Presentation
When it occurs, presentation is usually obvious, and it carries high morbidity unless emergent and timely surgical treatment is instituted. [ncbi.nlm.nih.gov]
Entire Body System
- Fatigue
The DuraHeart manufacturer's analysis revealed much damage to the insulation and fatigue fractures of the conductors, which had resulted in temporary cessation of function and failure of the magnetic levitation system. [ncbi.nlm.nih.gov]
ARB side effects may include: diarrhea, dizziness, headache, or fatigue. If you are taking either of these medications, your doctor may need to monitor your blood pressure, kidney function, and potassium levels regularly. [mountsinai.org]
Patients with worsening heart failure experience symptoms—such as difficulty breathing, fatigue or swelling—that increase in frequency or severity. [heartfailure.nm.org]
Patients can have no symptoms or symptoms of heart failure (shortness of breath, fatigue, fluid retention, decreased activity tolerance). Treatments may include changes to immunosuppressant medications and/or stent placement if necessary. [sharecare.com]
The angst and fatigue really transcend the image, and the more you look at it, the more you see – everything adds a new dimension. The surgeon sleeping in the corner, the bloody mess, the myriad of cables… I just don’t get tired of looking at it. [zmescience.com]
- Fever
An initially event-free period was followed by recurrent fever attacks and staphylococcal bacteremia was diagnosed. [ncbi.nlm.nih.gov]
At home, patients watch for other signs of rejection, including shortness of breath, flu-like symptoms, and low-grade fever. [montefiore.org]
Continued Warning signs of infection include: Fever over 100.4°F (38°C) Sweats or chills Skin rash Pain, tenderness, redness, or swelling Wound or cut that won't heal Red, warm, or draining sore Sore throat, scratchy throat, or pain when swallowing Sinus [webmd.com]
- Falling
Applications are reviewed in early fall, and prospective fellows are notified in late fall regarding status for interview. Interviews are by invitation only. [medicine.iupui.edu]
And finally, the film will shows how history can be rewritten when a system seemingly cemented in place for eternity, falls apart. [imdb.com]
Donors after cardiac death can fall into the SCD or ECD category, depending upon the donor's age, cause of death and creatinine levels. [health.ucdavis.edu]
We have previously reported on the significant limitations in applying this risk stratification in our population (developing country) where the majority will fall into the high risk Class III group and further there is significant heterogeneity within [bloodjournal.org]
- Weight Gain
Analyzed risk factors were: non-immunologic recipient risk factors (age of transplantation, smoking, hypertension, lipids, diabetes, obesity and weight gain after HT), immunologic recipient risk factors (acute cellular rejection (ACR), acute humoral rejection [ncbi.nlm.nih.gov]
Consult your doctor if you have decreased blood pressure, feel dizzy or faint, experience weight gain, have a persistent cough, have swelling of the face, or if you become pregnant. [mountsinai.org]
Also, watch your child for signs of infection or rejection, including: fever tiredness trouble breathing vomiting weight gain poor appetite Call your doctor right away if these or any other problems happen. [kidshealth.org]
gain and kidney problems Many of these problems are treatable, although sometimes another heart transplant may need to be carried out if possible. [nhs.uk]
- Chills
Continued Warning signs of infection include: Fever over 100.4°F (38°C) Sweats or chills Skin rash Pain, tenderness, redness, or swelling Wound or cut that won't heal Red, warm, or draining sore Sore throat, scratchy throat, or pain when swallowing Sinus [webmd.com]
These include: weakness, fatigue, malaise (feeling lousy), fever, and " flu -like symptoms", such as chills, headaches, dizziness, diarrhea, nausea and/or vomiting. [medicinenet.com]
Respiratoric
- Cough
A 13-year-old girl had been diagnosed with dilated cardiomyopathy 5 years before this case, due to intractable dyspnoea and cough. She received multiple medical treatments after diagnosis, with minimal effects. [ncbi.nlm.nih.gov]
ACE-I side effects may include dizziness, non-productive cough, or in rare occasions swelling of your face, lips, or throat. [mountsinai.org]
When you are able to breathe completely on your own and are able to cough, your doctor will remove the breathing tube. After the breathing tube is out, a nurse will help you cough and take deep breaths every 2 hours. [hopkinsmedicine.org]
Cardiovascular
- Heart Disease
BACKGROUND: Because survival on the heart transplantation waitlist depends on underlying heart disease, a new allocation system will include the type of heart disease. [ncbi.nlm.nih.gov]
