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Haemophilus Influenzae Pneumonia

Pneumonia Hemophilus Influenza


Presentation

  • Its clinical presentation has been described as being similar to that seen in non-immunosuppressed hosts but clearly different to that of opportunistic pneumonias. An atypical presentation has rarely been seen.[ncbi.nlm.nih.gov]
Fever
  • Symptoms include fever, cough, and shortness of breath. Symptoms may differ depending on the type of pneumonia (either segmental or bronchopneumonia).[visualdx.com]
  • 517 CommunityAcquired Pneumonia Due to Nonfermenting GramNegative Bacilli 531 Miscellaneous Bacterial Causes of CommunityAcquired Pneumonia 541 Listeria 555 Q Fever 571 Acute Q Fever Treatment 585 Parainfluenza Viruses 602 Respiratory Syncytial Virus[books.google.ro]
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
Pain
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • Patients with a segmental pneumonia can present with abrupt onset of fever, pleuritic chest pain, and sore throat. These patients tend to develop bacteremia more frequently than those with bronchopneumonia.[visualdx.com]
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • Symptoms of pneumonia usually include: Fever Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness 4. Bacteremia: An infection of the blood.[thevaccinemom.com]
  • There is fever, heat, erythema, swelling, pain on movement, and decreased movement. The diagnosis is made by culturing Haemophilus influenzae from the joint fluid.[histopathology-india.net]
Chills
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • Symptoms of pneumonia usually include: Fever Cough Shortness of breath Chills Sweating Chest pain that comes and goes with breathing Headache Muscle pain Excessive tiredness 4. Bacteremia: An infection of the blood.[thevaccinemom.com]
  • Pneumonia (lung infection) symptoms: Fever and chills Cough Shortness of breath or difficulty breathing Sweating Chest pain Headache Muscle pain or aches Excessive tiredness Bacteremia (blood infection) symptoms: Fever and chills Excessive tiredness Pain[health.hawaii.gov]
  • Fever and chills. Headache. Tiredness - excessive. Cough. Difficulty breathing or shortness of breath. Anxiety. Nausea. Symptoms can appear quickly and worsen quickly in children, so urgent medical attention is necessary.[mydr.com.au]
Intravenous Drugs
  • Ten of the patients were intravenous drug users and were in different stages of HIV disease.[ncbi.nlm.nih.gov]
Hypoxemia
  • There was no association between death and the grade of immunosuppression, dyspnea, hypoxemia, bilateral radiological involvement, radiological progression within the first 72 h of treatment, cavitation, polymicrobial etiology of pneumonia, bacteremia[academic.oup.com]
Cough
  • The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia.[ncbi.nlm.nih.gov]
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • Symptoms include fever, cough, and shortness of breath. Symptoms may differ depending on the type of pneumonia (either segmental or bronchopneumonia).[visualdx.com]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
Dyspnea
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • In our study, cases basically involved a typical form of presentation, with cough, purulent expectoration, and dyspnea.[academic.oup.com]
  • Infection of lung by Haemophilus influenzae produces fever, cough, purulent sputum, dyspnea, and either bronchopneumonia or lobar Pneumonia.[histopathology-india.net]
  • It usually presents in the 4th or 5th decade of life with symptoms due to thymoma, including cough, dysphagia, dyspnea or hoarseness of voice or related to associated infections (as noted in the case presented), the most common being recurrent sinopulmonary[journalpulmonology.org]
  • The onset is often sudden with sore throat, fever, dyspnea progressing to dysphagia, pooling of oral secretions, and drooling.[infectiousdiseaseadvisor.com]
Productive Cough
  • The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia.[ncbi.nlm.nih.gov]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
  • Palavras-chave: Infecções respiratórias Imunodeficiência Timoma Full Text Case history A 70-year-old woman presented to our medical assessment unit with a 4-week history of breathlessness, productive cough, weight loss and lethargy.[journalpulmonology.org]
Tachypnea
  • Patients with bronchopneumonia can present with constitutional symptoms, tachypnea, and a mild fever. Haemophilus influenzae more commonly presents as a bronchopneumonia.[visualdx.com]
  • Fever, dysphagia, accumulation of oropharyngeal secretions, tachypnea and retraction precede obstruction of airways. The epiglottis is swollen by edema, neutrophils, and macrophages.[histopathology-india.net]
  • The Pneumococcal Vaccines Accelerated Development and Introduction Plan (Pneumo-ADIP) developed a case definition for childhood pneumonia, based on cough, respiratory difficulty and tachypnea [ 5 ] and its use would provide standardization across different[pneumonia.biomedcentral.com]
  • A child was diagnosed as having pneumonia if he or she had fever, cough, tachypnea, and/or a chest radiograph showing infiltrates.[scielosp.org]
Productive Cough
  • The clinical picture was characterized by a prolonged course (median 4 weeks), non-productive cough, dyspnoea, and absence of findings usually present in bacterial pneumonia.[ncbi.nlm.nih.gov]
  • Symptoms of H. flu pneumonia are fever, productive cough and shortness of breath. Treatment consists of third-generation cephalosporins, fluoroquinolones and beta-lactam pencillins.[livestrong.com]
  • Palavras-chave: Infecções respiratórias Imunodeficiência Timoma Full Text Case history A 70-year-old woman presented to our medical assessment unit with a 4-week history of breathlessness, productive cough, weight loss and lethargy.[journalpulmonology.org]
Chest Pain
  • The common presenting symptoms in young adult patients with H. influenzae pneumonia were fever (100 percent), productive cough (100 percent), chest pain (53 percent), and dyspnea (47 percent).[ncbi.nlm.nih.gov]
  • Patients with a segmental pneumonia can present with abrupt onset of fever, pleuritic chest pain, and sore throat. These patients tend to develop bacteremia more frequently than those with bronchopneumonia.[visualdx.com]
  • See your doctor promptly if you Have a high fever Have shaking chills Have a cough with phlegm that doesn't improve or gets worse Develop shortness of breath with normal daily activities Have chest pain when you breathe or cough Feel suddenly worse after[icdlist.com]
  • There was no history of chest pain, wheeze or hemoptysis. She had been recently treated with amoxicillin for a lower respiratory tract infection.[journalpulmonology.org]
  • Meningitis - fever, headache, stiff neck, nausea, vomiting and drowsiness Epiglottitis - difficulty breathing and swallowing, pale colour and fever Pneumonia - shortness of breath, fever, lack of energy, loss of appetite, headache, chest pain and cough[health.nsw.gov.au]
Neglect
  • Recurrent, protracted and persistent lower respiratory tract infection: a neglected clinical entity. J Inf Secur. 2015;71:S106–11. . Google Scholar Knoll MD, Moïsi JC, Muhib FB, Wonodi CB, Lee EH, Grant L, et al.[pneumonia.biomedcentral.com]

