As for the other two patients who presented later than the two sisters, the history of crayfish consumption was sought retrospectively. All patients had normal vital signs. Motor weakness was not present. [cambridge.org]

The present study is the first report of Haff disease complicated by multiple organ failure after crayfish consumption. A 66-year-old Chinese man ate cooked crayfish on the night of June 23, 2013. [ncbi.nlm.nih.gov]

A frequent presenter at national conferences on the topic of periodization, Haff was invited to present his research on the periodization of strength training in the United Kingdom in 2008. [pravaliacucarti.ro]

(a) Patients may present with more than one comorbidity or symptom/signs. (b) Data available for 11 patients. [outbreakwatch.blogspot.com]

• Vomiting

  The next day the younger woman, who ate more of the fish, vomited and experienced muscle pain severe enough that she made a visit to a nearby hospital. [thedetectologist.blogspot.com]

  This is especially important in patients with Haff disease who are vomiting and at risk of dehydration. There is no guideline for the duration of fluid administration. [cambridge.org]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  Tendonitis Myofascial pain syndrome Headaches and migraines Postoperative pain Digestive Issues & Nausea Heartburn, Acid Reflux Irritable Bowel Syndrome (IBS) Chronic indigestion Chronic loose stools or constipation Acute and chronic gastritis Nausea and vomiting [acupuncturemaui.com]

  Symptoms occurred within 3–20 h of seafood ingestion, including myalgia, weakness, and, less frequently, nausea, vomiting, abdominal pain, and diarrhea. Myalgia and muscle weakness should normally subside within 2–3 days. [mdpi.com]

• Nausea

  […] foot pain Arm, wrist and hand pain Knee pain Hip pain Carpal tunnel syndrome Tennis Elbow Repetitive strain injuries Jaw pain (TMJ) Sciatica Arthritis Tendonitis Myofascial pain syndrome Headaches and migraines Postoperative pain Digestive Issues & Nausea [acupuncturemaui.com]

  The syndrome is characterized by the sudden onset of severe rhabdomyolysis with nausea, vomiting, chest pain, shortness of breath, and pain with light touch. In Europe Haff disease has been associated with consumption of burbot, eel, and pike. [thedetectologist.blogspot.com]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  One patient had nausea. Otherwise, gastrointestinal (GI) or constitutional symptoms were absent. The history of crayfish consumption was first elicited from the sisters as they presented to the ED at the same time with similar symptoms. [cambridge.org]

  Symptoms occurred within 3–20 h of seafood ingestion, including myalgia, weakness, and, less frequently, nausea, vomiting, abdominal pain, and diarrhea. Myalgia and muscle weakness should normally subside within 2–3 days. [mdpi.com]

• Food Poisoning

  Previously reported outbreaks of fish-related poisoning have been caused by scromboid, ciguatera, tetrodotoxin poisoning, palytoxin poisoning, mercury contamination, paralytic shellfish poisoning, and amnestic shellfish poisoning (1). [apjmt.mums.ac.ir]

• Chest Pain

  The syndrome is characterized by the sudden onset of severe rhabdomyolysis with nausea, vomiting, chest pain, shortness of breath, and pain with light touch. In Europe Haff disease has been associated with consumption of burbot, eel, and pike. [thedetectologist.blogspot.com]

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  Following discharge, the patient has reported occasional chest pain that he had not noticed before this episode. His wife did not become ill. St. Louis, Missouri Patients 4 and 5. [cdc.gov]

  Light to dark brown-colored urine Nausea Chest pain Vomiting Shortness of breath Profuse sweating Pain to light touch Dry mouth, numbness of thighs or whole body, back pain, and stomach cramps are also reported, but seen less frequently.[13] References [en.wikipedia.org]

  DISCUSSION Haff disease is a syndrome consisting of unexplained rhabdomyolysis characterized by sudden, extreme muscular rigidity, diffuse myalgia, chest pain, shortness of breath, full-body numbness and weakness, and coffee-colored urine, as well as [ncbi.nlm.nih.gov]

• Myalgia

  In cases of Haff disease that develop after eating crayfish, besides myalgia, GI disturbance, e.g., nausea, vomiting, and abdominal pain, may be present.Reference Diaz 2 As evidenced by these four patients, myalgia is the most common presenting clinical [cambridge.org]

  Symptoms occurred within 3–20 h of seafood ingestion, including myalgia, weakness, and, less frequently, nausea, vomiting, abdominal pain, and diarrhea. Myalgia and muscle weakness should normally subside within 2–3 days. [mdpi.com]

  The most common causes of myalgia are overuse, injury or stress [1]. However, myalgia can also be caused by diseases, disorders, medications, as a response to vaccination and withdrawal syndromes. [wikidoc.org]

  Striated muscle damage leads to full-body myalgia, weakness, and muscle rigidity. Carbon dioxide retention and respiratory failure occur due to respiratory muscle weakness. [ncbi.nlm.nih.gov]

  The clinical picture presented is compatible with a variant of Epidemic Myalgia Syndrome - usually caused by an Echovirus. Epidemic myalgia is also known as Bornholm's disease. [flutrackers.com]

• Paresthesia

  She also described fingertips and peri-oral paresthesias. She denied gastrointestinal symptoms, fever, abdominal pain, flushing, or hot/cold reversal. She was taking no medications. She denied smoking, consuming alcohol, or drug abuse. Figure 1. [apjmt.mums.ac.ir]

  Applicable To Longitudinal reduction deformity of unspecified limb(s) Ectromelia of limb NOS Hemimelia of limb NOS Reduction defect of limb NOS Hemiparalysis - see Hemiplegia Hemiparesis - see Hemiplegia Hemiparesthesia R20.2 ICD-10-CM Diagnosis Code R20.2 Paresthesia [icd10data.com]

