Presentation
Case 3 48-year-old male Presented with distressing visual experiences Variable severity Present for over 20 years Examples of visual effects Red objects have a green shimmer around them like with 3D glasses Altered sense of distance Alteration of his [thedrugclassroom.com]
If only three are present, the disorder is mild, five equates to moderate and six or above is classed as a severe disorder. [creativecareinc.com]
The criteria encourages clinicians to consider the whole disease course and see if mood episodes have been present for most of it. [everydayhealth.com]
Bazer took the medication in a treatment room, with therapists present for support. During the session, she said she saw her fear inside her body. “It was a hard mass black under my ribcage. [cbsnews.com]
Because sleep-related hallucinations are sometimes linked to other sleep disorders, a sleep specialist will evaluate a patient’s health history and sleep patterns to determine if another disorder is present. [tuck.com]
Entire Body System
- Crying
"I use to cry in the toilets, hopeless and broken," she tells me. [vice.com]
[…] starry, starry night, but black, deep space… very awe-inspiring, but very dark, impersonal… Then I started getting technicolor everything, then things on Earth, like this incredible crystal turquoise… Half the time I was laughing, half the time I was crying [pbs.org]
For all you know, it's a cry for attention, or something else for her to blame all her problems on. [drugs-forum.com]
Cardiovascular
- Palpitations
Two or more of the following signs develop: pupillary dilation, tachycardia, sweating, palpitations, blurring of vision, tremors, or incoordination. [mentalhealth.com]
Psychiatrical
- Visual Hallucination
Organic brain disorder, eg brain tumour, delirium, dementia, visual hallucination due to epileptic activity. Visual hallucinations due to another drug and/or associated medical condition, eg Parkinson's disease and L-dopa. Factitious illness. [patient.info]
Hallucinogen persisting perception disorder HPPD noise simulation, often referred to as visual snow Specialty Psychiatry Hallucinogen persisting perception disorder ( HPPD ) is a disorder in which a person has flashbacks of visual hallucinations or distortions [en.wikipedia.org]
Relatively small doses of the drug, usually 25 to 80 mcg, bring on sensory alterations and visual hallucinations. Some people experience sensory distortion, such as seeing sound or hearing colors. [lsdabusehelp.com]
During the trip, the user experiences vivid visual hallucinations, a slowing of the subjective sense of time, feelings of depersonalization, strong emotional reactions, and a disruption of logical thought. [sites.sinauer.com]
Complications Other Hallucinogen Use Disorder (especially with LSD) can cause visual hallucinations that are frightening. [mentalhealth.com]
- Withdrawn
On the other hand, those who “crash” from stimulants are tired, withdrawn, and depressed. Virtually any substance taken in very large quantities over a long enough period can lead to a psychotic state. [ncbi.nlm.nih.gov]
PCP was withdrawn from clinical use because of its prominent adverse side effects, but ketamine, which is less potent than PCP, has significant applications in both human and veterinary medicine. [sites.sinauer.com]
An article on About.com describes a phenomenon known as “amotivational syndrome” that happen to regular pot smokers: they become socially withdrawn and “perform at a level of everyday functioning well below their capacity prior to their marijuana use. [psychcentral.com]
Clonazepam continued for 5 weeks and then withdrawn. Even after clonazepam ended, continued improvement occurred. [thedrugclassroom.com]
- Auditory Hallucination
But these recreational users may not realize that the visual and auditory hallucinations, sensory disturbances and dissociative experiences associated with psychedelic drugs can return months or even years after using a drug. [blackbearrehab.com]
Hallucinogen hallucinations usually are more visual (e.g., enhanced colors and shapes) as compared to schizophrenic-type hallucinations, which tend to be more auditory (e.g., voices). [ncbi.nlm.nih.gov]
- Paranoid Ideation
Hallocinogen Intoxication causes significant psychological and social impairment (e.g., marked anxiety or depression, ideas of reference, fear of losing one's mind, paranoid ideation, impaired judgment, or impaired social or occupational functioning). [mentalhealth.com]
