[…] early 1920s of the greatest influenza pandemic in history, direct encounters with FM1 virus at Fort Mon mouth in 1947, the care of influenza patients in the 1950s, the pursuit of the in fluenza virus through the modern pandemics of 1957 and 1968, and a present [books.google.com]

Within a few hours her mother presented to the same hospital with similar, but less severe symptoms. Both women were treated and are expected to make full recoveries. No additional cases have occurred. [thedetectologist.blogspot.com]

A frequent presenter at national conferences on the topic of periodization, Haff was invited to present his research on the periodization of strength training in the United Kingdom in 2008. [pravaliacucarti.ro]

• Episodic Weakness

  Weakness 464 Case 73B An African American Man with Hyperthyroidism and Acute Paralysis 470 Case 74 A Boy with Large Muscles Leg Pain and Elevated Serum Creatine Kinase 472 Case 75 A Woman with Proximal Muscle Weakness Calf Hypertrophy Heel Contractures [books.google.com]

• Difficulty Walking

  Walking and Ataxia 415 Case 66 A Man with Progressive Neuropathy and Congestive Heart Failure 422 Case 67 An Elderly Woman with a Progressive Neuropathy 429 Case 68 A Young Woman with Difficulty Swallowing 433 Case 69 A Young Woman with Intermittent [books.google.com]

• Congestive Heart Failure

  Heart Failure 422 Case 67 An Elderly Woman with a Progressive Neuropathy 429 Case 68 A Young Woman with Difficulty Swallowing 433 Case 69 A Young Woman with Intermittent Weakness and a Positive Family History of Similar Problems 436 Case 70 A Woman with [books.google.com]

• Vomiting

  The next day the younger woman, who ate more of the fish, vomited and experienced muscle pain severe enough that she made a visit to a nearby hospital. [thedetectologist.blogspot.com]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  Tendonitis Myofascial pain syndrome Headaches and migraines Postoperative pain Digestive Issues & Nausea Heartburn, Acid Reflux Irritable Bowel Syndrome (IBS) Chronic indigestion Chronic loose stools or constipation Acute and chronic gastritis Nausea and vomiting [acupuncturemaui.com]

  One hour later, the wife vomited. Six hours after the meal, they developed generalized body aches and muscle stiffness. [cdc.gov]

  Some other symptoms that have been reported include nausea, vomiting, chest pain, dyspnea and pain with light touch. [academic.oup.com]

• Nausea

  The syndrome is characterized by the sudden onset of severe rhabdomyolysis with nausea, vomiting, chest pain, shortness of breath, and pain with light touch. In Europe Haff disease has been associated with consumption of burbot, eel, and pike. [thedetectologist.blogspot.com]

  […] foot pain Arm, wrist and hand pain Knee pain Hip pain Carpal tunnel syndrome Tennis Elbow Repetitive strain injuries Jaw pain (TMJ) Sciatica Arthritis Tendonitis Myofascial pain syndrome Headaches and migraines Postoperative pain Digestive Issues & Nausea [acupuncturemaui.com]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  Some other symptoms that have been reported include nausea, vomiting, chest pain, dyspnea and pain with light touch. [academic.oup.com]

  Other characteristic manifestations include bitter/metallic taste in the mouth, weakness, excessive sweating, abdominal cramps, nausea, diarrhea, parasthesia, bradycardia, dark urine, renal failure, cyanosis, and respiratory distress (4,10,11). [apjmt.mums.ac.ir]

• Dysphagia

  […] followed by autonomic changes and hyperthermia.8 In over 80% of cases, rigidity or mental status changes herald the onset of the syndrome.8 Specific early signs include obtundation, catatonia, tachycardia, tachypnea, labile blood pressure, dysarthria, dysphagia [palpath.com]

  LDL] hyperlipoproteinemia (Pure) hypercholesterolemia NOS Hyperchylia gastrica, psychogenic F45.8 ICD-10-CM Diagnosis Code F45.8 Other somatoform disorders 2016 2017 2018 2019 Billable/Specific Code Applicable To Psychogenic dysmenorrhea Psychogenic dysphagia [icd10data.com]

• Food Poisoning

  Food Poisoning. In: Nelson LS, Lewin NA, Howland MA, Hoffman RS, Goldfrank LR, Flomenbaum NE, editors. Goldfrank's Toxicologic Emergencies. 9th ed. New York: McGraw-Hill; 2011. p.668-81. [apjmt.mums.ac.ir]

