ , Watt , JP , et al .[cambridge.org]
  • Table 1 Epidemiological, clinical, and radiological characteristics of HIV-infected patients with Haemophilus influenzae pneumonia and outcome according to clinical presentation.[academic.oup.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The nomenclature ( Haemophilus is Greek for "blood loving") acknowledges the fact that H influenzae requires 2 erythrocyte factors for growth: X (hemin) and V (nicotinamide-adenine-dinucleotide).[emedicine.medscape.com]

Prevention

  • Preventing pneumonia is always better than treating it. Vaccines are available to prevent pneumococcal pneumonia and the flu. Other preventive measures include washing your hands frequently and not smoking.[icdlist.com]
  • Vaccines for both of these pathogens are available to prevent pneumonia.[cambridge.org]
  • Yet the admission rates to hospital, length of stay, investigations, antimicrobial therapy and prevention strategies vary greatly from one geographic area to the next, and the scientific basis for many of our management strategies for pneumonia is weak[books.google.com]
  • How can haemophilus influenzae be prevented? The Hib vaccine can prevent most serious cases of H flu disease. Those in close contact with people with serious H flu disease should receive preventive antibiotics.[drgreene.com]

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