Workup

  • […] presence of cellulitis Joint, lung, and sinus aspiration Transtracheal aspiration Tympanocentesis Pericardiocentesis Laparoscopy and tubal cultures in women: For suspected NTHi Culdocentesis and peritoneal fluid cultures in women: For suspected NTHi See Workup[emedicine.medscape.com]
Pulmonary Infiltrate
  • When the patient had previously experienced ALI/ARDS, an improvement of pulmonary gas exchanges (Pao 2 /Fio 2 300) and a resolution of pulmonary infiltration on chest radiograph or computed tomography scan during at least 48 h were mandated before the[anesthesiology.pubs.asahq.org]
  • The patients were considered to have definite bacterial pneumonia if they met all of the following 3 criteria: (1) fever (temperature 38 C), cough, and/or expectoration; (2) new pulmonary infiltrate evident on a chest radiograph, for which other, noninfectious[academic.oup.com]
Blood Culture Positive
  • culture Positive upper respiratory culture does not necessarily establish organism as pathogen due to colonization Cellulitis Wound culture Consider CBC, depending on clinical severity Meningitis CBC Spinal tap with cerebrospinal fluid (CSF) culture[arupconsult.com]
  • Díez-Padrisa N, Bassat Q, Morais L, O’Callaghan-Gordo C, Machevo S et al. (2012) Procalcitonin and C-reactive protein as predictors of blood culture positivity among hospitalised children with severe pneumonia in Mozambique.[journals.plos.org]

