License Authorization Form (LAF) Required HESPAN (6% hetastarch in 0.9% sodium chloride injection) is a sterile, nonpyrogenic solution for intravenous administration. [boundtree.com]

Upon intravenous administration, hydroxyethyl starch colloid increases blood volume and thus improves circulation. This agent is almost exclusively excreted by the kidneys and is potentially nephrotoxic. [cancer.gov]

HESPAN (6% Hetastarch in 0.9% Sodium Chloride Injection), 500 mL EXCEL IV container HESPAN (6% hetastarch in 0.9% sodium chloride injection) is a sterile, nonpyrogenic solution for intravenous administration. [bbraunusa.com]

This solution is intended for intravenous administration using sterile equipment. It is recommended that intravenous administration apparatus be replaced at least once every 24 hours. Use only if solution is clear and container and seals are intact. [dailymed.nlm.nih.gov]

However, in patients receiving HEX, initial heart rate was higher, base deficit was lower, and hematocrit was lower (consistent with relative hypovolemia), even though blood product requirements were reduced, and urine output was greater (all p 0.05). [ncbi.nlm.nih.gov]

At 72 hours, brains were removed, and brain edema and brain tissue necrosis volume were determined. [ncbi.nlm.nih.gov]