Presentation
We present a case of pneumatosis cystoides intestinalis in a patient with granulomatosis with polyangiitis that was treated successfully with hyperbaric oxygen. [ncbi.nlm.nih.gov]
Entire Body System
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Noncompliance
After emptying nodular abscess, the patient was noncompliant for further surgery. Therefore, it was suggested the association between HBOT and antibiotic therapy. [ncbi.nlm.nih.gov]
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Turkish
A 25-year-old Turkish man with a history of sickle cell disease developed sudden painless loss of vision in the left eye and was hospitalized for diagnosis and treatment. [ncbi.nlm.nih.gov]
Gastrointestinal
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Intestinal Perforation
He underwent urgent exploratory laparotomy, which led to a diagnosis of pneumatosis cystoides intestinalis without intestinal perforation or necrosis. [ncbi.nlm.nih.gov]
Musculoskeletal
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Neck Pain
Nine months later, he presented with neck pain, cough with mucopurulent sputum, and fever. A PET-CT scan revealed a fissure in the posterior wall of the left upper trachea. [ncbi.nlm.nih.gov]
Skin
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Chronic Dermatitis
However, radiation exposure induces acute or chronic dermatitis, depending on the radiation dose, interval, tissue volume, or irradiated area of the body. [ncbi.nlm.nih.gov]
Neurologic
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Seizure
area to explore whether the patients who experienced seizures in the hyperbaric chamber had other medical comorbidities or were on medications which lowered their seizure threshold, thereby contributing to oxygen toxicity seizures. [ncbi.nlm.nih.gov]
Oxygen toxicity seizures The high level of oxygen in the blood that occurs during HBO treatments can be toxic to the central nervous system and can result in seizure activity. [uihc.org]
Workup
Proctoscopy
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Rectal Ulceration
In the present study, we assessed the efficacy of hyperbaric oxygen therapy in five patients with radiation-induced rectal ulcers. [ncbi.nlm.nih.gov]
Treatment
We hypothesized that early treatment response could predict treatment failure. [ncbi.nlm.nih.gov]
Prognosis
The primary outcomes in studies I and II will be endothelial biomarker levels after HBOT, and in study III suPAR levels as a marker of disease prognosis and severity. [ncbi.nlm.nih.gov]
Fetterman BL, Saunders JE, Luxford WM (1996) Prognosis and treatment of sudden sensorineural hearing loss.Am J Otol 17: 529-536. [hsj.gr]
Long-term prognosis of diabetic foot patients and their limbs: amputation and death over the course of a decade. Diabetes Care 2012;35:2021–7. 19. Fedorko L, Bowen JM, Jones W, et al. [journals.lww.com]
Etiology
Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by an ulcerative skin condition and confirmed through a diagnosis of exclusion. [ncbi.nlm.nih.gov]
The etiology of PG remains poorly understood, but a predominantly immunological pathogenesis involving neutrophil dysfunction seems most likely. [o-wm.com]
As far as it concerns the research data of the patients’ general history, diseases such as hypertension, hyperlipidemia, diabetes mellitus and hypothyroidism did not seem to affect the etiology of the disease. [hsj.gr]
Epidemiology
Author information 1 Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada. [email protected] 2 Programs for Assessment of Technology in Health (PATH), Centre for Evaluation of [ncbi.nlm.nih.gov]
Journal of Clinical Epidemiology. 2014;67:65. Dauwe PB, et al. Does hyperbaric oxygen therapy work in facilitating acute wound healing: A systematic review. Plastic & Reconstructive Surgery Journal. 2014;133:208e. [docdoc.com.sg]
Journal of Clinical Epidemiology. 2014;67:65. Rajagopalan G, et al. Is HOT a cool treatment for type 1 diabetes? Diabetes. 2012;61:1664. Hyperbaric oxygen therapy: Don't be misled. U.S. Food and Drug Administration. . Accessed Aug. 20, 2014. [mayoclinic.org]
Pathophysiology
More fundamental research is also needed to clarify the pathophysiology of ORN, which in turn would help identify appropriate treatments. [ncbi.nlm.nih.gov]
Osteoradionecrosis: a new concept of its pathophysiology. J Oral Maxillofac Surg. 1983;41(5):283-8. Reuther T, Schuster T, Mende U, Kübler A. [jcda.ca]
Two other pathophysiological factors may be considered in accounting for the proposed clinical presentation of a cerebral oxygen embolism. [pediatrics.aappublications.org]
Prevention
To date, there is no evidence to support the use of hyperbaric oxygen in the prevention of necrosis of airway reconstructions in humans. [ncbi.nlm.nih.gov]
Cellular and biochemical benefits of hyperbaric oxygen Promotes angiogenesis and wound healing Kills certain anaerobes Prevents growth of species such as Pseudomonas Prevents production of clostridial alpha toxin Restores neutrophil mediated bacterial [bmj.com]
Special measures are required to prevent and treat it, and hyperbaric oxygen therapy is often mentioned in this context. [jcda.ca]