An invasive infection was present in 3 patients who died soon after the diagnosis at 12, 13, and 45 days. Physicians should be mindful of this potential risk after treatment with voriconazole. [ncbi.nlm.nih.gov]

• Anemia

  Gov't Review MeSH terms Anemia, Dyserythropoietic, Congenital*/genetics Anemia, Dyserythropoietic, Congenital*/metabolism Anemia, Dyserythropoietic, Congenital*/pathology COP-Coated Vesicles/metabolism COP-Coated Vesicles/pathology* Factor V Deficiency [ncbi.nlm.nih.gov]

• Fatigue

  (ABCB7): early-onset spinocerebellar syndrome in males, manifest primarily as delayed walking, ataxia evident in early childhood, dysmetria, and dysdiadochokinesis >1/1,000,000 Early onset, rare late onset Sickle cell anemia HBB Shortness of breath, fatigue [centogene.com]

  Several of the most common are weakness, fatigue, shortness of breath, easy bruising and bleeding, frequent infections, enlarged lymph nodes, distended or painful abdomen (due to enlarged abdominal organs), bone or joint pain, fractures, unplanned weight [sharecare.com]

  However, rapid onset may result in symptoms of dyspnea, weakness and fatigue, and palpitations, reflecting the lack of oxygen transport to the lungs and muscles. Many people can have moderate-to-severe anemia without these symptoms. [musculoskeletalkey.com]

• Easy Bruising

  Platelet Disorders – (usually a deficiency in platelets leading to easy bruising and excessive bleeding) Immune Thrombocytopenic Purpura (ITP) – A clinical syndrome where a decreased number of platelets causes bleeding, and easy bruising. [nhoh.com]

  Several of the most common are weakness, fatigue, shortness of breath, easy bruising and bleeding, frequent infections, enlarged lymph nodes, distended or painful abdomen (due to enlarged abdominal organs), bone or joint pain, fractures, unplanned weight [sharecare.com]

  These conditions can result in low blood counts (anemia), low platelet counts (thrombocytopenia) and cause many symptoms, including shortness of breath, rapid heart rate, paleness, lack of energy and easy bruising. [mountsinai.org]

  On the other hand, easy bruising, a symptom suggestive of a blood disorder, can be caused by conditions other than a blood disorder, especially disorders of the blood vessels or the use of various drugs such as aspirin. [merckmanuals.com]

• Tachycardia

  […] usually normal in people with anemia, but cardiac output increases with exercise more than it does in people without anemia.9 As the anemia becomes more severe, resting cardiac output increases and exercise tolerance progressively decreases until dyspnea, tachycardia [musculoskeletalkey.com]

  […] recurrent bacterial and fungal infections, granuloma formation (pneumonia, lymphadenitis, liver abscess, osteomyelitis) 1:200,000 in US 1/111,000 in Israel Arabs 1/1,000,000 in Italy Early to late onset Hemolytic anemia G6PD, TPI1, CD59, KEL General pallor, tachycardia [centogene.com]

• Jaundice

  Age of onset: >1 year Dyserythropoietic anemia COX4I2, C15orf41, KIF23, KLF1 Moderate to severe macrocytic anemia presenting occasionally in utero as severe anemia associated with hydrops fetalis but more commonly in neonates as hepatomegaly, early jaundice [centogene.com]

  Jaundice and anemia c. Laboratory test: osmotic fragility test, cryohemolysis or EMA test e. [annexpublishers.co]

  Management Canadian Medical Association Journal Hemophilia A GeneClinics Hemophilia B GeneClinics Obstetrical management of von Willebrand's disease 2000 OBG Management Platelet Disorders Jaundice and DIC in Pregnancy Medscape Platelet disorders March [perinatology.com]

  • Jaundice. • Pica. • Infections. • Thrombocytopenia. • Drug history.  Detailed work history 5. PHYSICAL EXAMINATION  Pallor, jaundice, cyanosis.  Abnormal bleeding.  Infections.  Bone tenderness (sternum) 6. [slideshare.net]

  Hyperbilirubinemia and jaundice ineffective RBC formation and increased erythroblast destruction leads to excess bilirubin in the blood the waste product from breakdown of hemoglobin Neutropenia and thrombocytopenia decreased white cell count and decreased [quizlet.com]

• Petechiae

  Skin manifestations Petechiae (pinpoint red blood spots) Pinch purpura (blood spots as a result of stroking skin) Ecchymoses (flat bluish/purplish blood spots, larger than petechiae) Waxy induration of the skin Macroglossia (enlarged tongue) Skin signs [dermnetnz.org]

  Just a few examples include the following: Blood clot (phlebitis), usually in a leg (most often causing swelling, redness, and/or warmth of the leg or shortness of breath) Petechiae (a fine pin-point red skin rash) caused by too few platelets Blood blisters [merckmanuals.com]

