Compared to young onset PD (YOPD; see this term), a higher risk of developing gait freezing and falls but a lower risk of developing dystonia, dyskinesia and LID have been reported. [orpha.net]

Late-Onset Parkinson Disease: 60 33 (show all 35) # Description HPO Frequency Orphanet Frequency HPO Source Accession 1 diplopia 60 33 frequent (33%) Frequent (79-30%) HP:0000651 2 dysphagia 60 33 frequent (33%) Frequent (79-30%) HP:0002015 3 frequent falls [malacards.org]

Patients with previous falls often develop fear of falling which further limits their mobility, contributing to increased weakness and deterioration. [hindawi.com]

EFNS/ MDS [3] – Level II Falls and fear of falling General elderly recommendations. EFNS/ MDS [3] – Level IV Physical activity and exercise for near falls. MDS [6] – Level II EFNS/ MDS [3] – Level II Physical activity and exercise for falls. [scielo.br]

Avoiding fall s In advanced stage of illness, there is always a risk of getting injured as a result of sudden loss of balance. Few precautions can help a great deal from losing balance and preventing falls. [newhealthadvisor.com]

Fatigue. Many people with Parkinson's disease lose energy and experience fatigue, especially later in the day. The cause isn't always known. Pain. [mayoclinic.org]

Extreme fatigue is always present, and even the smallest physical effort (or a mental stress) turn my morning leg tremors into full body uncontrollable twitching and bending... [caring.com]

The symptoms of dystonia typically increase during stress, emotional upset or fatigue, and decrease during rest and sleep. Many people living with dystonia can temporarily suppress their symptoms by using “sensory tricks”. [dystonia-parkinsons.org]

Symptoms of Hemochromatosis Symptoms of Hemochromatosis Symptoms of Hemochromatosis Chronic fatigue and joint pain are the most common complaints of people with hemochromatosis. [hemochromatosis.org]

The Non-Motor Symptoms Scale, for instance, is a 30-item scale for assessment of nine dimensions (cardiovascular, sleep/fatigue, mood/cognition, perceptual problems, attention/memory, gastrointestinal, urinary, sexual function, and miscellany), that has [hindawi.com]

She had suffered from chronic leg edema, especially on the right side. Skin biopsy on the right posterior thigh showed irregular vascular channels lined by atypical endothelial cells. [kiss.kstudy.com]

The lymphedema on both lower extremities after uterine cervical cancer treatment was aggravated especially on the right lower extremity after right total hip replacement surgery. [kiss.kstudy.com]

She showed a pelvic mass and pelvic bone metastasis on radiologic staging work-up. She refused all treatment, including surgery, radiotherapy, and chemotherapy, except for pain control. [kiss.kstudy.com]

혈관각화종(angiokeratoma)은 각질층의 증식과 혈관 확장 및 증식을 특징으로 하여 본 증례와 임상적으로 유사하다. 병리조직학적으로 혈관기형에 속하며, 유두진피에 심하게 확장된 모세혈관과 혈관 내 혈전이 관찰될 수 있어 본 증례와는 차이가 있다5. 치료는 두 증례에서 외과적 절제술을 시행하였고, 그 외 전기소작술 또는 레이저치료를 시행할 수 있다. [kiss.kstudy.com]

다운로드 (기관인증 필요) 초록보기 Background: Postinflammatory hyperpigmentation (PIH) is one of the most common adverse effects associated with dermatologic procedures, especially those for cosmetic purposes. [kiss.kstudy.com]

Patients with hereditary LOPD are also more affected by severe diplopia, cognitive impairment, and gastrointestinal and urinary disorders. [orpha.net]

Late-Onset Parkinson Disease Symptoms & Phenotypes for Hereditary Late-Onset Parkinson Disease Human phenotypes related to Hereditary Late-Onset Parkinson Disease: 60 33 (show all 35) # Description HPO Frequency Orphanet Frequency HPO Source Accession 1 diplopia [malacards.org]

LOPD patients report a lower prevalence of non-motor symptoms such as depression, hallucinations, behavioral disturbances (i.e. agitation or impulse control disorder), dementia and apathy. [orpha.net]

(7.5%) Occasional (29-5%) HP:0002063 17 agitation 60 33 occasional (7.5%) Occasional (29-5%) HP:0000713 18 bradykinesia 60 33 occasional (7.5%) Occasional (29-5%) HP:0002067 19 shuffling gait 60 33 occasional (7.5%) Occasional (29-5%) HP:0002362 20 impulsivity [malacards.org]

Impulsive and compulsive behaviour can be a side-effects and are more common with this group of medicines than with levodopa. [patient.info]

It sends electrical impulses into the brain to help control tremors and twitching movements. Some people may need surgery to manage Parkinson disease symptoms. Surgery may involve destroying small areas of brain tissue responsible for the symptoms. [hopkinsmedicine.org]

Trial of CBT for impulse control behaviors affecting Parkinson patients and their caregivers. Neurology. 2013 Feb 26. 80(9):792-799. [Medline]. [Full Text]. Anderson P. Cognitive Therapy Controls Impulse Behaviors in Parkinson's. Available at . [emedicine.medscape.com]

0002015 3 frequent falls 60 33 frequent (33%) Frequent (79-30%) HP:0002359 4 hyposmia 60 33 frequent (33%) Frequent (79-30%) HP:0004409 5 parkinsonism with favorable response to dopaminergic medication 60 33 frequent (33%) Frequent (79-30%) HP:0002548 6 akinesia [malacards.org]

Other characteristic symptoms of Parkinson disease include rigidity or stiffness of the limbs and torso, slow movement (bradykinesia) or an inability to move (akinesia), and impaired balance and coordination (postural instability). [ghr.nlm.nih.gov]

gait 60 33 occasional (7.5%) Occasional (29-5%) HP:0002362 20 impulsivity 60 33 occasional (7.5%) Occasional (29-5%) HP:0100710 21 orthostatic hypotension due to autonomic dysfunction 60 33 occasional (7.5%) Occasional (29-5%) HP:0004926 22 apathy 60 [malacards.org]

Neuronal loss in central nervous system MedGen UID: 342515 •Concept ID: C1850496 • Finding Short stepped shuffling gait MedGen UID: 812045 •Concept ID: C3805715 • Finding Weak voice MedGen UID: 66033 •Concept ID: C0241700 • Finding Reduced intensity [ncbi.nlm.nih.gov]

29-5%) HP:0000741 23 hypomimic face 60 33 occasional (7.5%) Occasional (29-5%) HP:0000338 24 postural instability 60 33 occasional (7.5%) Occasional (29-5%) HP:0002172 25 visual hallucinations 60 33 occasional (7.5%) Occasional (29-5%) HP:0002367 26 monotonic [malacards.org]

Occasional (29-5%) HP:0002172 25 visual hallucinations 60 33 occasional (7.5%) Occasional (29-5%) HP:0002367 26 monotonic speech 60 33 occasional (7.5%) Occasional (29-5%) HP:0031435 27 lewy bodies 60 33 occasional (7.5%) Occasional (29-5%) HP:0100315 28 gliosis [malacards.org]

Substantia nigra gliosis MedGen UID: 337668 •Concept ID: C1846865 • Finding Focal proliferation of glial cells in the substantia nigra. [ncbi.nlm.nih.gov]