A 77-year-old man with chronic obstructive lung disease who was on steroids, presented to the hospital after a fall with subacute headaches and ataxia. [jhu.pure.elsevier.com]

Central nervous system (CNS) involvement is present in 5%–10% of patients with disseminated histoplasmosis [ 1, 2 ]. Clinical presentations include meningitis, hydrocephalus, brain or spinal cord mass lesions, stroke, and encephalitis. [academic.oup.com]

Oligoclonal bands were present. CSF stains and bacterial cultures were negative; fluid was held for acid-fast bacilli and fungal cultures. [journals.lww.com]

The present study of 5 adults represents a beginning attempt to define the laboratory, clinical, and therapeutic aspects of histoplasma meningitis. [annals.org]

• Fever

  Fever and Skin Rash 292 Fever and the Renal Transplant Recipient 301 Fever Following Travel Abroad 306 Hyperpyrexia and Hyperthermia 316 Fever in the Granulocytopenic Patient 319 Fever of Unknown Origin 325 Recurrent Furunculosis 333 Postoperative Fever [books.google.de]

  During the patient's hospital course, his clinical condition deteriorated with myoclonic jerks, fevers and severe encephalopathy. An extensive workup, including EEG, brain MRI and lumbar puncture, revealed possible Creutzfeldt-Jakob disease. [jhu.pure.elsevier.com]

  Valley Fever and Pregnant Women. State of California Health and Human Services Agency. January 2016. Valley Fever Statistics. CDC. November 9, 2017. Thomas M. The Mysterious Fungus Infecting the American Southwest. The Atlantic. August 8, 2014. [everydayhealth.com]

• Weight Loss

  While diarrhea, weight loss, and lethargy are common, Campylobacteriosis can also be present in birds that show no symptoms of illness. [petassure.com]

  If symptoms are present, they can include fever, tiredness, weight loss, difficult breathing, chest pain, dry cough, headache, anemia, and enlargement of the liver, spleen and lymph nodes. More symptoms are possible the more the disease spreads. [poz.com]

  If the disease progresses without treatment, those affected may develop weight loss, shortness of breath, and fatigue. Ocular (eye) involvement in disseminated disease can cause loss of vision. [medicinenet.com]

  People with chronic disseminated histoplasmosis experience mild intermittent fever, weight loss, weakness, anaemia and enlargement of the liver and spleen. [conditions.health.qld.gov.au]

  Symptoms: Fever Fatigue Shortness of breath Cough Weight loss Diagnosis: Finding the organism in a sample of blood, sputum (spit), or other tissue Treatment: Initial treatment with intravenous amphotericin B, then switch to long-term therapy with oral [thewellproject.org]

• Chills

  In people, the disease causes flu-like symptoms of fever, chills and headache. If left untreated, Psittacosis can cause liver and kidney damage or even meningitis. [petassure.com]

  While for most, the only sign of being infected will be small scars on the lungs, but for others, the paroxysmal stage can include: fever, muscle aches, headache, dry cough, chills, chest pain, loss of appetite, and/or sweats. [austincc.edu]

  The symptoms of pulmonary histoplasmosis are similar to those of pneumonia and include flu-like symptoms such as fever, chills, sweats, a dry cough, malaise, and chest pains. Some affected people also experience joint pains. [medicinenet.com]

  If a person does become unwell with histoplasmosis, the disease may appear in any of four different forms: Acute respiratory - the illness varies from a mild respiratory illness to feeling generally very unwell with symptoms of tiredness, high fever, chills [conditions.health.qld.gov.au]

  Symptoms can appear with in 1 week and include fever, chills, headache, non productive cough, myalgia, chest pain, loss of appetite and fatigue. Infection is usually asymptomatic for low level exposure or mild infections. [msdsonline.com]

• Malaise

  Clinical manifestations include headache, fever, malaise, photophobia, and meningeal signs. [genome.jp]

  […] include fever, headache, nonproductive cough, chills, pleuritic chest pain, weight loss, malaise, myalgias, and sweats. [aafp.org]

  The symptoms of pulmonary histoplasmosis are similar to those of pneumonia and include flu-like symptoms such as fever, chills, sweats, a dry cough, malaise, and chest pains. Some affected people also experience joint pains. [medicinenet.com]

  Fever and other systemic findings are characteristic (chills, fever, anorexia, malaise, diarrhea, weight loss, hepatosplenomegaly, anemia, leukopenia, thrombocytopenia). Sepsis syndrome with ARDS can be seen. [clinicaladvisor.com]

  The symptoms of disseminated histoplasmosis include fever, malaise, anorexia, and weight loss. [cmr.asm.org]

• Cerebral Palsy

  In developed countries, the rate of mortality from bacterial meningitis among neonates has decreased but there has not been a significant decrease in long-term complications such as cerebral palsy, learning disability, seizures and hearing impairment. [patient.info]

  palsy, chronic pulmonary disease, hepatitis C, malignancy, pregnancy, and head trauma in 1 patient each. [academic.oup.com]

