Presentation
Its clinical presentation has been described as being similar to that seen in non-immunosuppressed hosts but clearly different to that of opportunistic pneumonias. An atypical presentation has rarely been seen. [ncbi.nlm.nih.gov]
Patients with bronchopneumonia can present with constitutional symptoms, tachypnea, and a mild fever. Haemophilus influenzae more commonly presents as a bronchopneumonia. [visualdx.com]
The clinical presentation was considered acute if the symptoms before admission lasted ≤7 days; otherwise, the presentation was considered subacute. [academic.oup.com]
Bacteraemic pneumonia was the most common presentation ( n = 99, 46%). Bacteraemic pneumonia was also the most common (47%) presentation in a Canadian study [ 10 ]. [pneumonia.biomedcentral.com]
Entire Body System
- Fever
Symptoms include fever, cough, and shortness of breath. Symptoms may differ depending on the type of pneumonia (either segmental or bronchopneumonia). [visualdx.com]
517 CommunityAcquired Pneumonia Due to Nonfermenting GramNegative Bacilli 531 Miscellaneous Bacterial Causes of CommunityAcquired Pneumonia 541 Listeria 555 Q Fever 571 Acute Q Fever Treatment 585 Parainfluenza Viruses 602 Respiratory Syncytial Virus [books.google.com]
Meningitis - fever, headache, stiff neck, nausea, vomiting and drowsiness Epiglottitis - difficulty breathing and swallowing, pale colour and fever Pneumonia - shortness of breath, fever, lack of energy, loss of appetite, headache, chest pain and cough [health.nsw.gov.au]
Infection of lung by Haemophilus influenzae produces fever, cough, purulent sputum, dyspnea, and either bronchopneumonia or lobar Pneumonia. [histopathology-india.net]
- Pain
Osteomyelitis - swelling, inflammation and pain over the affected bone. How is it spread? Hib bacteria can live harmlessly in the throat of healthy people. [health.nsw.gov.au]
Symptoms of pneumonia usually include: Fever Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness 4. Bacteremia: An infection of the blood. [thevaccinemom.com]
The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent). [ncbi.nlm.nih.gov]
In children older than 2 years, there may be additional symptoms such as a headache, a stiff neck, and back pain. [healthychildren.org]
- Asymptomatic
However, most of the time, H. influenzae are spread by people who have the bacteria in their noses and throats but who are not ill and do not show symptoms (asymptomatic). [health.hawaii.gov]
A small proportion of children (0.5-3%) children will have asymptomatic infections. Meningitis may begin as minor upper respiratory infection(3). [msdsonline.com]
Reservoir of Haemophilus influenzae Humans are the reservoir, via asymptomatic carriage, most commonly in young children. Mode of transmission of Haemophilus influenzae Hib is transmitted from person to person through respiratory droplet spread. [www2.health.vic.gov.au]
A small proportion of children (0.5-3%) children will have asymptomatic infections. Meningitis may begin as minor upper respiratory infection ( Footnote 3 ). [canada.ca]
- Chills
Symptoms of pneumonia usually include: Fever Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness 4. Bacteremia: An infection of the blood. [thevaccinemom.com]
See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after [icdlist.com]
Pneumonia (lung infection) symptoms: Fever and chills Cough Shortness of breath or difficulty breathing Sweating Chest pain Headache Muscle pain or aches Excessive tiredness Bacteremia (blood infection) symptoms: Fever and chills Excessive tiredness Pain [health.hawaii.gov]
Fever and chills. Headache. Tiredness - excessive. Cough. Difficulty breathing or shortness of breath. Anxiety. Nausea. Symptoms can appear quickly and worsen quickly in children, so urgent medical attention is necessary. [mydr.com.au]
If you have a baby who is sick with sudden fever, shaking/chills, cough, shortness of breath, chest pain, stiff neck, disorientation and sensitivity to light take action immediately. [healthnavigator.org.nz]
- Hypothermia
