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Hepatobiliary Disorder

Liver and Biliary System Disorders


Presentation

  • […] and Caroli’s disease presenting in older children.[tropicalgastro.com]
  • “The relationship of PBC with UC [ulcerative colitis] remains obscure as there are few reported cases regarding the combined presentation of these diseases.[mdedge.com]
  • Aside from these topics, the volume presents basic research on hepatic transport mechanisms, intrahepatic cholestasis and gall-stone disease, which serves as a background for the topics more specifically concerning the assessment of liver function.[books.google.de]
  • Careful history taking and examination are required to establish the cause and, if a hepatobiliary disorder is present, to determine whether it is pre-existing, coincidental or related to the pregnancy.[medicinetoday.com.au]
  • […] storage REGENERATION of its own tissue The Biliary Tract Hepatic ducts Cystic ducts Common Bile Ducts Ampulla of Vater and Sphincter of Oddi Gallbladder Exocrine pancreas Assessment MANY SXS RELATED TO THE DIGESTIVE PROCESS History - CC and Hx of the present[unf.edu]
Fatigue
  • (leads to cirrhosis) •Anorexia and wt. loss •Early morning nausea and vomiting (with blood) •Flatulence and changes in bowel habits •Emaciation •fatigue •Jaundice •Abdominal pain and tenderness •Ascites •Peripheral edema •Dry skin and rashes •Petechiae[quizlet.com]
Rigor
  • I found the peer review process was rigorous, and helped to improve the overall quality of my manuscript without being too tedious.[elynsgroup.com]
  • To answer the question, rigorously tested algorithms defining the usefulness and cost-effectiveness of many diagnostic tests must be performed.[journals.lww.com]
HELLP Syndrome
  • Severe pre-eclampsia with hepatic involvement, HELLP syndrome and acute fatty liver of pregnancy are indications for delivery.[medicinetoday.com.au]
Respiratory Distress
  • distress discomfort compression of abd viscera, blood vessels diagnostic purposes complications replace albumin Hepatic Encephalopathy We will look at this condition via our Critical Thinking Text![unf.edu]
Tachypnea
  • […] consciousness Alcohol Withdrawl Syndrome Deprivation of his/her normal amount of Etoh tremulousness, anxiety (morning drink) anorexic, insomnia, irritability, HA, few hours to 36 hrs p last intake of etoh signs and symptoms tachycardia, hypertension, tachypnea[unf.edu]
Deepening of Voice
  • […] of voice •Increase virilism (changes that make a male body different than female) •Hematologic disorders -Anemia, thrombocytopenia, coagulation defects, leukopenia •Endocrine disorders -Fluid retention, hypokalemia, disordered sexual functions •Skin[quizlet.com]
Abdominal Pain
  • (leads to cirrhosis) •Anorexia and wt. loss •Early morning nausea and vomiting (with blood) •Flatulence and changes in bowel habits •Emaciation •fatigue •Jaundice •Abdominal pain and tenderness •Ascites •Peripheral edema •Dry skin and rashes •Petechiae[quizlet.com]
  • Abdominal pain is a common symptom seen in gallbladder cancer - gallbladder (green) behind liver (red).[news-medical.net]