• Furunculosis

  Fever and Skin Rash 292 Fever and the Renal Transplant Recipient 301 Fever Following Travel Abroad 306 Hyperpyrexia and Hyperthermia 316 Fever in the Granulocytopenic Patient 319 Fever of Unknown Origin 325 Recurrent Furunculosis 333 Postoperative Fever [books.google.de]

• Headache

  A 77-year-old man with chronic obstructive lung disease who was on steroids, presented to the hospital after a fall with subacute headaches and ataxia. [jhu.pure.elsevier.com]

  Duarte, 3 in 1945, reported the case of a 23-year-old woman with headache, photophobia, nausea, and vomiting but no signs of meningeal irritation. At autopsy, the patient had a basilar meningeal exudate and lesions in [jamanetwork.com]

  CASE REPORT In March 2011, our patient sought medical attention at an outside hospital emergency room following a 2-month history of weekly morning headaches. Headaches were followed by emesis and a period of sleepiness. [journals.lww.com]

• Confusion

  During 1972, increasing frequency of these episodes and gradually progressive confusion were noted. In January 1973, vomiting, forther confusion, obnubilation, and a left central facial paresis developed and he was hospitalized. [ncbi.nlm.nih.gov]

  Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances Antibody levels may be low in spinal fluid in cases of Histoplasma meningitis [mayomedicallaboratories.com]

  Symptoms are usually similar to those of acute bacterial meningitis (headache, fever, and stiff neck) but may also include confusion, hearing loss, and double vision. [msdmanuals.com]

• Altered Mental Status

  Headache, stiff neck, fever, nausea and vomiting, photophobia, and altered mental status are potential symptoms of fungal meningitis. Blood and cerebrospinal fluid are cultured and examined to diagnose fungal meningitis. [medicinenet.com]

  Signs and symptoms [ edit ] Symptoms of fungal meningitis are generally similar to those of other types of meningitis, and include: a fever, stiff neck, severe headache, photophobia (sensitivity to light), nausea and vomiting, and altered mental status [en.wikipedia.org]

  mental status. 32 Most patients with aspergillus meningitis present with altered mental status, seizures, or focal neurologic deficits. [ahcmedia.com]

  Top of Page Signs and Symptoms Signs and symptoms of fungal meningitis may include the following: Fever Headache Stiff neck Nausea and vomiting Photophobia (eyes being more sensitive to light) Altered mental status (confusion) Diagnosis If a doctor suspects [cdc.gov]

• Seizure

  Seizures: occur more commonly during the acute stage of the disease. [patient.info]

  The initial seizure activity described was due to fungal meningitis ( C. neoformans is often referred to as neurotropic). [vet.uga.edu]

  Symptoms of histoplasmosis range from none to flu -like symptoms ( fever, dry cough, chest discomfort); severe infections may cause vision problems, mouth ulcers, seizures, encephalopathy, and death. [emedicinehealth.com]

  Cortical vein thrombosis produces hemorrhagic infarction of the cortex, with resultant focal signs and (often) seizures. [dartmouth.edu]

• Intracranial Hemorrhage

  The second patient presented with an intracranial hemorrhage complicated by Staphylococcus epidermidis meningitis caused by an infected intracranial pressure monitor and had a CF titer in serum of 1:8 [ 6 ]. [ncbi.nlm.nih.gov]

  A 27-year-old man with acute myelomonocytic leukemia in remission and repeated intracranial hemorrhages. N Eng J Med 1988;318:427-40. 105. Seres JL, Ono H, Benner EJ. Aspergillosis presenting as spinal cord compression. [neurologyindia.com]

An extensive workup, including EEG, brain MRI and lumbar puncture, revealed possible Creutzfeldt-Jakob disease. Unfortunately, the patient failed to improve and died 12 days after admission. [jhu.pure.elsevier.com]

An extensive workup, including EEG, brain MRI and lumbar puncture, revealed possible Creutzfeldt-Jakob disease. Unfortunately, the patient failed to improve and died 12 days after admission. [ncbi.nlm.nih.gov]

Neurological exam remained normal on subsequent neurology clinic visits, and a sedated lumbar puncture was planned as the next step in his workup. [journals.lww.com]

• Hyponatremia

  Inappropriate antidiuretic hormone (ADH) secretion may result in hyponatremia from water excess and salt loss. Water restriction is usually effective in treating this transient complication. [dartmouth.edu]

  Hyperkalemia, hyponatremia, and eosinophilia are usually present. CT scan shows markedly enlarged adrenals, often with necrosis in the central area ( 160 ). Adrenal insufficiency was a frequent cause of death in earlier years ( 110 ). [cmr.asm.org]

