The present study highlighted the technical feasibility to produce polymeric bioresorbable functional heart valves by means of electrospinning. [ncbi.nlm.nih.gov]

• Fever

  The diagnosis of PVE was confirmed by the presence of continuous fever, transesophageal echocardiography and growth of penicillin-resistant Staphylococcus epidermidis from the valve prosthesis. [ncbi.nlm.nih.gov]

  Rheumatic Fever Rheumatic fever is usually caused by an untreated bacterial infection. Complications may not appear until much later in life. [verywell.com]

  Rheumatic fever - rarely seen now in western industrial nations Changes to the valvular apparatus due to infection, immunological, ischaemic, traumatic or degenerative factors Acquired valvular stenosis may be a consequence of organic changes to the tissue [coaguchek.com]

  Call your doctor if you have any of these signs of an infection: Fever over 100°F(38.4°C) Sweats or chills, particularly night sweats Skin rash Pain, tenderness, redness or swelling Wound or cut that won't heal Red, warm or draining sore Sore throat, [my.clevelandclinic.org]

• Dyspnea

  In patients with dyspnea, the New York Heart Association functional classification was 2.7 +/- 0.8 preoperatively versus 1.3 +/- 0.6 postoperatively. In patients with angina, it was 2.6 +/- 0.6 preoperatively versus 1.03 +/- 0.2 postoperatively. [ncbi.nlm.nih.gov]

  In one patient who had an aortic valve replacement 10 years ago and suffered from dyspnea for 2 months, one leaflet of the previously implanted bileaflet prosthesis was found to be missing during reoperation. [jtd.amegroups.com]

  Presentations may include the following: Acute prosthetic valve failure: Sudden onset of dyspnea, syncope, or precordial pain Acute aortic valve failure: Sudden death; survivors have acute severe dyspnea, sometimes accompanied by precordial pain, or syncope [emedicine.medscape.com]

  Patients were referred to AVR, if they suffered from isolated severe AS (peak velocity ≥4 m/s and mean pressure gradient ≥40 mmHg in the presence of normal left ventricular function, calculated valve area 2 ) and presented with symptoms (exertional dyspnea [journals.plos.org]

  Diagnosis Valve thrombosis should be suspected in any patient with any type of prosthetic valve who presents with a recent increase in dyspnea or fatigue because valve thrombosis can develop gradually and insidiously over several days or weeks. 9 Suspicion [circ.ahajournals.org]

• Exertional Dyspnea

  dyspnea ≥ functional NYHA class II and/or exertional angina pectoris ≥ functional CCS class II and/or syncope) or with reduced left ventricular function (ejection fraction ≤50%) when asymptomatic. [journals.plos.org]

• Regurgitation

  In the case of pathological regurgitation, it is also important to localize the origin of the regurgitant jet(s) to distinguish paravalvular from transvalvular regurgitation. [circ.ahajournals.org]

  On echocardiography, the aortic valve area was increased from 0.5 +/- 0.1 cm(2) to 1.70 +/- 0.03 cm(2) and the aortic regurgitation was paravalvular. [ncbi.nlm.nih.gov]

  Sometimes it causes regurgitation. Stenosis - when the valve doesn't open enough and blocks blood flow Valve problems can be present at birth or caused by infections, heart attacks, or heart disease or damage. [icdlist.com]

• Heart Disease

  BACKGROUND: In this study, we present a single center experience with Bicarbon bileaflet valve in 307 patients with rheumatic heart disease. [ncbi.nlm.nih.gov]

  Heart Valve Diseases Also called: Valvular heart disease Your heart has four valves. Normally, these valves open to let blood flow through or out of your heart, and then shut to keep it from flowing backward. But sometimes they don't work properly. [icdlist.com]

  Valve replacement; Valve repair; Heart valve prosthesis; Mechanical valves; Prosthetic valves Heart valve surgery is used to repair or replace diseased heart valves. [stlukes-stl.com]

• Heart Murmur

  The main sign of heart valve disease is an unusual heartbeat sound called a heart murmur. Your doctor can hear a heart murmur with a stethoscope. But many people have heart murmurs without having a problem. [icdlist.com]

  Yet some people may have heart murmurs without having heart valve disease. [verywell.com]

