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Hemorrhagic Disease Due to Alpha-1-Antitrypsin Pittsburgh Mutation

Presentation

Patients present with spontaneous hematomas, hematomas following minor trauma or surgery and in female patients ovarian hematomas after ovulation. [from SNOMEDCT_US] Diagnosis Haematologica 2009 Jun;94(6):881-4. doi: 10.3324/haematol.2008.004739. [ncbi.nlm.nih.gov]

Treatment

Accessed September 28, 2021. https://www.alpha1.org/healthcare-providers/testing-and-treatment/diagnosing-alpha-1/ Alpha-1 Foundation. Testing for alpha-1. Date unknown. [labtestsonline.it]

Prognosis

PMID: 19483159Free PMC Article Prognosis Owen MC, Brennan SO, Lewis JH, Carrell RW N Engl J Med 1983 Sep 22;309(12):694-8. doi: 10.1056/NEJM198309223091203. [ncbi.nlm.nih.gov]

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