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Hemorrhagic Stroke

Haemorrhagic Stroke


Presentation

  • We present the case of an 89-year-old woman with no previous cardiovascular disease who presented a stress cardiomyopathy secondary to acute hemorrhagic stroke.[ncbi.nlm.nih.gov]
  • MESSAGE: Clinician must be aware regarding this rare presentation of tuberous sclerosis.[ncbi.nlm.nih.gov]
  • The female patient described in the present study reported that faces she looked at seemed younger or older than in reality or as if they were dirty, swollen, or with a grimace.[ncbi.nlm.nih.gov]
  • Although primary and metastatic brain tumors can cause intracranial hemorrhage, thalamic hemorrhage as the first presentation of an anaplastic astrocytoma has not been reported.[ncbi.nlm.nih.gov]
  • Older children with cerebral AVF tend to present with neurologic problems related to intracranial venous hypertension or intracranial hemorrhage.[ncbi.nlm.nih.gov]
Weakness
  • A 12-year-old previously healthy male, with a family history of protein S deficiency, presented with confusion, aphasia, and right upper extremity weakness after a 10-day febrile illness.[ncbi.nlm.nih.gov]
  • OUTCOME: Weakness gradually improved. Follow-up neuroimaging showed resolution of hemorrhage. MESSAGE: Clinician must be aware regarding this rare presentation of tuberous sclerosis.[ncbi.nlm.nih.gov]
  • He showed no significant motor or intelligence impairment in adolescence until he was hospitalized for transient left had tremors and slight left hand weakness caused by a cyst.[ncbi.nlm.nih.gov]
  • There were weak correlations between FXII and body mass index, cholesterol, and hypertension.[ncbi.nlm.nih.gov]
  • Symptoms include sudden tingling, weakness, numbness, paralysis, severe headache, difficulty with swallowing or vision, loss of balance or coordination, difficulty understanding, speaking , reading, or writing, and a change in level of consciousness or[my.clevelandclinic.org]
Vomiting
  • Typical clinical symptoms of hemorrhagic stroke after spine and joint surgeries include headache, vomiting, consciousness disturbance, and mental disorders. It can happen several hours after surgeries.[ncbi.nlm.nih.gov]
  • Immediately following Epley maneuver, she had severe nausea and vomiting, with evolving visual changes.[ncbi.nlm.nih.gov]
  • If you have a hemorrhagic stroke caused by a slow accumulation of blood, you may experience symptoms such as headaches, lethargy, and nausea or vomiting.[mountsinai.org]
  • […] likelihood ratio [LR], 6.2; 95% confidence interval [CI], 3.2-12), neck stiffness (LR, 5.0; 95% CI, 1.9-12.8), seizures accompanying the neurologic deficit (LR, 4.7; 95% CI, 1.6-14), diastolic blood pressure greater than 110 mm Hg (LR, 4.3; 95% CI, 1.4-14), vomiting[ncbi.nlm.nih.gov]
  • Depending on the location and amount of bleeding in the brain, ICH symptoms may include: Partial or total loss of consciousness Vomiting or severe nausea, when combined with other symptoms Sudden numbness or weakness of face, arm or leg, especially on[pacificneuroscienceinstitute.org]
Nausea
  • Immediately following Epley maneuver, she had severe nausea and vomiting, with evolving visual changes.[ncbi.nlm.nih.gov]
  • If you have a hemorrhagic stroke caused by a slow accumulation of blood, you may experience symptoms such as headaches, lethargy, and nausea or vomiting.[mountsinai.org]
  • Depending on the location and amount of bleeding in the brain, ICH symptoms may include: Partial or total loss of consciousness Vomiting or severe nausea, when combined with other symptoms Sudden numbness or weakness of face, arm or leg, especially on[pacificneuroscienceinstitute.org]
  • Clinical signs and symptoms of intracerebral hemorrhage Acute onset with local signs, according to the location and size of the hematoma (hemiparesis, hemihypoesthesia, cerebellar syndrome)  Diffuse neurologic signs (headache, nausea/vomiting), Loss[slideshare.net]
  • Sudden, severe headache, nausea, vomiting, stiffness in the neck , sensitivity to light and loss of consciousness may be seen.[epainassist.com]
Protein S Deficiency
  • A 12-year-old previously healthy male, with a family history of protein S deficiency, presented with confusion, aphasia, and right upper extremity weakness after a 10-day febrile illness.[ncbi.nlm.nih.gov]
Benign Paroxysmal Positional Vertigo
  • This is the first case to our knowledge of a serious adverse event following the Epley maneuver, which is the treatment of choice for benign paroxysmal positional vertigo (BPPV), the most common vestibular disorder in adults.[ncbi.nlm.nih.gov]
Headache
  • Possible roles of preexisting migrainous headaches and perioperative ephedrine are discussed, but, as in most cases of perioperative stroke, the possibilities are numerous and the cause of the stroke difficult to determine.[ncbi.nlm.nih.gov]
  • This is a case report of a 44-year-old man, without previous morbidities, who presented a sudden onset headache and arterial hypertension 24 hours after use of naphazoline as nasal decongestant. Cranial tomography showed right thalamus hemorrhage.[ncbi.nlm.nih.gov]
  • She required vasopressor therapy for intraoperative hypotension and developed severe headache immediately after administration.[ncbi.nlm.nih.gov]
  • Many people have described this as the “worst headache of your life.”[mountsinai.org]
  • He was hospitalized because of a sudden onset of headache, right hemiparesis, and dysarthria. A computed tomography scan revealed an intracerebral hemorrhage in the left parietal lobe.[ncbi.nlm.nih.gov]
Slurred Speech
  • The signs of a stroke include a sudden severe headache, weakness, numbness, vision problems, confusion, trouble walking or talking, dizziness and slurred speech.[webmd.com]
  • You may have experienced some of the following symptoms: Numbness in the arms or legs Partial paralysis Slurred speech Speech loss Blurred vision Temporary blindness in one eye Extreme fatigue Coordination problems Stiff muscles Poor balance Headache[neurosurgeonsofnewjersey.com]
  • Slurred speech or dysarthria Double vision or other vision problems A headache Nausea and or vomiting 2017 Fast Parody Video When it comes to spotting stroke and getting help, the faster, the better.[strokeassociation.org]
  • speech, trouble trying to speak, inability to speak at all, or difficulty in understanding simple directions Trouble seeing clearly in one or both eyes Severe dizziness or unsteadiness that may lead to losing balance or falling In newborns and infants[chop.edu]
Spastic Quadriplegia
  • In the follow-up, the infant developed spastic quadriplegia and showed delayed milestones. We believe that this is the first reported case of neonatal lupus accompanied by perinatal hemorrhagic stroke.[ncbi.nlm.nih.gov]