- Dysphoric Mood
Case 5 18-year-old male Hospitalized for perceptual impairment and dysphoric mood that was present for 8 months. Family history of psychiatric problems Had regularly used cannabis, at least some each week. [thedrugclassroom.com]
Urogenital
- Dyspareunia
[…] of Infancy, Childhood, or Adolescence NOS 315.2 Disorder of Written Expression 312.9 Disruptive Behavior Disorder NOS 300.12 Dissociative Amnesia 300.15 Dissociative Disorder NOS 300.13 Dissociative Fugue 300.14 Dissociative Identity Disorder 302.76 Dyspareunia [dr-bob.org]
[Indicate the General Medical Condition ] 608.89 Male Dyspareunia Due to...[Indicate the General Medical Condition 608.89 Male Hypoactive Sexual Desire Disorder Due to... [behavenet.com]
Neurologic
- Agitation
Withdrawal results in agitation, severe body aches, gastrointestinal symptoms, dysphoria, and craving to use more opioids. [ncbi.nlm.nih.gov]
An immediate sense of well being and relaxation Euphoria An increase in the breathing rate Blurred vision Impaired coordination Hallucinations Distorted senses of perception Disorganized thought process Anxiety and agitation Feelings of panic Numbness [disorders.org]
Such extremes, known as behavior toxicity, may lead to a level of heightened agitation brought on by hallucinations. People in this state may commit suicide or end up dying in an accident. [lsdabusehelp.com]
People can experience any combination of the following symptoms, such as: Changes in weight (usually weight gain) Fatigue An inability to concentrate or focus Irritability Agitation Joylessness Hopelessness Isolation from friends and family members Changes [sobercollege.com]
"I get easily agitated." "I can be stirred up easily.". * Anxiety: " I worry about almost everything ." "I'm always fearful or on edge about bad things that might happen." "I always expect the worst to happen." "I am a very anxious person." [mentalhealth.com]
- Excitement
“I do think it’s very exciting and we should be looking scientifically at how this can help patients. If we get one more patient better, then that’s fantastic.” [time.com]
It is either the most exciting new treatment for depression in years or it is a hallucinogenic club drug that is wrongly being dispensed to desperate patients in a growing number of clinics around the country. [nytimes.com]
"People had been very excited about LSD, in part because it looks a lot like the serotonin molecule, which regulates mood." Indeed, at the time, LSD was the most researched psychiatric drug in the world, with over a thousand studies conducted on it. [vice.com]
Thus, it seems there are different pathways reducing the symptoms of visual disturbances, so HPPD may arise from either excitation or inhibition of visual networks [ 43 - 49 ]. [omicsonline.org]
- Sensory Distortion
Lysergic acid diethylamide (LSD) is a hallucinogenic drug which when taken produces powerful sensory distortions, intensifies mood and alters thought processes. [sl.nsw.gov.au]
Relatively small doses of the drug, usually 25 to 80 mcg, bring on sensory alterations and visual hallucinations. Some people experience sensory distortion, such as seeing sound or hearing colors. [lsdabusehelp.com]
The acute effects of PCP and ketamine include sensory distortions and altered body image, cognitive disorganization, and various affective changes. [sites.sinauer.com]
- Macropsia
Here’s an example: Case 1 26-year-old male Five year history of cannabis use Also reported LSD use During which there was macropsia, micropsia, pelopsia, and teleopsia. [thedrugclassroom.com]
Macropsia and micropsia (objects appear respectively larger or smaller than normal). [patient.info]
No micropsia or macropsia was reported. The symptoms were aggravated by mental stress, lack of sleep and after drinking caffeine containing beverages. These visuals disturbances severely impaired the patient’s reading capacity. [omicsonline.org]
- Micropsia
HPPD appeared after using cannabis Vivid & saturated color, macro/micropsia, and seeing things in motion as moving faster than reality. [thedrugclassroom.com]
Macropsia and micropsia (objects appear respectively larger or smaller than normal). [patient.info]
No micropsia or macropsia was reported. The symptoms were aggravated by mental stress, lack of sleep and after drinking caffeine containing beverages. These visuals disturbances severely impaired the patient’s reading capacity. [omicsonline.org]
