Severe renal impairment was present and regressed as the patient improved. The pathogenesis and treatment of vitamin D intoxication is discussed. Received January 22, 1957. Accepted July 25, 1957. [pediatrics.aappublications.org]

Abstract We present two cases of hypercalcemic nephropathy associated with primary hyperparathyroidism. [jstage.jst.go.jp]

We present two cases of hypercalcemic nephropathy associated with primary hyperparathyroidism. Case 1 is a 37-year-old man who had repeated bone fractures and recurrent ureteral stones, which led to the diagnosis of primary hyperparathyroidism. [ndif.org]

The renal biopsy specimen for patient 1 exhibited calcium deposits present in the glomerular capillary basement membranes, where they were associated with segmental sclerosing lesions (21% of glomeruli). [ncbi.nlm.nih.gov]

Improve your interpretation of presenting symptoms with 39 new topics in the Differential Diagnosis section, and optimize patient care with 12 new tables in the Clinical Practice Guidelines section. [books.google.com]

• Splenomegaly

  hilary lymph node uptake on Computed tomography (CT) scan of this chest, elevated serum ACE level, hypercalcemia (12.3 mg/dL), splenomegaly, retinal degeneration, nonischemic cardiomyophathy with hypertrophy on echocardiography, no pathognomonic skin [peertechz.com]

• Polydipsia

  There are other pathological entities which give rise to polydipsia and polyuria. [fluoridealert.org]

  These include renal colic, polyuria and polydipsia: Renal colic is usually caused by pre-existing nephrolithiasis, as may occur in patients with chronic hypercalciuria. [en.wikipedia.org]

  Hypercalcaemia: polyuria and polydipsia, nausea and vomiting. May cause hypertension. [patient.info]

  Results There were six girls and three boys with clinical symptoms of polyuria, polydipsia, and less frequently, urinary tract infections and lithiasis. All had hypomagnesemia, hypercalciuria and nephrocalcinosis. [analesdepediatria.org]

  Polyuria in sarcoidosis may reflect central diabetes in sipidus (ie, lack of antidiuretic hormone) or primary polydipsia due to granulomatous infiltration of the hypothalamus [27]. [peertechz.com]

• Nocturia

  Nocturia, polyuria, and polydipsia from reduced urinary concentrating capacity (i.e. nephrogenic diabetes insipidus) as can be seen in hypercalcemia, medullary nephrocalcinosis of any cause, or in children with Bartter syndrome in whom essential tubular [en.wikipedia.org]

  Hx: Look for pre-renal causes: Decreased cardiac output signs & symptoms (lightheadedness,SOB, PND, orthopnea etc) Bleeding GI fluid loss Abnormal polyuria Hx: Obstructive / Post Renal: Nocturia / frequency / hesitancy or decreased urinary stream Dysuria [canadiem.org]

[…] facial nerve ( Chvostek's Sign ) Symptoms bones fractures stones nephrolithiasis groans anorexia vomiting constipation psychic overtones weakness fatigue altered mental status Evaluation Evaluation EKG may show prolonged QT interval Lab differential workup [medbullets.com]

Albuterol Glucose & insulin Sodium bicarbonate Dialysis IV diuretics B) Bleeding Likely platelet dysfunction secondary to uremia: Desmopressin 0.3-0.4mcg/kg (max dose 20mcg) C) Pulmonary edema IV nitro glycerin and NIPPV Dialysis D) Infection Sepsis workup [canadiem.org]

Ferraro PM, D'Addessi A, Gambaro G: Randall's plaques, plugs and the clinical workup of the renal stone patient. Urolithiasis. 2015; 43 (Suppl 1): 59–61. PubMed Abstract Publisher Full Text 24. [doi.org]

• Lymphocytic Infiltrate

  infiltration, and secondary dilatation of collecting ducts. [ncbi.nlm.nih.gov]

This clinically oriented reference focuses on diagnosis and treatment of specific diseases, disorders, and complications and incorporates the basic science practicing physicians need to evaluate and manage the disease process. [books.google.de]

The pathogenesis and treatment of vitamin D intoxication is discussed. Received January 22, 1957. Accepted July 25, 1957. [pediatrics.aappublications.org]

Completely revised and updated with 80 all-new chapters covering the most important information on current diagnostic, treatment, and preventive challenges facing feline practitioners today, Consultations in Feline Internal Medicine is an invaluable addition [books.google.com]

