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Hyperbaric Oxygen Therapy

Hyperbaric Oxygenation


Presentation

  • We present a case of pneumatosis cystoides intestinalis in a patient with granulomatosis with polyangiitis that was treated successfully with hyperbaric oxygen.[ncbi.nlm.nih.gov]
  • Thus, HBOT may present an option for the management of PSH in addition to pharmacologic therapy. Potential mechanisms for these effects are discussed.[ncbi.nlm.nih.gov]
  • We present a case of branch retinal artery occlusion (BRAO) in a healthy 20-year-old woman with no history of ocular or systemic diseases or drug use.[ncbi.nlm.nih.gov]
  • This study aimed to present a clinical report of an irradiated oncologic patient who underwent hyperbaric oxygen therapy to be rehabilitated with implant-supported prosthesis.[ncbi.nlm.nih.gov]
  • Case 1: a 61-year-old female, presented with CRAO in her left eye(OS). She was submitted to eight sessions of HBOT(2.4atmosphere absolute (ATA)).[ncbi.nlm.nih.gov]
Turkish
  • A 25-year-old Turkish man with a history of sickle cell disease developed sudden painless loss of vision in the left eye and was hospitalized for diagnosis and treatment.[ncbi.nlm.nih.gov]
Osteopenia
  • It is characterized by transient osteopenia and by gradually increasing pain associated with a limitation of the range of motion of the hip. Bone marrow oedema is a typical but nonspecific finding in TOH.[ncbi.nlm.nih.gov]
Chronic Dermatitis
  • However, radiation exposure induces acute or chronic dermatitis, depending on the radiation dose, interval, tissue volume, or irradiated area of the body.[ncbi.nlm.nih.gov]
Angioedema
  • Despite intensive care treatment, face angioedema persisted for several days. On the basis of history, radioallergosorbent test (RAST) and prick tests, latex was assumed to be responsible for the anaphylactic reaction.[ncbi.nlm.nih.gov]
Quickening
  • There is insufficient evidence to support or reject the use of HBOT to quicken healing or to treat the established non-union of fractures.[ncbi.nlm.nih.gov]
Stereotyped Behavior
  • Several studies show that diminished blood flow to these areas correlates with many of the clinical features associated with autism including repetitive, self-stimulatory and stereotypical behaviors, and impairments in communication, sensory perception[healing-arts.org]
Microscopic Hematuria
  • Macroscopic hematuria resolved within a week, and microscopic hematuria was no longer detectable within 2 weeks. Hematuria did not recur after 11 sessions of HBO therapy, and no significant side effects were observed during or after treatment.[ncbi.nlm.nih.gov]
Seizure
  • ., area to explore whether the patients who experienced seizures in the hyperbaric chamber had other medical comorbidities or were on medications which lowered their seizure threshold, thereby contributing to oxygen toxicity seizures.[ncbi.nlm.nih.gov]
  • Various reports show the occurrence of self-limiting seizures after carbon monoxide poisoning and as a consequence of hyperbaric oxygen therapy. Contrary to the seizures, status epilepticus has been rarely observed in these conditions.[ncbi.nlm.nih.gov]
  • A seizure during decompression was observed in 2/59 participants (2/419 sessions).[ncbi.nlm.nih.gov]
  • In this analysis, events are defined as otic/sinus barotrauma, confinement anxiety, hypoglycemia, oxygen toxicity, pneumothorax, seizure, and shortness of breath.[ncbi.nlm.nih.gov]

Workup

Hypercapnia
  • Each patient had risk factors for seizures, including hypercapnia secondary to chronic obstructive pulmonary disease, narcotic withdrawal, alcohol dependence, and antidepressant, tramadol or cephalosporin/ceftriaxone use.[ncbi.nlm.nih.gov]

Treatment

  • Group A was treated with conventional treatment plus HBOT. Group B was treated with conventional treatment only. Data collection included age, gender, clinical symptoms, pure-tone audiometry results and treatment outcome.[ncbi.nlm.nih.gov]
  • Full details of treatment costs in AUD were obtained (AUD 1.0, approx. EUR 0.6). A detailed patient diary accurately cross-referenced the consultations, investigations, admissions and treatment.[ncbi.nlm.nih.gov]
  • We hypothesized that early treatment response could predict treatment failure.[ncbi.nlm.nih.gov]
  • Abstract Although radiation therapy is a common treatment for head and neck cancer, osteoradionecrosis (ORN) represents a major complication during or after treatment.[ncbi.nlm.nih.gov]
  • There was one case of transient eustachian tube dysfunction and three cases of reversible exudative otitis media as a consequence of HBO treatment. HBO is a potent treatment for PBS/IC patients resistant to conventional therapy.[ncbi.nlm.nih.gov]

