Presentation
Core genes were defined as present in ≥ 95% of genomes (combining the core and soft core from the Roary output), shell genes are present in ≥15% but Figure 3. [doi.org]
CLINICAL PRESENTATION Usually asymptomatic, but H. pylori is the major cause of peptic ulcer disease and gastritis worldwide, which present as gnawing or burning epigastric pain. Less commonly, symptoms include nausea, vomiting, or loss of appetite. [wwwnc.cdc.gov]
We present the long term outcome of a male bladder exstrophy patient after gastrocystoplasty. [ncbi.nlm.nih.gov]
Entire Body System
- Anemia
Gastrectomy was not performed, and following treatment, the ulcer, anemia, and poor growth resolved. Copyright 2015, SLACK Incorporated. [ncbi.nlm.nih.gov]
Iron deficiency anemia was diagnosed by measuring ferritin, iron and transferrin levels. [scla.org.sy]
a palpable mass or lymphadenopathy, melena, dysphagia, hematemesis, anemia, gastrointestinal bleeding, odynophagia, persistent vomiting or unintentional weight loss. [news.mayocliniclabs.com]
Read More In gastritis …anti-inflammatory drugs (NSAIDs), infection with Helicobacter pylori, or pernicious anemia. The symptoms are indefinite and often resemble those of functional digestive disorders. [britannica.com]
- Chronic Infection
Helicobacter pylori is one of the most common bacteria responsible for chronic infection worldwide. Its reservoir is essentially human. [ncbi.nlm.nih.gov]
- Collapse
However, due to weakness and numbness in his legs, he could not walk and collapsed to the ground. He presented to an outside hospital with paraplegia, and then he was transferred to a tertiary center for further management. [hindawi.com]
Some of this damage could result in DNA DSBs and replication fork collapse that require repair via DNA recombination processes. [iai.asm.org]
Since the Legionella T4SS system matches with the Cag system in terms of number of components, shape and appearance, it is likely that the Cag system also has a channel in situ and it collapsed during detergent purification to form the stalk density. [elifesciences.org]
- Surgical Procedure
[…] or iatrogenic etiologies including spinal surgeries, obstetrical birth trauma, lumbar puncture, spinal manipulations, and epidural procedures. [emedicine.medscape.com]
“Everyday” bacteremia is the real culprit: a review and assessment of the evidence that dental surgical procedures are a principal cause of bacterial endocarditis in children. Pediatr. Cardiol. 20, 317–325 (1999). 26. Falkow, S. [doi.org]
Gastrointestinal
- Dyspepsia
Non-ulcer dyspepsia This is a condition where you have recurrent bouts of indigestion (dyspepsia) which are not caused by an ulcer or inflammation. It is sometimes called functional dyspepsia. [patient.info]
BACKGROUND: The aim of this study was to evaluate the effect of Helicobacter pylori (H. pylori) eradication on dyspepsia symptom scores in children with functional dyspepsia (FD). [ncbi.nlm.nih.gov]
- Nausea
These illnesses are characterized by: upper abdominal pain; loss of appetite; nausea and vomiting; and if severe enough, bleeding into the gastrointestinal tract. [emedicinehealth.com]
Patients completed pre- and posttreatment questionnaires regarding symptoms (abdominal discomfort--pain, nausea, bloating), recent medications, and palatability. Nine patients completed the course of treatment and began follow-up testing. [ncbi.nlm.nih.gov]
Less commonly, symptoms include nausea, vomiting, or loss of appetite. Infected people have a 2- to 6-fold increased risk of developing gastric cancer and mucosal-associated-lymphoid-type (MALT) lymphoma compared with their uninfected counterparts. [wwwnc.cdc.gov]
Although many infected individuals have no symptoms, other infected individuals may have occasional episodes of belching, bloating, nausea and vomiting, and abdominal discomfort. [medicinenet.com]
The results showed that mean age ± Standard deviation for pregnant with vomiting and nausea (32.18 ± 1.8) and for pregnant without vomiting and nausea (8.7 ± 0.79). P.value < 0.05. [iasj.net]
- Vomiting
[…] of vomiting also dispersed H pylori into the air. [doi.org]
The organism is potentially transmissible during episodes of gastrointestinal tract illness, particularly with vomiting. [ncbi.nlm.nih.gov]
[…] abdominal pain, with or without vomiting or evidence of blood Anyone who has any of these symptoms should go to the emergency room right away. [ucsfhealth.org]
- Abdominal Pain
Bowel rest for 6 days relieved her abdominal pain and hematochezia. CONCLUSIONS: The present case developed AAHC caused by second-line therapy for H. pylori eradication. [ncbi.nlm.nih.gov]