Treatment will involve methods to reduce abnormal levels of calcium, phosphate, and oxalate in the blood and urine. Options include making changes in your diet and taking medicines and supplements. [nlm.nih.gov]

Finally, compliance to a prolonged pharmacological treatment remains a serious limitation of all forms of long-term treatment for a chronic disease, for which treatment effectiveness is conditioned by an efficient follow-up organization. [doi.org]

Prognosis The prognosis depends mainly on the aetiology of the nephrocalcinosis. [patient.info]

Prognosis for complete recovery of renal function is excellent if treatment is initiated rapidly. In patients with normal cardiac and renal function, treatment is usually with allopurinol plus aggressive IV hydration with normal saline. [merckmanuals.com]

Malignancy-associated hypercalcemia occurs in up to 10% of all patients with advanced cancer and generally conveys a poor prognosis. Indeed, the 30-day mortality rate for cancer patients with hypercalcemia is approximately 50% 2. [jemds.com]

The prognosis of nephrocalcinosis is determined by the underlying cause. [en.wikipedia.org]

Prognosis, therapy and follow-up Prognosis: Although end-stage renal disease (ESRD) requiring some form of renal replacement therapy is uncommon, the sarcoidosis cannot necessarily be considered a benign nephrologic condition. [peertechz.com]

Can affect the cortex as well as the medulla depending on the etiology Vishal Golay's 10. [slideshare.net]

Proximal renal tubular acidosis: a not so rare disorder of multiple etiologies. Nephrol. Dial. Transplant. 27, 4273–4287 (2012). Polanco NA, Soto-Abraham MV, Rodríguez-Castellanos FE. [revistas.unc.edu.ar]

Pathogenesis and etiologic factors The etiology and pathophysiology of sarcoidosis has not been fully understood. The noncaseating epithelioid cell granuloma is the principal lesion found in organs affected by sarcoidosis [18]. [peertechz.com]

Howard : The etiology of hypercalcemia associated with lung carcinoma. J. clin. Invest. 35, 697–698 (1956). Google Scholar Dahl, L. K. : The stages in calcification of the rat kidney after the administration of uranium nitrate. J. exp. [springerlink.com]

Trinchieri A: Epidemiology of urolithiasis: an update. Clin Cases Miner Bone Metab. 2008; 5 (2): 101–6. PubMed Abstract Free Full Text 2. Curhan GC: Epidemiology of stone disease. Urol Clin North Am. 2007; 34 (3): 287–93. [doi.org]

Epidemiology Microscopic nephrocalcinosis is a common incidental finding at post-mortem but macroscopic nephrocalcinosis is uncommon. [patient.info]

[…] lead to autonomous secretion from individual nodules Therapy with Vitamin D and Ca-based binders These therapies are often associated with hypercalcemia, especially when the extra calcium load is not taken up by bone (such as in adynamic bone disease) Epidemiology [renalandurologynews.com]

This review will summarize the epidemiologic, pathophysiologic, diagnostic, clinical, and therapeutic aspects of RS. [peertechz.com]

Each disease-oriented section begins with an up-to-date review of pathophysiology and then focuses on specific diseases. [books.google.de]

Abstract Our purpose here is to test the hypothesis that Randall's plaques, calcium phosphate deposits in kidneys of patients with calcium renal stones, arise in unique anatomical regions of the kidney, their formation conditioned by specific stone-forming pathophysiologies [ncbi.nlm.nih.gov]

While the pathophysiology is plausible, the more likely explanation might be true-true and unrelated. [nephronpower.com]

The pathophysiology of the initial-site crystallization may well be linked to hypercalciuria. [doi.org]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

Medical and Dental Schools 1010 Pharmacological considerations for renal failure and dialysis 1018 Anaesthesia and major surgery in patients with renal failure 1077 Management of the uremic diabetic patient 1107 A Peter Lundin M D 1115 Introduction 1120 Prevention [books.google.de]

Prompt treatment of disorders that lead to nephrocalcinosis, including RTA, may help prevent it from developing. Drinking plenty of water to keep the kidneys flushed and draining will help prevent or decrease stone formation as well. [nlm.nih.gov]

[…] antihypertensive measures, blockade of the raas by means of ace inhibitors or angiotensin ii receptor antagonists recently emerged as a potentially polyvalent approach, not only for treating hypertension and reducing cardiovascular events, but also to prevent [dict.site]