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Hyoscyamus Niger Poisoning

Black Henbane Poisoning


Presentation

  • […] information on all major drugs of the time, including opium, cocaine, heroin, cannabis, peyote, fly agaric, henbane, datura, alcohol, kava, betel, coffee, tea, cocoa, and tobacco • A book credited with starting an era of ethnobotany that continues to the present[books.google.com]
  • With criminal homicide by poisoning making up a small percentage of known crimes, the danger of insufficient scholarly attention is present. Dr Michael Farrell makes a significant contribution to ensure against this potential.[books.google.com]
  • Hyoscyamus niger Famiglia:Solanaceae Distribuzione: Ampiamente diffusa in tutta l’America del Nord, in Europa è presente fino alla Scandinavia, in Italia è presente quasi dovunque, assente in Piemonte e nella Val Padana, in Sardegna è presente su tutto[flickr.com]
  • Activated charcoal can bind tropane alkaloids and may be administered if patients present within 1-2 hours of ingestion and bowel sounds are present.[calpoison.org]
  • Maine present Massachusetts present New Hampshire present Rhode Island absent Vermont present Conservation Status Exact status definitions can vary from state to state.[gobotany.newenglandwild.org]
Fever
  • Seite 31 - ... and inflammation, especially of the throat and has been known to cure ague (burning fever). Boiling the inner bark in vinegar produces a useful external wash for lice and for skin problems such as scabies and scabs.[books.google.com]
  • FEVER AND CHILL - Hyoscyamus Niger Fever and chill Night In bed Periodic, recurring; every fourth day Continued fever in brain (cerebral) dazed from fever in complete daze Stages of chill, heat and sweat; chill followed by heat For more, click heading[abchomeopathy.com]
  • Fever : Its fevers are low forms of fever, the continued fever and the typhoid. Modalities:- Worse : - At night, During menses, Mental activity, Jealousy, unhappy love, When lying down Better Stooping.[planethomeopathy.com]
  • Important Characteristic Features Fever (typhoid): Hyoscyamus is very useful in typhoid fever. In the early stage of the disease, the delirium and later, symptoms of cerebral paralysis may call for Hyoscyamus.[homeopathicmedicine.info]
  • Now let me speak of the fevers of Hyoscyamus. I have already given you the symptoms which would indicate the drug in typhoid fever. We have to see how we may apply it in the treatment of fevers with skin symptoms, as scarlatina.[vithoulkas.com]
Pathologist
  • The work is very well referenced, and provides critical information for law enforcement, forensic pathologists, and others, that could be dealing with the criminal poisoner." John H.[books.google.com]
Tachycardia
  • Acute poisoning Euphoria Temporal & spatial disorientation with intensification of sensation & increased clarity of perception Hallucinations, sedation, dysphoria Acute toxic psychosis Tachycardia, palpitations, hypotension Stimulation of appetite 12.[slideshare.net]
  • Nicotiana spp (tobacco) ingestion, inhalation or transdermal exposure is possible nicotinic syndrome: GI symptoms, sweating, tachycardia, hypotension, tremor, seizures Psychotropic alkaloids, e.g.[lifeinthefastlane.com]
  • Dry mouth, tachycardia, decreased bowel sounds and agitation are all characteristic of both syndromes.[calpoison.org]
  • Symptoms of Henbane poisoning include a dry mouth, thirst, difficulty in swallowing and speaking, warm flushed skin, dilated pupils, blurred vision and photophobia, vomiting, urinary retention, tachycardia, pyrexia, drowsiness, slurred speech, hyperreflexia[jeremybartlett.co.uk]
  • Overdosage (which is close to the therapeutic dose) causes dry mouth, dysphagia, pupil dilation, tachycardia, restlessness, hallucinations, delirium and coma. Children have been poisoned by eating the seeds.[purplesage.org.uk]
Flushing
  • His examination was significant for dry mucus membranes and his skin was warm and flushed. On neurologic exam, he was awake, but was confused, agitated and answering “I am Batman” to all questions.[calpoison.org]
  • Symptoms of Henbane poisoning include a dry mouth, thirst, difficulty in swallowing and speaking, warm flushed skin, dilated pupils, blurred vision and photophobia, vomiting, urinary retention, tachycardia, pyrexia, drowsiness, slurred speech, hyperreflexia[jeremybartlett.co.uk]
  • They produce the same dryness of the throat, flushing of the face, dilatation of the pupils, quickening of the respiratory and heart action, illusions, hallucinations and delirium.[henriettes-herb.com]
