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Hematologic Disease

Blood Disease


Presentation

  • An invasive infection was present in 3 patients who died soon after the diagnosis at 12, 13, and 45 days. Physicians should be mindful of this potential risk after treatment with voriconazole.[ncbi.nlm.nih.gov]
  • In this review we will summarize the role of coagulation in the pathophysiology of renal disease and present renal involvement in sickle cell anemia, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, leukemia, and other less common hematologic[ncbi.nlm.nih.gov]
  • Splenic involvement by peliosis was present in both patients.[ncbi.nlm.nih.gov]
  • We conclude that splenectomy is sufficiently well tolerated even by severely ill patients to make it applicable as a therapeutic modality in the various hematologic disorders presently studied.[ncbi.nlm.nih.gov]
  • Splenectomy also serves as a staging tool in lymphoma, Hodgkin's disease, and NHL, although it is much more beneficial in Hodgkin's disease, owing simply to stage at presentation.[ncbi.nlm.nih.gov]
Anemia
  • The anemia of chronic renal failure and of acquired immunodeficiency syndrome has responded to treatment with recombinant human erythropoietin.[ncbi.nlm.nih.gov]
  • Splenectomy for hypoplastic or aplastic anemia in an actual circulation offered only questionable benefit and is rarely necessary for hyperplenism secondary to portal hypertension.[ncbi.nlm.nih.gov]
  • CONCLUSIONS: It is possible that a relatively large number of patients with pure red cell aplasia, multiple myeloma or aplastic anemia will develop a colorectal cancer.[ncbi.nlm.nih.gov]
  • Gov't Review MeSH terms Anemia, Dyserythropoietic, Congenital*/genetics Anemia, Dyserythropoietic, Congenital*/metabolism Anemia, Dyserythropoietic, Congenital*/pathology COP-Coated Vesicles/metabolism COP-Coated Vesicles/pathology* Factor V Deficiency[ncbi.nlm.nih.gov]
  • In one patient with spherocytic hemolytic anemia, peliosis hepatis was an incidental postmortem finding.[ncbi.nlm.nih.gov]
Tachycardia
  • […] recurrent bacterial and fungal infections, granuloma formation (pneumonia, lymphadenitis, liver abscess, osteomyelitis) 1:200,000 in US 1/111,000 in Israel Arabs 1/1,000,000 in Italy Early to late onset Hemolytic anemia G6PD, TPI1, CD59, KEL General pallor, tachycardia[centogene.com]
Jaundice
  • Jaundice and anemia c. Laboratory test: osmotic fragility test, cryohemolysis or EMA test e.[annexpublishers.co]
  • […] granuloma formation (pneumonia, lymphadenitis, liver abscess, osteomyelitis) 1:200,000 in US 1/111,000 in Israel Arabs 1/1,000,000 in Italy Early to late onset Hemolytic anemia G6PD, TPI1, CD59, KEL General pallor, tachycardia, tachypnea, hypotension, jaundice[centogene.com]
  • Hyperbilirubinemia and jaundice ineffective RBC formation and increased erythroblast destruction leads to excess bilirubin in the blood the waste product from breakdown of hemoglobin Neutropenia and thrombocytopenia decreased white cell count and decreased[quizlet.com]
  • Management Canadian Medical Association Journal Hemophilia A GeneClinics Hemophilia B GeneClinics Obstetrical management of von Willebrand's disease 2000 OBG Management Platelet Disorders Jaundice and DIC in Pregnancy Medscape Platelet disorders March[perinatology.com]
  • Symptoms of these conditions include: Anemias and hemoglobinopathies: Pale complexion or a yellow complexion, known as jaundice; fatigue Erythrocytosis: Red complexion Histiocytic disorders: Non-specific conditions that can be similar to anemia, thrombocytopenia[mdanderson.org]
Petechiae
  • Petechiae were the most common skin manifestation (58.3%) followed by noninflammatory retiform purpura (33.3%) [Figure 1] and hematoma (16.6%). The average platelet count in patients with petechiae was 48,000/mm 3 (range, 40,000-74,000/mm 3 ).[idoj.in]
  • Patients may report a history of easy bruising and petechiae or epistaxis and gingival bleeding preceding the pregnancy.[www1.cgmh.org.tw]
  • Just a few examples include the following: Blood clot (phlebitis), usually in a leg (most often causing swelling, redness, and/or warmth of the leg or shortness of breath) Petechiae (a fine pin-point red skin rash) caused by too few platelets Blood blisters[merckmanuals.com]
  • […] effusions 12-18% in Cyprus/Sardinia high in Medditeranean Fetal to adult onset Thrombocytopenia ANKRD26, MASTL, CYCS, ETV6, GATA1, ITGB3, ITGA2B, GATA1, WAS External bleeding (nosebleeds, bleeding gums), bruising, particularly purpura in the forearms, petechia[centogene.com]
  • Orofacial petechiae, conjunctivae hemorrhage, nose-bleeding, spontaneous and post-traumatic gingival hemorrhage and prolonged post-extraction bleeding are common orofacial manifestations of inherited hemostatic disorders such as von Willebrand's disease[ijdr.in]
Localized Scleroderma
  • The development of a serious hematologic disease, especially a lymphoproliferative process, may rarely be seen not only in patients with eosinophilic fasciitis but also in those with systemic or localized scleroderma.[ncbi.nlm.nih.gov]

