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Herpesviridae


Presentation

  • METHODS: Aqueous humor samples were collected from 42 patients suspected of having AU of infectious origin at presentation.[ncbi.nlm.nih.gov]
  • The histologic findings of HSV, when present, are pathognomonic.[archivesofpathology.org]
  • We are currently sequencing the full genome of HHV-4 present in human saliva using both Roche 454 and Illumina sequencing technology.[sanger.ac.uk]
  • While previous studies have focused on the effect of individual infectious exposure, namely, Herpesviridae viruses or Toxoplasma gondii (T gondii), on cognitive functioning, the objective of the present study was to examine the effect of multiple infections[ncbi.nlm.nih.gov]
Anterior Uveitis
  • Among them five anterior uveitis were CMV-associated: Posner Schlossman syndrome (n 1), hypertensive anterior uveitis without iris atrophy (n 3) or non granulomatous normotensive anterior uveitis without iris atrophy (n 1), by intraocular biological testing[iovs.arvojournals.org]
  • PURPOSE: To target the use of two biologic tests in the diagnostic of viral Herpesviridae anterior uveitis (AC) by the consideration of clinical behavior and delay of intraocular sampling.[ncbi.nlm.nih.gov]
  • Not only anterior uveitis but one related study also revealed a high frequency of positive results without complications from aqueous analysis among patients with posterior uveitis.[dovepress.com]
Neglect
  • Another advantage of implementing this test would be that the wide range of viruses tested could help assess the pathogenicity of neglected viruses such as HHV-7, which was the most commonly identified virus in our cohort after CMV, EBV, and HHV-6.[jcm.asm.org]
  • […] did occur. 23,24 Protracted fever and asthenia may provoke considerable anxiety if diagnosis is not rapidly established. 15,25,26 Finally, besides their substantial acute morbidity, long‐term consequences of CMV and T gondii infections should not be neglected[doi.org]

Workup

  • Therefore, combination of classic predictors is necessary to increase substantially the posttest probability of a first‐line workup. Precise etiologic diagnosis requires serological testing against all four commonly associated pathogens.[doi.org]
Complement Fixing Antibody
  • Patterns of cytomegalovirus complement-fixing antibody activity: A longitudinal study of blood donors. J. Infect. Dis. 127 : 538 – 543. PubMed CrossRef Google Scholar Weller, T. H., et al. 1971.[link.springer.com]
Treponema Pallidum
  • Other infectious agents such as Mycobacterium tuberculosis , Treponema pallidum , Cryptococcus neoformans , Lysteria monocytogenes , Brucella spp. , Mycoplasma, neurocysticercosis, leptospirose or non infectious conditions including autoimmune diseases[scielo.br]

Treatment

  • Treatment: DHPG [9-(l,3-dihydroxy-2-propoxymethy)guanine] is an effective antiviral agent that suppresses CMV during treatment, but does not eradicate it.[link.springer.com]
  • HSV as a Treatment Vector for Cancer HSV has been an object of interest into research and development as a treatment vector for cancer.[microbewiki.kenyon.edu]
  • […] status was: Recruiting First Posted : June 2, 2014 Last Update Posted : December 2, 2017 Sponsor: Information provided by (Responsible Party): Assistance Publique Hopitaux De Marseille Brief Summary: The aim of this study is to show that a preemptive treatment[clinicaltrials.gov]
  • For each viral pathogen, we will describe the epidemiology, natural history, screening and diagnosis modalities, treatments, and implications for antepartum care.[journals.lww.com]

Prognosis

  • Advances in the technology available for the diagnosis of B virus infection and in the agents for its treatment are improving the prognosis for cases in human beings.[doi.org]
  • Finally, primary HIV infection is also a crucial diagnosis to consider in febrile travelers. 18 Early diagnosis of acute HIV infection would allow fast interventions aimed at improving its long‐term prognosis and at reducing its secondary spreading.[doi.org]
  • The tortoises died either during the spring (April-June: n 8) or the fall (October-December: n 4) including also Z02/1970 that was euthanized because of very poor prognosis.[dx.plos.org]

Etiology

  • CONCLUSIONS: While the GWC is progressively less often performed, these findings suggest that it still has a role in AU suspected of herpesvirus etiology.[ncbi.nlm.nih.gov]
  • Consequently, a single herpesvirus species can be attributed to a wide range of diseases as etiological agents or cofactors.[intechopen.com]
  • To address the important issue of the prevalence of CMV etiology among cohort of patients with severe anterior uveitis of unclear diagnosis.[iovs.arvojournals.org]
  • There is little information on the etiology of viral meningitis in Brazil especially in the Southern region.[scielo.br]

Epidemiology

  • For each viral pathogen, we will describe the epidemiology, natural history, screening and diagnosis modalities, treatments, and implications for antepartum care.[journals.lww.com]
  • HSV: herpes simplex virus IV: intravenous PCR: polymerase chain reaction SEM: skin, eye, and mouth STI: sexually transmitted infection VZV: varicella-zoster virus Objectives After completing this article, readers should be able to: Characterize the epidemiology[doi.org]
  • Unfortunately, the epidemiology of B virus in group-housed macaques is poorly understood.[doi.org]
  • The findings of the present study have contributed to a better understanding of the epidemiology of these viruses in this region.[scielo.br]
  • Radford 1 Department of Epidemiology, Emory University, and Centers for Disease Control and Prevention, Atlanta, Georgia Search for other works by this author on: W.[doi.org]
Sex distribution
Age distribution

Pathophysiology

  • Biology and Pathophysiology The Herpesviridae family includes viruses that infect animals and humans (Siakallis 2009). Among these viruses, eight members are known to infect humans and are clinically important (Siakallis 2009).[lifeextension.com]
  • HSV infection is mediated through attachment via ubiquitous receptors to cells, including sensory neurons, leading to establishment of latency. [1] Pathophysiology HSV-1 and HSV-2 are characterized by the following unique biological properties: [1] Neurovirulence[emedicine.medscape.com]

Prevention

  • Alternatively, vaccine in those with latent HSV could prevent reactivation, recurrent disease, and transmission. Clinical HSV vaccine trials should define clearly the types of protection being measured.[creative-biolabs.com]
  • Concept for Epstein-Barr virus infection treatment and prevention Cytomegalovirus CMV, a DNA virus from Herpesviridae family. 3D illustration.[shutterstock.com]
  • Prevention and Control: Infection can be prevented by avoiding close personal contact (including sexual) with an actively infected individual.[link.springer.com]
  • Article Navigation 1 Department of Epidemiology, Emory University, and Centers for Disease Control and Prevention, Atlanta, Georgia 2 Centers for Disease Control and Prevention, Atlanta, Georgia Reprints or correspondence: Stephanie A. S.[doi.org]

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