• Diastolic Murmur

  […] prosthetic valves: Low-grade systolic murmur (caged ball valves); short diastolic murmur (bioprostheses and, occasionally, St. [emedicine.medscape.com]

  On auscultation, valve clicks may be diminished or absent with additional systolic or diastolic murmurs. Detection of the “double click” may be useful for early diagnosis of dysfunction of bileaflet prostheses. [jtd.amegroups.com]

• Systolic Murmur

  […] prosthetic valves: Low-grade systolic murmur (caged ball valves); short diastolic murmur (bioprostheses and, occasionally, St. [emedicine.medscape.com]

• Withdrawn

  Withdrawn Application number EP19960931491 Other languages German ( de ) French ( fr ) Inventor Kurt D. Krueger Guy P. Vanney Current Assignee (The listed assignees may be inaccurate. [google.sr]

• Confusion

  Irregular heartbeat ( arrhythmia ) Kidney failure Post-pericardiotomy syndrome -- low fever and chest pain that can last for up to 6 months Stroke or other temporary or permanent brain injury Infection Problems with the breast bone healing Temporary confusion [stlukes-stl.com]

CONCLUSIONS: Our results emphasize the need for valve design changes, preoperative education about the sound, and inclusion of routine hearing tests into the preoperative workup. [ncbi.nlm.nih.gov]

[…] implantation (TAVI)/transcatheter aortic valve replacement (TAVR), except those in whom CT is contraindicated, [3, 4] and that the CT images should be interpreted with a member of the TAVI/TAVR team or reviewed with the operator before the procedure See Workup [emedicine.medscape.com]

Because of the twin problem of heart disease and anticoagulant therapy, treatment of abnormal vaginal bleeding in these women is extremely challenging. [ncbi.nlm.nih.gov]

Today’s treatments help more people than ever manage their arrhythmia and improve their quality of life. Learn about the different cardiac arrhythmias and their common treatments. [sjmglobal.com]

Outlook (Prognosis) The success rate of heart valve surgery is high. The operation can relieve your symptoms and prolong your life. Mechanical heart valves do not often fail. However, blood clots can develop on these valves. [stlukes-stl.com]

Long-term prognosis is generally benign in patients with mild paravalvular regurgitation identified by perioperative echocardiography, with progression of regurgitation requiring reoperation in 1 to 2 years. 78 Hence, closer follow-up appears justified [circ.ahajournals.org]

Mechanical valve dysfunction can be classified as endogenous and exogenous according to the etiology. [jtd.amegroups.com]

The mortality rate with a fungal etiology is 93%. The mortality rate for staphylococcal infections is 86%. PVE due to Staphylococcus has a mortality rate of 25-40%. [13, 14] Fatal anticoagulant-induced hemorrhage occurs in 0.5% of patients per year. [emedicine.medscape.com]

Piper C, Hering D, Langer C, Horstkotte D (2008) Etiology of stroke after mechanical heart valve replacement--results from a ten-year prospective study. J Heart Valve Dis 17: 413-417. [omicsonline.org]

Table 1 Age distribution 20 yrs ≧ 2 1 1 0 21–30 yrs 9 6 2 1 31–40 yrs 17 10 5 2 41–50 yrs 33 13 13 7 51–60 yrs 100 38 44 18 61–70 yrs 162 74 60 28 71–80 yrs 79 34 23 22 81–90 yrs 4 3 1 0 Table 2 Etiology of valve diseases aortic dissection 6 0 calcific [cardiothoracicsurgery.biomedcentral.com]

Epidemiology Frequency United States Prosthetic valve thrombosis is more common in mechanical valves. With proper anticoagulation, the rate of thrombosis in all valves is within the range of 0.1-5.7% per patient-year. [emedicine.medscape.com]

No significant differences were seen in major embolism or endocarditis. [11] Pathophysiology Valve failure Primary valve failure may occur abruptly from the tearing or breakage of components or from a thrombus suddenly impinging on leaflet mobility. [emedicine.medscape.com]

Abstract This study evaluated the advantage of an anticoagulation clinic in terms of the improvement of the clinical quality of oral anticoagulation (i.e. prevention of thromboembolism and low rate of hemorrhagic complications). [ncbi.nlm.nih.gov]