Treatment
[…] advice for patient management, summarising treatment specifics with tables and treatment flowcharts). [books.google.com]
Fewer facilities offer integrated treatment programs, so it’s important to find out the available treatments before seeking treatment. [lsdabusehelp.com]
Feifel is one of a few academic psychiatrists to offer ketamine treatment. [nytimes.com]
Bottom line: Hallucinogenic drugs are attracting renewed attention as potential treatments for psychological disorders — particularly in people who have not responded to conventional treatments. [psychcentral.com]
Prognosis
Prognosis [ 7 ] Symptoms should settle over a period of months and do seem to respond to pharmacotherapy in the majority of cases. However, some patients may experience distressing symptoms that last for years or are irreversible. [patient.info]
Prognosis Because hallucinogens are not physically addictive, many people are able to stop using these drugs successfully. [minddisorders.com]
Etiology
It echoes the progress in psychiatry regarding the establishment of an evidenced-based model of taxonomy, diagnosis, etiology, and treatment. [books.google.com]
Current knowledge with regard to risk factors, etiology and therapeutic options is thus limited and must be interpreted with caution [ 3, 8 ]. [omicsonline.org]
There is evidence from the history, physical examination, or laboratory findings that the symptoms developed during or within a month after substance intoxication or withdrawal, or medication use, is etiologically related to the mood disturbance. 3. [ncbi.nlm.nih.gov]
Therapy: randomized controlled trial Drug Therapy: multicenter randomized controlled trial Drug Therapy: placebo-controlled randomized controlled trial Economic Impact Education Electroconvulsive Therapy Embryology Enzymology Epidemiology Escitalopram Etiology [mentalhealth.com]
Epidemiology
Education and Training 349 349 Lifespan Developmental Psychology 3 5 MöLLER H J Prof Dr LudwigMaximiliansUniversität München 7 Developmental Psychopathology 13 13 Child and Adolescent Psychiatry and Psychotherapy 29 Diagnosis and Classification 37 36 Epidemiology [books.google.com]
Epidemiology of hallucinogen use in the U.S. results from the National epidemiologic survey on alcohol and related conditions III. Addictive Behaviors, Vol. 89, Issue., p. 35. [bjp.rcpsych.org]
Epidemiology It is exceedingly uncommon on a population basis and probably still extremely rare in the population that has taken hallucinogenic drugs. No reliable prevalence data are available. [patient.info]
International Consortium in Psychiatric Epidemiology (2005) Appendix for “New Scales to Screen for Serious Mental Illness in the General Population”. Available: http://www.hcp.med.harvard.edu/icpe/smi_appendix.php. Accessed 2013 Apr 30. 26. [journals.plos.org]
Doxepin Drug Therapy Drug Therapy: randomized controlled trial Drug Therapy: multicenter randomized controlled trial Drug Therapy: placebo-controlled randomized controlled trial Economic Impact Education Electroconvulsive Therapy Embryology Enzymology Epidemiology [mentalhealth.com]
Pathophysiology
Despite 60 years of research into HPPD, a unifying pathophysiological model has yet to emerge. [omicsonline.org]
Prevention
Psychiatric Classification 31 31 Empirical Research Relating to ICD10 42 42 ICD10 and DSMIV 51 51 Examination of the Psychiatric Patient 95 95 Standardised Measurement Instruments in Psychiatry 113 113 Assessing the Quality of Life in Mental Illness 135 134 Prevention [books.google.com]
Prevention Hallucinogen use is difficult to prevent, because these drugs have a reputation for being non-addictive and "harmless." [minddisorders.com]
To prevent the greenhouse effect at homes, one should draw the blinds and shades in the house. Staying in the AC is another way of protecting oneself from the nagging summer heat and escaping the tendency to feel depressed. [sovhealth.com]
Prevention [ 7 ] Avoidance of hallucinogenic and other recreational drugs associated with the condition. Failing that, avoidance of excessive or frequently repeated use of these drugs. [patient.info]
To download the ICD-10-CM, visit the Centers for Disease Control and Prevention website and go to "FY 2016 release of ICD-10-CM" section. Select ICD-10-CM PDF format to access a PDF version of the document. [apapracticecentral.org]