Treatment

  • The patient was cured when chloramphenicol treatment was substituted for ampicillin.[ncbi.nlm.nih.gov]

Prognosis

  • With appropriate therapy, the prognosis for patients with H influenzae pneumonia appears to be good.[ncbi.nlm.nih.gov]
  • With appropriate therapy, the prognosis for patients with H influenzae pneumonia appears to be good. ( JAMA 238:319-321, 1977)[jamanetwork.com]
  • The most significant indicator of prognosis is the completeness of surgical resection. Advanced stage tumors may need combination radiotherapy with or without chemotherapy.[journalpulmonology.org]
  • The objective of this study was to determine the epidemiological, clinical, and radiological characteristics of and the prognosis for H. influenzae pneumonia in adults infected with HIV.[academic.oup.com]
  • Treatment and prognosis Mortality rates in patients with H. influenzae pneumonia have been reported as ranging around 10-42% Promoted articles (advertising)[radiopaedia.org]

Etiology

  • Abstract Although Haemophilus influenzae is a common etiologic agent of pneumonia in patients infected with human immunodeficiency virus (HIV), the characteristics of this pneumonia have not been adequately assessed.[ncbi.nlm.nih.gov]
  • However, in the last 5 years in our hospital Haemophilus influenzae was the most common etiology. Cases were not considered to be of bacterial etiology unless there was a positive culture from blood or body tissue such as pleural fluid or CSF.[nature.com]

Epidemiology

  • 164 Chapter 11 179 Intensive Care Unit Management of Pneumonia 193 Providing Palliative Care 213 Influenza and Pneumococcal Vaccines 221 Chapter 15 234 Treatment 249 Clinical Manifestations 263 Followup Chest Radiographs 277 Epidemiology of Pneumonia[books.google.com]
  • The epidemiologic and clinical findings indicate that patients without a prior antimicrobial treatment have increased susceptibility to infections of the airway by H influenzae.[ncbi.nlm.nih.gov]
  • Epidemiology and etiology of childhood pneumonia. Bulletin of the World Health Organization. 2008 ; 86 ( 5 ): 408 - 416. 6. O’Brien, KL, Wolfson, LJ, Watt, JP, et al.[cambridge.org]
  • Table 1 Epidemiological, clinical, and radiological characteristics of HIV-infected patients with Haemophilus influenzae pneumonia and outcome according to clinical presentation.[academic.oup.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The nomenclature ( Haemophilus is Greek for "blood loving") acknowledges the fact that H influenzae requires 2 erythrocyte factors for growth: X (hemin) and V (nicotinamide-adenine-dinucleotide).[emedicine.medscape.com]

Prevention

  • Preventing pneumonia is always better than treating it. Vaccines are available to prevent pneumococcal pneumonia and the flu. Other preventive measures include washing your hands frequently and not smoking.[icdlist.com]
  • Vaccines for both of these pathogens are available to prevent pneumonia.[cambridge.org]
  • Pneumonia prevention during a humanitarian emergency: Cost-effectiveness of Haemophilus Influenzae Type B conjugate vaccine and pneumococcal conjugate vaccine in Somalia. Prehospital and Disaster Medicine. 2015; 30(4): 402-11.[immunizationevidence.org]
  • If so, Hib conjugate vaccines would play little role in the prevention of pneumonia. In two prospective series of children hospitalized for pneumonia in China, the causative agents were searched for with a wide panel of microbiologic assays.[insights.ovid.com]
  • Conjugate Hib and S. pneumoniae vaccines could prevent many of the serious infections resulting in hospitalization of Guatemalan children (6, 9, 13, 22–25).[scielosp.org]

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