Workup

  • (See Workup.) Axial noncontrast computed tomography scan of the brain of a 60-year-old man with a history of acute onset of left-sided weakness.[emedicine.medscape.com]
  • [straitstimes.com] Workup Brain imaging is the single most important tool to assess cerebrovascular accidents.[symptoma.com]

Treatment

  • Resumption of warfarin treatment was evaluated after hospital discharge. Exposures: No oral anticoagulant treatment or resumption of warfarin treatment, included as a time-dependent exposure.[ncbi.nlm.nih.gov]
  • The adjusted risk associated with persistent warfarin treatment compared to no antithrombotic treatment consistently showed no increased HS risk, HR for women 0.53 (95 % CI 0.23-1.27) and for men 0.55 (95 % CI 0.29-1.04); corresponding HRs for ASA were[ncbi.nlm.nih.gov]
  • The objective of this study was to compare short-term mortality and safety outcomes between the two treatments using a large national database.[ncbi.nlm.nih.gov]
  • BACKGROUND: Previous studies have identified various treatment and patient characteristics that may be associated with higher hospital cost after spontaneous intracerebral hemorrhage (ICH); a devastating type of stroke.[ncbi.nlm.nih.gov]
  • Neuroimaging studies are integral to the identification of hemorrhagic stroke, determination of the underlying etiology, prevention of hematoma expansion, treatment of acute complications, and treatment of the underlying etiology, if indicated.[ncbi.nlm.nih.gov]

Prognosis

  • The associations of MPV and PLT count with the occurrence and prognosis of stroke have not been fully clarified.[ncbi.nlm.nih.gov]
  • CONCLUSION: MMP-9 is involved in the pathological process of hemorrhagic stroke through a variety of mechanisms and is closely related to prognosis after cerebral hemorrhagic stroke.[ncbi.nlm.nih.gov]
  • KEYWORDS: Senegal; hemorrhagic stroke; prognosis; young people [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov]
  • Although the frequency of hemorrhagic stroke was only 2.1% among adults with acute BM, it is a major determinant of prognosis for such patients.[ncbi.nlm.nih.gov]
  • Several patients need a hematoma evacuation and their prognosis is not optimistic.[ncbi.nlm.nih.gov]