Electrophysiology Hypertension Clinic Interventional and Structural Heart Disease Marfan Syndrome Clinic Nuclear Cardiology The Advanced Heart Failure and Cardiac Transplant Team has one of the most active advanced heart failure programs in the region [cardiology.wustl.edu]
Read more In addition, our results exceed national standards for heart transplantation for people with irreversible, life-threatening heart disease. [health.ucsd.edu]
By numbers, the ischaemic heart disease on the basis of a coronary heart disease is the most significant one. Then follow dilative cardiomyopathy and valvular diseases. [klinikum.uni-heidelberg.de]
- Vascular Disease
BACKGROUND: The hemodynamic definitions of pulmonary hypertension (PH) in left heart disease have recently been refined to better match the characteristics required to reflect the presence of pulmonary vascular disease. [ncbi.nlm.nih.gov]
Poor glucose control and onset of disease under the age of 20 years are often associated with progressive target-organ dysfunction (particularly renal failure) and coronary, cerebral, and peripheral vascular disease, with MI, stroke, claudication/amputations [ahajournals.org]
Learn more » Vascular Surgery Offering comprehensive care of vascular disease through preventive services, diagnostic expertise, minimally invasive therapies and traditional surgical techniques. [cts.usc.edu]
(myocarditis, infiltrative disease, etc.) [mcw.edu]
A constant 4% decrease occurs yearly after the first year as the incidence of coronary allograft vascular disease increases. [surgeryencyclopedia.com]
- Chest Pain
A 47-year-old active duty male initially evaluated for atypical chest pain was found to have severe concentric left ventricular hypertrophy on echocardiogram but normal voltage on electrocardiogram. [ncbi.nlm.nih.gov]
Patient Care Centers of Excellence Adult Congenital Heart Disease Advanced Heart Failure and Cardiac Transplantation Cardiac Intensive Care Unit Cardiology Consultants Cardiovascular Genetics Cardio-Oncology Cardiovascular Imaging Chronic Chest Pain Clinic [cardiology.wustl.edu]
You will not be able to receive sensations from your heart such as angina (chest pain). Studies are showing that in some cases nerve paths begin to re-grow, and people have reported feeling chest pain. Call 911 if you feel chest pain. [allinahealth.org]
Take the test Heart attacks aren't always what you think Symptoms aren't always sudden or severe, and some people don't experience chest pain at all. [heartfoundation.org.au]
News & World Report American Heart Association and American College of Cardiology’s Platinum Performance Award for Heart Attack Care Accredited as a Chest Pain Center by the Society of Cardiovascular Patient Care Lifeline Gold Quality Achievement Award [sutterhealth.org]
- Hypotension
We present a case of a 61-year-old man with ischemic cardiomyopathy receiving sacubitril/valsartan (Entresto; Novartis, Cambridge, MA) who developed profound hypotension after HT. [ncbi.nlm.nih.gov]
Transplanted hearts have no baseline parasympathetic innervation and thus don’t have the normal tachycardia and increased contractility response to hypotension/hypovolemia. Reflex venous contriction response to hypotension still exists. [openanesthesia.org]
These included: fixed pulmonary hypertension, reactive pulmonary hypertension with systemic hypotension, reactive pulmonary hypertension without systemic hypotension, and normal pulmonary artery pressure/PVR. [thecardiologyadvisor.com]
However, if on referral the patient is in cardiogenic shock or on parenteral inotropic agents and cannot be tapered because of hypotension, end-organ dysfunction, or symptoms, then the options for this patient are limited to cardiac transplantation, mechanical [circ.ahajournals.org]
Neurologic
- Stroke
Olympic sprinter shares his stroke story Learn the warning signs of stroke No bones about it: It’s time to fight heart disease with Best Friend Fridays The American Heart Association’s new effort looks to put pets in the workplace, while helping raise [americanheart.org]
Google Scholar 3 American Heart Association Heart and Stroke Facts. http://www.americanheart.org/statistics. Google Scholar 4 Miller LW. [ahajournals.org]
There was, however, a striking difference in the rates of stroke. [doi.org]
Use our Heart Age Calculator to find out your heart age compared to your actual age and if you are at risk of a heart attack or stroke. [heartfoundation.org.au]
Adams R (2013) Toward a Stroke-Free Childhood in Sickle Cell Disease, Stroke, 44 :10, (2930-2934), Online publication date: 1-Oct-2013. [circ.ahajournals.org]
- Seizure
She was sent home on a short course of seizure prophylaxis, which was discontinued after the resolution of radiological findings. She had no further episodes of seizures for 6 months following discontinuation of her anti-epileptic regimen. [ncbi.nlm.nih.gov]
Other acute and chronic illness: Active peptic ulcer disease, gastrointestinal bleeding, and recent stroke or seizure are all examples of relative acute contraindications to transplant. [thecardiologyadvisor.com]
