Consequently, it seems necessary to better characterize hMPV infections in adult inpatients: presentation, course profile and risk factors for morbidity and mortality. [clinicaltrials.gov]

The under-2 patients more frequently presented cough, rhinitis, apnoea and difficulty breathing, with statistically significant differences found ( p 0.001); meanwhile those over 2 more frequently presented seizures and fever ( p 0.005). [elsevier.es]

Children with respiratory infections frequently present to primary care. [ncbi.nlm.nih.gov]

We recommend that you include samples from each age group in your clinical studies and present the data stratified by age (e.g., less than 5, 6- 21, 22-59, and greater than 60 years old) in addition to the overall data summary table. 6.G.v Presentation [fda.gov]

The demographic and clinical data presented in this study improves our understanding of the pathogenesis and clinical burden of hMPV infection in adults. Voir l'article [fondation-merieux.org]

• Disability

  Characteristics of human metapneumovirus infection prevailing in hospital wards housing patients with severe disabilities. Jpn J Infect Dis. 2013;66(3):195-200. [ Links ] 27. Boivin G, Abed Y, Pelletier G, Ruel L, Moisan D, Cote S, et al. [scielo.br]

  "Outbreak of human metapneumovirus infection in a severe motor-and-intellectual disabilities ward in Japan". Japanese Journal of Infectious Diseases. 67 (4): 318–321. doi : 10.7883/yoken.67.318. ISSN 1884-2836. [en.wikipedia.org]

• Localized Pain

  This response causes the classic symptoms of a "cold," including local pain, low-grade fever, cough, runny nose, headache and sore throat. [lung.org]

• Shivering

  HMPV infections were associated with cough, fever/shivers and pneumonia, respectively. [journals.plos.org]

• Hoarseness

  More severe illness, with wheezing, difficulty breathing, hoarseness, cough, pneumonia, and in adults, aggravation of asthma, also has been reported. [idph.state.il.us]

  In adult, HMPV usually causes mild disease characterised by cough, hoarseness, runny nose and sputum production. [chp.gov.hk]

  Recognizing hMPV Infants and young children infected with hMPV demonstrate signs and symptoms similar to RSV: cough, wheezing, myalgia, dyspnea, tachypnea, rhinorrhea, and pyrexia. 8 In adults, signs and symptoms include nasal congestion, cough, rhinorrhea, hoarseness [journals.lww.com]

  Laryngotracheobronchitis (croup) was defined as an acute lower respiratory tract infection characterized by hoarseness, cough, and stridor. [nejm.org]

• Decreased Breath Sounds

  Pneumonia was defined as dyspnea in a patient with focal rales or decreased breath sounds and the presence of a focal infiltrate on the chest radiograph. [nejm.org]

• Stridor

  Laryngotracheobronchitis (croup) was defined as an acute lower respiratory tract infection characterized by hoarseness, cough, and stridor. [nejm.org]

• Convulsions

  Some children may also present with otitis media, diarrhoea, vomiting, rash, and febrile convulsion. In adult, HMPV usually causes mild disease characterised by cough, hoarseness, runny nose and sputum production. [chp.gov.hk]

• Stroke

  These 6 averaged 85 years of age, 4 had underlying COPD, and 1 each had coronary artery disease and prior stroke. They died between 10 and 30 days after admission, generally of respiratory failure. [jamanetwork.com]

• Lethargy

  These include pyrexia and moist cough (12), sore throat (6), myalgia (5) and lethargy (4). This clinical picture is not dissimilar to influenza in the elderly. [www1.health.gov.au]

Palivizumab (monoclonal antibody to RSV) is not effective for treatment. [msdmanuals.com]

Supportive treatment for patients varies with the severity of the illness but generally treatment consists of fever reducers, antihistamines, breathing treatments and other means of providing comfort to the patient until the illness resolves. [idph.state.il.us]

To date, no vaccine is available and treatment is supportive. However, ongoing research shows encouraging results. [mendeley.com]

Currently, treatment of hMPV-associated lower respiratory tract infections is mainly symptomatic. [clinicaltrials.gov]

The primary objective is to describe the prognosis. [clinicaltrials.gov]

Can respiratory syncytial virus etiology be diagnosed clinically? A hospital-based case-control study in children under two years of age. Eur J Epidemiol. 2003; 18 431-439 69 Wilkesmannn A, Schildgen O, Eis-Hübinger A. et al. [thieme-connect.com]

Viral etiology of acute respiratory infections among children in Porto Alegre, RS, Brazil. Rev Soc Bras Med Trop. 2002;35(4):283-91. [ Links ] 38. Escobar C, Luchsinger V, de Oliveira DB, Durigon E, Chnaiderman J, Avendaño LF. [scielo.br]

The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice. J Pediatr 1979 ;95: 183 - 190 3. Hall CB, Walsh EE, Schnabel KC, et al. [nejm.org]

Human bocaviruses: possible etiologic role in respiratory infection. J Clin Virol 2015; 72: 75-81 28 Daleno C, Greenberg D, Piralla A. [thieme-connect.de]

The etiologic agents of bronchiolitis include adenovirus, influenza and parainfluenza viruses, and Bordetella pertussis. However, most infections are due to respiratory syncytial virus (RSV) ( 2 ). [ncbi.nlm.nih.gov]

Because human metapneumovirus is a newly recognized pathogen, many clinicians are unfamiliar with the epidemiology, pathogenesis, and clinical signs and symptoms of infection. [pedsinreview.aappublications.org]

Human metapneumovirus infection in Jordanian children: epidemiology and risk factors for severe disease. Pediatr Infect Dis J, 34 (2015), pp. 1335-1341 [9] J.V. Williams, S.J. Tollefson, P.W. Heymann, H.T. Carper, J. Patrie, J.E. Crowe. [elsevier.es]

Animal studies have been conducted but no human studies have been performed. 9 The CDC closely follows hMPV trending to assist with understanding the virus' infection burden and epidemiology. 1 Patient education While awaiting diagnosis and after the [journals.lww.com]

Through serologic testing, the authors demonstrated that this was a newly discovered but not newly emerged virus. 1 Epidemiology. The epidemiology of hMPV has been described using seroprevalence, PCR, and cell culture. [nature.com]

The etiologic and epidemiologic spectrum of bronchiolitis in pediatric practice. J Pediatr 1979 ;95: 183 - 190 3. Hall CB, Walsh EE, Schnabel KC, et al. [nejm.org]

Prevention Vaccine is not available at the moment. [chp.gov.hk]

Schweon is an infection prevention consultant in Saylorsburg, Pa. The author has disclosed that he has no financial relationships related to this article. [journals.lww.com]

Prevention and Treatment Currently, there is no specific antiviral therapy to treat HMPV and no vaccine to prevent HMPV. Medical care is supportive. [cdc.gov]