Prognosis

  • The primary outcomes in studies I and II will be endothelial biomarker levels after HBOT, and in study III suPAR levels as a marker of disease prognosis and severity.[ncbi.nlm.nih.gov]
  • OBJECTIVE: This study evaluated the prognosis of idiopathic sudden sensorineural hearing loss when treated with hyperbaric oxygen therapy and intravenous steroids.[ncbi.nlm.nih.gov]
  • According to multivariate analysis, later onset of HBOT and higher initial hearing threshold were associated with a poor prognosis in ISSNHL patients treated with HBOT.[ncbi.nlm.nih.gov]
  • Fetterman BL, Saunders JE, Luxford WM (1996) Prognosis and treatment of sudden sensorineural hearing loss.Am J Otol 17: 529-536.[hsj.gr]
  • Long-term prognosis of diabetic foot patients and their limbs: amputation and death over the course of a decade. Diabetes Care 2012;35:2021–7. 19. Fedorko L, Bowen JM, Jones W, et al.[journals.lww.com]

Etiology

  • Pyoderma gangrenosum (PG) is a neutrophilic dermatosis of unknown etiology characterized by an ulcerative skin condition and confirmed through a diagnosis of exclusion.[ncbi.nlm.nih.gov]
  • There is no confirmed strategy for treating painful bladder syndrome/interstitial cystitis (PBS/IC) with unclear etiology.[ncbi.nlm.nih.gov]
  • The etiology of PG remains poorly understood, but a predominantly immunological pathogenesis involving neutrophil dysfunction seems most likely.[o-wm.com]
  • As far as it concerns the research data of the patients’ general history, diseases such as hypertension, hyperlipidemia, diabetes mellitus and hypothyroidism did not seem to affect the etiology of the disease.[hsj.gr]
  • References 1 Incidence, outcomes, and cost of foot ulcers in patients with diabetes , Diabetes Care , 1999 , vol. 22 (pg. 382 - 7 ) 2 Amputation and mortality in new-onset diabetic foot ulcers stratified by etiology , Diabetes Care , 2003 , vol. 26 (pg[academic.oup.com]

Epidemiology

  • Author information 1 Department of Clinical Epidemiology and Biostatistics, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4L8, Canada. lig28@mcmaster.ca. 2 Programs for Assessment of Technology in Health (PATH), Centre for Evaluation of[ncbi.nlm.nih.gov]
  • BACKGROUND: To evaluate the epidemiology of patients who require mechanical ventilation during hyperbaric oxygen therapy.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • The exact pathophysiology underlying seizures and status epilepticus associated with carbon monoxide poisoning and hyperbaric oxygen therapy is not really clear, and some elements appear to be common to both conditions.[ncbi.nlm.nih.gov]
  • More fundamental research is also needed to clarify the pathophysiology of ORN, which in turn would help identify appropriate treatments.[ncbi.nlm.nih.gov]
  • Osteoradionecrosis: a new concept of its pathophysiology. J Oral Maxillofac Surg. 1983;41(5):283-8 . Reuther T, Schuster T, Mende U, Kübler A.[jcda.ca]
  • Two other pathophysiological factors may be considered in accounting for the proposed clinical presentation of a cerebral oxygen embolism.[pediatrics.aappublications.org]
  • Acute and impaired wound healing: pathophysiology and current methods for drug delivery, part 1: normal and chronic wounds : biology, causes, and approaches to care. Adv Skin Wound Care 2012;25:304–14. 9. Reinke JM, Sorg H.[journals.lww.com]

Prevention

  • To date, there is no evidence to support the use of hyperbaric oxygen in the prevention of necrosis of airway reconstructions in humans.[ncbi.nlm.nih.gov]
  • The widespread use of such therapy for the prevention and treatment of ORN appears to be based mainly on personal beliefs and experience, as no consensus exists in the scientific literature about its efficacy.[ncbi.nlm.nih.gov]
  • Cellular and biochemical benefits of hyperbaric oxygen Promotes angiogenesis and wound healing Kills certain anaerobes Prevents growth of species such as Pseudomonas Prevents production of clostridial alpha toxin Restores neutrophil mediated bacterial[bmj.com]
  • It also is used to prevent the occurrence of osteoradionecrosis in the irradiated patient when dental surgery is indicated.[ncbi.nlm.nih.gov]
  • After diagnosis of CUA, patient was treated with HBO therapy for successive three weeks with a session per day, on the basis of secondary infection prevention.[ncbi.nlm.nih.gov]

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