CONCLUSION: Age, ingested amount, delayed presentation, and reason for exposure were likely to be determinants of the severity of GlySH exposure. [ncbi.nlm.nih.gov]

However, due to the poor outcomes in patients who present with severe toxicity it may have a role in addition to standard intensive care support. More research should be conducted. [cochrane.org]

• Hodgkin Lymphoma

  Diseases ranging from autism, Alzheimer’s, and diabetes to pancreatic cancer, thyroid cancer, non-Hodgkin’s lymphoma, Parkinson’s disease and—wait for it—the ongoing collapse of bee colonies. [outsideonline.com]

  The VA also notes that non-Hodgkin’s lymphoma is also associated with exposure to the defoliant. Herbicides are also suspected as causes of prostate cancer, cancers of the lungs and bronchial tubes, and cancers of the larynx and trachea. [livestrong.com]

  lymphoma. 5 According to two Swedish studies, phenoxy herbicides also show an increased risk of soft-tissue sarcomas. [sustainablebabysteps.com]

  Researchers have observed apparent links between exposure to 2,4-D and non-Hodgkin's lymphoma (a blood cancer) and sarcoma (a soft-tissue cancer). [nrdc.org]

  The studies found glyphosate in farmworkers’ blood and urine, chromosomal damage in cells, increased risks of non-Hodgkin lymphoma in some people exposed, and tumor formation in some animal studies. [news.nationalgeographic.com]

• Fatigue

  vomiting, skin/airway/mucous membrane irritation, renal dysfunction, coma O, R, D Coumarins (rodenticide) Brodifacoum, warfarin, pindone Echymoses, epistaxis, excessive bleeding, haematuria, prolonged prothrombin time, intracranial bleed, anaemia, fatigue [who.int]

  Headache, fatigue, soreness in joints, irritation of nose and throat. Yes. Fever, intense thirst, vomiting, muscle twitches, pinpoint pupils, unconsciousness. Yes. [articles.extension.org]

  Victims may also have symptoms of anemia, including fatigue. If poisoning is severe, the victim may progress to shock and death. Zinc phosphide Poisonings by ingested zinc phosphide are extremely difficult to manage. [extension.missouri.edu]

• Abdominal Pain

  pain, fever, tremor O, R, D Pyrethrins, Pyrethroids Allethrin, cyfluthrin, permethrin Allergic reactions, anaphylaxis, dermatitis, paresthesias, wheezing, seizures, coma, pulmonary oedema, diarrhoea, abdominal pain R, D Strychnine (rodenticide) Strychnine [who.int]

  Vomiting, abdominal pain, diarrhea, and, occasionally, gastrointestinal hemorrhage were early effects. [ncbi.nlm.nih.gov]

  The next signs of illness following ingestion are gastrointestinal (digestive tract) symptoms, such as nausea, vomiting, abdominal pain, and diarrhea (which may become bloody). [emergency.cdc.gov]

  Internal Exposure: Weakness, shaking, vomiting, cough, difficulty in breathing, intense thirst External Exposure: Irritates eyes, nose, and throat Chronic Exposure: Pain in eyes and nose; nosebleeds; abdominal pain Chemical Family: Metal Phosphides [articles.extension.org]

  Following ingestion, vomiting, abdominal pain, diarrhoea and, occasionally, gastrointestinal haemorrhage are early effects. [link.springer.com]

• Hypotension

  After 10 h of ingestion patient had sudden respiratory distress along with hypotension and was hence intubated and ventilated. [ijccm.org]

  Three patients died after manifesting profound hypotension and/or coma following alachlor ingestion. CONCLUSION: Alachlor and butachlor poisonings are usually of low toxicity. [ncbi.nlm.nih.gov]

  The toxicity in humans is mucosal and gastrointestinal irritation, hypotension, metabolic acidosis, pulmonary insufficiency, and oliguria. [mjdrdypu.org]

  Many of the commonly used agricultural herbicides can produce symptoms ranging from skin irritation to hypotension, liver and kidney damage, and coma or convulsions. Estimated fatal doses may be as small as 1 to 10 g. [medical-dictionary.thefreedictionary.com]

