One of the hallmarks of dysostosis multiplex in MPS I-H is hip dysplasia, which often requires surgical intervention. [ncbi.nlm.nih.gov]

[…] complications occurred in the post-transplantation phase, including acute graft versus host disease, posterior reversible encephalopathy, thrombotic thrombocytopenic purpura, bilateral keratoconjunctivitis with complete loss of vision, and chronic lower limb lymphedema [ncbi.nlm.nih.gov]

Despite acyclovir prophylaxis (200 mg/day), she developed the right palatal ulcer that was positive for HSV-1 specific antigen by fluorescent antibody on day 20 and developed new hypoglossal and tongue ulcers on day 33. [ncbi.nlm.nih.gov]

The human MHC is located on the short arm of chromosome 6 and contains a series of genes encoding two distinct types of highly polymorphic cell surface glycoproteins. [ncbi.nlm.nih.gov]

These antigens are also known as the major histocompatibility complex (MHC) and occupy the short arm of chromosome 6. [80] This genetic region has been divided into chromosomal regions, called classes. [emedicine.medscape.com]

Giralt, Deletion of the Short Arm of Chromosome 1 (del 1p) is a Strong Predictor of Poor Outcome in Myeloma Patients Undergoing an Autotransplant, Biology of Blood and Marrow Transplantation, 13, 9, (1066), (2007). [dx.doi.org]

Our study shows that progressive acetabular dysplasia as well as coxa valga and hip displacement are highly prevalent and progressive over time in patients with MPS I-H, despite successful HSCT. [ncbi.nlm.nih.gov]

Dry eye was diagnosed in 14 out 46 hematological patients (30.4%). [ncbi.nlm.nih.gov]

Keratoconjunctivitis sicca, or dry eyes, is part of chronic GVHD syndrome. Other adverse effects include retinopathy, infectious retinitis, and hemorrhage. [emedicine.medscape.com]

Other important symptoms that should be assessed include dry eyes and oral changes such as atrophy, ulcers, and lichen planus. [cancer.gov]

Potential side effects: Nausea, vomiting and diarrhea Lowers blood counts Hair loss Irritation and sores in the mouth and intestinal tract Damage to the liver Drowsiness blurred vision May sensitize the skin to sunlight Tacrolimus (FK506) What it does [ucsfbenioffchildrens.org]

He developed painless right testicular swelling after nearly 3 years since the ASCT. After radical orchiectomy, histopathology showed diffuse abnormal plasma cells infiltration of the testicular tissue. [ncbi.nlm.nih.gov]

Parkinsonism symptoms such as muscle rigidity, bradykinesia, tremor, and postural instability were initial manifestations. Magnetic resonance imaging showed diffuse symmetrical lesions of bilateral basal ganglia lacking ringed enhancement. [ncbi.nlm.nih.gov]

Parkinsonism symptoms such as muscle rigidity, bradykinesia, tremor, and postural instability were initial manifestations. Magnetic resonance imaging showed diffuse symmetrical lesions of bilateral basal ganglia lacking ringed enhancement. [ncbi.nlm.nih.gov]

Dyslipidemia was associated with a primary diagnosis of hematological malignancy, TBI, and a positive family history of dyslipidemia. Endocrine dysfunction was less frequent in patients who had received fludarabine. [ncbi.nlm.nih.gov]

Survivors also had an increased cumulative incidence of related conditions that predispose towards more serious cardiovascular disease (i.e., hypertension, renal disease, dyslipidemia, and diabetes).[ 13 ] In addition, cardiac function and pre-HCT exposures [cancer.gov]

CASE PRESENTATION: Clinical and laboratory investigations were performed for an 11-year-and-2-month-old girl who was referred for bilateral exophthalmus and abnormal thyroid function tests. [ncbi.nlm.nih.gov]

KEYWORDS: Toxoplasma gondii ; hematopoietic stem cell transplantation; parkinsonism [ncbi.nlm.nih.gov]