Presentation
In this report, we present a case of a 50-year-old immunocompetent man with Guillain-Barré syndrome (GBS) associated with an autochthonous hepatitis E virus (HEV) infection. The patient presented with tetraparesis and elevated liver enzymes. [ncbi.nlm.nih.gov]
Entire Body System
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Severe Pain
Abstract We report the case of a Thai male patient with neuralgic amyotrophy, presenting with acute and severe pain in the upper extremities, followed by patchy muscle weakness, associated with hepatitis E virus (HEV) infection. [ncbi.nlm.nih.gov]
Respiratoric
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Pharyngitis
Continuous spectrum of pharyngeal-cervical-brachial variant of Guillain-Barré syndrome. Arch Neurol. 2007;64(10):1519-1523. PubMed Google Scholar Crossref 58. Ito M, Matsuno K, Sakumoto Y, Hirata K, Yuki N. [jamanetwork.com]
Musculoskeletal
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Muscle Weakness
Abstract We report the case of a Thai male patient with neuralgic amyotrophy, presenting with acute and severe pain in the upper extremities, followed by patchy muscle weakness, associated with hepatitis E virus (HEV) infection. [ncbi.nlm.nih.gov]
Neurologic
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Paresthesia
Herein, we report the case of an immunocompetent patient who was admitted to our hospital with paresthesia and weakness in both the upper extremities associated with anicteric-elevated transaminases. [ncbi.nlm.nih.gov]
Patient 2 developed mild GBS, with predominantly sensory symptoms (paresthesia and pain) and mild paresis (limbs and mild dysarthria) without ataxia or areflexia; he received no immunomodulatory treatment. [jamanetwork.com]
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Stroke
KEYWORDS: Epidemiology; Hepatitis E virus (HEV); Neuralgic amyotrophy; Seizure; Stroke [ncbi.nlm.nih.gov]
Workup
[…] acute hepatitis when baseline workup is inconclusive. [ncbi.nlm.nih.gov]
Further studies are required to guide neurologists in their workup of underlying triggers of GBS. [jamanetwork.com]
X-Ray
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Pericardial Effusion
Despite intensive care the patient died 39 days after admission due to pericardial effusion that was related to acute liver failure. [ncbi.nlm.nih.gov]
Treatment
In the context of HEV-associated cutaneous T cell lymphoproliferative disorders, antiviral treatment could be considered a first-line treatment instead of chemotherapy. [ncbi.nlm.nih.gov]
Prognosis
Although the role of ribavirin remains to be fully determined, early diagnosis and treatment may result in an improved prognosis, thereby minimizing neurological sequelae. [Indexed for MEDLINE] Free full text [ncbi.nlm.nih.gov]
Patients with underlying chronic liver disease have a poor prognosis with a mortality of 27% 14 ; their cause of death is usually (sub)acute liver failure. [pn.bmj.com]
Etiology
Author information 1 Centre de Néphrologie et Transplantation Rénale, Hôpital Conception, Assistance Publique des Hôpitaux de Marseille, Aix-Marseille Université, Marseille, France. [email protected] Abstract Hepatitis E virus (HEV), the main etiologic agent [ncbi.nlm.nih.gov]
Bradley DW, Andjaparidze AG, Cook EH, McCaustland K, Balayan M, Stetler H, Velazques O, Robertson B, Humphrey C, Kane M, Weisfuse I (1988) Etiologic agent of enterically transmitted non-A, non-B hepatitis. [link.springer.com]
Epidemiology
Author information 1 Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany. 2 Institute of Clinical Microbiology and Hygiene, University Medical Center Regensburg, Regensburg, Germany. 3 Department of Epidemiology and [ncbi.nlm.nih.gov]
Project summary The epidemiology of HEV infections in Belgium is not well described, and the zoonotic aspects were only recently recognised. In this project, we examine the epidemiology of HEV in Belgium. [sciensano.be]
Pathophysiology
Objective: This review aimed at summarizing the role played by HEV on the exacerbation of chronic hepatitis B and the pathophysiology of acute-on-chronic liver failure. [amhsr.org]
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Hepatitis E virus (HEV) causes an acute, usually self-limited infection. [mayomedicallaboratories.com]
Van Alfen N (2011) Clinical and pathophysiological concepts of neuralgic amyotrophy. Nat Rev Neurol 7:315–322 CrossRef PubMed 3. [springermedizin.de]
Prevention
Control and Prevention, Chinese Center for Disease Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing, China. [ncbi.nlm.nih.gov]