• Miosis

  Neurotoxic features included coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations, convulsions, fasciculation, and paralysis. [ncbi.nlm.nih.gov]

  […] cardiac arrhythmias, acidosis O, R, D Organophosphates (insecticides) Malathion, parathion, dichlorvos, chlorpyrifos Headache, dizziness, bradycardia, weakness, anxiety, excessive sweating, fasciculations, vomiting, diarrhoea, abdominal cramps, dyspnea, miosis [who.int]

  Coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations, convulsions, fasciculation and paralysis may then ensue. [link.springer.com]

• Muscle Weakness

  Myopathic symptoms including limb muscle weakness, loss of tendon reflexes, and myotonia were observed and increased creatine kinase activity was noted in some cases. [ncbi.nlm.nih.gov]

  Pain may be present, as well as muscle weakness and sensitivity to touch. Acute peripheral neuropathy occurs within a few weeks of being exposed. The VA cites peripheral neuropathy as another symptom of exposure to Agent Orange. [livestrong.com]

  Myopathic symptoms including limb muscle weakness, loss of tendon reflexes, myotonia and increased creatine kinase activity have been observed. [link.springer.com]

  weakness Pulmonary edema (fluid in the lungs) Respiratory (breathing) failure, possibly leading to death Seizures Showing these signs and symptoms does not necessarily mean that a person has been exposed to paraquat. [emergency.cdc.gov]

  Moderate Poisoning or Early Symptoms of Acute Poisoning nausea, diarrhea, excessive saliva, stomach cramps, excessive perspiration, trembling, no muscle coordination, muscle twitches, extreme weakness, mental confusion, blurred vision, difficulty in breathing [articles.extension.org]

• Polyuria

  […] weakness, muscle spasm, coma, acidosis, hypotension, ataxia, hypertonia, seizures, dermal irritation, headache, confusion, acidosis, tachycardia O, D Calciferol (rodenticide) Cholecalciferol, ergocalciferol Fatigue, anorexia, weakness, headache, nausea, polyuria [who.int]

• Renal Injury

  injury, hypercalcemia O Chloralose Chloralose Vomiting, vertigo, tremor, myoclonus, fasciculations, confusion, convulsions O Copper compounds (fungicide) Copper acetate, copper oleate Abdominal pain, vomiting, skin/airway/mucous membrane irritation, [who.int]

• Irritability

  irritation of the nose and throat. [articles.extension.org]

  headache, restlessness, ataxia, confusion, seizures, urticaria O, D Dipyridil (herbicide) Paraquat, diquat Mucous membrane and airway irritation, abdominal pain, diarrhoea, vomiting, gastrointestinal bleeding, pulmonary oedema, dermatitis, renal and [who.int]

  Such effects include asthma, skin irritation and eye and nose irritation. Not all people develop allergies; however, certain people seem to be more sensitive than others to chemical irritants. [extension.missouri.edu]

  Many of the commonly used agricultural herbicides can produce symptoms ranging from skin irritation to hypotension, liver and kidney damage, and coma or convulsions. Estimated fatal doses may be as small as 1 to 10 g. [medical-dictionary.thefreedictionary.com]

  It can cause a wide range of clinical manifestations in human beings like skin and throat irritation to hypotension, oliguria and death. [ncbi.nlm.nih.gov]

• Peripheral Neuropathy

  Acute peripheral neuropathy occurs within a few weeks of being exposed. The VA cites peripheral neuropathy as another symptom of exposure to Agent Orange. [livestrong.com]

  Substantial dermal exposure has been reported to cause mild gastrointestinal irritation after a latent period followed by progressive mixed sensory-motor peripheral neuropathy. [ncbi.nlm.nih.gov]

  Neuropathy following exposure to a dimethylamine salt of 2,4-D. Arch Intern Med 1963; 111: 351–2 PubMed CrossRef Google Scholar 52. Goldstein NP, Jones PH, Brown JR. Peripheral neuropathy after exposure to an ester of dichlorophenoxyacetic acid. [link.springer.com]

