(hallux varus), a useful diagnostic sign when present Small great toenail Fifth-finger clinodactyly, secondary to a shortened middle phalanx Short feet Altered dermatoglyphics of the hands; when present, primarily involving distal placement of the axial[en.wikipedia.org]
A grade IV hypospadias, which was the most severe genital anomaly in affected males, was present in the youngest, moderately mentally retarded microcephalic male sibling.[ncbi.nlm.nih.gov]
We report the case of a 13-year-old female with Hand-Foot-Genital syndrome presenting to our foot and ankle clinic with tarsal coalition and hallux valgus interphalangeus - an unusual variation on the previously reported hallux varus associated with the[ncbi.nlm.nih.gov]
2438 Synonym(s): HFGS Hand-foot-uterus syndrome Prevalence: - Inheritance: Autosomal dominant Age of onset: Antenatal, Neonatal ICD-10: Q51.2 OMIM: 140000 UMLS: C1841679 MeSH: - GARD: 2594 MedDRA: 10072361 The documents contained in this web site are presented[orpha.net]
Considering the molecular data, the phenotype in the present patient was defined as the severe end of hand-foot-genital and Guttmacher syndrome spectrum.[ncbi.nlm.nih.gov]
We report on a girl with absentnails, short/absent distal phalanges of the second to fifth fingers and toes, short thumbs, absent halluces, and carpo-tarsal coalition who also had genitourinary malformations.[ncbi.nlm.nih.gov]
The proband had features of HFGS that included bilateral vesicoureteric junction obstruction with ectopic ureters, brachydactyly of various fingers and toes, hypoplastic thenar eminences, and absentnails on both 4th toes and right 5th toe.[ncbi.nlm.nih.gov]
ejaculation (related to structural anomalies and weakness of the bladder sphincter muscle)[en.wikipedia.org]
ejaculation (related to structural anomalies and weakness of the bladder sphincter muscle) References a b Innis, Jeffrey W; Pagon, RA; Bird, TD; Dolan, CR; Stephens, K (2006).[howlingpixel.com]
[…] progestin or oral contraceptive use o Anatomic or structural lesions –Uterine leiomyoma (fibroids) –Foreign body (often intrauterine device) –Cervical or uterine polyps o Pelvic infection (cervicitis, pelvic inflammatory disease) o Hypothalamic lesion o Hyperprolactinemia[checkorphan.org]
The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net]
Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography.[books.google.com]
Rapidly consult with trusted authorities thanks to new expert-opinion treatment strategies and recommendations. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography.[books.google.com]
Treatment - Hand foot uterus syndrome There is no specific therapy that removes, cures, or repairs all effects of hand-foot-uterus syndrome. Management of HFU mainly involves the treatment of specific effects.[checkorphan.org]
It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice .[uniprot.org]
Prognosis - Hand foot uterus syndrome Since HFU results in a variety of physical signs and symptoms, the prognosis for each affected individual varies. Most people with mild or moderate hand, genital, or foot abnormalities lead normal lives.[checkorphan.org]
Prognosis [ 1 ] This is generally excellent with a full recovery in the vast majority people. Symptoms tend to improve within 3-6 days, usually with full resolution of skin and mouth lesions within 7-10 days.[patient.info]
[…] extremeties (feet or hand) enchondroma benign feet/hand elevation of the periostiom of metaphysis of long bones near the knee in someone with Paget's, bone infarcts, radiation or familial retinoblastoma osteosarcoma (osteogenic sarcoma) malignant - poor prognosis[quizlet.com]
Most cases affect children younger than 10 years old. 3 Etiology and Pathophysiology HFMD is most commonly caused by members of the enterovirus genus, especially coxsackie viruses.[mhmedical.com]
Epidemiology [ 1, 2 ] HFMD occurs worldwide, with a peak incidence in the summer and autumn in temperate climates. It is most common among infants and children aged younger than 10 years but can occur at any age.[patient.info]
Most cases affect children younger than 10 years old. 3 Etiology and Pathophysiology HFMD is most commonly caused by members of the enterovirus genus, especially coxsackie viruses.[mhmedical.com]
The alanine tract elongation may prevent protein-protein interactions of the mutant HOXA13, thereby inducing a localized heterochrony in the sequence of distal limb and genitourinary development.[ncbi.nlm.nih.gov]
[…] disease, renal disease) # Nonuterine bleeding –Vaginal (tear, trauma, or cancer) –Cervical (trauma or cancer) –Urinary (UTI or cancer) –Rectal (bleeding, trauma, fissure, or cancer) # Other malignancy (ovarian or uterine tumor, sarcoma) # Endometrioma Prevention[checkorphan.org]
Many of the suggested prevention strategies or treatments for HFS are based on this theory. How can I prevent HFS? Unfortunately, there is nothing that is guaranteed to prevent HFS.[oncolink.org]
Prevention of HFMD Good personal hygiene is essential to prevent the spread of HFMD to others, both for those infected and their carers.[betterhealth.vic.gov.au]
Treatment and Prevention There is no known therapy or preventive measures that doctors know of at the present time.[feetfirstinc.com]