  […] effusions 12-18% in Cyprus/Sardinia high in Medditeranean Fetal to adult onset Thrombocytopenia ANKRD26, MASTL, CYCS, ETV6, GATA1, ITGB3, ITGA2B, GATA1, WAS External bleeding (nosebleeds, bleeding gums), bruising, particularly purpura in the forearms, petechia [centogene.com]

• Localized Scleroderma

  The development of a serious hematologic disease, especially a lymphoproliferative process, may rarely be seen not only in patients with eosinophilic fasciitis but also in those with systemic or localized scleroderma. [ncbi.nlm.nih.gov]

Initial Diagnostic Workup of Acute Leukemia: Guideline From the College of American Pathologists and the American Society of Hematology. Arch Pathol Lab Med. 2017 Feb 22. [Medline]. [Full Text]. [medscape.com]

[…] antiphospholipid antibodies panel test (lupus anticoagulant, moderate or high titer anticardiolipin antibodies, and/or anti-b2GP1 antibodies) on 2 separate occasions at least 12 weeks apart, in the setting of thrombosis or pregnancy complications. 27 A workup [revespcardiol.org]

Definitive studies of the treatment of autoimmune thrombocytopenia and acute pulmonary disease and of the diagnosis and treatment of neuropsychiatric disease are not available. [ncbi.nlm.nih.gov]

From these variables, we derived a predictive model for the prognosis of febrile neutropenia using baseline serum albumin, bicarbonate, and CRP, which could be easily checked before chemotherapy. [ncbi.nlm.nih.gov]

Scientific articles from MEDLINE for "Hematologic Diseases" - English - French - German - Spanish - Portuguese - Italian - Dutch All recent articles Therapy: by recall / by precision Diagnosis: by recall / by precision Etiology: by recall / by precision Prognosis [hon.ch]

Idiopathic pneumonia syndrome after HSCT IPS has a grave prognosis, and the requirement for mechanical ventilation confers a particularly poor prognosis. [clinicaladvisor.com]

by recall / by precision Prognosis: by recall / by precision Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Browse - New search Clinical Trials for "Hematologic Diseases" [hon.ch]

Thrombocytopenia Thrombocytopenic purpura may be idiopathic (i.e., of unknown etiology, as in VVerlhof's disease), or it may occur secondary to some known etiologic factor responsible lor a reduc tion in the amount of functioning marrow and a resultant [clicktocurecancer.info]

[…] blood supply cerebrospinal fluid chemical synthesis chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug effects drug therapy economics embryology enzymology epidemiology ethnology etiology [ncbi.nlm.nih.gov]

“Anemia at older age: etiologies, clinical implications, and management” by Reinhard Stauder, Peter Valent, and Igor Theurl. [ashpublications.org]

DESIGN AND METHODS: To define sources and clinical courses of HCV infection, an epidemiologic study was performed on 13 patients newly admitted over one year who showed transaminase elevation and anti-HCV seroconversion. [ncbi.nlm.nih.gov]

Consult HON's world-wide database of medical meetings Browse - New search Refine the search for "Hematologic Diseases" Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Broader [hon.ch]

The presence of Philadelphia chromosome does not confer poor prognosis in adult pre-B acute lymphoblastic leukaemia in the tyrosine kinase inhibitor era - a surveillance, epidemiology, and end results database analysis. [medscape.com]

Additionally, it is important for urologists to understand the underlying pathophysiology of hematologic disease to best serve the patients. [ncbi.nlm.nih.gov]

What you will learn about rare hematologic disorders: Strategies to improve your differential diagnosis skills Relevance of the pathophysiology and biology to the management of these disorders State-of-the-art treatment approaches and treatment-related [gotoper.com]

Research interests may include an area of applied genomics of disease of the hematological system, including but not limited to the following: molecular signaling of blood cells, bone marrow biology, and pathophysiology, molecular cytogenetics, genes [jobs.sciencecareers.org]

First, I spoke briefly about the complement pathway and some of the diseases, particularly hemolytic anemias that have pathogenesis or pathophysiology related to the complement pathway, and how current research and even clinical practice is utilizing [onclive.com]

Our ability to treat and prevent these complications will improve as our understanding of these disease processes and their pathophysiology grows. [ncbi.nlm.nih.gov]

Blood diseases and disorders affect one or more parts of the blood and prevent your blood from doing its job. Many blood diseases and disorders are caused by genes. [hematologic.niddk.nih.gov]

Hematology is the branch of medicine concerned with the study of the prevention, cause, diagnosis, and treatment of diseases related to blood. Hematologic diseases are disorders which primarily affect the blood. [imedpub.com]

Cancer Research Georgetown Lombardi's world-renowned Research Faculty are discovering cancer risk factors, designing effective prevention strategies, and learning how to detect cancers earlier. [lombardi.georgetown.edu]