By the age of 12 years, he became mute and wheelchair-bound and began to have attacks of tonic movements of the upper limbs with rolling up of both eyes. A year later, Kambouris et al. (2000) presented further data on the same family. [cags.org.ae]

Immobility Destruction of the basal ganglia with loss of movement control, incoordination and postural disturbances leaves patients with advanced Huntington's disease wheelchair-bound. [livestrong.com]

Hirano T...Taira T 2010 21 Fatty liver is independently associated with alterations in circulating HDL2 and HDL3 subfractions. ( 18000185 ) Kantartzis K...Stefan N 2008 22 Serum lecithin: cholesterol acyltransferase activity, HDL2 and HDL3 composition in hypertensive [malacards.org]

Journal of human hypertension. 2007 Sep;21(9):717. He FJ, Nowson CA, MacGregor GA. Fruit and vegetable consumption and stroke: meta-analysis of cohort studies. The Lancet. 2006 Jan 28;367(9507):320-6. [hsph.harvard.edu]

Aßmann Arteriosclerosis, thrombosis, and vascular… 1998 We demonstrate that physiological concentrations of HDL3 inhibit the thrombin-induced platelet fibrinogen binding and aggregation… (More) [semanticscholar.org]

23404243 ) Bulum T...Duvnjak L 2013 14 Validation of a novel homogeneous assay for of HDL3-C measurement. ( 23891742 ) Ashmaig ME...Warnick GR 2013 15 High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis [malacards.org]

[…] of it sponsored by the U.S. government – and mounting anecdotal accounts from patients and physicians highlight CBD’s potential as a treatment for a wide range of maladies, including (but not limited to): Autoimmune diseases (inflammation, rheumatoid arthritis [projectcbd.org]

They were often crippled with arthritis and joint deformity by their teens and had to attend special schools for disabled people. [who.int]

When she was nine years she became totally mute and incontinent, walked only with help, and needed assistance in feeding. She had poor facial expressions, but full eye movements. [cags.org.ae]

Loss of bladder and bowel control leads to urinary and fecal incontinence. [livestrong.com]

John’s father did the same for Cindy in his home for four years until she became incontinent and unable to walk and eat without assistance. [digitaljournal.com]

Weight loss, sleep problems, and incontinence are common signs of advanced HD. Juvenile HD occurs when someone develops symptoms in the first two decades of life; this occurs in about 5 – 10% of all HD cases. [encyclopedia.com]

He was in the hospital because of kidney failure, so we went to go see him. This was before he moved to his full-time care and wasn’t eating properly. “He didn’t like the food” was his excuse, apparently missing my mom's cooking. (Don’t we all!) [elitedaily.com]

( 25230879 ) Rosenblat M...Aviram M 2014 12 α-Tocopherol induces proatherogenic changes to HDL2 & HDL3: an in vitro and ex vivo investigation. ( 23287638 ) Wade L...McEneny J 2013 13 Lower levels of total HDL and HDL3 cholesterol are associated with albuminuria [malacards.org]

Markers, and Other Factors in a Japanese Population. ( 26686740 ) Moriyama K...Takahashi E 2016 8 Statin action enriches HDL3 in polyunsaturated phospholipids and plasmalogens and reduces LDL-derived phospholipid hydroperoxides in atherogenic mixed dyslipidemia [malacards.org]

Norata GD...Eriksson P 2004 35 Purification and measurement of HDL3-binding proteins in human peripheral blood mononuclear cells. ( 12956441 ) Hidaka H...Katsuyama T 2003 36 Cathepsins F and S block HDL3-induced cholesterol efflux from macrophage foam [malacards.org]