Very severely ill infants may be unable to feed or drink and may also experience unconsciousness, hypothermia and convulsions. [who.int]
Pneumonia was considered when a new infiltrate on a chest radiograph plus one or more of the following symptoms were detected: fever or hypothermia, new cough, pleuritic chest pain, dyspnea or altered breath sounds on auscultation [8]. [journals.plos.org]
Respiratoric
- Cough
Pneumonia caused by Hib does not much differ from ordinary pneumonia and is often accompanied by coughing, chest tightness, coughing up phlegm and fever. [klmhealthservices.com]
See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after [icdlist.com]
The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia. [ncbi.nlm.nih.gov]
Nighttime cough Occasional daytime cough Swelling around the eyes Usually do not complain of headaches if less than 5 years of age Older children: Runny nose or cold symptoms that last longer than 10 days Post nasal drip (nasal drainage that travels down [chop.edu]
- Dyspnea
The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent). [ncbi.nlm.nih.gov]
Infection of lung by Haemophilus influenzae produces fever, cough, purulent sputum, dyspnea, and either bronchopneumonia or lobar Pneumonia. [histopathology-india.net]
In our study, cases basically involved a typical form of presentation, with cough, purulent expectoration, and dyspnea. [academic.oup.com]
The onset is often sudden with sore throat, fever, dyspnea progressing to dysphagia, pooling of oral secretions, and drooling. [infectiousdiseaseadvisor.com]
- Tachypnea
Patients with bronchopneumonia can present with constitutional symptoms, tachypnea, and a mild fever. Haemophilus influenzae more commonly presents as a bronchopneumonia. [visualdx.com]
Fever, dysphagia, accumulation of oropharyngeal secretions, tachypnea and retraction precede obstruction of airways. The epiglottis is swollen by edema, neutrophils, and macrophages. [histopathology-india.net]
The Pneumococcal Vaccines Accelerated Development and Introduction Plan (Pneumo-ADIP) developed a case definition for childhood pneumonia, based on cough, respiratory difficulty and tachypnea [ 5 ] and its use would provide standardization across different [pneumonia.biomedcentral.com]
A child was diagnosed as having pneumonia if he or she had fever, cough, tachypnea, and/or a chest radiograph showing infiltrates. [scielosp.org]
- Productive Cough
The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia. [ncbi.nlm.nih.gov]
Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins. [livestrong.com]
Palavras-chave: Infecções respiratórias Imunodeficiência Timoma Full Text Case history A 70-year-old woman presented to our medical assessment unit with a 4-week history of breathlessness, productive cough, weight loss and lethargy. [journalpulmonology.org]
- Sputum Production
Exacerbations of chronic bronchitis (treat if there is increased sputum production, purulent sputum or dyspnoea): treat for five days (longer in severely ill patients) with amoxicillin, tetracycline or clarithromycin; some H. influenzae strains are tetracycline-resistant [patient.info]
production Hib pericarditis: Fever, respiratory distress, and tachycardia Septic arthritis: Joint pain, swelling, and decreased mobility Occult bacteremia: Fever, anorexia, and lethargy Underlying medical conditions (especially with invasive Hib disease [emedicine.medscape.com]
Gastrointestinal
- Vomiting
They usually will eat less, may be vomiting, and have poor reflexes. 2. Epiglottitis: A life-threatening infection of the throat. 3. Pneumonia: Occurs when the lungs become infected and swell. [thevaccinemom.com]
Side effects can include diarrhea, headache, stomach upset and vomiting. Patients who are allergic to penicillin should not take these medications. [livestrong.com]
Diarrhea Anxiety Shortness of breath or difficulty breathing Altered mental status (confusion) Meningitis (infection of the covering of the brain and spinal cord) symptoms: Fever Headache Stiff neck Nausea with or without vomiting Increased sensitivity [health.hawaii.gov]