• Helicobacter Pylori

  A fifth patient, who was receiving antibiotics for Helicobacter pylori gastritis, developed fever, altered mental status, rash, and eosinophilia. CSF leukocyte count was 4 cells/µL, the glucose was 55 mg/dL, and the protein was 28 mg/dL. [ncbi.nlm.nih.gov]

Her condition responded to treatment with amphotericin B for 2 weeks followed by itraconazole treatment, 200 mg twice daily. [academic.oup.com]

[…] and Prevention of Influenza 480 AIDS 78 Transmission and Prevention of HIV Infection 489 Primary HIV infection 496 Treatment of Pneumocystis Carinii Pneumonia in AIDS 499 HIV1 and Infections of the Central Nervous System 504 Fever in the HIVinfected [books.google.de]

The optimal treatment for CNS histoplamosis, the period of treatment and the recommendation of suppressive therapy is unknown [6,12]. [scielo.br]

[…] granulamatous diseases What is the epidemiology of Coccidiodes immitus Endemic to arid regions of North America • African-American, Filipino at greatest risk for disseminated disease • Women in third trimester of pregnancy at elevated risk What is the treatment [quizlet.com]

The duration of treatment is dependent upon the causal pathogen and the patient's ability to stave off the infection; for patients with a weaker immune system or diabetes, treatment will often take longer. [2] Prognosis [ edit ] Prognosis depends on the [en.wikipedia.org]

What is the prognosis of histoplasmosis? People with mild symptoms of histoplasmosis usually resolve the disease on their own without treatment. In more severe cases, the prognosis is good for those who receive appropriate treatment. [medicinenet.com]

Provides all the information essential for completing a sign-out report: clinical findings, pathologic findings, diagnosis, treatment, and prognosis. [books.google.es]

[…] and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Methods Patients were classified as cases if there was CNS inflammation (CSF WBC ≥ 5 mm 3 /ml) plus laboratory confirmation of H. capsulatum in CNS samples or from extra-CNS sites with no alternative etiology for CSF pleocytosis. [aspergillus.org.uk]

In 183 short chapters, the book provides the essentials clinicians need on symptoms/signs, diagnostic tests, and neurologic disorders of all etiologies. For this edition, Timothy A. [books.google.de]

BACKGROUND: Chronic meningitis encompasses a heterogeneous group of etiologies. Rarely, histoplasmosis may arise as an isolated neurological syndrome in immunocompetent hosts without evidence of general dissemination. [n.neurology.org]

[…] of infections are asymptomatic Diseases caused by Coccidiodes immitus Cocciodiomycosis Meningitis • Osteomyelitis Describe Cocciodiomycosis Erythema nodosum - Desert bumps • Non-specific to disease; side effect of granulamatous diseases What is the epidemiology [quizlet.com]

The ecology of Cryptococcus neoformans and the epidemiology of cryptococcosis. Rev Infect Dis 1991; 13: 1163-1169. Medline (7) Perfect JR, Granger DL, Durack DT. [aidscience.org]

Previous epidemiological and cost studies of fungal meningitis have largely focused on single pathogens, leading to a poor understanding of the disease in general. [jmm.microbiologyresearch.org]

Nosocomial fungal infections: epidemiology, diagnosis, and treatment. Med Mycol. 2007; 45(4): 321-46. PubMed Saccente M, Woods GL. Clinical and laboratory update on blastomycosis. Clin Microbiol Rev. 2010; 23(2): 367-81. PubMed Tuon FF, Costa SF. [arupconsult.com]

Epidemiologic Risks Histoplasma capsulatum var. capsulatum (Western hemisphere. Missisippi River valley up into Ontario, caves in the Caribbean, Central Mexico, and Mexico. There is also cases in Asia and Africa. [pusware.com]

Useful For Suggests clinical disorders or settings where the test may be helpful Aiding in the diagnosis of Histoplasma meningitis in spinal fluid specimens Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they [mayomedicallaboratories.com]

Prospective study of histoplasmosis in patients infected with human immunodeficiency virus: incidence, risk factors, and pathophysiology. Clin Infect Dis. 1997;24:1195–1203 9. Wheat LJ, Kohler RB, Tewari RP, et al. [journals.lww.com]

[…] profound, can calcify Extrapulmonary findings: Liver and spleen calcifications, adrenals, oral ulcers, bone marrow Differentials: Sarcoidosis and tuberculosis Usual treatment: Itraconazole; amphotericin for severe or diffuse disease Prognosis: Excellent Pathophysiology [emedicine.medscape.com]

[…] of Influenza 480 AIDS 78 Transmission and Prevention of HIV Infection 489 Primary HIV infection 496 Treatment of Pneumocystis Carinii Pneumonia in AIDS 499 HIV1 and Infections of the Central Nervous System 504 Fever in the HIVinfected Patient 516 Prevention [books.google.de]

The lack of humoral and cellular response to histoplasma in CSF may have allowed meningitis to develop, while the cellular response to histoplasma elsewhere prevented development of disseminated histoplasmosis. [ncbi.nlm.nih.gov]