  • Evaluation of acute abdominal pain in adults. Am Fam Physician [online] 2008 Apr 1, 77(7):971-8 [viewed 15 November 2015] Available from: 2. MACALUSO CR, MCNAMARA RM.[clinicalsenseapp.com]
  • Gallstones Stones can be cholesterol(75%) or pigmented black, brown These are cholesterol stones Pancreatitis Caused by activation of its own enzymes which cause autodigestion of the pancreas sudden severe upper abdominal pain with n/v, and elevation[unf.edu]
Failure to Thrive
  • Common clinical presentations were jaundice in 32 (71%), dark urine in 19 (42%), fever in 13 (29%), failure to thrive in 7 (16%), splenomegaly in 21 (47%) and hepatomegaly in 32 (71%).[tropicalgastro.com]
  • Among the gastrointestinal disorders, the algorithms should be established for 7) congenital diarrheas, 8) pancreatitis and pancreatic insufficiency, 9) inflammatory intestinal disorders, 10) chronic diarrhea, 11) failure to thrive, 12) GI bleeding, and[journals.lww.com]
Hepatosplenomegaly
  • Also patients with Caroli’s disease presented without jaundice and predominantly only as hepatosplenomegaly. Though elevated liver transaminanses are seen in most children, AST remains normal in Caroli’s disease (p 0.03).[tropicalgastro.com]
Skin Discoloration
  • discolor Interventions Discuss these with me![unf.edu]
Flushing
  • Alcohol Withdrawl Syndrome Deprivation of his/her normal amount of Etoh tremulousness, anxiety (morning drink) anorexic, insomnia, irritability, HA, few hours to 36 hrs p last intake of etoh signs and symptoms tachycardia, hypertension, tachypnea, facial flushing[unf.edu]
Dry Skin
  • (leads to cirrhosis) •Anorexia and wt. loss •Early morning nausea and vomiting (with blood) •Flatulence and changes in bowel habits •Emaciation •fatigue •Jaundice •Abdominal pain and tenderness •Ascites •Peripheral edema •Dry skin and rashes •Petechiae[quizlet.com]
Hirsutism
  • […] shoulders) •Hepatomegaly (enlarged liver) •Protruding umbilicus •Dilated abdominal veins Cirrhosis damage, Males (increase estrogen) •Gynecomastia (boobs) •Impotence •Fall of body hair •Atrophy of testicles Cirrhosis damage, Females(increase androgren) •Hirsutism[quizlet.com]
Denial
  • Denial, in this case, can be deadly. Cancer Sometimes patients have cancer in the different parts of the body and it spreads to the liver.[marham.pk]
Tremulousness
  • […] evaluation Alcohol abuse contribute to and worsen the various disorders acute intoxication decrease in inhibitions ataxia and dysarthria argumentativeness loss of consciousness Alcohol Withdrawl Syndrome Deprivation of his/her normal amount of Etoh tremulousness[unf.edu]
Dark Urine
  • Common clinical presentations were jaundice in 32 (71%), dark urine in 19 (42%), fever in 13 (29%), failure to thrive in 7 (16%), splenomegaly in 21 (47%) and hepatomegaly in 32 (71%).[tropicalgastro.com]
  • SIGNS AND SYMPTOMS  Many are asymptomatic  Nausea, vomiting, anorexia, RUQ abdominal pain, liver enlargement  Malaise, fever  Sclera become yellow (icteric)  Jaundice, dark urine, clay-colored stools  Elevated ALT, AST, bilirubin levels 64 65.[slideshare.net]

