Consequently, it seems necessary to better characterize hMPV infections in adult inpatients: presentation, course profile and risk factors for morbidity and mortality. [clinicaltrials.gov]

The under-2 patients more frequently presented cough, rhinitis, apnoea and difficulty breathing, with statistically significant differences found ( p 0.001); meanwhile those over 2 more frequently presented seizures and fever ( p = 0.005). [elsevier.es]

Children with respiratory infections frequently present to primary care. [ncbi.nlm.nih.gov]

The demographic and clinical data presented in this study improves our understanding of the pathogenesis and clinical burden of hMPV infection in adults. Voir l'article [fondation-merieux.org]

We recommend that you include samples from each age group in your clinical studies and present the data stratified by age (e.g., less than 5, 6- 21, 22-59, and greater than 60 years old) in addition to the overall data summary table. 6.G.v Presentation [fda.gov]

• Unconsciousness

  […] severe pneumonia, i.e. cough or difficulty in breathing plus any one or more of the following: lower chest wall indrawing (severe pneumonia), oxygen saturation of less than 90 % (finger tip pulse oximetry), inability to drink or breast feed, prostrate or unconscious [bmcinfectdis.biomedcentral.com]

• High Fever

  Cough, sore throat, runny nose, and high fever are most common. Wheezing, difficulty breathing (dyspnea), pneumonia, bronchitis, bronchiolitis, conjunctivitis, and inflammation of the middle ear (otitis media) each occur in 10% or more of patients. [medicinenet.com]

• Convulsions

  Some children may also present with otitis media, diarrhoea, vomiting, rash, and febrile convulsion. In adult, HMPV usually causes mild disease characterised by cough, hoarseness, runny nose and sputum production. [chp.gov.hk]

Palivizumab (monoclonal antibody to RSV) is not effective for treatment. [msdmanuals.com]

Supportive treatment for patients varies with the severity of the illness but generally treatment consists of fever reducers, antihistamines, breathing treatments and other means of providing comfort to the patient until the illness resolves. [idph.state.il.us]

To date, no vaccine is available and treatment is supportive. However, ongoing research shows encouraging results. [mendeley.com]

Currently, treatment of hMPV-associated lower respiratory tract infections is mainly symptomatic. [clinicaltrials.gov]

The primary objective is to describe the prognosis. [clinicaltrials.gov]

Human bocaviruses: possible etiologic role in respiratory infection. J Clin Virol 2015; 72: 75-81 28 Daleno C, Greenberg D, Piralla A. [thieme-connect.de]

Can respiratory syncytial virus etiology be diagnosed clinically? A hospital-based case-control study in children under two years of age. Eur J Epidemiol. 2003; 18 431-439 69 Wilkesmannn A, Schildgen O, Eis-Hübinger A. et al. [thieme-connect.com]

Viral etiology of acute respiratory infections among children in Porto Alegre, RS, Brazil. Rev Soc Bras Med Trop. 2002;35(4):283-91. [ Links ] 38. Escobar C, Luchsinger V, de Oliveira DB, Durigon E, Chnaiderman J, Avendaño LF. [scielo.br]

The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice. J Pediatr 1979 ;95: 183 - 190 3. Hall CB, Walsh EE, Schnabel KC, et al. [nejm.org]

The etiologic agents of bronchiolitis include adenovirus, influenza and parainfluenza viruses, and Bordetella pertussis. However, most infections are due to respiratory syncytial virus (RSV) ( 2 ). [ncbi.nlm.nih.gov]

Because human metapneumovirus is a newly recognized pathogen, many clinicians are unfamiliar with the epidemiology, pathogenesis, and clinical signs and symptoms of infection. [pedsinreview.aappublications.org]

Human metapneumovirus infection in Jordanian children: epidemiology and risk factors for severe disease. Pediatr Infect Dis J, 34 (2015), pp. 1335-1341 [9] J.V. Williams, S.J. Tollefson, P.W. Heymann, H.T. Carper, J. Patrie, J.E. Crowe. [elsevier.es]

Animal studies have been conducted but no human studies have been performed. 9 The CDC closely follows hMPV trending to assist with understanding the virus' infection burden and epidemiology. 1 Patient education While awaiting diagnosis and after the [journals.lww.com]

The epidemiology of HMPV in sub-Saharan Africa is poorly described and factors that allow its recurrent epidemics in communities not understood. [bmcinfectdis.biomedcentral.com]

Through serologic testing, the authors demonstrated that this was a newly discovered but not newly emerged virus. 1 Epidemiology. The epidemiology of hMPV has been described using seroprevalence, PCR, and cell culture. [nature.com]

Prevention and Treatment Currently, there is no specific antiviral therapy to treat HMPV and no vaccine to prevent HMPV. Medical care is supportive. [cdc.gov]

Prevention Vaccine is not available at the moment. [chp.gov.hk]

Schweon is an infection prevention consultant in Saylorsburg, Pa. The author has disclosed that he has no financial relationships related to this article. [journals.lww.com]

Prevention of hMPV infection There is no vaccine for available for hMPV. Prevention of hMPV infection depends on good hygienic methods to reduce the spread of the virus. Recommended Reading Falsey AR (October 2008). [quidel.com]