  • Face: Flushed and dark red, bloated and excited face, dryness of the mouth. Dry tongue loaded with a brownish coating. Throat: Constriction of throat with inability to swallow, especially fluids and liquids.[homeopathicmedicine.info]
  • Causes dry mouth, thirst, difficulty in swallowing and speaking, warm flushed skin, dilated pupils, blurred vision and photophobia, vomiting, urinary retention, tachycardia, pyrexia, drowsiness, slurred speech, hyperreflexia, auditory, visual or tactile[thepoisongarden.co.uk]
Blurred Vision
  • [Case Reports] VL Vnitr Lek 2000; 46(11):808-10 Stefánek J, Dufincová J, … Holmes S The authors describe the case of a 27-year-old man who was examined on account of vertigo and blurred vision.[unboundmedicine.com]
  • Blurred vision and photophobia may be due to mydraisis and paralysis of accomodation. Seizures, paralysis, respiratory depression, and coma may ensue in severe cases.[calpoison.org]
  • Symptoms of Henbane poisoning include a dry mouth, thirst, difficulty in swallowing and speaking, warm flushed skin, dilated pupils, blurred vision and photophobia, vomiting, urinary retention, tachycardia, pyrexia, drowsiness, slurred speech, hyperreflexia[jeremybartlett.co.uk]
  • Causes dry mouth, thirst, difficulty in swallowing and speaking, warm flushed skin, dilated pupils, blurred vision and photophobia, vomiting, urinary retention, tachycardia, pyrexia, drowsiness, slurred speech, hyperreflexia, auditory, visual or tactile[thepoisongarden.co.uk]
Diplopia
  • Eyes: open, staring; downcast, dull, fixed; pupils dilated, sparkling, fixed; strabismus; spasmodic closing of lids; vision double, diplopia, objects have coloured borders.[qjure.com]
  • Diplopia. Objects have colored borders. Mouth.-- Tongue dry, red, cracked, stiff and immovable, protruded with difficulty; speech impaired. Foams at mouth. Teeth covered with sordes. Lower jaw drops. Throat.-- Stinging dryness. Constriction.[homeoint.org]
  • EYES - Hyoscyamus Niger Eyes Pupils dilated, sparkling, fixed Eyes open, but does not pay attention; downcast and dull, fixed Strabismus Spasmodic closing of lids Diplopia Objects have colored borders.[abchomeopathy.com]
Confusion
  • In the objective case-history there was mild confusion, in the physical examination broad... New Search Next[unboundmedicine.com]
  • […] thirst, difficulty in swallowing and speaking, warm flushed skin, dilated pupils, blurred vision and photophobia, vomiting, urinary retention, tachycardia, pyrexia, drowsiness, slurred speech, hyperreflexia, auditory, visual or tactile hallucinations, confusion[jeremybartlett.co.uk]
  • Confusion, sopor, deep stupor, stupefaction, coma vigil, convulsions, wants to escape, run away. Sad, sobbing, cries, in sleep, in children, suicidal. Nervous agitation; tremulous, weak, restless, twitching of tendons.[qjure.com]
  • .-- Feels light and confused. Vertigo as if intoxicated. Brain feels loose, fluctuating. Inflammation of brain, with unconsciousness; head is shaken to and fro. Eyes.-- Pupils dilated, sparkling, fixed.[homeoint.org]
  • HEAD - Hyoscyamus Niger Head Feels light and confused Brain feels loose, fluctuating Inflammation of brain, with unconsciousness; head is shaken to and fro. Headache Pain, headache; in forehead For more, click heading above.[abchomeopathy.com]
Stupor
  • As the mania advances he seems to lie in a sort of stupor and yet it is not a real stupor, because the slightest noise rouses him into all these forms of violent mania. Every little impression causes excitement of the sensorium.[vithoulkas.com]
  • -When spoken to answers properly but stupor and delirium return immediately. -Delirium-attempts to run away. Restless, jumps out of bed, wants to escape. -talks of business, complaints of imaginary wrongs.[cure4incurables.com]
  • This type of poisoning, which can take place even after ingesting a small amount of plant or seed matter, can have symptoms such as increased salivation, headache, nausea, convulsions, hallucinations, stupor, coma and death.[worldseedsupply.com]
  • Confusion, sopor, deep stupor, stupefaction, coma vigil, convulsions, wants to escape, run away. Sad, sobbing, cries, in sleep, in children, suicidal. Nervous agitation; tremulous, weak, restless, twitching of tendons.[qjure.com]
  • Low, muttering speech; constant carphologia, deep stupor . Head.-- Feels light and confused. Vertigo as if intoxicated. Brain feels loose, fluctuating. Inflammation of brain, with unconsciousness; head is shaken to and fro.[homeoint.org]