• Dark Urine

  Symptoms include muscle weakness, pain, dry mouth, chest pain, nausea, vomiting, confusion, and dark urine. Severe symptoms typically resolve quickly though some patients complain of fatigue for months following the onset of the acute symptoms. [fieldandstream.com]

  […] and Later Contractures 503 Case 80 A Woman with Longstanding Weakness and Foot Deformities 510 Case 81 A Woman with Droopy Eyelids and Ophthalmoplegia 515 Case 82 A Man with Weakness and Swelling in the Neck 522 Case 83 A Woman with Muscle Pains and Dark [books.google.com]

  Eight patients reported dark urine compatible with myoglobinuria and a mild rash was seen in four. [ncbi.nlm.nih.gov]

  The original cases exhibited muscle pains, rigidity, and dark urine. Subsequent outbreaks in the Baltic regions have affected thousands of patients (2,4). Although deaths have been reported, most patients recover without any consequence. [apjmt.mums.ac.ir]

[…] to alkalize the urine, and other supportive and symptomatic treatments. [ncbi.nlm.nih.gov]

Get clear, concise descriptions and evidence-based treatment guidelines for a full range of clinical conditions, ranging from the common to the unusual. [books.google.com]

All recovered with supportive treatment. The clinical picture of these 4 patients was compatible with Haff disease. Haff disease is a syndrome in which rhabdomyolysis develops subsequent to consumption of certain cooked seafood. [cambridge.org]

Treatment - Haff disease Treatment consisted of intravenous hydration, with administration of hepatic and stomach protective agents as well as diuretics. [checkorphan.org]

Prognosis - Haff disease Not supplied. Treatment - Haff disease Treatment consisted of intravenous hydration, with administration of hepatic and stomach protective agents as well as diuretics. [checkorphan.org]

Early diagnosis and proper treatment are essential to improving the prognosis for patients with Haff disease. The etiology of Haff disease remains unclear. [ncbi.nlm.nih.gov]

Overall, the prognosis of Haff disease is good. All four patients in this series were discharged from the hospital without any complications. [cambridge.org]

Cases have reported muscle pain and weakness persisting for months, [61] and antidepressant discontinuation may contribute to ongoing features. [62] Following appropriate medical management, serotonin syndrome is generally associated with a favorable prognosis [en.wikipedia.org]

The etiology of the disease is unknown, but the ill fish can be toxic for people. The 1st outbreak of the disease was registered in Gaff [Haff] bay. [zoonosesonline.org]

Because cases may occur outside of endemic areas, fish consumption should be included in the history for any case of rhabomyolysis of unknown etiology. [ingentaconnect.com]

"We already know that it is a virus that causes the disease, but we have not yet determined which type" [is it already known that the etiology is viral? What evidence has already been identified? - Mod RNA], says Dr. [flutrackers.com]

The etiology of Haff disease remains unclear. One possible cause is an unknown heat-stable biological toxin that accumulates in the implicated food, but the toxin has not yet been identified. [ncbi.nlm.nih.gov]

Diagnosis of rhabdomyolysis was made, but the etiology was unknown. He was started on intravenous normal saline at a rate of 200 cc/h, with strict monitoring of urine output. His urine output was maintained around 2–3 ml/kg/h. [academic.oup.com]

In the present review of published case studies and official press releases, the main objective is to report the emergence and epidemiology of Haff disease in China. [mdpi.com]

Well, for now, without more robust clinical and epidemiological information, there are only hypotheses to be investigated, which should include viruses and toxins ... [flutrackers.com]

The majority of the 15 cases of Haff disease reported here clustered between the epidemiological week 48 and 51 of 2016, however, new cases continued to be reported up to epidemiological week 14 of 2017 ( Figure ). [ncbi.nlm.nih.gov]

The majority of the 15 cases of Haff disease reported here clustered between the epidemiological week 48 and 51 of 2016 [26-30 Dec 2016], however, new cases continued to be reported up to epidemiological week 14 of 2017 [week ending 7 Apr 2017] (Figure [outbreakwatch.blogspot.com]

We present the investigation of an outbreak of Haff disease in Nanjing, Jiangsu Province, China incorporating both epidemiological and chemical analysis. [infona.pl]

Implicated drugs, pathophysiology and management". Drug Saf. 13 (2): 94–104. doi : 10.2165/00002018-199513020-00004. PMID 7576268. ^ Frank, Christopher (2008). "Recognition and treatment of serotonin syndrome". Can Fam Physician. 54 : 988–92. [en.wikipedia.org]

When Haff disease is suspected, proper treatment should be initiated as soon as possible to prevent deterioration in the condition of the patient. [ncbi.nlm.nih.gov]

Centers for Disease Control and Prevention (CDC). Haff disease associated with eating buffalo fish—United States, 1997. MMWR Morb Mortal Wkly Rep 1998;47(50):1091-1093.Google Scholar 5. Chan, TY. [cambridge.org]

Get the skills you need now with new information on global humanitarian relief and expedition medicine, plus expanded coverage of injury prevention and environmental preservation. [books.google.com]

Nanjing 210009, Jiangsu, PR China Guoxiang Xie Nanjing Municipal Center for Disease Control and Prevention, Nanjing 210003, Jiangsu, PR China Shiqi Zhen Institute of Food Safety and Assessment, Jiangsu Provincial Center for Disease Control and Prevention [infona.pl]

To stop spread of hepatitis A among MSM in Europe, a European consensus on prevention and control measures may be required. (R.A.) Auteur : Mazick A, Howitz M, Rex S, Jensen IP, Weis N, Katzenstein TL, Haff J, Molbak K Eurosurveillance. [santepubliquefrance.fr]