Presentation
A 9-year-old boy presented with sudden onset of nausea, vomiting and unsteady gait after a bread-eating game, which possibly caused neck hyperextension. [ncbi.nlm.nih.gov]
Updated content presents the latest coding information so you can practice with the most current information available. [books.google.com]
[…] ofLMS can be subtle, with non-specic symptoms suchas vomiting in the absence of altered level of conscious-ness, as in the present patient. [docslide.com.br]
The time taken from addition of thrombin to citrated plasma, to fibrin clot formation is recorded as the thrombin time and presented in seconds. [medirox.se]
Entire Body System
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Fishing
2014: Climate change vulnerability of native and alien freshwater fishes of California: a systematic assessment approach. Freshwater fishes are highly vulnerable to human-caused climate change. [wwe.geoscience.net]
X-linked syndromic 7 Microcephaly micropenis convulsions Craniorachischisis Verloes Bourguignon syndrome Spondyloepimetaphyseal dysplasia Strudwick type Hyperprolinemia type 2 Ethylmalonic encephalopathy Bilateral perisylvian polymicrogyria Oguchi disease Fish-eye [checkrare.com]
Hematological
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Easy Bruising
Factor X deficiency commonly causes nosebleeds, easy bruising, bleeding under the skin, bleeding of the gums, blood in the urine (hematuria), and prolonged or excessive bleeding following surgery or trauma. [icdlist.com]
More than half of the probands had experienced one or more undue bleeding episode, easy bruising being by far the most common. [journals.lww.com]
Bleeding manifestations are nonspecific and include nose bleeds, easy bruising, heavy menstruation, muscle and joint hemorrhage, postoperative bleeding, bleeding during or after childbirth and delayed wound healing. [clinlabnavigator.com]
At the time of diagnosis, most adults have noticed increased bleeding and easy bruising for several weeks, or even months. In women, increased menstrual blood flow is a major sign. Many adults have only mild thrombocytopenia. [slideshare.net]
Easy bruising, nose and mouth bleeds, and soft tissue bleeds are also common. Joint bleeding is relatively uncommon. Women with afibinogenemia have an increased risk of spontaneous abortion. [myneighborhoodprimarycare.org]
Respiratoric
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Hoarseness
[…] disease Ataxia-oculomotor apraxia type 1 49,XXXXX syndrome Bardet-Biedl syndrome Radial hypoplasia, triphalangeal thumbs and hypospadias Limb-girdle muscular dystrophy Intestinal atresia multiple Autosomal recessive Charcot-Marie-Tooth disease with hoarseness [checkrare.com]
Gastrointestinal
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Nausea
A 9-year-old boy presented with sudden onset of nausea, vomiting and unsteady gait after a bread-eating game, which possibly caused neck hyperextension. [ncbi.nlm.nih.gov]
Case reportA 9-year-old boy was admitted to our hospital withvertigo and nausea. The day before admission, he hadexperienced sudden onset of nausea, vomiting and head-ache after a bread-eating game that had possiblyresulted in neck hyperextension. [docslide.com.br]
Side effects Nausea, vomiting, allergic reactions (fever, urticaria). Interaction Compatible with a concentrate of factor VIII (possibly combined assignment for inducing immunotolerance in patients with an inhibitory form of hemophilia). [drdoping.com]
The most common adverse reactions that have been reported after RiaSTAP therapy are allergic reactions and generalized reactions such as chills, fever, headache, as well as nausea and vomiting. [aetna.com]
Skin
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Skin Bleeding
Factor X deficiency commonly causes nosebleeds, easy bruising, bleeding under the skin, bleeding of the gums, blood in the urine (hematuria), and prolonged or excessive bleeding following surgery or trauma. [icdlist.com]
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Delayed Wound Healing
Bleeding manifestations are nonspecific and include nose bleeds, easy bruising, heavy menstruation, muscle and joint hemorrhage, postoperative bleeding, bleeding during or after childbirth and delayed wound healing. [clinlabnavigator.com]
Eyes
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Diplopia
Although originally described as secondary toocclusion of the PICA, the vertebral artery is morevertigo, nausea, vomiting, gait and ipsilateral limbataxia, diplopia, ipsilateral Horners syndrome, ipsilat-eral facial anesthesia, contralateral hemianesthesia [docslide.com.br]
Psychiatrical
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Suggestibility
Neurological examination revealed hemisensory loss of pain and temperature sensation in the right trunk and limbs along with left Horner's syndrome, suggesting lateral medullary syndrome (LMS). [ncbi.nlm.nih.gov]
A special focus has been placed on noninvasive imaging techniques, normative blood pressure standards, suggested approaches to pediatric hypertension, detection and management of lipid abnormalities as recommended by the Expert Panel, pediatric arrhythmias [books.google.com]
Neurological examination revealed hemisensory loss of pain and temperature sensation in the righttrunk and limbs along with left Horners syndrome, suggesting lateral medullary syndrome (LMS). [docslide.com.br]
Bonna also suggested that homocysteine could be a marker, but not a cause, of vascular disease. [thrombosisjournal.biomedcentral.com]