Treatment

  • Although it is commonly self-limited and can be corrected with close observation and supportive treatments, it should be kept in mind that the prolongation of QT interval can accompany the symptoms of poisoning with this plant (Tab. 1, Fig. 3, Ref. 19[unboundmedicine.com]
  • Its sedative and antispasmodic effect makes it a valuable treatment for the symptoms of Parkinson's disease, relieving tremor and rigidity during the early stages of the disease.[naturalmedicinalherbs.net]
  • Treatment: Stomach wash, activated charcoal Symptomatic Psychotherapy Medicolegal importance Rich man’s drug Champagne drug Body packing 20.[slideshare.net]
  • The plant is used internally in the treatment of asthma, whooping cough, motion sickness, Meniere's syndrome, tremor in senility or paralysis and as a pre-operative medication.[montana.plant-life.org]

Prognosis

  • Prognosis The outcome of poisoning varies from complete recovery to death, and depends on the type and amount of the poison, the health of the victim, and the speed with which medical care is obtained.[medical-dictionary.thefreedictionary.com]

Epidemiology

  • Epidemiology Frequency United States Incidence is sporadic, with clusters of poisoning cases, mostly among adolescents using plants for their hallucinogenic effects.[emedicine.medscape.com]
  • Epidemiology The 2004 annual report of the American Association of Poison Control Centers listed 1058 cases of exposure to anticholinergic plants, 456 of these being intentional.[calpoison.org]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Tropane alkaloids competitively inhibit postsynaptic muscarinic acetylcholine receptors producing the classic anticholinergic syndrome.[calpoison.org]
  • Pathophysiology Toxicity from plants containing tropane alkaloids manifests as classic anticholinergic poisoning.[emedicine.medscape.com]

Prevention

  • The author of this important and timely work explores the theoretical bases for understanding homicidal poisoning, the nature of poisons used in homicidal cases, the characteristics of poisoners and their victims, and techniques for detection and prevention[books.google.com]
  • Wear gloves and protective clothing when handling the plants to prevent rashes. Cultural Control Good vegetative cover considerably reduces the chance of infestation.[nwcb.wa.gov]
  • Prevention Most accidental poisonings are preventable. The number of deaths of children from poisoning has declined from about 450 per year in the 1960s to about 50 each year in the 1990s.[medical-dictionary.thefreedictionary.com]
  • It is as if some diabolical force took possession of the brain and prevented its functions. It causes a perfect picture of mania of a quarrelsome and obscene character . Inclined to be unseemly and immodest in acts, gestures and expressions.[homeoint.org]
  • The alkaloid hyoscine is used very widely as a pre-operative medication and a travel sickness preventative. Because of the danger of poisoning, this herb is used primarily for external applications.[purplesage.org.uk]

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