• Nystagmus

  Neurotoxic features included coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations, convulsions, fasciculation, and paralysis. [ncbi.nlm.nih.gov]

  Coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations, convulsions, fasciculation and paralysis may then ensue. [link.springer.com]

• Hyperreflexia

  Neurotoxic features included coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations, convulsions, fasciculation, and paralysis. [ncbi.nlm.nih.gov]

  Coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations, convulsions, fasciculation and paralysis may then ensue. [link.springer.com]

• Paresthesia

  renal dysfunction O, R, D Metal phosphides(rodenticide, fumigant) Zinc-, aluminium-, magnesium- phosphide Abdominal pain, diarrhoea, acidosis, shock, jaundice, paresthesias, ataxia, tremors, coma, pulmonary oedema, tetany, dermal irritation O, R, D [who.int]

See Workup. Treatment begins with decontamination. Airway control and oxygenation are paramount. The mainstays of pharmacological therapy include atropine, pralidoxime (2-PAM), and benzodiazepines (eg, diazepam). [emedicine.medscape.com]

In recent times, the efficacy of intravenous lipid emulsion (ILE) administration for the treatment of acute poisoning caused by Gly- SH has been investigated. [ncbi.nlm.nih.gov]

This review looked for studies where this treatment had been given to poisoned patients. No studies of sufficient quality were identified and therefore routine use of this approach to treatment cannot be recommended. [cochrane.org]

This question featured in : Mercury poisoning treatment Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [practo.com]

More information and ongoing updates as to treatment and prognosis are available at www.auburn.edu/oaks. [wireeagle.auburn.edu]

Early renal replacement therapy may improve prognosis, but there is no evidence to support this and requires identification of those at risk. [5] Intravenous fat emulsion (IFE) has been used in the management of severe local anesthetic toxicity, calcium [mjdrdypu.org]

Patients developing acute kidney injury, hyperkalemia, pulmonary edema and metabolic acidosis are more likely to die. [5] Early renal replacement therapy may improve prognosis but there is no evidence to support this and requires identification of those [ijccm.org]

We evaluated the effect of the paraquat ban on the epidemiology and mortality of herbicide-induced poisoning. [ncbi.nlm.nih.gov]

Dozens of epidemiological, animal, and laboratory studies have shown a link between 2,4-D and thyroid disorders. "That's really important when we're thinking about development," says Kristi Pullen, a staff scientist in NRDC's Health program. [nrdc.org]

I -PA-96) reviewed the 2,4-D epidemiology and toxicology data packages and concluded that after 50 years of extensive use, "The phenoxy herbicides are low in toxicity to humans and animals. [fairlington.org]

Although most patients rapidly become symptomatic, the onset and severity of symptoms depend on the specific compound, amount, route of exposure, and rate of metabolic degradation. [5] Epidemiology Frequency United States In 2016, the American Association [emedicine.medscape.com]

Review of 2,4-dichlorophenoxyacetic acid (2,4-D) epidemiology and toxicology. Crit Rev Toxicol 2002; 32: 233–57 PubMed CrossRef Google Scholar 61. Hoar SK, Blair A, Holmes FF, et al. [link.springer.com]

These have included difficulties in executive functions, psychomotor speed, verbal, memory, attention, processing speed, visual-spatial functioning, and coordination. [4] Pathophysiology The primary mechanism of action of organophosphate pesticides is [emedicine.medscape.com]

[email protected] Centers for Disease Control and Prevention (CDC), National Institute for Occupational Safety and Health (NIOSH), Pocket Guide to Chemical Hazards. [emergency.cdc.gov]

A water-based layer prevents oily substances from being absorbed and a fatty layer of the skin prevents water soluble substances from being absorbed. [theguardian.com]

Cut Stump Treatment Prevents regrowth of trees following mechanical control. Crops See full label for details. [dowagro.com]

To prevent poisoning it is important to use and store products exactly as their labels say. Keep dangerous products where children can't get to them. Treatment for poisoning depends on the type of poison. [icdlist.com]

You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. Take the container with you to the hospital, if possible. [medlineplus.gov]