Symptoms include headaches, a stiff neck, vomiting, fever and drowsiness. Pneumonia caused by Hib does not much differ from ordinary pneumonia and is often accompanied by coughing, chest tightness, coughing up phlegm and fever. [klmhealthservices.com]
Symptoms may include: Unusual irritability Difficulty sleeping or staying asleep Tugging or pulling at one or both ears Fever Fluid draining from ear(s) Loss of balance Hearing difficulties Ear pain Nausea and vomiting Decreased appetite Nasal congestion [chop.edu]
- Nausea
It can cause symptoms such as: Fever Chills Excessive tiredness Pain in the belly Nausea Vomiting Diarrhea Anxiety Shortness of breath Confusion 5. Cellulitis: An infection of the skin. 6. Arthritis: An infection of the joints. 7. [thevaccinemom.com]
Diarrhea, stomach upset and nausea are side effects of the cephalosporins. Fluoroquinolones Drug resistance is an ever-present problem in the treatment of bacterial infections. [livestrong.com]
[…] with or without vomiting Diarrhea Anxiety Shortness of breath or difficulty breathing Altered mental status (confusion) Meningitis (infection of the covering of the brain and spinal cord) symptoms: Fever Headache Stiff neck Nausea with or without vomiting [health.hawaii.gov]
Symptoms may include: Unusual irritability Difficulty sleeping or staying asleep Tugging or pulling at one or both ears Fever Fluid draining from ear(s) Loss of balance Hearing difficulties Ear pain Nausea and vomiting Decreased appetite Nasal congestion [chop.edu]
Cardiovascular
- Chest Pain
The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent). [ncbi.nlm.nih.gov]
Patients with a segmental pneumonia can present with abrupt onset of fever, pleuritic chest pain, and sore throat. These patients tend to develop bacteremia more frequently than those with bronchopneumonia. [visualdx.com]
See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after [icdlist.com]
Meningitis - fever, headache, stiff neck, nausea, vomiting and drowsiness Epiglottitis - difficulty breathing and swallowing, pale colour and fever Pneumonia - shortness of breath, fever, lack of energy, loss of appetite, headache, chest pain and cough [health.nsw.gov.au]
- Heart Disease
Comorbid conditions were present in 97% of patients, with COPD being the most frequent underlying disease (28.3%), followed by chronic heart disease (18.5%), malignancy (15.2%), diabetes mellitus (13%) and chronic renal failure (4.3%). [journals.plos.org]
Only 8 (7.3%), including 5 born prematurely, had comorbidities: congenital diaphragmatic hernia (n = 2), severe hypoxic-ischemic encephalopathy (n = 2), autosomal polycystic kidney disease (n = 1), congenital heart disease (n = 1), hypothyroidism (n = [cid.oxfordjournals.org]
Workup
[…] presence of cellulitis Joint, lung, and sinus aspiration Transtracheal aspiration Tympanocentesis Pericardiocentesis Laparoscopy and tubal cultures in women: For suspected NTHi Culdocentesis and peritoneal fluid cultures in women: For suspected NTHi See Workup [emedicine.medscape.com]
X-Ray
- Pulmonary Infiltrate
When the patient had previously experienced ALI/ARDS, an improvement of pulmonary gas exchanges (Pao 2 /Fio 2 > 300) and a resolution of pulmonary infiltration on chest radiograph or computed tomography scan during at least 48 h were mandated before the [anesthesiology.pubs.asahq.org]
The patients were considered to have definite bacterial pneumonia if they met all of the following 3 criteria: (1) fever (temperature >38°C), cough, and/or expectoration; (2) new pulmonary infiltrate evident on a chest radiograph, for which other, noninfectious [academic.oup.com]
Microbiology
- Blood Culture Positive
blood culture Positive upper respiratory culture does not necessarily establish organism as pathogen due to colonization Cellulitis Wound culture Consider CBC, depending on clinical severity Meningitis CBC Spinal tap with cerebrospinal fluid (CSF) culture [arupconsult.com]
Among 11 DBS with positive detection of Hib DNA, 10 of them were negative by blood culture and one yielded positive for S. pneumoniae. [journals.plos.org]
