Skip to content PULMONARY HISTOPLASMOSIS CAUSING CARDIAC TAMPONADE Ann-Marie Tantoco, MD*, Ohio State University Wexner Medical Center, Columbus, OH Case Presentation: A 16 year old Liberian male presented with acute chest pain, abdominal pain, nausea [shmabstracts.org]

• Coarctation of the Aorta

  Histoplasma capsulatum: An Unusual Case of Pericardial Effusion and Coarctation of the Aorta. Sansom S, Shah A, Hussain S, Walloch J, Kumar S. Sansom S, et al. J Clin Med Res. 2016 Mar;8(3):254-6. doi: 10.14740/jocmr2455w. Epub 2016 Jan 26. [pubmed.ncbi.nlm.nih.gov]

• Suggestibility

  Neither patient had a past medical history suggestive of acute pericarditis, and the presumptive diagnosis was chronic calcific pericarditis secondary to histoplasmosis. [acpjournals.org]

• Pericardial Calcification

  BILLINGS FT and COUCH OA : Pericardial calcification and histoplasmin sensitivity. Ann. Intern. Med. 42: 654, 1955. LinkGoogle Scholar 2. HURWITZ JK and PASTOR BH : Pericardial calcification associated with histoplasmosis. New Engl. J. [acpjournals.org]

  It may resolve spontaneously or recur; occasionally, it leads to pericardial calcification.1,2 We describe a case of Histoplasma pericarditis in which the infecting organism was isolated from the pericardial fluid. [jamanetwork.com]

  Only one patient had pericardial calcification, and none had constrictive pericarditis. This form of granulomatous pericarditis, unlike that caused by Mycobacterium tuberculosis, appears to carry a good prognosis. [pubmed.ncbi.nlm.nih.gov]

• Pulmonary Calcification

  CHRISTIE A and PETERSON JG : Pulmonary calcifications in negative reactors to tuberculin. Amer. J. Public Health 35: 1131, 1945. CrossrefGoogle Scholar 20. SWEANY HC : Histoplasmosis, Charles C Thomas, Springfield, Illinois, 1960, p. 93. [acpjournals.org]

• Complement Fixing Antibody

  All patients demonstrated a fourfold or greater change in complement-fixing antibody titers. No patient had disseminated disease, and only one required treatment with ampholericin B. [pubmed.ncbi.nlm.nih.gov]

No patient had disseminated disease, and only one required treatment with ampholericin B. The illness ran a protracted course, and in six patients symptomatic pericarditis recurred. Ultimately all recovered. [pubmed.ncbi.nlm.nih.gov]

This form of granulomatous pericarditis, unlike that caused by Mycobacterium tuberculosis, appears to carry a good prognosis. Similar articles The radiological features of Histoplasma pericarditis. Kirchner SG, Heller RM, Sell SH, Altemeier WA 3rd. [pubmed.ncbi.nlm.nih.gov]

RUBIN H, FURCOLOW ML, YATES JL, and BRASHER CS : The course and prognosis of histoplasmosis. Amer. J. Med. 27: 278, 1959. CrossrefMedlineGoogle Scholar 22. [acpjournals.org]