pain without associated peptic ulcer disease.2 A meta-analysis found H. pylori was not associated with recurrent abdominal pain in children; there was conflicting evidence for an association with epigastric pain, and some evidence of association with [rch.org.au]
For example, gallbladder, liver, pancreas, and kidney ailments may have abdominal pain as the presenting symptom. Upper abdominal pain and nausea may be an atypical presentation of angina, or pain from coronary artery disease. [emedicinehealth.com]
It is unclear whether H. pylori infection without ulcers causes abdominal pain. [rileychildrens.org]
- Constipation
These drugs may cause diarrhea, constipation, and headache. Several different antibiotics may be used, including amoxicillin, clarithromycin, metronidazole, and tetracycline. [msdmanuals.com]
At enrollment, the patients will be informed of the common side effects from the studied antibiotics, including diarrhea, taste disturbance, nausea, bloating, loss of appetite, vomiting, abdominal pain, constipation, headache, and skin rash. [clinicaltrials.gov]
Differential diagnoses include parasite infection, lactose intolerance, constipation, liver dysfunction/hepatitis and coeliac disease, depending on area of origin. [rch.org.au]
As the malignancy progresses, symptoms may include: Persistent weakness and fatigue Bloating after meals Nausea and vomiting Difficulty swallowing Diarrhea or constipation Blood in stools or tarry stools Unexplained weight loss Vomiting of blood It [verywellhealth.com]
Liver, Gall & Pancreas
- Liver Dysfunction
Differential diagnoses include parasite infection, lactose intolerance, constipation, liver dysfunction/hepatitis and coeliac disease, depending on area of origin. [rch.org.au]
Cardiovascular
- Hypotension
Untreated and more severe infections have a worse prognosis because of the potential for bleeding, anemia, and low blood pressure (hypotension). What Is H. pylori, and Is It Contagious? H. pylori (Helicobacter pylori) are spiral shaped bacteria. [medicinenet.com]
Jaw & Teeth
- Halitosis
When signs or symptoms are present, they may include the following: Nausea Vomiting Heartburn Abdominal pain (most often in the central-upper area) Diarrhoea Hunger in the morning Halitosis (smelly mouth/breath) Staging of the Helicobacter Pylori infection [charlestownmedicalcentre.ie]
[…] stools (black color of feces due to bleeding ulcers) Fatigue Low red blood cell counts due to bleeding Full feeling after consuming a small amount of food Decreased appetite that is more constant Other symptoms may include: Diarrhea Heartburn Bad breath (halitosis [medicinenet.com]
Skin
- Purpura
Her major chronic illness was immune thrombocytopenic purpura (ITP) for which she had been treated with prednisone therapy for the past 15 years. [ncbi.nlm.nih.gov]
Henoch-Schönlein purpura Alopecia areata Sweet disease Systemic sclerosis Atopic dermatitis Behçet disease Generalised pruritus (itch) Nodular prurigo Immune thrombocytopenic purpura Lichen planus Aphthous ulceration. [dermnetnz.org]
Helicobacter pylori infection and immune thrombocytopenic purpura: an update. Helicobacter 2004 ; 9 : 342 –6. Fujimura K, Kuwana M, Kurata Y, et al. [doi.org]
Neurologic
- Irritability
It's also important to avoid giving your child aspirin, aspirin-containing medicines, ibuprofen, or anti-inflammatory drugs because these may irritate the stomach or cause stomach bleeding. [kidshealth.org]
H. pylori infection is treated with a combination of antibiotics to kill the bacteria, acid-blocking medications, and stomach lining protectors (bismuth medicines such as Pepto-Bismol) to help heal the ulcers and reduce irritation in the stomach and duodenum [gikids.org]
Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome PLoS ONE. 2010; 5(12) High Levels of Post-Abortion Complication in a Setting Where Abortion Service Is... [ncbi.nlm.nih.gov]
The first step is chronic gastritis (inflammation/irritation of the internal layers of the stomach lasting for at least 3 months), followed after a time by the second step, atrophic gastritis (thinning of the internal layers of the stomach, usually as [charlestownmedicalcentre.ie]
- Headache
Five patients discontinued treatment: 2 patients suffered from severe abdominal pain, one patient from headache, one patient from diarrhea, and one patient from diffuse urticarial rush. [ncbi.nlm.nih.gov]
At enrollment, the patients will be informed of the common side effects from the studied antibiotics, including diarrhea, taste disturbance, nausea, bloating, loss of appetite, vomiting, abdominal pain, constipation, headache, and skin rash. [clinicaltrials.gov]
