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2.1
Hereditary Koilonychia
Spoon Nails

Presentation

A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories. [books.google.de]

More Idiopathic onycholysis A middle-aged lady presented with onycholysis involved all fingernails of one year duration. [dermatologyoasis.net]

[…] pseudoainhum formation can be ruled out due to the presence of autoamputation of digits in the present case [Figure 3]. [jdrntruhs.org]

[…] shift of water from interstitial fluid compartment to intra-vascular compartment A 5 year old patient presents w/ a fever and has a history of bleeding and fatigue. [quizlet.com]

Entire Body System

  • Nail Abnormality

    Koilonychia is a component of the nail-patella syndrome, a genetic disease characterized by numerous abnormalities including musculoskeletal and kidney abnormalities. [medicinenet.com]

    Aging changes in hair and nails (Medical Encyclopedia) Fungal nail infection (Medical Encyclopedia) Ingrown toenail (Medical Encyclopedia) Ingrown toenail removal - discharge (Medical Encyclopedia) Nail abnormalities (Medical Encyclopedia) Nail injuries [icdlist.com]

    There is no other family history of hair or nail abnormalities. On physical examination, the well-developed and well-nourished boy has appropriate behavior for age. [pedsinreview.aappublications.org]

    Brachydactyly with short cone-shaped fingers and nail abnormalities, such as koilonychia or pachyonychia, are frequently associated features. [jamanetwork.com]

    Nail abnormalities: clues to systemic disease. Am Fam Physician. 2004; 69(6):1417-24. 8. Kumar G, Vaidyanathan L, Stead LG. Images in emergency medicine. Koilonychia, or spoon-shaped nails, is generally associated with iron-deficiency anemia. [podiatrytoday.com]

Workup

The presence of koilonychia should prompt further workup for an underlying systemic or environmental cause. References 1. Barnett JM, Scher RK, Taylor SC. Nail cosmetics. Dermatol Clin. 1991; 9(1):9-17. 2. Lembach L. Pediatric nail disorders. [podiatrytoday.com]

Note – the doctor must be aware of the potential systemic and cutaneous associations with this condition in order to guide appropriate treatment, workup, and referral. [yourhealthremedy.com]

[…] associated with nail involvement. [22], [35] Hence, nail findings may not only be window to a plethora of possible systemic associations, but also a window of opportunity as a profound knowledge of the associations may be useful in a complete and targeted workup [idoj.in]

Treatment

CLOSE Medical Disclaimer The medical information on this site is provided as an information resource only, and is not to be used or relied on for any diagnostic or treatment purposes. [diseaseinfosearch.org]

Treatment is focused on removing excess metal by repeated bloodletting and the use of oral chelators. [scielo.br]

Once a periungual wart diagnosis is made, the podiatrist may recommend one of several treatment options. Those options include laser treatments, salicylic treatments, topical creams and cryotherapy. [boyntonfeet.com]

Spoon nails can also be caused by the following reasons: Picking/biting of the nails Nail trauma Hereditary predisposition Fungus Other health problems such as cardiorespiratory issues Treatment of Spoon Nails: Spoon nail treatment depends on the cause [nailcare.ygoy.com]

CURRENT NAIL-TREATMENT STRATEGIES The indications for treatment of pincer and ingrown nails are pain, inflammation, interference with wearing shoes, and cosmetic embarrassment. [journals.lww.com]

Prognosis

Prognosis - Hereditary koilonychia Not supplied. Treatment - Hereditary koilonychia Not supplied. Resources - Hereditary koilonychia Not supplied. [checkorphan.org]

Prognosis The prognosis of mixed connective tissue disease is in most cases worse than that of systemic lupus erythematosus (SLE) in spite of prednisone treatment as this disease is progressive and may in many cases evolve into a progressive systemic [findzebra.com]

Phenotype and prognosis in monilethrix due to mutations of hair keratins hHb 1 and hHb 6. Br J Dermatol 1999; 141 Suppl. 55: 102–7 Google Scholar 6. Zlotogorski A, Christiano AM. Mapping of monilethrix and papular atrichia [letter]. [link.springer.com]

Congestive heart failure can develop rapidly, but prognosis improves drastically if iron is removed before concentrations reach critical levels. [clinicaladvisor.com]

