A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. [icd10data.com]

Visual field testing reveals a central or cecocentral scotoma and color vision defects. In the acute phase the disc can be swollen and hyperemic. [disorders.eyes.arizona.edu]

Visual fields revealed a centrocecal scotoma smaller than 10 in both eyes. F igure 2. [iovs.arvojournals.org]

Humphrey visual field test shows cecocentral scotoma in right eye and central scotoma in left eye. [eyewiki.aao.org]

Swelling of the optic nerve head, vascular tortuosity, peripapillary telangiectasia, microangiopathy and central scotomas on visual field testing are all signs of LHON. [orpha.net]

This first volume covers the visual sensory system, the autonomic nervous system, the ocular motor system, the eyelid, facial pain and headache, and nonorganic disease. Volume 2 covers tumors, the phacomatoses, and vascular disease. [books.google.com]

We have found a much reduced activity of this enzyme in liver biopsies from two affected males of a family with Leber's hereditary optic atrophy and in two isolated cases of the same disease, (compared to liver biopsies from controls or liver samples [ncbi.nlm.nih.gov]