Treatment

  • LM may be a safe method of treatment of PMH in children in selected cases.[ncbi.nlm.nih.gov]
  • Definitive studies of the treatment of autoimmune thrombocytopenia and acute pulmonary disease and of the diagnosis and treatment of neuropsychiatric disease are not available.[ncbi.nlm.nih.gov]
  • Therefore, this report provides a comprehensive review of the osteonecrosis treatment options and results across the spectrum of patients who have various hematologic disorders.[ncbi.nlm.nih.gov]
  • Patients who developed PVT were also reviewed for clinical features, treatment modalities, and outcome.[ncbi.nlm.nih.gov]
  • The anemia of chronic renal failure and of acquired immunodeficiency syndrome has responded to treatment with recombinant human erythropoietin.[ncbi.nlm.nih.gov]

Prognosis

  • From these variables, we derived a predictive model for the prognosis of febrile neutropenia using baseline serum albumin, bicarbonate, and CRP, which could be easily checked before chemotherapy.[ncbi.nlm.nih.gov]
  • Many studies have shown that estimates of prognosis are enhanced by consideration of clinical, demographic, and histologic features.[ncbi.nlm.nih.gov]
  • Scientific articles from MEDLINE for "Hematologic Diseases" - English - French - German - Spanish - Portuguese - Italian - Dutch All recent articles Therapy: by recall / by precision Diagnosis: by recall / by precision Etiology: by recall / by precision Prognosis[hon.ch]
  • Abstract ETV6/CBFA2 (TEL/AML1) is the most frequent genetic abnormality associated with acute lymphoblastic leukemias in children, and is associated with a favorable prognosis.[ncbi.nlm.nih.gov]
  • Recurrence rate was 66.6% in the study group as against 14.2% in the control group, indicating poor prognosis of LCV in cases associated with hematologic disorders.[idoj.in]

Etiology

  • A systematic approach to these etiologies is important.[ncbi.nlm.nih.gov]
  • : by recall / by precision Prognosis: by recall / by precision Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Browse - New search Clinical Trials for "Hematologic Diseases"[hon.ch]
  • […] blood supply cerebrospinal fluid chemical synthesis chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug effects drug therapy economics embryology enzymology epidemiology ethnology etiology[ncbi.nlm.nih.gov]
  • Journal of Blood Research & Hematologic Diseases focuses on the topics include: Hematology Blood cells Genetics of Blood Cells Blood Physiology Blood Disorders & Diseases Etiology of Blood Pathophysiology of Blood Disorders Blood Malignancies Blood-based[scitechnol.com]
  • Its etiology comes from genetic alterations of membrane and structural proteins which disturb the erythrocyte cohesion and stability.[annexpublishers.co]

Epidemiology

  • DESIGN AND METHODS: To define sources and clinical courses of HCV infection, an epidemiologic study was performed on 13 patients newly admitted over one year who showed transaminase elevation and anti-HCV seroconversion.[ncbi.nlm.nih.gov]
  • Consult HON's world-wide database of medical meetings Browse - New search Refine the search for "Hematologic Diseases" Subheadings: complications / diagnosis / embryology / epidemiology / etiology / metabolism / microbiology / surgery / therapy Broader[hon.ch]
  • […] biosynthesis blood blood supply cerebrospinal fluid chemical synthesis chemically induced chemistry classification complications congenital cytology diagnosis diagnostic imaging diet therapy drug effects drug therapy economics embryology enzymology epidemiology[ncbi.nlm.nih.gov]
  • Epidemiological investigation of the prevalence of von Willebrand's disease. Blood 1987;692:454-9. 53. Miller CH, Graham JB, Goldin LR, Elston RC. Genetics of classic von Willebrand's disease: I. Phenotypic variation within families.[ijdr.in]
Sex distribution
Age distribution

Pathophysiology

  • Additionally, it is important for urologists to understand the underlying pathophysiology of hematologic disease to best serve the patients.[ncbi.nlm.nih.gov]
  • In this review we will summarize the role of coagulation in the pathophysiology of renal disease and present renal involvement in sickle cell anemia, hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, leukemia, and other less common hematologic[ncbi.nlm.nih.gov]
  • Journal of Blood Research & Hematologic Diseases focuses on the topics include: Hematology Blood cells Genetics of Blood Cells Blood Physiology Blood Disorders & Diseases Etiology of Blood Pathophysiology of Blood Disorders Blood Malignancies Blood-based[scitechnol.com]
  • First, I spoke briefly about the complement pathway and some of the diseases, particularly hemolytic anemias that have pathogenesis or pathophysiology related to the complement pathway, and how current research and even clinical practice is utilizing[onclive.com]
  • The following algorithms are available in Special Instructions: -Aggressive B-cell Lymphoma Diagnostic Algorithm in Special Instructions -B-Lymphoblastic Leukemia/Lymphoma Algorithm Clinical Information Discusses physiology, pathophysiology, and general[mayomedicallaboratories.com]

Prevention

  • Our ability to treat and prevent these complications will improve as our understanding of these disease processes and their pathophysiology grows.[ncbi.nlm.nih.gov]
  • Blood diseases and disorders affect one or more parts of the blood and prevent your blood from doing its job. Many blood diseases and disorders are caused by genes.[hematologic.niddk.nih.gov]
  • After having analyzed all the possible routes of transmission, a series of preventive measures were adopted: search for HCV RNA in newly admitted patients, protection of mucosae and isolation of patients during neutropenic phases, and avoidance of multidose[ncbi.nlm.nih.gov]
  • Any disturbance or disorders that prevent the blood to function properly may affects total health. Blood disorders affect one or more parts of the blood, which can be acute or chronic.[scitechnol.com]
  • The Iron Disorders Institute provides information about iron disorders as well as preventions, publications, diet suggestions, and more.[nhoh.com]

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