[…] palmoplantar keratodermas (PPKs) are a group of heterogeneous skin disorders classified based upon their mode of inheritance, age of onset, morphology and distribution of palmoplantar thickening, presence of skin lesions elsewhere, histopathology, and prognosis [jdrntruhs.org]

Etiology

[…] trichothiodystrophy, LEOPARD syndrome, Darier’s disease and nail-patella syndrome. 2 Familial koilonychias is a rare genetic disease that is not associated with other ectodermal, systemic or orthopedic defects. 3 There are several theories regarding the etiology [podiatrytoday.com]

There are different ways to classify nail disorders and a compromise between a scientifically based etiologic classification and a more clinico-morphologically based one appears to be a practical approach to nail disorders. [accessmedicine.mhmedical.com]

Koilonychia Causes Persons with this kind of condition, specifically koilonychia, have acquired the condition because of the following associated causes or etiological factors: Chronic iron deficiency anemia Hereditary forms such as: Adenoma sebaceum [healthzene.com]

The etiology of ASM is not well understood but there is evidence of an activating mutation of KIT, usually D816V, in the mast cells of the vast majority of patients with ASM. [findzebra.com]

- Other signs may correlate more closely to specific anemia etiologies, for instance:. .. Cavernous hemangioma: microangiopathic hemolytic anemia. .. Lower extremity ulcers: sickle cell disease. .. [hawaii.edu]

Epidemiology

Association Between Psoriasis and Sexual and Erectile Dysfunction in Epidemiologic Stud... Preview https://www.ncbi.nlm.nih.gov/pubmed/30304327 JAMA Dermatology; Molina-Leyva A, Salvador-Rodriguez L et. al. [allmedx.com]

30058568 A prospective study of the epidemiological and clinical patterns of recurrent dermatophytosis at a tertiary care hospital in India. 30058567 Onychomatricoma: Clinical, dermoscopy and ultrasound findings. 30058566 Asymptomatic erythematous plaques [nlm.life]

[…] age in developing countries. [ 2 ] The World Health Organization defines anaemia as: [ 1 ] Haemoglobin (Hb) Hb Hb Failure to investigate IDA appropriately in primary care can cause significant delay in final diagnosis, with associated morbidity. [ 3 ] Epidemiology [patient.info]

The Food and Nutrition Policy General Committee of the Ministry of Health addressed the epidemiological relevance of this issue and reported that, despite of not having complete national figures, studies show that approximately half of Brazilian preschool [scielo.br]

Diagnosis and epidemiology of cirrhosis. Med Clin North Am 2009;93:787–99, vii. Brissot P, Ball S, Rofail D, et al. Hereditary hemochromatosis: patient experiences of the disease and phlebotomy treatment. Transfusion 2011;51:1331–8. [bpac.org.nz]

Pathophysiology

Pathophysiologically, when the SLURP-1 protein is non-functional, hyperkeratosis results due to improperly regulated keratinocyte apoptosis and the macrophage and keratinocyte release of tumor necrosis factor (TNF)-a is inhibited producing generalized [odermatol.com]

Although the pathophysiology of the cellular and tissue responses of the nail to mechanical force remains unknown, our hypothesis is a new concept that could lead to innovative methods that prevent and treat nail deformities. REFERENCES 1. [journals.lww.com]

The book explains disease processes according to presenting symptoms, treatment options and tiers, and pathophysiology sections. The final updates for the 17th edition are dated October 2, 2007. So, this is a relatively current resource. [clinicaladvisor.com]

Prevention

Causes - Hereditary koilonychia * Concave nails * Thin nails Prevention - Hereditary koilonychia Not supplied. [checkorphan.org]

Prevention of koilonychias Prevention is better than cure. In family members suffering from this problem, those who have not developed can follow certain preventive techniques. [beautyhealthtips.in]

There are many ways that this condition can be prevented. [toenailfungi.org]

Methods for treating or preventing Koilonychia include: For abnormalities because of toenails that are ingrown, wear types of shoes that do not crowd together the toes as well as always cut the toenails straight across the top. [symptomscausestreatmentprevention.blogspot.com]

Prevention of neural tube defects using folic acid In 1991 the MRC Vitamin Study Research Group published a major work on the prevention of neural tube defects with folic acid.(28) This is a cooperative group formed by 33 medical centers in seven nations [scielo.br]

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2.1
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