Either hetastarch, when present at concentrations comparable to the manufacturer's maximum recommended dose of 20 mL/kg (equivalent to the high dilution used in these experiments), decreases clot tensile strength to levels associated with an increased [ncbi.nlm.nih.gov]

Presentations will also address emergency preparedness from the processing facilities perspective and response to critical reagent shortages. [celltherapysociety.org]

The material is presented in a brief and quick-access format which allows for topic and exam review. It provides enough detailed and specific information to address most all questions and problems that arise in the ICU. [books.google.de]

• Intravenous Administration

  HESPAN ® (6% Hetastarch in 0.9% Sodium Chloride Injection), 500 mL EXCEL ® IV container HESPAN ® (6% hetastarch in 0.9% sodium chloride injection) is a sterile, nonpyrogenic solution for intravenous administration. [bbraunusa.com]

  ➤ License Authorization Form (LAF) Required HESPAN® (6% hetastarch in 0.9% sodium chloride injection) is a sterile, nonpyrogenic solution for intravenous administration. [boundtree.com]

  Upon intravenous administration, hydroxyethyl starch colloid increases blood volume and thus improves circulation. This agent is almost exclusively excreted by the kidneys and is potentially nephrotoxic. [cancer.gov]

  Intended for intravenous administration using sterile equipment. It is recommended that intravenous administration apparatus be replaced at least once every 24 hours. [medlibrary.org]

Sepsis / Shock, Septic 1 4 Completed Treatment Subarachnoid Hemorrhage 1 4 Recruiting Treatment Hypovolaemia 1 4 Recruiting Treatment Hypovolaemia Due to Acute Blood Loss 1 4 Terminated Treatment Anaesthesia therapy 1 4 Terminated Treatment Intraoperative [drugbank.ca]

This study shows an increase in coagulopathy with the use of hetastarch as compared with the use of PPF for the treatment of postaneurysmal vasospasm. [ncbi.nlm.nih.gov]

The expected benefit of treatment should be carefully weighed against the uncertainties with regard to long-term safety, and other available treatment options should be considered. [ema.europa.eu]

Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.de]

Two studies in cardiac surgery patients and an epidemiological study from the current literature prompted the FDA to ask if hetastarch mediates increased bleeding in patients on cardiopulmonary bypass. [anesthesiology.pubs.asahq.org]

[…] the Department of Anesthesiology and Intensive Care Medicine (F.M.B., F.B., C.H., K.R.) and the Institute of Clinical Chemistry and Laboratory Medicine (M.K.), Friedrich Schiller University, Jena; the Institute of Medical Informatics, Statistics and Epidemiology [doi.org]

Pathophysiology is emphasized throughout, providing a sound basis for discussions of the diagnosis, treatment, and prognosis that follow. [books.google.de]

The pathophysiological basis for pruritus is the widespread tissue deposition of HES, prominently in macrophages. HES tissue deposits are long lasting and sometimes massive. [ncbi.nlm.nih.gov]

The increase in creatinine confirmed the pathophysiological rationale. Furthermore, the patients needed more blood products, had significant more liver failure and itching. The study was published in the NEJM in October 2012.. [en.wikipedia.org]

One potential mechanism for adverse outcomes that could be modified by the administration of colloids is the unique pathophysiology associated with hip and knee arthroplasties. [bmj.com]

IMPLICATIONS: This prospective, randomized, blinded trial showed that, in elderly surgical patients, the use of balanced IV solutions can prevent the development of hyperchloremic metabolic acidosis and provide better gastric mucosal perfusion compared [ncbi.nlm.nih.gov]

Complications Associated With Artificial Fertilization / Disorder of Endocrine Ovary 1 0 Not Yet Recruiting Prevention Hypotension Drug-Induced 1 2 Completed Prevention Coagulation Defect; Bleeding 1 2 Completed Treatment Angina Pectoris / Myocardial [drugbank.ca]