Weiner, Bernard Gonik, Caroline Crowther, and Stephen Robson present an evidence-based approach to the available management options, equipping you with the most appropriate strategy for each patient. [books.google.com]

Fortunately, this is a rare event with present obstetrical management. If present, ascites may create ventilatory embarrassment and paracentesis should be considered. [uichildrens.org]

Abstract Hemolytic disease of the fetus and newborn (HDFN) is the result of immune-mediated destruction of fetal or newborn red blood cells when such cells contain antigens that are not present in the maternal blood. [hw-f5-neoreviews.highwire.org]

In the present case, the intervening laboratory staff prevented repetitive transfusion of an incompatible RBC unit even though the initial workup was misled by the negative DAT. [pubs.sciepub.com]

Fetal blood group was A-positive and was negative in workup for non-immune hydrops. Maternal serum indirect Coomb's test was positive, thus leading to a suspicion of the presence of non-anti-D antibodies. [jmedicalcasereports.biomedcentral.com]

PMID 7655573. a b c Hemolytic Disease of Newborn workup at eMedicine [ full citation needed ] a b c American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. (2004). [en.wikipedia.org]

Make informed clinical choices for each patient, from diagnosis and treatment selection through post-treatment strategies and management of complications, with new evidence-based criteria throughout. [books.google.com]

Early recognition and antenatal management may help to improve the prognosis. [medcaretips.com]

The scenario is different in most of the developing countries such as India, where red cell transfusions are matched only for ABO and RhD. [8] Although the incidence of Kell alloimmunization is observed to be low, the prognosis is poor in such pregnancies [gjtmonline.com]

HISTORY Haemolytic disease of the newborn (HDN) has been known for centuries with its typical and poor prognosis. The first described by a French midwife who delivered twins in 1609. [slideshare.net]

2009) 2.2 PROGNOSIS The severity of this condition can vary. Some babies have no symptoms. In other cases, problems such as hydrops can cause the baby to die before, or shortly after birth. [fruittyblog.blogspot.com]

In the largest retrospective review on the etiology of hydrops [ 6 ] involving 598 patients, the cause of hydrops was established unclearly in 26.3% of cases, isoimmunisation in 4.5% of cases, and non-immune etiology in 69.2% of cases. [jmedicalcasereports.biomedcentral.com]

Although anti-RhD was once the major etiology of hemolytic disease of the fetus/newborn (HDFN), the widespread adoption of antenatal and postpartum Rhesus immune globulin has resulted in a marked decrease in the prevalence of alloimmunization to the RhD [scienceopen.com]

The etiology was cleared retrospectively, since the baby subsequently died. In a second fatal case presenting a hydropic stillborn, anti-c was implicated as provoking HDFN as other causes of non-immune hydrops could be excluded. [pubs.sciepub.com]

Treatment of hemolytic disease The goal of any therapy is to treat the etiology of the disease using the most effective but least invasive method. [dovepress.com]

Am J Hematol 87:525–528 CrossRef PubMed Google Scholar Bellini C, Hennekam RC, Fulcheri E, Rutigliani M, Morcaldi G, Boccardo F, Bonioli E (2009) Etiology of nonimmune hydrops featlis: a systematic review. [link.springer.com]

Abstract Introduction The objective of the analysis was to examine the epidemiological aspects of maternal alloimmunization and to determine the most common antibody specificities resulting in hemolytic disease of the newborn (HDN). [thieme-connect.de]

History / Epidemiology In 1609, a French midwife first described HDN, in a set of twins—one baby was markedly edematous and died soon after birth, the second baby developed jaundice and died several days later [ 1 ]. [omicsonline.org]

"Epidemiology of cerebral palsy". Seminars in Fetal and Neonatal Medicine. 11 (2): 117–25. doi : 10.1016/j.siny.2005.10.010. PMID 16338186. Lande, Lottie (1948). "Clinical signs and development of survivors of kernicterus due to Rh sensitization". [en.wikipedia.org]

Epidemiology of Rh haemolytic disease of the new-born in the United States. Journal of American Medical Association; 265 (24):3270-3274. Cohen, D. W. (2009). [fruittyblog.blogspot.com]

Nathan and Oski’s is the only comprehensive product on the market that relates pathophysiology in such depth to hematologic and oncologic diseases affecting children. [books.google.com]

Pathophysiology Hemolytic disease of the newborn (anti-Kell 1 is caused by a mis-match between the Kell antigens of the mother and fetus. About 91% of the population are Kell 1 negative and about 9% are Kell 1 positive. [wikidoc.org]

It includes a review of historical perspective, pathophysiology of RBC antigen iso-sensitization, hydrops fetalis, clinical presentation, and management of HDN. [omicsonline.org]

Pathophysiology of Hemolytic Disease of Newborn During first pregnancy, senstization of Rhnegative mother to Rh-positive red cells occurs as a result of symptomatic fetomaternal hemorrhage during pregnancy. [medcaretips.com]

[…] can occur following: incompatible blood transfusions previous fetal-maternal hemorrhage (ie ectopic pregnancy, abortion) procedures (amniocentesis, cerclage, D&C) sharing needles labour and delivery naturally occurring (ie Kell, Duffy) return to top Pathophysiology [sharinginhealth.ca]

PREVENTION Rh Immune Globulin (RhIG or Rhogam) • Alloimmunization in pregnant woman can be prevented by administration of Rh immune globulin (RhIG or Rhogam). • RhIG is a concentrate of IgG anti-D prepared from pooled human plasma of D-negative people [slideshare.net]

Anti-Kell 1 is becoming relatively more important as prevention of Rh disease is becoming more and more effective. [wikidoc.org]

It has been hypothesized that IgG anti-Kell 1 antibody injections would prevent sensitization to RBC surface Kell 1 antigens in a similar way that IgG anti-D antibodies ( Rho(D) Immune Globulin ) are used to prevent Rh disease, but the methods for IgG [ipfs.io]

Preventing rhesus disease Rhesus disease is uncommon these days because it can usually be prevented using injections of a medication called anti-D immunoglobulin. [nhs.uk]

This prevents adverse reactions for the mother if any of the baby’s placenta remains in the womb. [healthline.com]