Most lesions had been progressively increased in size and number with time, but he was asymptomatic. In family history, his father had similar symptoms and died in his fourties due to cardiovascular disease. [ncbi.nlm.nih.gov]

Physical examination revealed micrognathia (Fig. 1A), clubbing fingers (Fig. 1B), and slim extremities compared with trunk (Fig. 1C). [ncbi.nlm.nih.gov]

Mutations in FAM111B cause hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis. [pubmed.ncbi.nlm.nih.gov]

The widespread poikiloderma characterized by speckled hypopigmentation and hyperpigmentation, slight atrophy, and minimal telangiectasia mainly involves in the flexural areas and over bony prominences (2). [ncbi.nlm.nih.gov]

Kindler syndrome Other names Congenital poikiloderma with blisters and keratoses,[1] Congenital poikiloderma with bullae and progressive cutaneous atrophy,[1] Hereditary acrokeratotic poikiloderma,[1] Hyperkeratosis–hyperpigmentation syndrome,[2]:511 [en.wikipedia.org]

The hypo- and hyperpigmentation may suggest EB simplex with mottled pigmentation or hereditary poikilodermas. The latter differential diagnoses may be considered if photosensitivity is prominent. Acquired disorders may mimic KS. [dermatologyadvisor.com]

As individuals with Kindler syndrome age, they tend to have fewer problems with blistering and photosensitivity. [en.wikipedia.org]

Characteristic findings on clinical examination Skin blistering begins at birth and persists during childhood, but progressively decreases with age. [dermatologyadvisor.com]

Although cutaneous manifestations associated with mandibuloacral dysplasia were similar to those associated with HSP, the extracutaneous manifestations in our patient were not found in association with mandibuloacral dysplasia. [ncbi.nlm.nih.gov]

It is absent at birth and first appears within the second to fourth yr of life without prior vesiculation or eczema and progressively worsens with increasing time. [ncbi.nlm.nih.gov]

Because of skin atrophy and sclerosis, junctional or dystrophic EB may be suspected; however, in those conditions, poikiloderma is not a feature. [dermatologyadvisor.com]

Previously reported cases suggest that the diagnosis for HSP requires the presence of the above two features and other clinical features are not essential to diagnosis (3). [ncbi.nlm.nih.gov]

We refer to gastroenterology when symptoms suggest the presence of oesophageal strictures. We do not recommend a baseline examination or regular check. [dermatologyadvisor.com]