These drugs may cause diarrhea, constipation, and headache. Several different antibiotics may be used, including amoxicillin, clarithromycin, metronidazole, and tetracycline. [msdmanuals.com]
[…] taste sensation Candida vaginitis Confusion Agitation Seizure Levofloxacin Diarrhoea Headache Nausea Arrhythmia Hypoglycaemia Hypersensitivity reaction Tendinitis Conclusion H. pylori infection remains a significant cause of morbidity worldwide. [racgp.org.au]
These include indigestion (dyspepsia), feeling sick (nausea), diarrhoea and headaches. However, it is worth persevering with the full course if side-effects are not too bad. [patient.info]
Workup
These findings also strengthen the importance of a gastroenterological workup of patients with CSU. © 2018 S. Karger AG, Basel. [ncbi.nlm.nih.gov]
[…] specimens from the gastric antrum and corpus and to perform a histologic examination on the obtained specimens Echography plus EGD: Mandatory in patients with positive biopsy results for gastric MALTomas to allow a more precise staging of the disease See Workup [emedicine.com]
This study changed the workup of all people with advanced gastric cancer since all people with advanced gastric cancer must now undergo HER‐2 testing before the initiation of any chemotherapy and, in the absence of contraindications, be treated with trastuzumab [doi.org]
Treatment
Gastroenterologists are advised to prescribe recommended salvage treatments, considering recommended dosages and prolonged treatment duration. © 2018 John Wiley & Sons Ltd. [ncbi.nlm.nih.gov]
What natural treatments cure H. pylori infection? There are many claims about natural treatment and cures for H. pylori infection. [medicinenet.com]
So, it is no use to confirm whether treatment has cleared the infection (if this needs to be known). If needed, the breath test or stool antigen test is usually used to check if an infection has cleared following treatment. [patient.info]
Prognosis
Therefore, we examined the prognosis of gastric cancer patients, diagnosed after successful H. pylori eradication therapy. [ncbi.nlm.nih.gov]
What is the prognosis for H. pylori infections? What if it is not treated? Many infections are mild and produce few, if any, symptoms. The prognosis of these infections is excellent. [medicinenet.com]
Etiology
The data concerning an etiologic role of H. pylori in duodenal ulcer are suggestive but not yet conclusive. Present antimicrobial therapy can suppress but usually cannot eliminate H. pylori. [ncbi.nlm.nih.gov]
Patients suffering from gastro-duodenal ulcers, the possibility of H. pylori infection as an etiological factor should be considered. Prevention of relapse of peptic ulcers in patients with H. pylori associated ulcers. [tr-ex.me]
This article reviews current concepts of peptic ulcer pathogenesis and therapy according to ulcer etiology; discusses potential interactions between etiologies; and considers the therapy forHpylori infection including the effects of antimicrobial resistance [citeseerx.ist.psu.edu]
Epidemiology
Much has been learned about biological and clinical aspects of H. pylori, but key epidemiologic questions have not been answered. [doi.org]
Electronic address: kr[email protected]. 2 Department of Infectious Disease Epidemiology, Imperial College London, London W2 1PG, United Kingdom. [ncbi.nlm.nih.gov]
To learn more about how we use cookies, please see our cookies policy Close Intended for healthcare professionals Education Epidemiology and... [bmj.bmjjournals.com]
Pathophysiology
Recent studies have shed light on the mechanism through which the cagA gene product, CagA, elicits pathophysiological actions. [ncbi.nlm.nih.gov]
We discuss the pathophysiology, causes, presentation, investigations, complications and management of stomach and duodenal ulcers. This video is for education and understanding only and is not medical advice. [youtube.com]
The pathophysiology of spontaneous hematomyelia is discussed. [thejns.org]
Sil, Unfolding the Mechanism of Proteases in Pathophysiology of Gastrointestinal Diseases, Pathophysiological Aspects of Proteases, 10.1007/978-981-10-6141-7_24, (583-603), (2017). [doi.org]
Prevention
Author information 1 State Key Laboratory for Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China Collaborative Innovation Center [ncbi.nlm.nih.gov]
However, if our results indicated that H. pylori vaccination was cost-effective for preventing gastric cancer, they could be assumed to underestimate the true CE, because benefits would also be realized from the prevention of DUs, dyspepsia, and MALT [doi.org]