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Heart Transplantation

Cardiac Transplantation


Presentation

  • When it occurs, presentation is usually obvious, and it carries high morbidity unless emergent and timely surgical treatment is instituted.[ncbi.nlm.nih.gov]
Internal Bleeding
  • This crypto-symptomatic pancreatitis was not diagnosed until massive internal bleeding and hemorrhagic shock occurred, because the typical presentations of acute pancreatitis were masked by the intra-abdominal manifestations caused by right heart failure[ncbi.nlm.nih.gov]
Heart Disease
  • BACKGROUND: Because survival on the heart transplantation waitlist depends on underlying heart disease, a new allocation system will include the type of heart disease.[ncbi.nlm.nih.gov]

Workup

  • […] fraction of less than 20% Intractable angina or malignant cardiac arrhythmias for which conventional therapy has been exhausted Pulmonary vascular resistance of less than 2 Wood units Age younger than 65 years Ability to comply with medical follow-up care Workup[emedicine.medscape.com]
White Matter Lesions
  • Brain magnetic resonance image revealed a new white matter lesion in the splenium. On immunohistochemistry, there was SV40-positive staining in gastric and heart biopsy specimens.[ncbi.nlm.nih.gov]

Treatment

  • Surgical repair is usually the only definitive treatment for these patients because medical management is associated with a 30-day mortality approaching 100%.[ncbi.nlm.nih.gov]

Prognosis

  • The prognosis of amyloid heart disease is poor with 1-year survival rates of 35 to 40%.[ncbi.nlm.nih.gov]

Etiology

  • The etiology and management of this complication are reviewed.[ncbi.nlm.nih.gov]
  • Training in clinical management of heart failure includes supervised experience in both inpatient and outpatient settings and involves a spectrum of underlying etiologies for the heart failure.[heart.ucla.edu]
  • Possible etiologies including sympathetic denervation, ischemic injury to the sinus node, and graft ischemia.[openanesthesia.org]
  • Implicated as well is that female heart failure patients may be up to 3 times more likely to refuse heart transplantation than men. 14 Finally, some series have suggested that when compared with men, women with advanced heart failure of nonischemic etiologies[doi.org]
  • We aim to review the epidemiology of coronary artery disease in this population and the etiology as it relates to ESRD and its associated co-factors.[academic.oup.com]

Epidemiology

  • We sought to determine the impact of valganciclovir (VGC) duration on the epidemiology of CMV infections after heart transplantation.[ncbi.nlm.nih.gov]
  • In this chapter, we will review the epidemiology, natural history, clinical manifestations, screening and diagnostic strategies for CAV while emphasizing current treatment strategies designed to prevent or slow the progression of this disease. 2.[intechopen.com]
  • Diagnosis N/A Pathophysiology N/A Epidemiology N/A Special considerations for nursing and allied health professionals. N/A What's the evidence? Rose, EA. "Long-term use of a left ventricular assist device for end-stage heart failure".[clinicaladvisor.com]
  • PCS are such lethal diseases with a median overall survival of only 6 months in patients with diagnoses of PCS registered in the Surveillance, Epidemiology and End Results database [ 1 ].[cardiothoracicsurgery.biomedcentral.com]
  • We aim to review the epidemiology of coronary artery disease in this population and the etiology as it relates to ESRD and its associated co-factors.[academic.oup.com]
Sex distribution
Age distribution

Pathophysiology

  • Software-assisted EMB analysis may enable greater pathophysiologic understanding of LGD and identification of targets for future study and intervention. Copyright 2017 International Society for the Heart and Lung Transplantation.[ncbi.nlm.nih.gov]
  • Evidence suggests that aerobic exercise training may be effective in reversing the pathophysiological consequences associated with cardiac denervation and prevent immunosuppression-induced adverse effects in heart transplant recipients.[cochrane.org]
  • The pathophysiology of the transplanted heart is unique. The denervation of the organ makes it dependent on its intrinsic rate. As a result of the lack of neuronal input, some left ventricular hypertrophy results.[emedicine.medscape.com]

Prevention

  • Airway clearance with inhaled tPA or bronchoscopy may prevent the need for prolonged mechanical ventilation and reduce post-operative morbidity in this unique population.[ncbi.nlm.nih.gov]

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