Etiology

  • This study investigated the clinical manifestations and outcomes of perinatal stroke and identified its etiologies in Taiwan.[ncbi.nlm.nih.gov]
  • Neuroimaging studies are integral to the identification of hemorrhagic stroke, determination of the underlying etiology, prevention of hematoma expansion, treatment of acute complications, and treatment of the underlying etiology, if indicated.[ncbi.nlm.nih.gov]
  • OBSERVATION: Detailed work-up for stroke did not reveal any definite etiology. OUTCOME: Weakness gradually improved. Follow-up neuroimaging showed resolution of hemorrhage.[ncbi.nlm.nih.gov]
  • Agranulocytosis is the most serious complication reported with L1 but, to the best of our knowledge, there are no previous reports on hemorrhagic stroke associated with the use of the agent, and hence, the etiology of the stroke which followed agranulocytosis[ncbi.nlm.nih.gov]
  • Rupture of abnormal artery ((in arterialin arterial hypertension) –the most often etiology (60%) ofhypertension) –the most often etiology (60%) of intraceribral hemorrhage 7.[slideshare.net]

Epidemiology

  • Author information 1 Department of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, Beijing, China; Beijing Municipal Key Laboratory of Clinical Epidemiology, Capital Medical University, Beijing, China. 2 Department[ncbi.nlm.nih.gov]
  • Author information 1 Department of Medical Laboratory, Huai'an Third Hospital, Huai'an, 223300, China. 2 Department of Emergency, Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210009, China. 3 Department of Epidemiology[ncbi.nlm.nih.gov]
  • However, as reports have been precarious, the obtaining of epidemiological-clinical data has been affected.[ncbi.nlm.nih.gov]
  • INTRODUCTION: The epidemiology of stroke in sub-Saharan countries is poorly characterized because of lack of population-based studies and national vital statistics systems with complete death registration.[ncbi.nlm.nih.gov]
  • Abstract BACKGROUND: Global stroke epidemiology is changing rapidly.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • This review article summarizes the current knowledge regarding the role and the underlying mechanisms of the NLRP3 inflammasome in the pathophysiological processes of hemorrhagic strokes.[ncbi.nlm.nih.gov]
  • To date, we do not have effective tools to control pathophysiological processes associated with stroke. Thus the microRNAs have to be considered as a very promising target for future stroke therapies.[ncbi.nlm.nih.gov]
  • The pathophysiological mechanisms of these cerebral hemorrhagic diseases have not been fully elucidated, and there are no effective pharmacological and molecular treatments against these diseases.[ncbi.nlm.nih.gov]
  • […] sought to summarize the hemodynamic changes and underline neural vascular mechanism for cerebral blood flow autoregulation in stroke-prone state and after hemorrhagic stroke and hopefully provide more systematic and innovative research interests for the pathophysiology[ncbi.nlm.nih.gov]
  • CONCLUSION: Due to the multiple functions of pericytes in the development of vascular rupture and hemorrhagic stroke pathophysiology, additional drugs and trials targeting pericytes and evaluations of their effectiveness are required in future investigations[ncbi.nlm.nih.gov]

Prevention

  • BACKGROUND: Despite long-standing and worldwide efforts, hemorrhagic stroke remains a critical clinical syndrome that exerts a heavy toll on affected individuals and their families due to the lack of preventive and therapeutic targets.[ncbi.nlm.nih.gov]
  • We found that cilostazol prevented the hemorrhagic transformation induced by focal cerebral ischemia in mice treated with intravenous tissue plasminogen activator or warfarin via protecting endothelial cells and tight junction proteins.[ncbi.nlm.nih.gov]
  • We might recommend a surgical procedure to prevent or stop bleeding or reduce pressure inside the skull. If an aneurysm is the potential cause of the stroke, we can clip it at the base to prevent bleeding before a stroke or to prevent re-bleeding.[utswmed.org]
  • University Yangsan Hospital, Yangsan, Korea. 11 Department of Neurosurgery, Pusan National University College of Medicine, Pusan National University Yangsan Hospital, Yangsan, Korea. 12 Department of Physical and Rehabilitation Medicine, Center for Prevention[ncbi.nlm.nih.gov]
  • Early diagnosis and treatments are very important for patients to prevent the further progression of intracranial hemorrhages. Several patients need a hematoma evacuation and their prognosis is not optimistic.[ncbi.nlm.nih.gov]

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