Treatment
The primary end point of the study was an early clinical response ‑ clinical stability by day 4 of treatment. The secondary end point was clinical cure anywhere at day 14. [mdedge.com]
The patient was cured when chloramphenicol treatment was substituted for ampicillin. [ncbi.nlm.nih.gov]
Recommendations for treatment of childhood non-severe pneumonia. The Lancet Infectious Diseases2009; 9 (3): 185- 196 Links: clinical features radiological appearance of haemophilus pneumonia treatment of haemophilus pneumonia [gpnotebook.co.uk]
Prognosis
With appropriate therapy, the prognosis for patients with H influenzae pneumonia appears to be good. [ncbi.nlm.nih.gov]
With appropriate therapy, the prognosis for patients with H influenzae pneumonia appears to be good. ( JAMA 238:319-321, 1977) [jamanetwork.com]
Treatment and prognosis Mortality rates in patients with H. influenzae pneumonia have been reported as ranging around 10-42% Promoted articles (advertising) [radiopaedia.org]
The most significant indicator of prognosis is the completeness of surgical resection. Advanced stage tumors may need combination radiotherapy with or without chemotherapy. [journalpulmonology.org]
The objective of this study was to determine the epidemiological, clinical, and radiological characteristics of and the prognosis for H. influenzae pneumonia in adults infected with HIV. [academic.oup.com]
Etiology
Applicable To Bronchopneumonia due to H. influenzae Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]
However, in the last 5 years in our hospital Haemophilus influenzae was the most common etiology. Cases were not considered to be of bacterial etiology unless there was a positive culture from blood or body tissue such as pleural fluid or CSF. [nature.com]
Abstract Although Haemophilus influenzae is a common etiologic agent of pneumonia in patients infected with human immunodeficiency virus (HIV), the characteristics of this pneumonia have not been adequately assessed. [ncbi.nlm.nih.gov]
Epidemiology
164 Chapter 11 179 Intensive Care Unit Management of Pneumonia 193 Providing Palliative Care 213 Influenza and Pneumococcal Vaccines 221 Chapter 15 234 Treatment 249 Clinical Manifestations 263 Followup Chest Radiographs 277 Epidemiology of Pneumonia [books.google.com]
The epidemiologic and clinical findings indicate that patients without a prior antimicrobial treatment have increased susceptibility to infections of the airway by H influenzae. [ncbi.nlm.nih.gov]
An epidemiologic study with special reference to day-care centers. JAMA 1984; 252(18):2581-2584. Shapiro ED, Ward JI. The epidemiology and prevention of disease caused by Haemophilus influenzae type b. Epidemiol Rev 1991; 13:113-142.Tsang R. [ecdc.europa.eu]
Epidemiology and etiology of childhood pneumonia. Bulletin of the World Health Organization. 2008 ; 86 ( 5 ): 408 - 416. 6. O’Brien, KL, Wolfson, LJ, Watt, JP, et al. [cambridge.org]
Pathophysiology
Pathophysiology The nomenclature ( Haemophilus is Greek for "blood loving") acknowledges the fact that H influenzae requires 2 erythrocyte factors for growth: X (hemin) and V (nicotinamide-adenine-dinucleotide). [emedicine.medscape.com]
Prevention
Preventing pneumonia is always better than treating it. Vaccines are available to prevent pneumococcal pneumonia and the flu. Other preventive measures include washing your hands frequently and not smoking. [icdlist.com]
Vaccines for both of these pathogens are available to prevent pneumonia. [cambridge.org]
Pneumonia prevention during a humanitarian emergency: Cost-effectiveness of Haemophilus Influenzae Type B conjugate vaccine and pneumococcal conjugate vaccine in Somalia. Prehospital and Disaster Medicine. 2015; 30(4): 402-11. [immunizationevidence.org]
Prevention Preventing pneumonia in children is an essential component of a strategy to reduce child mortality. Immunization against Hib, pneumococcus, measles and whooping cough (pertussis) is the most effective way to prevent pneumonia. [who.int]
The vaccine’s results for preventing pneumonia were more measured. [path.org]