Workup
[…] fraction of less than 20% Intractable angina or malignant cardiac arrhythmias for which conventional therapy has been exhausted Pulmonary vascular resistance of less than 2 Wood units Age younger than 65 years Ability to comply with medical follow-up care Workup [emedicine.medscape.com]
Serum
- Hypercholesterolemia
RESULTS: T. gondii seropositive recipients were older, had higher body mass index, and presented higher prevalence of hypertension, hypercholesterolemia, COPD and Cytomegalovirus seropositivity than T. gondii seronegative recipients. [ncbi.nlm.nih.gov]
Hyperlipidemia Hypercholesterolemia and hypertriglyceridemia have prevalence rates of 40 and 60%, respectively, among RTR ( 43 ). [cjasn.asnjournals.org]
[…] of mTOR inhibitors include hypertension, headaches, acne, impaired wound healing, oral ulceration, anemia, thrombocytopenia, thrombotic microangiopathy, venous thromboses, lymphedema, pulmonary toxicity, alveolar hemorrhage, hypertriglyceridemia and hypercholesterolemia [thecardiologyadvisor.com]
The most commonly reported side effects of MMF include leukopenia, anemia, infections, systemic cytomegalovirus disease, hypercholesterolemia and gastrointestinal complications such as diarrhea, nausea and dyspepsia. [intechopen.com]
Treatment
Many work groups observed an increased portion of patients with heart arrhythmias who partly required permanent pacemaker treatment. [klinikum.uni-heidelberg.de]
Surgical repair is usually the only definitive treatment for these patients because medical management is associated with a 30-day mortality approaching 100%. [ncbi.nlm.nih.gov]
Prognosis
The prognosis of amyloid heart disease is poor with 1-year survival rates of 35 to 40%. [ncbi.nlm.nih.gov]
News & Views Prognosis after heart... [bmj.com]
Etiology
The etiology and management of this complication are reviewed. [ncbi.nlm.nih.gov]
Possible etiologies including sympathetic denervation, ischemic injury to the sinus node, and graft ischemia. [openanesthesia.org]
Training in clinical management of heart failure includes supervised experience in both inpatient and outpatient settings and involves a spectrum of underlying etiologies for the heart failure. [heart.ucla.edu]
We aim to review the epidemiology of coronary artery disease in this population and the etiology as it relates to ESRD and its associated co-factors. [academic.oup.com]
Implicated as well is that female heart failure patients may be up to 3 times more likely to refuse heart transplantation than men. 14 Finally, some series have suggested that when compared with men, women with advanced heart failure of nonischemic etiologies [doi.org]
Epidemiology
We sought to determine the impact of valganciclovir (VGC) duration on the epidemiology of CMV infections after heart transplantation. [ncbi.nlm.nih.gov]
In this chapter, we will review the epidemiology, natural history, clinical manifestations, screening and diagnostic strategies for CAV while emphasizing current treatment strategies designed to prevent or slow the progression of this disease. 2. [intechopen.com]
Diagnosis N/A Pathophysiology N/A Epidemiology N/A Special considerations for nursing and allied health professionals. N/A What's the evidence? Rose, EA. "Long-term use of a left ventricular assist device for end-stage heart failure". [clinicaladvisor.com]
PCS are such lethal diseases with a median overall survival of only 6 months in patients with diagnoses of PCS registered in the Surveillance, Epidemiology and End Results database [ 1 ]. [cardiothoracicsurgery.biomedcentral.com]
We aim to review the epidemiology of coronary artery disease in this population and the etiology as it relates to ESRD and its associated co-factors. [academic.oup.com]
Pathophysiology
Software-assisted EMB analysis may enable greater pathophysiologic understanding of LGD and identification of targets for future study and intervention. Copyright © 2017 International Society for the Heart and Lung Transplantation. [ncbi.nlm.nih.gov]
The primary goal of this fellowship is to provide a thorough knowledge of the diagnosis and treatment of congestive heart failure with an emphasis on pathophysiology, therapeutics, and prevention as well as on the humanistic, moral, and ethical aspects [heart.ucla.edu]
Evidence suggests that aerobic exercise training may be effective in reversing the pathophysiological consequences associated with cardiac denervation and prevent immunosuppression-induced adverse effects in heart transplant recipients. [cochrane.org]
Prevention
Ultra-fast anesthesia might provide the most effective measure to prevent this type of complication. Immediate extubation after heart transplantation (IEAHT) has recently been reported in adult patients. [ncbi.nlm.nih.gov]
The third stage of heart transplant is the postoperative period, which is directed toward providing adequate antirejection treatment with close monitoring to prevent rejection of the heart. [britannica.com]