Neurologic
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Hemianesthesia
Although originally described as secondary toocclusion of the PICA, the vertebral artery is morevertigo, nausea, vomiting, gait and ipsilateral limbataxia, diplopia, ipsilateral Horners syndrome, ipsilat-eral facial anesthesia, contralateral hemianesthesia [docslide.com.br]
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Truncal Ataxia
Due to truncal ataxia, he had dicultysitting upright without support. [docslide.com.br]
Workup
However, this can be useful adjunct in the diagnostic workup of certain other disorders as well. We have described a case of dysfibrinogenemia where platelet aggregation study was used to characterize the defect. [ehj.eg.net]
Serum
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Prothrombin Time Prolonged
Symptoms include: • umbilical cord bleeding at birth • nose bleeds • abnormal menstrual bleeding • abnormal bleeding after delivery • bleeding after trauma • bleeding after surgery • easy bruising Signs and Tests: • prolonged prothrombin time • prolonged [slideshare.net]
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Decreased Platelet Count
Decreased platelet count is seen in - Viral infection - Idiopathic - Aplastic anaemia 6 7. II. COAGULATION : Primary hemostasis is platelet plug formation. Secondary hemostasis is coagulation. [slideshare.net]
Treatment
The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]
Under conservative treatment without anticoagulation and aspirin, the patient made a good recovery within a few months. [ncbi.nlm.nih.gov]
Treatments depend on the cause. They may include medicines and transfusions of blood, platelets, or clotting factor. [icdlist.com]
Prognosis
Prognosis Prognosis is good for patients with congenital dysfibrinogenemias. Events of bleeding or thrombosis are usually relatively mild. Acquired dysfibrinogenemia carries a worse prognosis because it is due to a severely damaged liver. [emedicine.medscape.com]
In a series of 130 patients with pureLMS, most cases showed an excellent prognosis, withthe exception of 1 patient (0.8%) who died during hospi-talization [13]. [docslide.com.br]
"Diagnosis, pathogenesis, treatment, and prognosis of hereditary fibrinogen A alpha-chain amyloidosis". Journal of the American Society of Nephrology : JASN. 20 (2): 444–51. doi : 10.1681/ASN.2008060614. PMC 2637055. PMID 19073821. [en.wikipedia.org]
Expectations (prognosis) The outcome depends on the disorder causing the low platelet counts. [slideshare.net]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
The first chapter stresses the etiology and pathophysiology of childhood stroke as the basis for evaluations and treatment. [books.google.com]
Because mutations in ion channel genes have been recognized as an important factor in the etiology of abnormal neuron... [wwe.geoscience.net]
Etiology The etiology of thrombophilia can be classified into two categories: References: [1] Clinical features Thrombophilia is characterized by recurrent thromboembolisms. [amboss.com]
The most common etiology is disease of the liver or biliary tract. [clinlabnavigator.com]
Epidemiology
Many epidemiological studies have reported an association between coronary heart disease (CHD) and various “inflammatory” factors, including plasma levels of fibrinogen, C-reactive protein, albumin, and white blood cell (WBC) count. [clinlabnavigator.com]
Background : Numerous mutations in, or lead to congenital fibrinogen disorders (CFDs), but their epidemiology is not well characterized. The aim of this study was to evaluate the molecular epidemiology of CFD and to develop a genotyping strategy. [pubfacts.com]
Emicrania e trombofilia Epidemiological studies suggest that migraine is associated with disorders of the cerebral, coronary, retinal and peripheral vasculature. [slideshare.net]
Epidemiology Congenital dysfibrinogenemia has been reported in only 200-300 families. Transmission is autosomal dominant or codominant, except in a few cases that appear to be transmitted recessively. [emedicine.medscape.com]
Pathophysiology
Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke. [books.google.com]
The hereditary dysfibrinogenemias are the first coagulation disorder in which the pathophysiology has been elucidated on a molecular level. [ncbi.nlm.nih.gov]
About 26% of individuals with the disorder suffer both bleeding and thrombosis complications. [5] [14] Pathophysiology [ edit ] Congenital dysfibrinogenemia is most often caused by a single autosomal dominant missense mutation in the Aα, Bβ, or γ gene [en.wikipedia.org]
Prevention
Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more. [books.google.com]
Inadults, aspirin is recommended for secondary preven-tion of ischemic stroke, but no randomized, clinical tri-als for primary prevention, short-term treatment orsecondary prevention of pediatric arterial ischemicstroke have been described. [docslide.com.br]
With ischemic stroke to prevent recurrent stroke, MI, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 2004;291:565-575. 20. [slideshare.net]
In addition, appropriate medical treatment for the systemic cause is necessary and may help prevent recurrences of thromboembolic disease in the eye and elsewhere. [reviewofoptometry.com]
For some bleeding disorders, there are treatments that can be taken at home to prevent or treat bleeds. With appropriate education and treatment, people with bleeding disorders can live full and productive lives. [cslbehring.com]