Edit concept Question Editor Create issue ticket

Hepatitis G

GBV


Presentation

  • In mononuclear cell samples (n 15) 100% presented the genomic chain of HCV and 60% presented that of HGV (p 0.05). Antigenomic chains were detected in 13 and 33%, respectively (ns).[ncbi.nlm.nih.gov]
Asymptomatic
  • Hepatitis G virus antibody was more frequent in patients with chronic liver disease (36.4%-43.9%) than in asymptomatic persons (23.1%).[ncbi.nlm.nih.gov]
  • Case Definition (*) Clinical description Persons with chronic Hepatitis B virus (HBV) infection may be asymptomatic.[cdc.gov]
Fever
  • The physical examination presents fever, pallor whereas bleeding, hepatomegaly, Splenomegaly and bruising were absent, abdominal ultrasonography confirmed the absence of hepatomegaly, Splenomegaly and lymphodenopathy.[ncbi.nlm.nih.gov]
  • At a Glance Hepatitis G virus, more properly known as GB virus type C (GBV-C), is a flavivirus; the same class of viruses as hepatitis C and yellow fever virus.[cancertherapyadvisor.com]
Malaise
  • Hepatitis may occur with limited or no symptoms, but often leads to yellow discoloration of the skin, mucus membranes, and conjunctivae, poor appetite and malaise.[disabled-world.com]
  • ., anorexia, nausea, malaise, vomiting, dark urine, clay colored or light stools, and abdominal pain). Appropriate diagnostic testing of such patients is crucial to ensure complete case ascertainment.[cdc.gov]
Loss of Appetite
  • Others may have; Diarrhea Stomach pain Loss of appetite Nausea and vomiting Jaundice, yellowing of skin and eyes Dark-colored urine and pale bowel movements Statistics: Hepatitis Viral hepatitis is the most common cause of hepatitis worldwide.[disabled-world.com]
  • For those who do develop symptoms of viral hepatitis, the most common are flu- like symptoms including: Loss of appetite Nausea Vomiting Fever Weakness Tiredness Aching in the abdomen Less common symptoms include: Dark urine Light-colored stools Fever[medicinenet.com]
  • DISEASE-SPECIFIC SURVEILLANCE GUIDELINES Acute Hepatitis A Case Definition (*) Clinical criteria An acute illness with discrete onset of symptoms (e.g. fatigue, abdominal pain, loss of appetite, intermittent nausea, vomiting), and jaundice or elevated[cdc.gov]
Jaundice
  • History In 1964 a surgeon whose initials are G.B. contracted a hepatitis with jaundice. His serum was saved frozen by Isa K. Mushahwar at Abbott laboratories near Chicago. In 1995 the serum produced hepatitis in tamarins.[meddean.luc.edu]
  • Typically, these patients do not have jaundice until the liver damage is far advanced. Therefore, these patients can remain undiagnosed for years to decades.[medicinenet.com]
  • None of the 10 patients had jaundice.[nejm.org]
  • No significant difference was observed between the age group which had acute self-limited disease and a serum aspartate aminotransferase (AST) elevation of atleast five fold or clinical jaundice or both.[iisc.ernet.in]
Dermatitis
  • Church, CysLT1 antagonists in the treatment of atopic dermatitis and urticaria, Clinical & Experimental Allergy Reviews, 1, 3, (305-308), (2002). M. L. Moy and J. M.[doi.org]
Urticaria
  • Church, CysLT1 antagonists in the treatment of atopic dermatitis and urticaria, Clinical & Experimental Allergy Reviews, 1, 3, (305-308), (2002). M. L. Moy and J. M.[doi.org]
Cesarean Section
  • There may be intranatal infection of a baby at delivery by the maternal passage, as confirmed by the data on a significant reduction in the infection rates of neonates after cesarean section of their mothers[ 55 ].[dx.doi.org]

Workup

Nephrolithiasis
  • […] novo MPGN type 1 associated with HGV infection in a young male renal transplant recipient who manifested glomerulonephritis (GN) with proteinuria 7 years after transplant, and whose original disease was chronic obstructive pyelonephritis secondary to nephrolithiasis[ncbi.nlm.nih.gov]
HLA-DR8
  • HLA typing in GBV-C-infected patients with hemophilia showed that 22% of the RNA-positive patients and 72% of the anti-E2-positive patients had HLA DQ7, HLA DR15 and HLA DR8.[dx.doi.org]

Treatment

  • ., subjects who were currently seeking treatment for an STD) compared with the group who never had received treatment for an STD.[ncbi.nlm.nih.gov]
  • Treatment There is no specific treatment for any form of acute hepatitis. Patients should rest in bed as needed, avoid alcohol, and be sure to eat a balanced diet.[web.archive.org]

Prognosis

  • HGV or GBV-C has been ascertained to influence course and prognosis in the HIV-infected patient.[ncbi.nlm.nih.gov]
  • Prognosis What little is known about the course of hepatitis G suggests that illness is mild and does not last long. When more patients have been followed up after the acute phase, it will become clear whether HGV can cause severe liver damage.[web.archive.org]

Etiology

  • The role of this novel virus in the pathogenesis of chronic liver injury of unknown etiology appears insignificant in our geographic area.[ncbi.nlm.nih.gov]

Epidemiology

  • A review of literature was performed in 2009 to summarize scientific reports on epidemiology and pathogenesis of the HGV infection and its exposure through hemodialysis.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Prevention

  • Prevention Since hepatitis G is a blood-borne infection, prevention relies on avoiding any possible contact with contaminated blood. Drug users should not share needles, syringes, or other equipment.[web.archive.org]
  • Ribavirin Combination of interferon and ribavirin Treatment Prevention: Absence of vaccine or any other specific prevention method. Non-specific prevention is used. Prevent sharing of personal items that might contain contaminated blood. Prevention[authorstream.com]
  • Assessing missed opportunities for prevention.[cdc.gov]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!