• Gingival Overgrowth

  overgrowth 60 33 frequent (33%) Frequent (79-30%) HP:0000212 10 blepharophimosis 60 33 frequent (33%) Frequent (79-30%) HP:0000581 11 furrowed tongue 60 33 frequent (33%) Frequent (79-30%) HP:0000221 12 intellectual disability 60 33 occasional (7.5%) [malacards.org]

• Chest Pain

  The syndrome is characterized by the sudden onset of severe rhabdomyolysis with nausea, vomiting, chest pain, shortness of breath, and pain with light touch. In Europe Haff disease has been associated with consumption of burbot, eel, and pike. [thedetectologist.blogspot.com]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  Following discharge, the patient has reported occasional chest pain that he had not noticed before this episode. His wife did not become ill. St. Louis, Missouri Patients 4 and 5. [cdc.gov]

  Some other symptoms that have been reported include nausea, vomiting, chest pain, dyspnea and pain with light touch. [academic.oup.com]

  DISCUSSION Haff disease is a syndrome consisting of unexplained rhabdomyolysis characterized by sudden, extreme muscular rigidity, diffuse myalgia, chest pain, shortness of breath, full-body numbness and weakness, and coffee-colored urine, as well as [ncbi.nlm.nih.gov]

• Diplopia

  An Older Woman with Progressive Muscle Weakness 572 Case 92 An HIVInfected Man with Muscle Weakness and Spasms 577 Case 93 A Woman with Limb Swelling and Pain 581 Case 94 A Man with a Bent Spine 584 Case 95 A Man with Muscle Stiffness and Later with Diplopia [books.google.com]

• Myalgia

  The most common causes of myalgia are overuse, injury or stress [1]. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes. [wikidoc.org]

  The clinical picture presented is compatible with a variant of Epidemic Myalgia Syndrome - usually caused by an Echovirus. Epidemic myalgia is also known as Bornholm's disease. [flutrackers.com]

  Striated muscle damage leads to full-body myalgia, weakness, and muscle rigidity. Carbon dioxide retention and respiratory failure occur due to respiratory muscle weakness. [ncbi.nlm.nih.gov]

  His myalgias lasted for about 10–12 h, and then resolved. CPK and myoglobin started to improve on day 4. [academic.oup.com]

  All of them presented to the emergency department with myalgia. The diagnosis of rhabdomyolysis was supported by an elevated creatine kinase level. All recovered with supportive treatment. [cambridge.org]

• Foot Deformity

  Deformities 510 Case 81 A Woman with Droopy Eyelids and Ophthalmoplegia 515 Case 82 A Man with Weakness and Swelling in the Neck 522 Case 83 A Woman with Muscle Pains and Dark Urine 526 Case 84 A Woman with Progressive Proximal Muscle Weakness 533 Case [books.google.com]

• Proximal Muscle Weakness

  Muscle Weakness 533 Case 85 A Sedentary Man with Acute Respiratory Failure and Myoglobinuria 539 Case 86 A Uremic Man with Proximal Muscle Weakness 545 Case 87 A Woman with Weakness Elevated Cholesterol and Serum Creatine Kinase Levels 550 Case 88 An [books.google.com]

• Calf Hypertrophy

  Hypertrophy Heel Contractures and Elevated Serum Creatine Kinase 480 Case 76 A Young Man with Distal Leg Wasting and Normal Sensation 484 Case 77 A Woman with Droopy Eyelids and Difficulty Swallowing 493 Case 78 A Man with Facial and Shoulder Muscle [books.google.com]

• Bulbous Nose

  nose 60 33 hallmark (90%) Very frequent (99-80%) HP:0000414 8 abnormality of the hand 60 33 hallmark (90%) Very frequent (99-80%) HP:0001155 9 gingival overgrowth 60 33 frequent (33%) Frequent (79-30%) HP:0000212 10 blepharophimosis 60 33 frequent (33% [malacards.org]

• Dark Urine

  […] and Later Contractures 503 Case 80 A Woman with Longstanding Weakness and Foot Deformities 510 Case 81 A Woman with Droopy Eyelids and Ophthalmoplegia 515 Case 82 A Man with Weakness and Swelling in the Neck 522 Case 83 A Woman with Muscle Pains and Dark [books.google.com]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  Eight patients reported dark urine compatible with myoglobinuria and a mild rash was seen in four. [ncbi.nlm.nih.gov]

