Presentation
We present a patient with paroxysmal nocturnal hemoglobinuria with diffuse hepatic central vein thrombosis who presented with encephalopathy and recovered from the hepatic manifestations with antihepatic coma measures alone. [ncbi.nlm.nih.gov]
Entire Body System
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Constitutional Symptom
We present a case of a previously healthy 43-year-old Canadian man presenting with constitutional symptoms and right upper quadrant abdominal pain. [ncbi.nlm.nih.gov]
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Turkish
We report the case of a 26-year-old man with a chronic Budd-Chiari syndrome with ascites, caused by a hereditary Protein S deficiency, in a Turkish family with consanguinity. [ncbi.nlm.nih.gov]
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Internal Bleeding
The criteria for ending the therapy were: i) the thrombus was completely dissolved; ii) the thrombus was consistent in two consecutive reviews; and iii) internal bleeding was observed or other complications occurred. [spandidos-publications.com]
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Poor Growth
CASE REPORT A 16-year-old boy was first diagnosed with ulcerative colitis at age 8 years, when he had bloody diarrhea, mouth sores, and poor growth (10 th percentile). [journals.lww.com]
Respiratoric
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Yawning
By Richard Klasco, M.D Photo Credit Ask Well Photo Credit Why Do We Yawn? Reading about yawning makes people yawn. You are probably yawning right now. By Roni Caryn Rabin Latest Search Latest Articles Search Articles 13844 results for sorted by [nytimes.com]
Gastrointestinal
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Abdominal Pain
BACKGROUND/AIMS: Hepatic vein thrombosis is thought to be manifested by ascites, abdominal pain, and hepatomegaly, with a uniformly poor prognosis. [ncbi.nlm.nih.gov]
The syndrome classically presents with abdominal pain, fluid in the abdomen (ascites) and liver enlargement (hepatomegaly).The syndrome can present all of a sudden or gradually. [veindirectory.org]
Liver, Gall & Pancreas
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Hepatomegaly
BACKGROUND/AIMS: Hepatic vein thrombosis is thought to be manifested by ascites, abdominal pain, and hepatomegaly, with a uniformly poor prognosis. [ncbi.nlm.nih.gov]
#4 I'm sure you've figured this out but clinically, you have no hepatomegaly with portal vein thrombosis vs hepatomegaly with hepatic vein thrombosis #5 I did a question on Uworld today on that same concept.....in case you haven't seen the question its [forums.studentdoctor.net]
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Jaundice
We report a 24-year-old Japanese female hospitalized with jaundice and ascites. She exhibited hepatosplenomegaly, severe liver dysfunction, and slight polycythemia with an increase in serum levels of beta-thromboglobin and platelet factor 4. [ncbi.nlm.nih.gov]
Symptoms include: Abdominal swelling or stretching due to fluid in the abdomen Pain in the right upper abdomen Vomiting blood Yellowing of the skin (jaundice) Treatment varies, depending on the cause of the blockage. [nlm.nih.gov]
Symptoms Symptoms include: Abdominal swelling or stretching due to fluid in the abdomen Pain in the right upper abdomen Vomiting blood Yellowing of the skin (jaundice) Exams and Tests One of the signs is swelling of the abdomen from fluid buildup ( ascites [mountsinai.org]
Associated disorders usually include jaundice, haematemesis, leg oedema, oesophageal varices, thrombophlebitis of the inferior vena cava, and portal hypertension. Occurs in an acuta and an intermittent form. More common in males. Bibliography G. [whonamedit.com]
Skin
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Cutaneous Manifestation
This cutaneous manifestation of the anticardiolipin syndrome has not been described before, though its histological appearances resemble those of previously reported cutaneous complications, such as chronic ulceration, livedo reticularis and distal cutaneous [ncbi.nlm.nih.gov]
Workup
Provides all the necessary tools to make a comprehensive diagnostic workup including data from ancillary techniques and molecular findings whenever appropriate. [books.google.com]
As mentioned earlier, another important feature of the laboratory workup is the detection of underlying prothrombotic factors. A thorough workup should be undertaken directed at exploring multiple prothrombotic risk factors. [journals.sagepub.com]
See Workup for more detail. [emedicine.medscape.com]
Microbiology
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Entamoeba Histolytica
Abstract The most common extraintestinal complication of Entamoeba histolytica is amebic liver abscess (ALA). [ncbi.nlm.nih.gov]
Treatment
Both patients had a marked clinical and radiological improvement following the t-PA treatment and remain well over 2 years and 6 years after the treatment. [ncbi.nlm.nih.gov]
Symptoms include: Abdominal swelling or stretching due to fluid in the abdomen Pain in the right upper abdomen Vomiting blood Yellowing of the skin (jaundice) Treatment varies, depending on the cause of the blockage. [nlm.nih.gov]
[…] the treatment was reliable. [spandidos-publications.com]
Prognosis
In asymptomatic patients, prognosis at 3 years seems to be good, and surgical therapy may not be required. [ncbi.nlm.nih.gov]
What is prognosis of patients with hepatic vein thrombosis? If the individual has minimal symptoms and the liver is functioning well, the majority of patients survive for at least 10 years after the diagnosis. [veindirectory.org]
Prognosis Factors associated with a good prognosis include younger age at diagnosis, absence or a small amount of ascites, and a low serum creatinine level. [patient.info]
Etiology
The etiology is often idiopathic but may involve conditions that increase thrombogenic tendencies. Oral contraceptives are known to increase the risk of a number of thrombotic conditions and have been associated with the Budd-Chiari syndrome. [ncbi.nlm.nih.gov]
It has multiple etiologies and a variety of clinical consequences. [unboundmedicine.com]
Though the mechanism was not documented in this patient, the hypercoagulability associated with inflammatory bowel disease may have played an etiologic role (1,2). [journals.lww.com]
Epidemiology
Author information 1 Department of Medicine, McMaster University, Hamilton, Ontario, Canada. 2 Department of Radiology, McMaster University, Hamilton, Ontario, Canada. 3 Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton [ncbi.nlm.nih.gov]
Aims: To investigate the epidemiology, clinical presentation and survival in patients with BCS. [doi.org]
Epidemiology The global prevalence of BCS is unknown but is estimated at 1 in 100,000. [ 3 ] The epidemiology and presentation tend to vary in different parts of the world. [patient.info]
The epidemiology of Budd-Chiari syndrome in France. Dig Liver Dis. 2018 Sep. 50 (9):931-7. [Medline]. Su L, Hu L, Liang P, Wu Y, Sun Q, Gao J. [emedicine.medscape.com]
Pathophysiology
The pathophysiology of this phenomenon involves two major aspects. Oral contraceptives are known to cause a hypercoagulation state as well as a direct effect on the blood vessels. [ncbi.nlm.nih.gov]
/ obliterative hepatocavopathy likely represents recanalized thrombosis, more commonly seen in developing countries Epidemiology Occurs in roughly 0.001% of the population Sites Occlusion may occur anywhere from hepatic venules to inferior vena cava Pathophysiology [pathologyoutlines.com]
Prevention
Recognition of the skin lesion could allow the prevention of major systemic complications. [ncbi.nlm.nih.gov]
Hepatic vein obstruction prevents blood from flowing out of the liver and back to the heart. This blockage can cause liver damage. [nlm.nih.gov]
When the hepatic vein is obstructed, blood flow from the liver to the heart is prevented. This situation is very dangerous as it can lead to the liver being damaged. [buddchiarisyndrome.org]