Workup

  • The Development of Diagnostic Guidelines and Algorithms The availability of genetic testing has altered the diagnostic workup for many disorders.[journals.lww.com]

Treatment

  • Keep in mind that treatment for the ailment is your first obligation towards you. So whenever you came to know about ailment start the treatment to save the health and life, the true blessing of Almighty.[marham.pk]
  • Diagnosis and Treatment We typically diagnose hepatobiliary disorders by using several tests: Blood tests measure liver function and blood clotting. Liver biopsies involve removing a small piece of the tumor to test is in the lab.[mountsinai.org]
  • Our centre is a tertiary referral centre and patients from Western India are referred for specialized treatment.[tropicalgastro.com]

Prognosis

  • Esophageal varices Common in cirrhosis difficult to control medical tx - endoscopic injection sclerotherapy or ligation insertion of a Sengstaken-Blakemore tube transjugular intrahepatic portasystemic shunt (TIPS) prognosis - third leading cause of death[unf.edu]
  • Kageoka et al evaluated the long-term prognosis of 262 patients following endoscopic sphincterotomy for choledocholithiasis and the need for cholecystectomy post endoscopic sphincterotomy. [23] Patients were divided into four groups according to previous[emedicine.medscape.com]
  • The prognosis of KD can be considered from the aspects of clinical response to IVIG treatment and ongoing complications of the coronary arteries.[bmcpediatr.biomedcentral.com]

Etiology

  • Clinical and biochemical factors of chronic hepatobiliary disorders and their association with various etiologies of CLD were analyzed.[tropicalgastro.com]
  • Another study reported that the gastrointestinal tract in KD is the primary site for the entry of etiologic agents that predispose to KD [ 14 , 17 ].[bmcpediatr.biomedcentral.com]
  • Depending on the etiology of the cholangitis and the comorbid status of the patient, biliary drainage is established by endoscopic retrograde cholangiopancreatography (ERCP)–guided sphincterotomy and stone extraction or biliary stent placement.[emedicine.medscape.com]
  • .  Etiology  Infection is by fecal-oral route.  Risk Factors  Improper hand washing and food preparation  Day care center attendance (children)  Recent use of antibiotics 27 28.[slideshare.net]

Epidemiology

  • Masoud Mohammadnezhad, Fiji National University It is with great pleasure that I provide this letter of support for the Journal of Epidemiology and Preventative Medicine (JEPM), following my recent experience as a publishing author for the journal.[elynsgroup.com]
  • The epidemiology of gallstone disease. Pp. 1-26 in S. Cohen and R.D. Soloway, eds. Contemporary Issues in Gastroenterology. Churchill Livingstone, New York. Terris, M. 1967. Epidemiology of cirrhosis of the liver: national mortality data. Am. J.[nap.edu]
  • Nationwide epidemiological survey of autoimmune pancreatitis in Japan in 2011 . Pancreas 44 , 535–539 (2015). 11. Kanno, A. et al . Nationwide epidemiological survey of autoimmune pancreatitis in Japan . Pancreas 41 , 835–839 (2012). 12.[nature.com]
  • Epidemiology of liver disease in cystic fibrosis: a longitudinal study. J Hepatol. 2004; 41 (6): 920-5[ DOI ][ PubMed ] 11. Colombo C, Battezzati PM, Crosignani A, Morabito A, Costantini D, Padoan R, et al.[hepatmon.com]
Sex distribution
Age distribution

Pathophysiology

  • Prevention and reduction of risk factors Education of the public regarding etoh abuse and its relationship to cirrhosis work/leisure exposure to hepatotoxins assess medication regimens correct handling of sharps/body fluids CIRRHOSIS IS IRREVERSIBLE Pathophysiology[unf.edu]
  • It is also the long-term expectation that such gene discoveries will provide us with better insight into pathophysiology of these disorders, and therefore provide prospects for novel therapies.[journals.lww.com]
  • Published on Nov 25, 2014 lecture for pathophysiology 1. THE GASTROINTESTI NAL AND HEPATOBILIARY SYSTEMS Barry University NUR 313 2.[slideshare.net]

Prevention

  • There has been conflicting evidence to both support and refute the rationale that colectomy will prevent the development of, or arrest, existing disease of the liver.[ncbi.nlm.nih.gov]
  • Biliary atresia can prevent bile from being able to drain from the liver into the intestine. It stems from abnormal development of the biliary system.[mountsinai.org]
  • Masoud Mohammadnezhad, Fiji National University It is with great pleasure that I provide this letter of support for the Journal of Epidemiology and Preventative Medicine (JEPM), following my recent experience as a publishing author for the journal.[elynsgroup.com]
  • […] flow Causes Four major pathological classifications alcoholic - postnecrotic - biliary - cardiac excessive etoh consumption viral hepatitis hepatic injury from hepatotoxins prolonged extrahepatic biliary obstruction severe right sided heart failure Prevention[unf.edu]

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