  The original cases exhibited muscle pains, rigidity, and dark urine. Subsequent outbreaks in the Baltic regions have affected thousands of patients (2,4). Although deaths have been reported, most patients recover without any consequence. [apjmt.mums.ac.ir]

• Paresthesia

  She also described fingertips and peri-oral paresthesias. She denied gastrointestinal symptoms, fever, abdominal pain, flushing, or hot/cold reversal. She was taking no medications. She denied smoking, consuming alcohol, or drug abuse. Figure 1. [apjmt.mums.ac.ir]

  Applicable To Longitudinal reduction deformity of unspecified limb(s) Ectromelia of limb NOS Hemimelia of limb NOS Reduction defect of limb NOS Hemiparalysis - see Hemiplegia Hemiparesis - see Hemiplegia Hemiparesthesia R20.2 ICD-10-CM Diagnosis Code R20.2 Paresthesia [icd10data.com]

• Peripheral Neuropathy

  Neuropathy 405 Case 64 A Man with a Neuropathy Weight Loss and Lung Nodules 411 Case 65 A Woman with Difficulty Walking and Ataxia 415 Case 66 A Man with Progressive Neuropathy and Congestive Heart Failure 422 Case 67 An Elderly Woman with a Progressive [books.google.com]

  neuropathy, Pes anserinus pain syndrome, Stiff man syndrome, Sweet's disease, West nile encephalitis, Western equine encephalitis Nutritional/Metabolic Hypovitaminosis d, Phosphate diabetes, Vitamin d deficiency Obstetric/Gynecologic No underlying causes [wikidoc.org]

• Ataxia

  Arthritis Who Developed Numbness and Pain in the Feet 399 Case 63 A Woman with Granulomatous Lesions in the Lungs and a Peripheral Neuropathy 405 Case 64 A Man with a Neuropathy Weight Loss and Lung Nodules 411 Case 65 A Woman with Difficulty Walking and Ataxia [books.google.com]

  Applicable To Celiac disease with steatorrhea Celiac gluten-sensitive enteropathy Nontropical sprue Code Also exocrine pancreatic insufficiency ( K86.81 ) Use Additional code for associated disorders including: dermatitis herpetiformis ( L13.0 ) gluten ataxia [icd10data.com]

• Foot Drop

  Case 58A A Woman with Leg Numbness Pain Weakness and Slow Nerve Conduction Velocities 372 Case 58B A Boy with Leg Weakness 375 Case 59 A Man with Hand Weakness and Numbness After Skiing 383 Case 60 A Man with Recurrent Foot Drop 386 Case 61 An Elderly [books.google.com]

• Areflexia

  67 An Elderly Woman with a Progressive Neuropathy 429 Case 68 A Young Woman with Difficulty Swallowing 433 Case 69 A Young Woman with Intermittent Weakness and a Positive Family History of Similar Problems 436 Case 70 A Woman with Muscle Weakness and Areflexia [books.google.com]

• Pericardial Effusion

  Effusion & Cardiac Activity. [books.google.com]

  Other cardiovascular abnormalities may include patent ductus arteriosus (PDA) (in 50%), pericardial effusion (20%), and increased vascular tortuosity. [ncbi.nlm.nih.gov]

• Hypercholesterolemia

  Hypercholesterolemia (essential) (primary) (pure) E78.00 ICD-10-CM Diagnosis Code E78.00 Pure hypercholesterolemia, unspecified 2017 - New Code 2018 2019 Billable/Specific Code Applicable To Fredrickson's hyperlipoproteinemia, type IIa Hyperbetalipoproteinemia [icd10data.com]

• Slow Nerve Conduction Velocities

  Case 58A A Woman with Leg Numbness Pain Weakness and Slow Nerve Conduction Velocities 372 Case 58B A Boy with Leg Weakness 375 Case 59 A Man with Hand Weakness and Numbness After Skiing 383 Case 60 A Man with Recurrent Foot Drop 386 Case 61 An Elderly [books.google.com]

• Candida

  Edoarda Vasco de Albuquerque Albuquerque 1, Luciana Pinto Brito 2, Ludmilla Malveira Lima Lopes 1, Andrea Glezer 1, Elisa Del Rosario Ugarte Verduguez 3, Berenice Bilharinho De Mendonça 2, Marcello Delano Bronstein 1, Marcio Carlos Machado 1 and Maria Candida [clindiabetesendo.biomedcentral.com]

