(hallux varus), a useful diagnostic sign when present Small great toenail Fifth-finger clinodactyly, secondary to a shortened middle phalanx Short feet Altered dermatoglyphics of the hands; when present, primarily involving distal placement of the axial [en.wikipedia.org]

Considering the molecular data, the phenotype in the present patient was defined as the severe end of hand-foot-genital and Guttmacher syndrome spectrum. [ncbi.nlm.nih.gov]

2438 Synonym(s): HFGS Hand-foot-uterus syndrome Prevalence: - Inheritance: Autosomal dominant Age of onset: Antenatal, Neonatal ICD-10: Q51.2 OMIM: 140000 UMLS: C1841679 MeSH: - GARD: 2594 MedDRA: 10072361 The documents contained in this web site are presented [orpha.net]

[…] convalescent antibody levels) may be obtained Differentiating coxsackievirus-associated HFMD from EV-71–associated HFMD may have prognostic significance PCR and microarray technology are among the various ways of identifying the causative virus [3] See Workup [emedicine.medscape.com]

The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment. [orpha.net]

Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. [books.google.com]

Treatment - Hand foot uterus syndrome There is no specific therapy that removes, cures, or repairs all effects of hand-foot-uterus syndrome. Management of HFU mainly involves the treatment of specific effects. [checkorphan.org]

Prognosis - Hand foot uterus syndrome Since HFU results in a variety of physical signs and symptoms, the prognosis for each affected individual varies. Most people with mild or moderate hand, genital, or foot abnormalities lead normal lives. [checkorphan.org]

What is the prognosis of hand, foot, and mouth disease? The prognosis for routine HFMD is excellent. A patient's symptoms are bothersome but not debilitating. [medicinenet.com]

Prognosis [ 1 ] This is generally excellent with a full recovery in the vast majority people. Symptoms tend to improve within 3-6 days, usually with full resolution of skin and mouth lesions within 7-10 days. [patient.info]

[…] extremeties (feet or hand) enchondroma benign feet/hand elevation of the periostiom of metaphysis of long bones near the knee in someone with Paget's, bone infarcts, radiation or familial retinoblastoma osteosarcoma (osteogenic sarcoma) malignant - poor prognosis [quizlet.com]

[…] interstitial and granulonodulo alveolar pattern 324 Interstitialreticular pulmonary pattern 326 Disseminated interstitial pneumonitis 327 The miliary pattern of pneumonia 328 Short linear andor wedgeshaped densities 329 Pulmonary edema in infancy and childhood Etiology [books.google.com]

Most cases affect children younger than 10 years old. 3 Etiology and Pathophysiology HFMD is most commonly caused by members of the enterovirus genus, especially coxsackie viruses. [mhmedical.com]

Management There is no antiviral agent specific for the etiologic agents of HFMD. [emedicine.medscape.com]

Molecular epidemiology of enterovirus 71 infection in the Western Pacific Region. Pediatr Int. 2004 Apr. 46(2):231-5. [Medline]. Singh S, Poh CL, Chow VT. [emedicine.medscape.com]

Epidemiology [ 1, 2 ] HFMD occurs worldwide, with a peak incidence in the summer and autumn in temperate climates. It is most common among infants and children aged younger than 10 years but can occur at any age. [patient.info]

Most cases affect children younger than 10 years old. 3 Etiology and Pathophysiology HFMD is most commonly caused by members of the enterovirus genus, especially coxsackie viruses. [mhmedical.com]

Pathophysiology Infection generally occurs via the fecal-oral route or via contact with skin lesions and oral secretions. Viremia develops, followed by invasion of the skin and mucous membranes. [emedicine.medscape.com]

The alanine tract elongation may prevent protein-protein interactions of the mutant HOXA13, thereby inducing a localized heterochrony in the sequence of distal limb and genitourinary development. [ncbi.nlm.nih.gov]

[…] disease, renal disease) # Nonuterine bleeding –Vaginal (tear, trauma, or cancer) –Cervical (trauma or cancer) –Urinary (UTI or cancer) –Rectal (bleeding, trauma, fissure, or cancer) # Other malignancy (ovarian or uterine tumor, sarcoma) # Endometrioma Prevention [checkorphan.org]

Many of the suggested prevention strategies or treatments for HFS are based on this theory. How can I prevent HFS? Unfortunately, there is nothing that is guaranteed to prevent HFS. [oncolink.org]

Prevention of HFMD Good personal hygiene is essential to prevent the spread of HFMD to others, both for those infected and their carers. [betterhealth.vic.gov.au]

Treatment and Prevention There is no known therapy or preventive measures that doctors know of at the present time. [feetfirstinc.com]