Get clear, concise descriptions and evidence-based treatment guidelines for a full range of clinical conditions, ranging from the common to the unusual. [books.google.com]

[…] to alkalize the urine, and other supportive and symptomatic treatments. [ncbi.nlm.nih.gov]

Treatment - Haff disease Treatment consisted of intravenous hydration, with administration of hepatic and stomach protective agents as well as diuretics. [checkorphan.org]

All recovered with supportive treatment. The clinical picture of these 4 patients was compatible with Haff disease. Haff disease is a syndrome in which rhabdomyolysis develops subsequent to consumption of certain cooked seafood. [cambridge.org]

Prognosis - Haff disease Not supplied. Treatment - Haff disease Treatment consisted of intravenous hydration, with administration of hepatic and stomach protective agents as well as diuretics. [checkorphan.org]

Early diagnosis and proper treatment are essential to improving the prognosis for patients with Haff disease. The etiology of Haff disease remains unclear. [ncbi.nlm.nih.gov]

Cases have reported muscle pain and weakness persisting for months, [61] and antidepressant discontinuation may contribute to ongoing features. [62] Following appropriate medical management, serotonin syndrome is generally associated with a favorable prognosis [en.wikipedia.org]

The etiology of the disease is unknown, but the ill fish can be toxic for people. The 1st outbreak of the disease was registered in Gaff [Haff] bay. [zoonosesonline.org]

Because cases may occur outside of endemic areas, fish consumption should be included in the history for any case of rhabomyolysis of unknown etiology. [ingentaconnect.com]

"We already know that it is a virus that causes the disease, but we have not yet determined which type" [is it already known that the etiology is viral? What evidence has already been identified? - Mod RNA], says Dr. [flutrackers.com]

Diagnosis of rhabdomyolysis was made, but the etiology was unknown. He was started on intravenous normal saline at a rate of 200 cc/h, with strict monitoring of urine output. His urine output was maintained around 2–3 ml/kg/h. [academic.oup.com]

Although the etiology was not determined, epidemiologic investigations linked illness to ingestion of fish, especially burbot. The first reported case of Haff disease in the United States occurred in Texas in 1984 (M. [cdc.gov]

Well, for now, without more robust clinical and epidemiological information, there are only hypotheses to be investigated, which should include viruses and toxins ... [flutrackers.com]

The majority of the 15 cases of Haff disease reported here clustered between the epidemiological week 48 and 51 of 2016 [26-30 Dec 2016], however, new cases continued to be reported up to epidemiological week 14 of 2017 [week ending 7 Apr 2017] (Figure [outbreakwatch.blogspot.com]

The majority of the 15 cases of Haff disease reported here clustered between the epidemiological week 48 and 51 of 2016, however, new cases continued to be reported up to epidemiological week 14 of 2017 ( Figure ). [ncbi.nlm.nih.gov]

We present the investigation of an outbreak of Haff disease in Nanjing, Jiangsu Province, China incorporating both epidemiological and chemical analysis. [infona.pl]

The emergence and epidemiology of Haff disease in China. Toxins (Basel) 2016 ; 8 ( 12 ): 359 - 367. 6. Chen, Y, Yuan, B, Xie, G, et al. [cambridge.org]

Implicated drugs, pathophysiology and management". Drug Saf. 13 (2): 94–104. doi : 10.2165/00002018-199513020-00004. PMID 7576268. Frank, Christopher (2008). "Recognition and treatment of serotonin syndrome". Can Fam Physician. 54 : 988–92. [en.wikipedia.org]

Get the skills you need now with new information on global humanitarian relief and expedition medicine, plus expanded coverage of injury prevention and environmental preservation. [books.google.com]

Nanjing 210009, Jiangsu, PR China Guoxiang Xie Nanjing Municipal Center for Disease Control and Prevention, Nanjing 210003, Jiangsu, PR China Shiqi Zhen Institute of Food Safety and Assessment, Jiangsu Provincial Center for Disease Control and Prevention [infona.pl]

Centers for Disease Control and Prevention (CDC) (1998). "Haff disease associated with eating buffalo fish--United States, 1997". MMWR Morb. Mortal. Wkly. Rep. 47 (50): 1091–3. PMID 9883771. [en.wikipedia.org]

When Haff disease is suspected, proper treatment should be initiated as soon as possible to prevent deterioration in the condition of the patient. [ncbi.nlm.nih.gov]